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Cheap flights from Santo Domingo to Panama City from $188

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Santo Domingo to Panama City departing on 2/19. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Santo Domingo to Panama City

Cheap round-trip flights

These are some of the best round-trip flight deals from Santo Domingo to Panama City that have been recently found on momondo from popular airlines, departing in the coming months.

Cheap one-way flights

Flying one-way? These are some of the best deals recently discovered on momondo for flights from Santo Domingo to Panama City.

Cheap last minute flights

Planning a quick getaway from Santo Domingo to Panama City? These are the last-minute flight deals available now.

Cheap direct flights

If you prefer a non-stop journey, check out our latest direct flight deals to Panama City, so you can enjoy a seamless trip without layovers.

Cheap bus & train deals from Santo Domingo to Panama City

Find recent round-trip train or bus tickets from Santo Domingo to Panama City.

All round-trip flight deals from Santo Domingo to Panama City

The cheapest plane tickets from Santo Domingo to Panama City found on KAYAK recently.
11:50 am - 9:00 pmSDQ-PTY
10h 10m1 stop
3:19 am - 10:55 amPTY-SDQ
6h 36m1 stop
$406Avianca
Find Deal
Mon, Feb 10 - Fri, Feb 14
11:50 am - 4:30 pmSDQ-PTY
5h 40m1 stop
3:19 am - 10:55 amPTY-SDQ
6h 36m1 stop
$418Avianca
Find Deal
Tue, Feb 18 - Mon, Feb 24
11:50 am - 12:20 amSDQ-PTY
13h 30m1 stop
9:55 pm - 5:20 pmPTY-SDQ
18h 25m1 stop
$419Avianca
Find Deal
Mon, Feb 10 - Sat, Feb 15
11:50 am - 4:30 pmSDQ-PTY
5h 40m1 stop
3:19 am - 5:20 pmPTY-SDQ
13h 01m1 stop
$420Avianca
Find Deal
Mon, Mar 24 - Fri, Mar 28
6:18 am - 8:00 amSDQ-PTY
2h 42mnonstop
6:36 pm - 10:07 pmPTY-SDQ
2h 31mnonstop
$487Copa Airlines
Find Deal
Sat, Feb 22 - Sun, Mar 9
5:34 am - 7:12 amSDQ-PTY
2h 38mnonstop
7:26 am - 10:57 amPTY-SDQ
2h 31mnonstop
$526Copa Airlines
Find Deal
Sun, Apr 20 - Tue, May 13
11:50 am - 4:30 pmSDQ-PTY
5h 40m1 stop
3:34 pm - 10:05 pmPTY-SDQ
29h 31m2 stops
Mon, Mar 24 - Sat, Mar 29
3:40 pm - 2:40 pmSDQ-PTY
24h 00m2 stops
3:19 am - 5:20 pmPTY-SDQ
13h 01m1 stop
Sun, Feb 2 - Fri, Feb 14
1:55 pm - 4:07 pmSDQ-PTY
27h 12m2 stops
10:55 pm - 11:55 amPTY-SDQ
12h 00m1 stop
$1,413United Airlines
Find Deal
Fri, Mar 28 - Mon, Mar 31
2:55 pm - 5:07 pmSDQ-PTY
27h 12m2 stops
11:35 am - 2:49 amPTY-SDQ
14h 14m2 stops
$1,471United Airlines
Find Deal
Wed, Feb 19 - Wed, Feb 26
6:15 pm - 12:20 amSDQ-PTY
7h 05m1 stop
$188Avianca
Find Deal
Wed, Feb 19
10:02 am - 8:00 pmSDQ-PTY
10h 58m1 stop
Sun, Jan 26
6:18 pm - 5:09 pmSDQ-PTY
23h 51m2 stops
Sun, Jan 26
8:48 am - 10:30 amSDQ-PTY
2h 42mnonstop
$530Copa Airlines
Find Deal
Thu, Jan 30
10:57 pm - 6:36 amSDQ-PTY
8h 39m1 stop
12:00 pm - 7:24 pmPTY-SDQ
6h 24m1 stop
Sat, Jan 25 - Tue, Feb 11
10:57 pm - 6:36 amSDQ-PTY
8h 39m1 stop
10:26 pm - 7:24 pmPTY-SDQ
19h 58m1 stop
Sat, Jan 25 - Mon, Feb 10
10:57 pm - 6:36 amSDQ-PTY
8h 39m1 stop
10:30 pm - 9:12 amPTY-SDQ
9h 42m1 stop
Sat, Jan 25 - Sat, Feb 8
3:40 pm - 2:40 pmSDQ-PTY
24h 00m2 stops
3:19 am - 5:20 pmPTY-SDQ
13h 01m1 stop
Sun, Jan 26 - Tue, Jan 28
6:15 pm - 1:00 amSDQ-PTY
7h 45m1 stop
9:55 pm - 5:20 pmPTY-SDQ
18h 25m1 stop
$648Avianca
Find Deal
Thu, Jan 23 - Mon, Feb 10
6:15 pm - 9:40 amSDQ-PTY
16h 25m1 stop
3:19 am - 10:55 amPTY-SDQ
6h 36m1 stop
$649Avianca
Find Deal
Thu, Jan 23 - Sun, Feb 9
11:55 am - 1:30 pmSDQ-PTY
2h 35mnonstop
12:52 pm - 4:20 pmPTY-SDQ
2h 28mnonstop
$704Copa Airlines
Find Deal
Thu, Jan 23 - Mon, Feb 10
2:39 pm - 4:17 pmSDQ-PTY
2h 38mnonstop
10:13 pm - 1:37 amPTY-SDQ
2h 24mnonstop
$1,051Copa Airlines
Find Deal
Thu, Jan 23 - Fri, Feb 7
2:55 pm - 7:38 pmSDQ-PTY
29h 43m2 stops
11:35 am - 2:49 amPTY-SDQ
14h 14m2 stops
$2,101United Airlines
Find Deal
Fri, Jan 24 - Mon, Feb 10
3:22 pm - 8:01 pmSDQ-PTY
29h 39m1 stop
8:05 am - 12:56 amPTY-SDQ
39h 51m2 stops
$6,736Delta
Find Deal
Fri, Jan 24 - Sat, Feb 8
6:18 am - 8:00 amSDQ-PTY
2h 42mnonstop
6:36 pm - 10:07 pmPTY-SDQ
2h 31mnonstop
$487Copa Airlines
Find Deal
Sat, Feb 22 - Sun, Mar 9
5:34 am - 7:12 amSDQ-PTY
2h 38mnonstop
7:26 am - 10:57 amPTY-SDQ
2h 31mnonstop
$526Copa Airlines
Find Deal
Sun, Apr 20 - Tue, May 13
8:48 am - 10:30 amSDQ-PTY
2h 42mnonstop
12:52 pm - 4:20 pmPTY-SDQ
2h 28mnonstop
$621Copa Airlines
Find Deal
Sun, Feb 2 - Sun, Feb 9
11:55 am - 1:30 pmSDQ-PTY
2h 35mnonstop
12:52 pm - 4:20 pmPTY-SDQ
2h 28mnonstop
$704Copa Airlines
Find Deal
Mon, Feb 3 - Wed, Feb 5
5:28 am - 7:12 amSDQ-PTY
2h 44mnonstop
6:36 pm - 10:03 pmPTY-SDQ
2h 27mnonstop
$1,105Copa Airlines
Find Deal
Tue, Apr 1 - Mon, Apr 14

