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Cheap flights from Panama City to San Francisco from $259

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Panama City to San Francisco departing on 4/29. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Panama City to San Francisco

Cheap round-trip flights

KAYAK's recommended round-trip deals from the most popular airlines that fly from Panama City to San Francisco.
3:40 pm - 10:45 pmPTY-SFO
9h 05m1 stop
2:20 pm - 10:10 amSFO-PTY
17h 50m2 stops
$460Avianca
Find Deal
Thu, May 22 - Tue, May 27
3:40 pm - 11:55 pmPTY-SFO
10h 15m1 stop
2:20 pm - 10:25 amSFO-PTY
18h 05m1 stop
$470Avianca
Find Deal
Thu, May 22 - Tue, May 27
10:05 pm - 10:15 pmPTY-SFO
26h 10m2 stops
2:20 pm - 10:25 amSFO-PTY
18h 05m1 stop
Fri, Apr 18 - Mon, Apr 21
3:20 am - 9:55 pmPTY-SFO
20h 35m2 stops
2:20 pm - 10:25 amSFO-PTY
18h 05m1 stop
Thu, Apr 17 - Mon, Apr 21
3:15 pm - 8:58 pmPTY-SFO
7h 43mnonstop
12:43 am - 2:14 pmSFO-PTY
11h 31m1 stop
$617United Airlines
Find Deal
Thu, May 22 - Mon, May 26
3:15 pm - 8:58 pmPTY-SFO
7h 43mnonstop
6:55 pm - 4:12 pmSFO-PTY
19h 17m1 stop
$632United Airlines
Find Deal
Sun, Jun 8 - Thu, Jun 26
1:50 pm - 8:36 amPTY-SFO
20h 46m2 stops
4:47 pm - 1:00 pmSFO-PTY
18h 13m2 stops
$640American Airlines
Find Deal
Sun, Jun 8 - Thu, Jun 26
1:50 pm - 11:13 amPTY-SFO
23h 23m1 stop
4:47 pm - 1:00 pmSFO-PTY
18h 13m2 stops
$657American Airlines
Find Deal
Sun, Jun 8 - Thu, Jun 26
5:50 pm - 11:40 pmPTY-SFO
7h 50mnonstop
1:37 am - 10:41 amSFO-PTY
7h 04mnonstop
$745Copa Airlines
Find Deal
Sun, May 25 - Wed, May 28
12:38 pm - 6:30 pmPTY-SFO
7h 52mnonstop
1:40 am - 10:41 amSFO-PTY
7h 01mnonstop
$817Copa Airlines
Find Deal
Thu, Apr 17 - Sun, Apr 20

Avianca flights from Panama City to San Francisco

Our best Avianca deals on Panama City to San Francisco flight tickets
Avianca
May 22
PTY3:40 pmPanama City Tocumen Intl
9h 05m
1 stop
SFO10:45 pmSan Francisco
May 27
SFO2:20 pmSan Francisco
17h 50m
2 stops
PTY10:10 amPanama City Tocumen Intl
Avianca
May 22
PTY3:40 pmPanama City Tocumen Intl
10h 15m
1 stop
SFO11:55 pmSan Francisco
May 27
SFO2:20 pmSan Francisco
18h 05m
1 stop
PTY10:25 amPanama City Tocumen Intl
Avianca
Apr 17
PTY3:40 pmPanama City Tocumen Intl
10h 15m
1 stop
SFO11:55 pmSan Francisco
Apr 28
SFO12:05 amSan Francisco
14h 25m
2 stops
PTY4:30 pmPanama City Tocumen Intl

United Airlines flights from Panama City to San Francisco

Our best United Airlines deals on Panama City to San Francisco flight tickets
United Airlines
May 22
PTY3:15 pmPanama City Tocumen Intl
7h 43m
SFO8:58 pmSan Francisco
May 26
SFO12:43 amSan Francisco
11h 31m
1 stop
PTY2:14 pmPanama City Tocumen Intl
United Airlines
Jun 8
PTY3:15 pmPanama City Tocumen Intl
7h 43m
SFO8:58 pmSan Francisco
Jun 26
SFO6:55 pmSan Francisco
19h 17m
1 stop
PTY4:12 pmPanama City Tocumen Intl
United Airlines
Jun 8
PTY3:15 pmPanama City Tocumen Intl
7h 43m
SFO8:58 pmSan Francisco
Jun 24
SFO5:15 amSan Francisco
8h 57m
1 stop
PTY4:12 pmPanama City Tocumen Intl

See travel insights to San Francisco from

How to get the cheapest flight ticket from Panama City to San Francisco

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to San Francisco?

If you aren’t able to travel to San Francisco during the month of May, then flying in August is also cheap. Prices for this month can be found on momondo for an average of $603.

What is the cheapest day to depart on your flight to San Francisco?

