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Cheap flights from Panama City to Santiago from $328

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Panama City to Santiago departing on 8/2. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Panama City to Santiago

Cheap round-trip flights

KAYAK's recommended round-trip deals from the most popular airlines that fly from Panama City to Santiago.
3:20 am - 1:25 pmPTY-SCL
9h 05m1 stop
2:30 pm - 12:10 amSCL-PTY
10h 40m1 stop
$496Avianca
Find Deal
Thu, Apr 10 - Sun, Apr 13
7:11 pm - 2:47 amPTY-SCL
6h 36mnonstop
4:11 am - 10:03 amSCL-PTY
6h 52mnonstop
$497Copa Airlines
Find Deal
Thu, May 1 - Sat, May 31
9:28 pm - 5:04 amPTY-SCL
6h 36mnonstop
2:24 am - 8:16 amSCL-PTY
6h 52mnonstop
$523Copa Airlines
Find Deal
Sat, Jun 14 - Fri, Jun 20
3:20 am - 1:25 pmPTY-SCL
9h 05m1 stop
6:10 am - 9:10 pmSCL-PTY
16h 00m1 stop
$533Avianca
Find Deal
Wed, Apr 30 - Sat, May 31
3:20 am - 1:25 pmPTY-SCL
9h 05m1 stop
2:30 pm - 12:10 amSCL-PTY
10h 40m1 stop
$545Avianca
Find Deal
Wed, Apr 30 - Sat, May 31
11:48 am - 7:24 pmPTY-SCL
6h 36mnonstop
4:11 am - 10:03 amSCL-PTY
6h 52mnonstop
$555Copa Airlines
Find Deal
Thu, May 1 - Sat, May 31
3:20 am - 1:25 pmPTY-SCL
9h 05m1 stop
5:55 am - 7:15 pmSCL-PTY
14h 20m2 stops
$561Avianca
Find Deal
Thu, Apr 10 - Sun, Apr 13
3:08 pm - 10:44 pmPTY-SCL
6h 36mnonstop
12:13 am - 6:05 amSCL-PTY
6h 52mnonstop
$580Copa Airlines
Find Deal
Sat, May 24 - Fri, Jun 6
7:11 pm - 2:47 amPTY-SCL
6h 36mnonstop
4:17 am - 10:03 amSCL-PTY
6h 46mnonstop
$587Copa Airlines
Find Deal
Sat, Apr 26 - Wed, Apr 30
3:20 am - 5:00 amPTY-SCL
24h 40m2 stops
10:10 pm - 4:30 pmSCL-PTY
19h 20m2 stops
Thu, Apr 10 - Sun, Apr 13

Copa Airlines flights from Panama City to Santiago

Our best Copa Airlines deals on Panama City to Santiago flight tickets
Copa Airlines
May 1
PTY7:11 pmPanama City Tocumen Intl
6h 36m
SCL2:47 amSantiago Arturo Merino Benitez
May 31
SCL4:11 amSantiago Arturo Merino Benitez
6h 52m
PTY10:03 amPanama City Tocumen Intl
Copa Airlines
Jun 14
PTY9:28 pmPanama City Tocumen Intl
6h 36m
SCL5:04 amSantiago Arturo Merino Benitez
Jun 20
SCL2:24 amSantiago Arturo Merino Benitez
6h 52m
PTY8:16 amPanama City Tocumen Intl
Copa Airlines
May 1
PTY11:48 amPanama City Tocumen Intl
6h 36m
SCL7:24 pmSantiago Arturo Merino Benitez
May 31
SCL4:11 amSantiago Arturo Merino Benitez
6h 52m
PTY10:03 amPanama City Tocumen Intl

Avianca flights from Panama City to Santiago

Our best Avianca deals on Panama City to Santiago flight tickets
Avianca
Apr 10
PTY3:20 amPanama City Tocumen Intl
9h 05m
1 stop
SCL1:25 pmSantiago Arturo Merino Benitez
Apr 13
SCL2:30 pmSantiago Arturo Merino Benitez
10h 40m
1 stop
PTY12:10 amPanama City Tocumen Intl
Avianca
Apr 3
PTY3:20 amPanama City Tocumen Intl
9h 05m
1 stop
SCL2:25 pmSantiago Arturo Merino Benitez
Apr 6
SCL5:55 amSantiago Arturo Merino Benitez
11h 35m
1 stop
PTY4:30 pmPanama City Tocumen Intl
Avianca
Apr 2
PTY10:05 pmPanama City Tocumen Intl
14h 20m
1 stop
SCL2:25 pmSantiago Arturo Merino Benitez
Apr 14
SCL11:55 pmSantiago Arturo Merino Benitez
17h 35m
1 stop
PTY4:30 pmPanama City Tocumen Intl

See travel insights to Santiago from

How to get the cheapest flight ticket from Panama City to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Panama City and Santiago?

What is the cheapest month to fly to Santiago?