Avianca flights from Santo Domingo to Panama City

Our best Avianca deals on Santo Domingo to Panama City flight tickets
Avianca
Feb 10
SDQ11:50 amSanto Domingo Las Americas
10h 10m
1 stop
PTY9:00 pmPanama City Tocumen Intl
Feb 14
PTY3:19 amPanama City Tocumen Intl
6h 36m
1 stop
SDQ10:55 amSanto Domingo Las Americas
Avianca
Feb 18
SDQ11:50 amSanto Domingo Las Americas
5h 40m
1 stop
PTY4:30 pmPanama City Tocumen Intl
Feb 24
PTY3:19 amPanama City Tocumen Intl
6h 36m
1 stop
SDQ10:55 amSanto Domingo Las Americas
Avianca
Feb 10
SDQ11:50 amSanto Domingo Las Americas
13h 30m
1 stop
PTY12:20 amPanama City Tocumen Intl
Feb 15
PTY9:55 pmPanama City Tocumen Intl
18h 25m
1 stop
SDQ5:20 pmSanto Domingo Las Americas

Copa Airlines flights from Santo Domingo to Panama City

Our best Copa Airlines deals on Santo Domingo to Panama City flight tickets
Copa Airlines
Feb 22
SDQ6:18 amSanto Domingo Las Americas
2h 42m
PTY8:00 amPanama City Tocumen Intl
Mar 9
PTY6:36 pmPanama City Tocumen Intl
2h 31m
SDQ10:07 pmSanto Domingo Las Americas
Copa Airlines
Apr 20
SDQ5:34 amSanto Domingo Las Americas
2h 38m
PTY7:12 amPanama City Tocumen Intl
May 13
PTY7:26 amPanama City Tocumen Intl
2h 31m
SDQ10:57 amSanto Domingo Las Americas
Copa Airlines
Feb 2
SDQ8:48 amSanto Domingo Las Americas
2h 42m
PTY10:30 amPanama City Tocumen Intl
Feb 9
PTY12:52 pmPanama City Tocumen Intl
2h 28m
SDQ4:20 pmSanto Domingo Las Americas

See travel insights to Panama City from

How to get the cheapest flight ticket from Santo Domingo to Panama City

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Santo Domingo and Panama City?

What is the cheapest month to fly to Panama City?

