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Cheap flights from San Francisco to Santiago from $289

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from San Francisco to Santiago departing on 3/20. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from San Francisco to Santiago

Cheap round-trip flights

These are some of the best round-trip flight deals from San Francisco to Santiago that have been recently found on momondo from popular airlines, departing in the coming months.

Cheap one-way flights

Flying one-way? These are some of the best deals recently discovered on momondo for flights from San Francisco to Santiago.

Cheap last minute flights

Planning a quick getaway from San Francisco to Santiago? These are the last-minute flight deals available now.

Cheap direct flights

If you prefer a non-stop journey, check out our latest direct flight deals to Santiago, so you can enjoy a seamless trip without layovers.

Cheap bus & train deals from San Francisco to Santiago

Find recent round-trip train or bus tickets from San Francisco to Santiago.

All round-trip flight deals from San Francisco to Santiago

The cheapest plane tickets from San Francisco to Santiago found on KAYAK recently.
2:20 pm - 1:40 amSFO-SCL
31h 20m3 stops
3:05 am - 10:55 pmSCL-SFO
23h 50m3 stops
$617Avianca
Find Deal
Sun, Mar 16 - Wed, Mar 19
12:15 am - 1:40 amSFO-SCL
21h 25m3 stops
3:05 am - 10:55 pmSCL-SFO
23h 50m3 stops
$632Avianca
Find Deal
Sat, Mar 15 - Wed, Mar 19
1:51 am - 6:00 amSFO-SCL
24h 09m1 stop
1:32 am - 11:40 pmSCL-SFO
26h 08m1 stop
$652Copa Airlines
Find Deal
Sun, Mar 9 - Tue, Mar 18
7:39 am - 7:05 amSFO-SCL
20h 26m1 stop
9:55 pm - 8:36 pmSCL-SFO
25h 41m1 stop
$664American Airlines
Find Deal
Tue, Apr 8 - Tue, Apr 15
7:01 am - 8:00 amSFO-SCL
20h 59m1 stop
9:55 pm - 5:08 pmSCL-SFO
22h 13m2 stops
$668American Airlines
Find Deal
Wed, Apr 2 - Mon, Apr 14
8:11 pm - 7:24 pmSFO-SCL
20h 13m1 stop
2:30 am - 6:30 pmSCL-SFO
19h 00m1 stop
$678Copa Airlines
Find Deal
Tue, Apr 15 - Wed, Apr 23
6:00 am - 5:30 amSFO-SCL
20h 30m2 stops
8:40 pm - 5:14 pmSCL-SFO
23h 34m1 stop
$684Delta
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Tue, May 27 - Tue, Jun 3
6:00 am - 7:00 amSFO-SCL
22h 00m2 stops
8:40 pm - 3:15 pmSCL-SFO
21h 35m2 stops
$688LATAM Airlines
Find Deal
Wed, May 28 - Mon, Jun 2
11:05 am - 5:50 amSFO-SCL
15h 45m1 stop
10:55 pm - 3:15 pmSCL-SFO
19h 20m1 stop
$709LATAM Airlines
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Sun, May 25 - Mon, Jun 2
6:00 am - 7:00 amSFO-SCL
22h 00m1 stop
8:40 pm - 6:02 pmSCL-SFO
24h 22m1 stop
$753Delta
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Thu, Apr 10 - Thu, Apr 24
2:20 pm - 1:40 amSFO-SCL
31h 20m3 stops
$289Avianca
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Thu, Mar 20
2:20 pm - 1:40 amSFO-SCL
31h 20m2 stops
$308Avianca
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Thu, Mar 20
1:51 am - 6:00 amSFO-SCL
24h 09m1 stop
$309Copa Airlines
Find Deal
Tue, Mar 25
7:13 pm - 8:19 pmSFO-SCL
20h 06m1 stop
$310Copa Airlines
Find Deal
Tue, Jan 28
12:15 am - 1:40 amSFO-SCL
21h 25m2 stops
$325Avianca
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Tue, Mar 25
10:11 am - 9:14 amSFO-SCL
18h 03m2 stops
$408American Airlines
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Fri, Feb 7
6:45 am - 7:49 amSFO-SCL
20h 04m2 stops
$411American Airlines
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Tue, Jan 28
6:00 am - 7:20 amSFO-SCL
20h 20m1 stop
$418Delta
Find Deal
Sat, Feb 22
4:22 pm - 7:20 amSFO-SCL
33h 58m2 stops
$469LATAM Airlines
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Sun, Feb 16
11:45 pm - 7:00 amSFO-SCL
28h 15m3 stops
$488LATAM Airlines
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Fri, May 16
8:27 am - 11:25 amSFO-SCL
21h 58m2 stops
11:15 pm - 1:49 pmSCL-SFO
19h 34m1 stop
$799LATAM Airlines
Find Deal
Mon, Jan 27 - Wed, Jan 29
6:00 am - 1:30 pmSFO-SCL
26h 30m3 stops
11:15 pm - 10:35 amSCL-SFO
16h 20m1 stop
$826LATAM Airlines
Find Deal
Mon, Jan 27 - Wed, Jan 29
7:00 am - 9:14 amSFO-SCL
21h 14m1 stop
11:45 pm - 6:04 pmSCL-SFO
23h 19m1 stop
$854American Airlines
Find Deal
Sun, Jan 26 - Fri, Feb 7
10:11 am - 7:49 amSFO-SCL
16h 38m2 stops
10:30 pm - 10:46 amSCL-SFO
17h 16m1 stop
$858American Airlines
Find Deal
Sun, Jan 26 - Fri, Feb 7
12:44 am - 12:13 amSFO-SCL
18h 29m1 stop
12:27 pm - 5:33 pmSCL-SFO
34h 06m1 stop
$1,018Copa Airlines
Find Deal
Sun, Jan 26 - Wed, Jan 29
12:44 am - 6:00 amSFO-SCL
24h 16m1 stop
12:27 pm - 11:24 pmSCL-SFO
15h 57m1 stop
$1,036Copa Airlines
Find Deal
Sat, Jan 25 - Fri, Feb 7
6:00 am - 7:20 amSFO-SCL
20h 20m1 stop
12:45 am - 9:55 pmSCL-SFO
26h 10m2 stops
$1,042
Find Deal
Fri, Jan 24 - Thu, Jan 30
6:05 am - 5:40 amSFO-SCL
18h 35m2 stops
12:45 am - 9:55 pmSCL-SFO
26h 10m2 stops
$1,055
Find Deal
Fri, Jan 24 - Thu, Jan 30
1:20 pm - 2:20 pmSFO-SCL
20h 00m2 stops
12:45 am - 12:00 pmSCL-SFO
40h 15m2 stops
$1,075Avianca
Find Deal
Mon, Jan 27 - Tue, Jan 28
1:35 am - 11:40 pmSFO-SCL
17h 05m2 stops
3:25 pm - 12:00 pmSCL-SFO
25h 35m2 stops
$1,339Avianca
Find Deal
Sat, Jan 25 - Fri, Feb 7

