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Cheap flights from San Francisco to Santiago from $309

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from San Francisco to Santiago departing on 5/15. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from San Francisco to Santiago

Cheap round-trip flights

KAYAK's recommended round-trip deals from the most popular airlines that fly from San Francisco to Santiago.
LATAM Airlines Logo
6:00 am - 4:45 amSFO-SCL
19h 45m2 stops
LATAM Airlines Logo
10:45 pm - 9:57 amSCL-SFO
14h 12m1 stop
$637LATAM Airlines
Find Deal
mar., ago. 19 - mar., ago. 26
Copa Airlines Logo
1:37 am - 7:24 pmSFO-SCL
14h 47m1 stop
Copa Airlines Logo
4:11 am - 11:40 pmSCL-SFO
22h 29m1 stop
$652Copa Airlines
Find Deal
jue., may. 15 - vie., may. 23
Avianca Logo
12:05 am - 4:15 amSFO-SCL
25h 10m2 stops
Avianca Logo
6:10 am - 11:55 pmSCL-SFO
20h 45m2 stops
$682Avianca
Find Deal
mar., ago. 12 - sáb., ago. 23
Avianca Logo
12:05 am - 12:50 amSFO-SCL
21h 45m3 stops
Avianca Logo
6:10 am - 11:55 pmSCL-SFO
20h 45m2 stops
$684Avianca
Find Deal
mar., ago. 12 - sáb., ago. 23
Delta Logo
7:30 am - 7:00 amSFO-SCL
20h 30m1 stop
Delta Logo
8:40 pm - 5:19 pmSCL-SFO
23h 39m1 stop
$689Delta
Find Deal
mar., jul. 1 - dom., jul. 6
American Airlines Logo
9:15 am - 7:00 amSFO-SCL
18h 45m2 stops
American Airlines Logo
9:55 pm - 6:53 pmSCL-SFO
23h 58m2 stops
$695American Airlines
Find Deal
mar., jun. 24 - mar., jul. 1
 Logo
7:30 am - 7:00 amSFO-SCL
20h 30m1 stop
 Logo
8:20 am - 11:19 pmSCL-SFO
17h 59m1 stop
mar., jun. 24 - mar., jul. 1
 Logo
8:58 am - 6:00 amSFO-SCL
18h 02m1 stop
 Logo
10:45 pm - 8:49 amSCL-SFO
37h 04m2 stops
mié., jun. 4 - lun., jun. 23
Delta Logo
10:55 am - 6:00 amSFO-SCL
16h 05m1 stop
Delta Logo
11:05 pm - 11:55 pmSCL-SFO
27h 50m2 stops
$718Delta
Find Deal
vie., jun. 13 - dom., jun. 22
American Airlines Logo
1:06 pm - 7:05 amSFO-SCL
14h 59m1 stop
American Airlines Logo
9:55 pm - 1:29 pmSCL-SFO
18h 34m2 stops
$735American Airlines
Find Deal
mié., ago. 13 - sáb., ago. 23

Avianca flights from San Francisco to Santiago

Our best Avianca deals on San Francisco to Santiago flight tickets
Avianca
Aug 12
SFO12:05 amSan Francisco
25h 10m
2 stops
SCL4:15 amSantiago Arturo Merino Benitez
Aug 23
SCL6:10 amSantiago Arturo Merino Benitez
20h 45m
2 stops
SFO11:55 pmSan Francisco
Avianca
Aug 12
SFO12:05 amSan Francisco
21h 45m
3 stops
SCL12:50 amSantiago Arturo Merino Benitez
Aug 23
SCL6:10 amSantiago Arturo Merino Benitez
20h 45m
2 stops
SFO11:55 pmSan Francisco
Avianca
May 13
SFO2:30 amSan Francisco
17h 00m
2 stops
SCL10:30 pmSantiago Arturo Merino Benitez
May 22
SCL6:10 amSantiago Arturo Merino Benitez
19h 35m
2 stops
SFO10:45 pmSan Francisco

LATAM Airlines flights from San Francisco to Santiago

Our best LATAM Airlines deals on San Francisco to Santiago flight tickets
LATAM Airlines
Aug 19
SFO6:00 amSan Francisco
19h 45m
2 stops
SCL4:45 amSantiago Arturo Merino Benitez
Aug 26
SCL10:45 pmSantiago Arturo Merino Benitez
14h 12m
1 stop
SFO9:57 amSan Francisco
LATAM Airlines
Sep 8
SFO11:05 amSan Francisco
14h 55m
1 stop
SCL6:00 amSantiago Arturo Merino Benitez
Sep 22
SCL11:05 pmSantiago Arturo Merino Benitez
14h 55m
1 stop
SFO10:00 amSan Francisco
LATAM Airlines
Jun 11
SFO12:35 pmSan Francisco
14h 25m
1 stop
SCL6:00 amSantiago Arturo Merino Benitez
Jun 26
SCL11:00 amSantiago Arturo Merino Benitez
27h 43m
2 stops
SFO11:43 amSan Francisco

See travel insights to Santiago from

How to get the cheapest flight ticket from San Francisco to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between San Francisco and Santiago?

