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Cheap flights from San Francisco to Santiago from $310

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from San Francisco to Santiago departing on 4/14. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from San Francisco to Santiago

Cheap round-trip flights

KAYAK's recommended round-trip deals from the most popular airlines that fly from San Francisco to Santiago.
1:40 am - 7:24 pmSFO-SCL
14h 44m1 stop
4:11 am - 11:40 pmSCL-SFO
22h 29m1 stop
$652Copa Airlines
Find Deal
Fri, Apr 25 - Sat, May 3
8:11 pm - 10:44 pmSFO-SCL
23h 33m1 stop
12:19 am - 6:30 pmSCL-SFO
21h 11m1 stop
$656Copa Airlines
Find Deal
Tue, Apr 15 - Thu, Apr 17
12:05 am - 4:15 amSFO-SCL
25h 10m2 stops
11:55 pm - 10:45 pmSCL-SFO
25h 50m2 stops
$659Avianca
Find Deal
Thu, Apr 24 - Fri, May 2
12:05 am - 10:30 pmSFO-SCL
19h 25m2 stops
11:55 pm - 10:45 pmSCL-SFO
25h 50m2 stops
$661Avianca
Find Deal
Mon, May 5 - Wed, May 28
7:00 am - 6:45 amSFO-SCL
20h 45m1 stop
10:45 pm - 5:47 pmSCL-SFO
22h 02m1 stop
$664Delta
Find Deal
Tue, Aug 19 - Tue, Aug 26
10:20 am - 6:55 amSFO-SCL
17h 35m2 stops
9:00 pm - 6:58 pmSCL-SFO
24h 58m2 stops
$668American Airlines
Find Deal
Tue, May 20 - Tue, May 27
1:20 pm - 6:55 amSFO-SCL
14h 35m1 stop
9:00 pm - 4:59 pmSCL-SFO
22h 59m2 stops
$688American Airlines
Find Deal
Tue, May 6 - Wed, May 28
7:30 am - 7:00 amSFO-SCL
20h 30m1 stop
10:45 pm - 9:59 amSCL-SFO
14h 14m1 stop
$689Delta
Find Deal
Thu, May 29 - Sun, Jun 8
6:00 am - 7:00 amSFO-SCL
22h 00m1 stop
12:40 am - 11:32 pmSCL-SFO
25h 52m2 stops
$764LATAM Airlines
Find Deal
Mon, May 5 - Thu, May 8
8:55 am - 2:10 pmSFO-SCL
26h 15m2 stops
8:40 am - 3:16 pmSCL-SFO
33h 36m3 stops
$768LATAM Airlines
Find Deal
Mon, May 5 - Fri, May 9

American Airlines flights from San Francisco to Santiago

Our best American Airlines deals on San Francisco to Santiago flight tickets
American Airlines
May 20
SFO10:20 amSan Francisco
17h 35m
2 stops
SCL6:55 amSantiago Arturo Merino Benitez
May 27
SCL9:00 pmSantiago Arturo Merino Benitez
24h 58m
2 stops
SFO6:58 pmSan Francisco
American Airlines
May 6
SFO1:20 pmSan Francisco
14h 35m
1 stop
SCL6:55 amSantiago Arturo Merino Benitez
May 28
SCL9:00 pmSantiago Arturo Merino Benitez
22h 59m
2 stops
SFO4:59 pmSan Francisco
American Airlines
Apr 17
SFO1:18 pmSan Francisco
14h 37m
1 stop
SCL6:55 amSantiago Arturo Merino Benitez
May 2
SCL9:55 pmSantiago Arturo Merino Benitez
25h 41m
1 stop
SFO8:36 pmSan Francisco

Copa Airlines flights from San Francisco to Santiago

Our best Copa Airlines deals on San Francisco to Santiago flight tickets
Copa Airlines
Apr 25
SFO1:40 amSan Francisco
14h 44m
1 stop
SCL7:24 pmSantiago Arturo Merino Benitez
May 3
SCL4:11 amSantiago Arturo Merino Benitez
22h 29m
1 stop
SFO11:40 pmSan Francisco
Copa Airlines
Apr 15
SFO8:11 pmSan Francisco
23h 33m
1 stop
SCL10:44 pmSantiago Arturo Merino Benitez
Apr 17
SCL12:19 amSantiago Arturo Merino Benitez
21h 11m
1 stop
SFO6:30 pmSan Francisco
Copa Airlines
May 4
SFO1:37 amSan Francisco
24h 27m
1 stop
SCL5:04 amSantiago Arturo Merino Benitez
May 8
SCL2:24 amSantiago Arturo Merino Benitez
24h 16m
1 stop
SFO11:40 pmSan Francisco

See travel insights to Santiago from

How to get the cheapest flight ticket from San Francisco to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Santiago?