Avianca flights from San Francisco to Santiago

Our best Avianca deals on San Francisco to Santiago flight tickets
Avianca
Mar 16
SFO2:20 pmSan Francisco
31h 20m
3 stops
SCL1:40 amSantiago Arturo Merino Benitez
Mar 19
SCL3:05 amSantiago Arturo Merino Benitez
23h 50m
3 stops
SFO10:55 pmSan Francisco
Avianca
Mar 15
SFO12:15 amSan Francisco
21h 25m
3 stops
SCL1:40 amSantiago Arturo Merino Benitez
Mar 19
SCL3:05 amSantiago Arturo Merino Benitez
23h 50m
3 stops
SFO10:55 pmSan Francisco
Avianca
May 13
SFO2:20 pmSan Francisco
29h 10m
2 stops
SCL10:30 pmSantiago Arturo Merino Benitez
May 19
SCL2:30 pmSantiago Arturo Merino Benitez
36h 25m
2 stops
SFO11:55 pmSan Francisco

Delta flights from San Francisco to Santiago

Our best Delta deals on San Francisco to Santiago flight tickets
Delta
May 27
SFO6:00 amSan Francisco
20h 30m
2 stops
SCL5:30 amSantiago Arturo Merino Benitez
Jun 3
SCL8:40 pmSantiago Arturo Merino Benitez
23h 34m
1 stop
SFO5:14 pmSan Francisco
Delta
Apr 10
SFO6:00 amSan Francisco
22h 00m
1 stop
SCL7:00 amSantiago Arturo Merino Benitez
Apr 24
SCL8:40 pmSantiago Arturo Merino Benitez
24h 22m
1 stop
SFO6:02 pmSan Francisco
Delta
Apr 11
SFO8:30 amSan Francisco
18h 30m
1 stop
SCL6:00 amSantiago Arturo Merino Benitez
Apr 24
SCL8:40 pmSantiago Arturo Merino Benitez
24h 22m
1 stop
SFO6:02 pmSan Francisco

See travel insights to Santiago from

How to get the cheapest flight ticket from San Francisco to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Santiago?

