Latest deals
Insights
When to book
FAQs
Reviews
Price Alerts

Cheap flights from Santo Domingo to Panama City from $138

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Santo Domingo to Panama City departing on 4/30. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.

Find the cheapest flights from Santo Domingo to Panama City

Cheap round-trip flights

KAYAK's recommended round-trip deals from the most popular airlines that fly from Santo Domingo to Panama City.
Avianca Logo
11:45 am - 4:30 pmSDQ-PTY
5h 45m1 stop
Avianca Logo
9:50 am - 5:15 pmPTY-SDQ
6h 25m1 stop
$305Avianca
Find Deal
Thu, May 1 - Thu, May 8
Avianca Logo
6:10 pm - 12:10 amSDQ-PTY
7h 00m1 stop
Avianca Logo
3:20 am - 10:50 amPTY-SDQ
6h 30m1 stop
$317Avianca
Find Deal
Wed, May 14 - Wed, May 14
Copa Airlines Logo
5:21 am - 6:58 amSDQ-PTY
2h 37mnonstop
Copa Airlines Logo
11:13 pm - 2:45 amPTY-SDQ
2h 32mnonstop
$415Copa Airlines
Find Deal
Thu, May 8 - Tue, May 13
Copa Airlines Logo
5:21 am - 6:58 amSDQ-PTY
2h 37mnonstop
Copa Airlines Logo
7:26 am - 10:57 amPTY-SDQ
2h 31mnonstop
$430Copa Airlines
Find Deal
Thu, May 1 - Thu, May 8
 Logo
6:10 pm - 12:10 amSDQ-PTY
7h 00m1 stop
 Logo
8:10 pm - 2:19 pmPTY-SDQ
17h 09m2 stops
Tue, Apr 29 - Tue, May 6
 Logo
11:45 am - 9:10 pmSDQ-PTY
10h 25m1 stop
 Logo
5:25 pm - 2:50 pmPTY-SDQ
20h 25m2 stops
Thu, May 1 - Thu, May 8
United Airlines Logo
1:10 pm - 2:14 pmSDQ-PTY
26h 04m2 stops
United Airlines Logo
7:55 am - 1:50 amPTY-SDQ
16h 55m2 stops
$1,031United Airlines
Find Deal
Thu, Jul 10 - Fri, Jul 25
United Airlines Logo
1:10 pm - 2:19 pmSDQ-PTY
26h 09m2 stops
United Airlines Logo
10:00 am - 1:50 amPTY-SDQ
14h 50m2 stops
$1,422United Airlines
Find Deal
Thu, Sep 25 - Tue, Sep 30
Delta Logo
3:02 pm - 12:55 pmSDQ-PTY
22h 53m2 stops
Delta Logo
2:13 pm - 6:28 pmPTY-SDQ
27h 15m2 stops
$6,452Delta
Find Deal
Mon, May 5 - Sun, May 11
Delta Logo
2:09 pm - 12:49 pmSDQ-PTY
23h 40m2 stops
Delta Logo
2:14 pm - 12:30 amPTY-SDQ
33h 16m2 stops
$6,498Delta
Find Deal
Wed, Sep 10 - Thu, Sep 18

Avianca flights from Santo Domingo to Panama City

Our best Avianca deals on Santo Domingo to Panama City flight tickets
Avianca
May 1
SDQ11:45 amSanto Domingo Las Americas
5h 45m
1 stop
PTY4:30 pmPanama City Tocumen Intl
May 8
PTY9:50 amPanama City Tocumen Intl
6h 25m
1 stop
SDQ5:15 pmSanto Domingo Las Americas
Avianca
May 14
SDQ6:10 pmSanto Domingo Las Americas
7h 00m
1 stop
PTY12:10 amPanama City Tocumen Intl
May 14
PTY3:20 amPanama City Tocumen Intl
6h 30m
1 stop
SDQ10:50 amSanto Domingo Las Americas
Avianca
May 5
SDQ11:45 amSanto Domingo Las Americas
13h 25m
1 stop
PTY12:10 amPanama City Tocumen Intl
Jun 4
PTY3:20 amPanama City Tocumen Intl
6h 30m
1 stop
SDQ10:50 amSanto Domingo Las Americas

Copa Airlines flights from Santo Domingo to Panama City

Our best Copa Airlines deals on Santo Domingo to Panama City flight tickets
Copa Airlines
May 8
SDQ5:21 amSanto Domingo Las Americas
2h 37m
PTY6:58 amPanama City Tocumen Intl
May 13
PTY11:13 pmPanama City Tocumen Intl
2h 32m
SDQ2:45 amSanto Domingo Las Americas
Copa Airlines
May 1
SDQ5:21 amSanto Domingo Las Americas
2h 37m
PTY6:58 amPanama City Tocumen Intl
May 8
PTY7:26 amPanama City Tocumen Intl
2h 31m
SDQ10:57 amSanto Domingo Las Americas
Copa Airlines
Apr 18
SDQ8:52 amSanto Domingo Las Americas
2h 38m
PTY10:30 amPanama City Tocumen Intl
Apr 22
PTY11:13 pmPanama City Tocumen Intl
2h 27m
SDQ2:40 amSanto Domingo Las Americas

See travel insights to Panama City from

How to get the cheapest flight ticket from Santo Domingo to Panama City

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Panama City?