In general, May is the cheapest month to fly from San Francisco to Santiago. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $732. If you don’t want to visit Santiago in May, then you should wait until April to fly from San Francisco, when ticket prices are also cheap, with an average price of $752.

What is the cheapest day to depart on your flight to Santiago?

The cheapest day to depart on your flight to Santiago is on a Wednesday when prices can be found for as low as $812. This is often the case because there is less demand to fly during this day of the week. Be sure to avoid booking your departure on a Saturday as prices are generally higher than usual. According to our data, the average ticket price to Santiago on Saturday is $1,066.

What is the cheapest time of day to depart on your flight to Santiago?

In the evening is the cheapest time of day to fly from San Francisco to Santiago when you can find flight prices for as low as $831. Flying to Santiago in the evening is an ideal time because this is during off-peak travel hours. At noon is when there is more demand to fly to Santiago, so prices are often more expensive at around $1,007 per ticket.

How far in advance should I book a flight to Santiago?

You are more likely to see cheaper flights to Santiago from San Francisco when booking 8 weeks ahead of your departure date. In general, you can expect to find flights to Santiago for around $876 when searching 8 weeks out.However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santiago from San Francisco for as low as $794 on momondo.

How have San Francisco to Santiago flight prices changed over time?

As of March 2025, prices for San Francisco to Santiago flights are approximately 49% more expensive when compared to flights at the same time last year.

When to book flights from San Francisco to Santiago

Are you open to changing your travel dates? Check out the ideal times to fly from San Francisco to Santiago according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap San Francisco to Santiago (SFO to SCL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from San Francisco to Santiago

Best Price Found

$310

Fastest flight time

14h 00m

Direct flights

None

Airports in Santiago

1 airport
The best one-way flight to Santiago from San Francisco in the past 72 hours is $310. The best round-trip flight deal from San Francisco to Santiago found on momondo in the last 72 hours is $652.
The fastest flight from San Francisco to Santiago takes 14h 00m
There are no direct flights from San Francisco to Santiago. Popular non-direct route for this connection is San Francisco Airport - Santiago Arturo Merino Benitez Airport.
There is 1 airport near Santiago: Santiago Arturo Merino Benitez (SCL)

  • How far is San Francisco to Santiago Arturo Merino Benitez by plane?

    A flight from San Francisco to Santiago Arturo Merino Benitez will travel around 5935.3 mi. In terms of flight time, this usually takes a little over 14h 00m.

  • When did momondo last update prices for flights from San Francisco Airport to Santiago Arturo Merino Benitez Airport?

    Prices for flights from San Francisco Airport to Santiago Arturo Merino Benitez Airport were last updated today.

  • How many operators does momondo search for flights from San Francisco Airport to Santiago Arturo Merino Benitez Airport?

  • How old do you have to be to fly from San Francisco Airport to Santiago Arturo Merino Benitez Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from San Francisco Airport to Santiago Arturo Merino Benitez Airport.

  • What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

    The necessary travel and health documents for your Santiago Arturo Merino Benitez Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from San Francisco to Santiago?


Best airlines flying from San Francisco to Santiago

Compare and see reviews for airlines that fly from San Francisco to Santiago with momondo
Airline
Rating
Free Cancellation
Price
AviancaPriceFrom $478Free CancellationRating
6.7
2,300 reviews
Search Avianca flights
Copa AirlinesPriceFrom $535Free CancellationRating
7.5
1,395 reviews
Search Copa Airlines flights
United AirlinesPriceFrom $622Free CancellationRating
7.4
8,603 reviews
Search United Airlines flights
DeltaPriceFrom $644Free CancellationRating
8.0
7,895 reviews
Search Delta flights
American AirlinesPriceFrom $658Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights
LATAM AirlinesPriceFrom $660Free CancellationRating
7.5
1,750 reviews
Search LATAM Airlines flights
AeromexicoPriceFrom $765Free CancellationRating
7.4
1,701 reviews
Search Aeromexico flights

Traveling to a place near Santiago?

Book flights to Santiago if you plan to visit one of these locations
Viña del Mar
Valparaíso
Santa Cruz
San Fernando
Valle Nevado
Pichilemu

Why use momondo?

Why should I use momondo to find a flight deal from San Francisco to Santiago?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Santiago from San Francisco.

Can I find flights from San Francisco to Santiago with flexible booking policies on momondo?

Flights from San Francisco to Santiago with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from San Francisco to Santiago?

Once all potential San Francisco to Santiago flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from San Francisco to Santiago right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Santiago from San Francisco. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.


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