The cheapest day to depart from Panama City to San Francisco is on a Thursday when prices can be found for as low as $619. The most expensive day to fly to San Francisco is Tuesday, with ticket prices averaging around $780.

What is the cheapest time of day to depart on your flight to San Francisco?

Our data shows that the cheapest Panama City to San Francisco flights are usually those with departure times in the evening. Our users have found flights to San Francisco in the evening for as low as $433. Flights in the afternoon are often more expensive with an average ticket price of $673.

What is the cheapest Panama City Tocumen Intl to San Francisco flight route?

Fly from Panama City Tocumen Intl to San Francisco for the best Panama City Tocumen Intl - San Francisco flight prices

How far in advance should I book a flight to San Francisco?

You are more likely to see cheaper flights to San Francisco from Panama City when booking 20 weeks ahead of your departure date. In general, you can expect to find flights to San Francisco for around $639 when searching 20 weeks out.However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Francisco from Panama City for as low as $441 on momondo.

What cabin class options are available on Panama City Tocumen Intl to San Francisco flights?

There are 3 cabin classes available to choose from on Panama City Tocumen Intl to San Francisco flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

How have Panama City to San Francisco flight prices changed over time?

As of March 2025, prices for Panama City to San Francisco flights are approximately 110% more expensive when compared to flights at the same time last year.

When to book flights from Panama City to San Francisco

Are you open to changing your travel dates? Check out the ideal times to fly from Panama City to San Francisco according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Panama City to San Francisco (PTY to SFO) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama City to San Francisco

Best Price Found

$259

Fastest flight time

7h 43m

Direct flights

Mon, Wed, Thu, Fri, Sat and Sun

Airports in San Francisco

1 airport
The best one-way flight to San Francisco from Panama City in the past 72 hours is $259. The best round-trip flight deal from Panama City to San Francisco found on momondo in the last 72 hours is $460.
The fastest flight from Panama City to San Francisco takes 7h 43m
Direct flights go from Panama City to San Francisco on Monday, Wednesday, Thursday, Friday, Saturday and Sunday. Airlines offering direct flights are: United Airlines and Copa Airlines.
There is 1 airport near San Francisco: San Francisco (SFO)

  • How far is Panama City Tocumen Intl to San Francisco by plane?

    Panama City Tocumen Intl and San Francisco are 3322.3 mi apart from one another. By plane, this route typically takes 7h 43m.

  • When did momondo last update prices for flights from Panama City Tocumen Intl Airport to San Francisco Airport?

    Prices for flights from Panama City Tocumen Intl Airport to San Francisco Airport are updated daily.

  • How many operators does momondo search for flights from Panama City Tocumen Intl Airport to San Francisco Airport?

  • How old do you have to be to fly from Panama City Tocumen Intl Airport to San Francisco Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Panama City Tocumen Intl Airport to San Francisco Airport.

  • What documentation or ID do you need to fly to San Francisco Airport?

    The necessary travel and health documents for your San Francisco Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Panama City to San Francisco?

  • What is the most popular airline from Panama City to San Francisco?


Best airlines flying from Panama City to San Francisco

Compare and see reviews for airlines that fly from Panama City to San Francisco with momondo
Airline
Rating
Free Cancellation
Price
AviancaPriceFrom $341Free CancellationRating
6.7
2,298 reviews
Search Avianca flights
Copa AirlinesPriceFrom $554Free CancellationRating
7.6
1,393 reviews
Search Copa Airlines flights
United AirlinesPriceFrom $610Free CancellationRating
7.4
8,605 reviews
Search United Airlines flights
  • Copa Airlines Flights From Panama City to San Francisco

    Copa Airlines is one of the most popular airlines flying from Panama City to San Francisco, operating 7 flights/week on average for this route. A good Copa Airlines flight deal for Panama City to San Francisco starts from $554 round-trip, up to an average price of $630. Our users have rated Copa Airlines at 7.6/10.

  • United Airlines Flights From Panama City to San Francisco

    Across 8,605 United Airlines reviews on momondo, the average score is 7.4/10. United Airlines flies from Panama City to San Francisco about 7 times each week, with ticket deals ranging from $610 to $843. Price data is based on momondo searches in the last 72 hours.


Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
Santa Cruz
Carmel-by-the-Sea
Hayward
Modesto
Calistoga
Roseville
Santa Clara
Daly City
Sonoma
Fremont
South San Francisco
Bodega Bay
Sunnyvale
Redwood City
Big Sur
Vallejo
Berkeley
Walnut Creek
Palo Alto
Half Moon Bay

Why use momondo?

Why should I use momondo to find a flight deal from Panama City to San Francisco?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to San Francisco from Panama City.

Can I find flights from Panama City to San Francisco with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to San Francisco from Panama City with this policy.

How can momondo help me find flights from Panama City to San Francisco?

Once you have performed a search for Panama City to San Francisco flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Panama City to San Francisco right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Panama City to San Francisco flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.


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