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Cheap flights from San Francisco to Santiago from $310

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from San Francisco to Santiago departing on 3/13. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from San Francisco to Santiago

Cheap round-trip flights

These are some of the best round-trip flight deals from San Francisco to Santiago that have been recently found on momondo from popular airlines, departing in the coming months.
1:51 am - 3:39 amSFO-SCL
21h 48m1 stop
5:33 am - 11:40 pmSCL-SFO
22h 07m1 stop
$652Copa Airlines
Find Deal
Tue, Mar 18 - Wed, Mar 26
11:51 am - 7:00 amSFO-SCL
16h 09m1 stop
8:40 pm - 3:45 pmSCL-SFO
22h 05m1 stop
$664Delta
Find Deal
Wed, Apr 23 - Mon, Apr 28
6:10 am - 7:00 amSFO-SCL
21h 50m2 stops
8:40 pm - 3:08 pmSCL-SFO
21h 28m2 stops
$668LATAM Airlines
Find Deal
Thu, Apr 24 - Tue, Apr 29
1:51 am - 12:13 amSFO-SCL
18h 22m1 stop
5:33 am - 11:40 pmSCL-SFO
22h 07m1 stop
$672Copa Airlines
Find Deal
Thu, Mar 13 - Wed, Mar 19
7:30 am - 7:00 amSFO-SCL
20h 30m1 stop
12:30 am - 11:45 amSCL-SFO
38h 15m2 stops
$676LATAM Airlines
Find Deal
Tue, May 13 - Mon, May 19
7:05 am - 6:55 amSFO-SCL
20h 50m2 stops
9:55 pm - 10:54 pmSCL-SFO
27h 59m1 stop
$707American Airlines
Find Deal
Sun, Apr 20 - Thu, Apr 24
2:30 am - 11:30 pmSFO-SCL
17h 00m2 stops
2:30 pm - 11:55 pmSCL-SFO
36h 25m2 stops
$721Avianca
Find Deal
Tue, Apr 1 - Mon, Apr 14
2:30 am - 1:25 pmSFO-SCL
31h 55m2 stops
2:30 pm - 10:45 pmSCL-SFO
35h 15m2 stops
$729Avianca
Find Deal
Thu, May 15 - Mon, May 26
10:20 am - 8:00 amSFO-SCL
17h 40m2 stops
9:55 pm - 5:08 pmSCL-SFO
22h 13m2 stops
$867American Airlines
Find Deal
Wed, Apr 2 - Sun, Apr 13
11:00 am - 7:50 amSFO-SCL
16h 50m1 stop
9:45 pm - 7:24 amSCL-SFO
37h 39m1 stop
$923United Airlines
Find Deal
Wed, Mar 19 - Sat, Mar 29

American Airlines flights from San Francisco to Santiago

Our best American Airlines deals on San Francisco to Santiago flight tickets
American Airlines
Apr 20
SFO7:05 amSan Francisco
20h 50m
2 stops
SCL6:55 amSantiago Arturo Merino Benitez
Apr 24
SCL9:55 pmSantiago Arturo Merino Benitez
27h 59m
1 stop
SFO10:54 pmSan Francisco
American Airlines
Apr 2
SFO10:20 amSan Francisco
17h 40m
2 stops
SCL8:00 amSantiago Arturo Merino Benitez
Apr 13
SCL9:55 pmSantiago Arturo Merino Benitez
22h 13m
2 stops
SFO5:08 pmSan Francisco
American Airlines
Feb 28
SFO11:50 pmSan Francisco
27h 00m
1 stop
SCL7:50 amSantiago Arturo Merino Benitez
Mar 10
SCL10:44 pmSantiago Arturo Merino Benitez
24h 16m
1 stop
SFO7:00 pmSan Francisco

Copa Airlines flights from San Francisco to Santiago

Our best Copa Airlines deals on San Francisco to Santiago flight tickets
Copa Airlines
Mar 18
SFO1:51 amSan Francisco
21h 48m
1 stop
SCL3:39 amSantiago Arturo Merino Benitez
Mar 26
SCL5:33 amSantiago Arturo Merino Benitez
22h 07m
1 stop
SFO11:40 pmSan Francisco
Copa Airlines
Mar 13
SFO1:51 amSan Francisco
18h 22m
1 stop
SCL12:13 amSantiago Arturo Merino Benitez
Mar 19
SCL5:33 amSantiago Arturo Merino Benitez
22h 07m
1 stop
SFO11:40 pmSan Francisco
Copa Airlines
May 16
SFO1:37 amSan Francisco
18h 07m
1 stop
SCL10:44 pmSantiago Arturo Merino Benitez
May 31
SCL2:24 amSantiago Arturo Merino Benitez
24h 16m
1 stop
SFO11:40 pmSan Francisco

See travel insights to Santiago from

How to get the cheapest flight ticket from San Francisco to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Santiago?