In general, August is the cheapest month to fly from Panama City to Santiago. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $453. If you don’t want to visit Santiago in August, then you should wait until May to fly from Panama City, when ticket prices are also cheap, with an average price of $467.

What is the cheapest day to depart on your flight to Santiago?

The cheapest day to depart on your flight to Santiago is on a Sunday when prices can be found for as low as $526. This is often the case because there is less demand to fly during this day of the week. Be sure to avoid booking your departure on a Wednesday as prices are generally higher than usual. According to our data, the average ticket price to Santiago on Wednesday is $651.

What is the cheapest time of day to depart on your flight to Santiago?

In the afternoon is the cheapest time of day to fly from Panama City to Santiago when you can find flight prices for as low as $526. Flying to Santiago in the afternoon is an ideal time because this is during off-peak travel hours. In the evening is when there is more demand to fly to Santiago, so prices are often more expensive at around $609 per ticket.

What is the cheapest Panama City Tocumen Intl to Santiago Arturo Merino Benitez flight route?

Fly from Panama City Tocumen Intl to Santiago Arturo Merino Benitez for the best Panama City Tocumen Intl - Santiago Arturo Merino Benitez flight prices

How far in advance should I book a flight to Santiago?

You are more likely to see cheaper flights to Santiago from Panama City when booking 19 weeks ahead of your departure date. In general, you can expect to find flights to Santiago for around $515 when searching 19 weeks out.However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santiago from Panama City for as low as $428 on momondo.

What cabin class options are available on Panama City Tocumen Intl to Santiago Arturo Merino Benitez flights?

There are 2 cabin classes available to choose from on Panama City Tocumen Intl to Santiago Arturo Merino Benitez flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

How have Panama City to Santiago flight prices changed over time?

As of April 2025, prices for Panama City to Santiago flights are approximately 14% more expensive when compared to flights at the same time last year.

When to book flights from Panama City to Santiago

Are you open to changing your travel dates? Check out the ideal times to fly from Panama City to Santiago according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Panama City to Santiago (PTY to SCL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama City to Santiago

Best Price Found

$328

Fastest flight time

6h 32m

Direct flights

Mon, Tue, Wed, Fri, Sat and Sun

Airports in Santiago

1 airport
The best one-way flight to Santiago from Panama City in the past 72 hours is $328. The best round-trip flight deal from Panama City to Santiago found on momondo in the last 72 hours is $496.
The fastest flight from Panama City to Santiago takes 6h 32m
Direct flights go from Panama City to Santiago on Monday, Tuesday, Wednesday, Friday, Saturday and Sunday. The only airline offering direct flights is Copa Airlines.
There is 1 airport near Santiago: Santiago Arturo Merino Benitez (SCL)

  • How far is Panama City Tocumen Intl to Santiago Arturo Merino Benitez by plane?

    Santiago Arturo Merino Benitez is 2987.0 mi away from Panama City Tocumen Intl. In terms of flight time, this usually takes a little over 6h 32m.

  • When did momondo last update prices for flights from Panama City Tocumen Intl Airport to Santiago Arturo Merino Benitez Airport?

    Prices for flights from Panama City Tocumen Intl Airport to Santiago Arturo Merino Benitez Airport are updated daily.

  • How many operators does momondo search for flights from Panama City Tocumen Intl Airport to Santiago Arturo Merino Benitez Airport?

  • How old do you have to be to fly from Panama City Tocumen Intl Airport to Santiago Arturo Merino Benitez Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Panama City Tocumen Intl Airport to Santiago Arturo Merino Benitez Airport.

  • What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

    The necessary travel and health documents for your Santiago Arturo Merino Benitez Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Panama City to Santiago?

  • What is the most popular airline from Panama City to Santiago?


Best airlines flying from Panama City to Santiago

Compare and see reviews for airlines that fly from Panama City to Santiago with momondo
Airline
Rating
Free Cancellation
Price
AviancaPriceFrom $294Free CancellationRating
6.7
2,301 reviews
Search Avianca flights
Copa AirlinesPriceFrom $370Free CancellationRating
7.6
1,400 reviews
Search Copa Airlines flights
  • Copa Airlines Flights From Panama City to Santiago

    Across 24 Copa Airlines flights from Panama City to Santiago this week, the average price was $592, with the best Copa Airlines deals starting from $370 round-trip. 1,400 users have rated Copa Airlines on momondo, with an average score of 7.6/10.


Traveling to a place near Santiago?

Book flights to Santiago if you plan to visit one of these locations
Viña del Mar
Valparaíso
Santa Cruz
San Fernando
Valle Nevado
Pichilemu

Why use momondo?

Why should I use momondo to find a flight deal from Panama City to Santiago?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Panama City to Santiago. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Panama City to Santiago with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Panama City to Santiago flights to just show those with flexible booking policies.

How can momondo help me find flights from Panama City to Santiago?

momondo provides multiple filters to help you find the best flight to Santiago from Panama City. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Panama City to Santiago right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Santiago from Panama City. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.


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