In general, May is the cheapest month to fly from San Francisco to Santiago. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $759. If you don’t want to visit Santiago in May, then you should wait until April to fly from San Francisco, when ticket prices are also cheap, with an average price of $762.

What is the cheapest day to depart on your flight to Santiago?

The cheapest day to depart on your flight to Santiago is on a Wednesday when prices can be found for as low as $812. This is often the case because there is less demand to fly during this day of the week. Be sure to avoid booking your departure on a Saturday as prices are generally higher than usual. According to our data, the average ticket price to Santiago on Saturday is $1,066.

What is the cheapest time of day to depart on your flight to Santiago?

In the evening is the cheapest time of day to fly from San Francisco to Santiago when you can find flight prices for as low as $831. Flying to Santiago in the evening is an ideal time because this is during off-peak travel hours. At noon is when there is more demand to fly to Santiago, so prices are often more expensive at around $1,007 per ticket.

How far in advance should I book a flight to Santiago?

You are more likely to see cheaper flights to Santiago from San Francisco when booking 17 weeks ahead of your departure date. In general, you can expect to find flights to Santiago for around $902 when searching 17 weeks out.However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santiago from San Francisco for as low as $814 on momondo.

How have San Francisco to Santiago flight prices changed over time?

As of January 2025, prices for San Francisco to Santiago flights are approximately 0% cheaper when compared to flights at the same time last year.

When to book flights from San Francisco to Santiago

Are you open to changing your travel dates? Check out the ideal times to fly from San Francisco to Santiago according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap San Francisco to Santiago (SFO to SCL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from San Francisco to Santiago

Best Price Found

$289

Fastest flight time

13h 58m

Direct flights

None

Airports in Santiago

1 airport
The best one-way flight to Santiago from San Francisco in the past 72 hours is $289. The best round-trip flight deal from San Francisco to Santiago found on momondo in the last 72 hours is $617.
The fastest flight from San Francisco to Santiago takes 13h 58m
There are no direct flights from San Francisco to Santiago. Popular non-direct route for this connection is San Francisco Airport - Santiago Arturo Merino Benitez Airport.
There is 1 airport near Santiago: Santiago Arturo Merino Benitez (SCL)

  • How far is San Francisco to Santiago Arturo Merino Benitez by plane?

    A flight from San Francisco to Santiago Arturo Merino Benitez will travel around 5935.3 mi. In terms of flight time, this usually takes a little over 13h 58m.

  • When did momondo last update prices for flights from San Francisco Airport to Santiago Arturo Merino Benitez Airport?

    Prices for flights from San Francisco Airport to Santiago Arturo Merino Benitez Airport were last updated today.

  • How many operators does momondo search for flights from San Francisco Airport to Santiago Arturo Merino Benitez Airport?

  • How old do you have to be to fly from San Francisco Airport to Santiago Arturo Merino Benitez Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from San Francisco Airport to Santiago Arturo Merino Benitez Airport.

  • What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

    The necessary travel and health documents for your Santiago Arturo Merino Benitez Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from San Francisco to Santiago?


Best airlines flying from San Francisco to Santiago

Compare and see reviews for airlines that fly from San Francisco to Santiago with momondo
Airline
Rating
Free Cancellation
Price
AviancaPriceFrom $478Free CancellationRating
6.9
2,565 reviews
Search Avianca flights
Copa AirlinesPriceFrom $489Free CancellationRating
7.6
1,653 reviews
Search Copa Airlines flights
United AirlinesPriceFrom $622Free CancellationRating
7.4
8,971 reviews
Search United Airlines flights
DeltaPriceFrom $648Free CancellationRating
8.0
8,507 reviews
Search Delta flights
American AirlinesPriceFrom $658Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights
LATAM AirlinesPriceFrom $662Free CancellationRating
7.5
1,851 reviews
Search LATAM Airlines flights
AeromexicoPriceFrom $783Free CancellationRating
7.5
1,847 reviews
Search Aeromexico flights

Traveling to a place near Santiago?

Book flights to Santiago if you plan to visit one of these locations
Viña del Mar
Valparaíso
Santa Cruz
San Fernando
Valle Nevado
Pichilemu

Why use momondo?

Why should I use momondo to find a flight deal from San Francisco to Santiago?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Santiago from San Francisco.

Can I find flights from San Francisco to Santiago with flexible booking policies on momondo?

Flights from San Francisco to Santiago with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from San Francisco to Santiago?

Once all potential San Francisco to Santiago flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from San Francisco to Santiago right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Santiago from San Francisco. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.


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