In general, April is the cheapest month to fly from Santo Domingo to Panama City. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $370. If you’re not able to fly to Panama City in April, then May is your next best option. Flight prices from Santo Domingo to Panama City during May average around $370.

What is the cheapest day to depart on your flight to Panama City?

Our data shows that Tuesday is the least expensive day to fly to Panama City. Tickets to fly out on this day can be as low as $370. If your travel schedule is flexible, try to avoid departing on a Wednesday because tickets tend to average around $464. These prices are subject to change though, so be sure to set up a Price Alert for flights to Panama City.

What is the cheapest time of day to depart on your flight to Panama City?

Our most recent data shows that the best time of day to fly to Panama City is in the morning. Flights from Santo Domingo to Panama City during this time can be as low as $414. Try not to purchase tickets at noon because they tend to be around $421. Of course, these prices can vary depending on the time of year and what airport you fly to.

What is the cheapest Santo Domingo Las Americas to Panama City Tocumen Intl flight route?

Fly from Santo Domingo Las Americas to Panama City Tocumen Intl for the best Santo Domingo Las Americas - Panama City Tocumen Intl flight prices

How far in advance should I book a flight to Panama City?

You are more likely to see cheaper flights to Panama City from Santo Domingo when booking 22 weeks ahead of your departure date. In general, you can expect to find flights to Panama City for around $419 when searching 22 weeks out.However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama City from Santo Domingo for as low as $375 on momondo.

What cabin class options are available on Santo Domingo Las Americas to Panama City Tocumen Intl flights?

There are 3 cabin classes available to choose from on Santo Domingo Las Americas to Panama City Tocumen Intl flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

How have Santo Domingo to Panama City flight prices changed over time?

As of January 2025, prices for Santo Domingo to Panama City flights are approximately 48% more expensive when compared to flights at the same time last year.

When to book flights from Santo Domingo to Panama City

Are you open to changing your travel dates? Check out the ideal times to fly from Santo Domingo to Panama City according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Santo Domingo to Panama City (SDQ to PTY) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santo Domingo to Panama City

Best Price Found

$188

Fastest flight time

2h 35m

Direct flights

Mon, Tue, Wed and Sun

Airports in Panama City

1 airport
The best one-way flight to Panama City from Santo Domingo in the past 72 hours is $188. The best round-trip flight deal from Santo Domingo to Panama City found on momondo in the last 72 hours is $406.
The fastest flight from Santo Domingo to Panama City takes 2h 35m
Direct flights go from Santo Domingo to Panama City on Monday, Tuesday, Wednesday and Sunday. The only airline offering direct flights is Copa Airlines.
There is 1 airport near Panama City: Panama City Tocumen Intl (PTY)

  • How far is Santo Domingo Las Americas to Panama City Tocumen Intl by plane?

    The straight-line distance from Santo Domingo Las Americas to Panama City Tocumen Intl is 918.3 mi. Flights usually cover this in 2h 35m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Santo Domingo Las Americas Airport to Panama City Tocumen Intl Airport?

    Prices for flights from Santo Domingo Las Americas Airport to Panama City Tocumen Intl Airport were last updated today.

  • How many operators does momondo search for flights from Santo Domingo Las Americas Airport to Panama City Tocumen Intl Airport?

  • How old do you have to be to fly from Santo Domingo Las Americas Airport to Panama City Tocumen Intl Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Santo Domingo Las Americas Airport to Panama City Tocumen Intl Airport.

  • What documentation or ID do you need to fly to Panama City Tocumen Intl Airport?

    The necessary travel and health documents for your Panama City Tocumen Intl Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Santo Domingo to Panama City?

  • What is the most popular airline from Santo Domingo to Panama City?


Best airlines flying from Santo Domingo to Panama City

Compare and see reviews for airlines that fly from Santo Domingo to Panama City with momondo
Airline
Rating
Free Cancellation
Price
AviancaPriceFrom $299Free CancellationRating
6.9
2,579 reviews
Search Avianca flights
Copa AirlinesPriceFrom $364Free CancellationRating
7.6
1,662 reviews
Search Copa Airlines flights
  • Copa Airlines Flights From Santo Domingo to Panama City

    Copa Airlines flies from Santo Domingo to Panama City around 25 times per week, with 1,662 momondo users rating the airline 7.6/10. The cheapest Copa Airlines deal from Santo Domingo to Panama City in the last 72 hours was $364 (round-trip), much lower than the average airfare cost of $421 for Copa Airlines flights on this route.


Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
San Blas

Why use momondo?

Why should I use momondo to find a flight deal from Santo Domingo to Panama City?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Santo Domingo to Panama City. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Santo Domingo to Panama City with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Panama City from Santo Domingo with this policy.

How can momondo help me find flights from Santo Domingo to Panama City?

Once all potential Santo Domingo to Panama City flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Santo Domingo to Panama City right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Santo Domingo to Panama City flights. All you need is a valid email address and we will do the rest; it is that quick and easy.


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