In general, May is the cheapest month to fly from San Francisco to Santiago. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $732. If you don’t want to visit Santiago in May, then you should wait until April to fly from San Francisco, when ticket prices are also cheap, with an average price of $747.

What is the cheapest day to depart on your flight to Santiago?

The cheapest day to depart on your flight to Santiago is on a Wednesday when prices can be found for as low as $812. This is often the case because there is less demand to fly during this day of the week. Be sure to avoid booking your departure on a Saturday as prices are generally higher than usual. According to our data, the average ticket price to Santiago on Saturday is $1,066.

What is the cheapest time of day to depart on your flight to Santiago?

In the evening is the cheapest time of day to fly from San Francisco to Santiago when you can find flight prices for as low as $831. Flying to Santiago in the evening is an ideal time because this is during off-peak travel hours. At noon is when there is more demand to fly to Santiago, so prices are often more expensive at around $1,007 per ticket.

How far in advance should I book a flight to Santiago?

You are more likely to see cheaper flights to Santiago from San Francisco when booking 8 weeks ahead of your departure date. In general, you can expect to find flights to Santiago for around $884 when searching 8 weeks out.However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santiago from San Francisco for as low as $807 on momondo.

How have San Francisco to Santiago flight prices changed over time?

As of February 2025, prices for San Francisco to Santiago flights are approximately 20% more expensive when compared to flights at the same time last year.

When to book flights from San Francisco to Santiago

Are you open to changing your travel dates? Check out the ideal times to fly from San Francisco to Santiago according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap San Francisco to Santiago (SFO to SCL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from San Francisco to Santiago

Best Price Found

$310

Fastest flight time

14h 23m

Direct flights

None

Airports in Santiago

1 airport
The best one-way flight to Santiago from San Francisco in the past 72 hours is $310. The best round-trip flight deal from San Francisco to Santiago found on momondo in the last 72 hours is $652.
The fastest flight from San Francisco to Santiago takes 14h 23m
There are no direct flights from San Francisco to Santiago. Popular non-direct route for this connection is San Francisco Airport - Santiago Arturo Merino Benitez Airport.
There is 1 airport near Santiago: Santiago Arturo Merino Benitez (SCL)

  • How far is San Francisco to Santiago Arturo Merino Benitez by plane?

    A flight from San Francisco to Santiago Arturo Merino Benitez will travel around 5935.3 mi. In terms of flight time, this usually takes a little over 14h 23m.

  • When did momondo last update prices for flights from San Francisco Airport to Santiago Arturo Merino Benitez Airport?

    Prices for flights from San Francisco Airport to Santiago Arturo Merino Benitez Airport were last updated today.

  • How many operators does momondo search for flights from San Francisco Airport to Santiago Arturo Merino Benitez Airport?

  • How old do you have to be to fly from San Francisco Airport to Santiago Arturo Merino Benitez Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from San Francisco Airport to Santiago Arturo Merino Benitez Airport.

  • What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

    The necessary travel and health documents for your Santiago Arturo Merino Benitez Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from San Francisco to Santiago?


Best airlines flying from San Francisco to Santiago

Compare and see reviews for airlines that fly from San Francisco to Santiago with momondo
Airline
Rating
Free Cancellation
Price
AviancaPriceFrom $478Free CancellationRating
6.8
2,381 reviews
Search Avianca flights
Copa AirlinesPriceFrom $534Free CancellationRating
7.6
1,483 reviews
Search Copa Airlines flights
United AirlinesPriceFrom $622Free CancellationRating
7.4
8,724 reviews
Search United Airlines flights
DeltaPriceFrom $650Free CancellationRating
8.0
8,138 reviews
Search Delta flights
American AirlinesPriceFrom $658Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights
LATAM AirlinesPriceFrom $662Free CancellationRating
7.5
1,771 reviews
Search LATAM Airlines flights
AeromexicoPriceFrom $783Free CancellationRating
7.4
1,753 reviews
Search Aeromexico flights

Traveling to a place near Santiago?

Book flights to Santiago if you plan to visit one of these locations
Viña del Mar
Valparaíso
Santa Cruz
San Fernando
Valle Nevado
Pichilemu

Why use momondo?

Why should I use momondo to find a flight deal from San Francisco to Santiago?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Santiago from San Francisco.

Can I find flights from San Francisco to Santiago with flexible booking policies on momondo?

Flights from San Francisco to Santiago with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from San Francisco to Santiago?

Once all potential San Francisco to Santiago flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from San Francisco to Santiago right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Santiago from San Francisco. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.


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