In general, May is the cheapest month to fly from Santo Domingo to Panama City. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $370. If you’re not able to fly to Panama City in May, then June is your next best option. Flight prices from Santo Domingo to Panama City during June average around $370.

What is the cheapest day to depart on your flight to Panama City?

Our data shows that Wednesday is the least expensive day to fly to Panama City. Tickets to fly out on this day can be as low as $376. If your travel schedule is flexible, try to avoid departing on a Monday because tickets tend to average around $468. These prices are subject to change though, so be sure to set up a Price Alert for flights to Panama City.

What is the cheapest time of day to depart on your flight to Panama City?

Our most recent data shows that the best time of day to fly to Panama City is in the afternoon. Flights from Santo Domingo to Panama City during this time can be as low as $385. Try not to purchase tickets at noon because they tend to be around $452. Of course, these prices can vary depending on the time of year and what airport you fly to.

What is the cheapest Santo Domingo Las Americas to Panama City Tocumen Intl flight route?

Fly from Santo Domingo Las Americas to Panama City Tocumen Intl for the best Santo Domingo Las Americas - Panama City Tocumen Intl flight prices

How far in advance should I book a flight to Panama City?

You are more likely to see cheaper flights to Panama City from Santo Domingo when booking 25 weeks ahead of your departure date. In general, you can expect to find flights to Panama City for around $440 when searching 25 weeks out.However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama City from Santo Domingo for as low as $406 on momondo.

What cabin class options are available on Santo Domingo Las Americas to Panama City Tocumen Intl flights?

There are 3 cabin classes available to choose from on Santo Domingo Las Americas to Panama City Tocumen Intl flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

How have Santo Domingo to Panama City flight prices changed over time?

As of April 2025, prices for Santo Domingo to Panama City flights are approximately 36% more expensive when compared to flights at the same time last year.

When to book flights from Santo Domingo to Panama City

Are you open to changing your travel dates? Check out the ideal times to fly from Santo Domingo to Panama City according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Santo Domingo to Panama City (SDQ to PTY) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santo Domingo to Panama City

Best Price Found

$138

Fastest flight time

2h 35m

Direct flights

Every day

Airports in Panama City

1 airport
The best one-way flight to Panama City from Santo Domingo in the past 72 hours is $138. The best round-trip flight deal from Santo Domingo to Panama City found on momondo in the last 72 hours is $305.
The fastest flight from Santo Domingo to Panama City takes 2h 35m
Direct flights go from Santo Domingo to Panama City every day.
There is 1 airport near Panama City: Panama City Tocumen Intl (PTY)

  • How far is Santo Domingo Las Americas to Panama City Tocumen Intl by plane?

    The straight-line distance from Santo Domingo Las Americas to Panama City Tocumen Intl is 918.3 mi. Flights usually cover this in 2h 35m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Santo Domingo Las Americas Airport to Panama City Tocumen Intl Airport?

    Prices for flights from Santo Domingo Las Americas Airport to Panama City Tocumen Intl Airport were last updated today.

  • How many operators does momondo search for flights from Santo Domingo Las Americas Airport to Panama City Tocumen Intl Airport?

  • How old do you have to be to fly from Santo Domingo Las Americas Airport to Panama City Tocumen Intl Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Santo Domingo Las Americas Airport to Panama City Tocumen Intl Airport.

  • What documentation or ID do you need to fly to Panama City Tocumen Intl Airport?

    The necessary travel and health documents for your Panama City Tocumen Intl Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Santo Domingo to Panama City?

  • What is the most popular airline from Santo Domingo to Panama City?


Best airlines flying from Santo Domingo to Panama City

Compare and see reviews for airlines that fly from Santo Domingo to Panama City with momondo
Airline
Rating
Free Cancellation
Price
AviancaPriceFrom $304Free CancellationRating
6.7
2,301 reviews
Search Avianca flights
Copa AirlinesPriceFrom $370Free CancellationRating
7.6
1,400 reviews
Search Copa Airlines flights
  • Copa Airlines Flights From Santo Domingo to Panama City

    Copa Airlines flies from Santo Domingo to Panama City around 24 times per week, with 1,400 momondo users rating the airline 7.6/10. The cheapest Copa Airlines deal from Santo Domingo to Panama City in the last 72 hours was $370 (round-trip), much lower than the average airfare cost of $484 for Copa Airlines flights on this route.


Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
San Blas

Why use momondo?

Why should I use momondo to find a flight deal from Santo Domingo to Panama City?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Santo Domingo to Panama City. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Santo Domingo to Panama City with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Panama City from Santo Domingo with this policy.

How can momondo help me find flights from Santo Domingo to Panama City?

Once all potential Santo Domingo to Panama City flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Santo Domingo to Panama City right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Santo Domingo to Panama City flights. All you need is a valid email address and we will do the rest; it is that quick and easy.


An easier way to manage your Panama City trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
From?
To?
Mon 4/7
Mon 4/14

Find better results for your trip to Panama