What is the cheapest month to fly to Santiago?

In general, May is the cheapest month to fly from San Francisco to Santiago. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $732. If you don’t want to visit Santiago in May, then you should wait until August to fly from San Francisco, when ticket prices are also cheap, with an average price of $793.

What is the cheapest day to depart on your flight to Santiago?

The cheapest day to depart on your flight to Santiago is on a Wednesday when prices can be found for as low as $812. This is often the case because there is less demand to fly during this day of the week. Be sure to avoid booking your departure on a Saturday as prices are generally higher than usual. According to our data, the average ticket price to Santiago on Saturday is $1,066.

What is the cheapest time of day to depart on your flight to Santiago?

In the evening is the cheapest time of day to fly from San Francisco to Santiago when you can find flight prices for as low as $831. Flying to Santiago in the evening is an ideal time because this is during off-peak travel hours. At noon is when there is more demand to fly to Santiago, so prices are often more expensive at around $1,007 per ticket.

How far in advance should I book a flight to Santiago?

You are more likely to see cheaper flights to Santiago from San Francisco when booking 8 weeks ahead of your departure date. In general, you can expect to find flights to Santiago for around $873 when searching 8 weeks out.However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santiago from San Francisco for as low as $793 on momondo.

How have San Francisco to Santiago flight prices changed over time?

As of April 2025, prices for San Francisco to Santiago flights are approximately 4% more expensive when compared to flights at the same time last year.

When to book flights from San Francisco to Santiago

Are you open to changing your travel dates? Check out the ideal times to fly from San Francisco to Santiago according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap San Francisco to Santiago (SFO to SCL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from San Francisco to Santiago

Best Price Found

$309

Fastest flight time

14h 10m

Direct flights

None

Airports in Santiago

1 airport
The best one-way flight to Santiago from San Francisco in the past 72 hours is $309. The best round-trip flight deal from San Francisco to Santiago found on momondo in the last 72 hours is $637.
The fastest flight from San Francisco to Santiago takes 14h 10m
There are no direct flights from San Francisco to Santiago. Popular non-direct route for this connection is San Francisco Airport - Santiago Arturo Merino Benitez Airport.
There is 1 airport near Santiago: Santiago Arturo Merino Benitez (SCL)

  • How far is San Francisco to Santiago Arturo Merino Benitez by plane?

    A flight from San Francisco to Santiago Arturo Merino Benitez will travel around 5935.3 mi. In terms of flight time, this usually takes a little over 14h 10m.

  • When did momondo last update prices for flights from San Francisco Airport to Santiago Arturo Merino Benitez Airport?

    Prices for flights from San Francisco Airport to Santiago Arturo Merino Benitez Airport were last updated today.

  • How many operators does momondo search for flights from San Francisco Airport to Santiago Arturo Merino Benitez Airport?

  • How old do you have to be to fly from San Francisco Airport to Santiago Arturo Merino Benitez Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from San Francisco Airport to Santiago Arturo Merino Benitez Airport.

  • What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

    The necessary travel and health documents for your Santiago Arturo Merino Benitez Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from San Francisco to Santiago?


Best airlines flying from San Francisco to Santiago

Compare and see reviews for airlines that fly from San Francisco to Santiago with momondo
Airline
Rating
Free Cancellation
Price
AviancaPriceFrom $473Free CancellationRating
6.7
2,316 reviews
Search Avianca flights
Copa AirlinesPriceFrom $537Free CancellationRating
7.5
1,409 reviews
Search Copa Airlines flights
United AirlinesPriceFrom $622Free CancellationRating
7.4
8,667 reviews
Search United Airlines flights
DeltaPriceFrom $642Free CancellationRating
8.0
7,916 reviews
Search Delta flights
American AirlinesPriceFrom $658Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights
LATAM AirlinesPriceFrom $659Free CancellationRating
7.5
1,761 reviews
Search LATAM Airlines flights
AeromexicoPriceFrom $765Free CancellationRating
7.4
1,699 reviews
Search Aeromexico flights

Traveling to a place near Santiago?

Book flights to Santiago if you plan to visit one of these locations
Viña del Mar
Valparaíso
Santa Cruz
San Fernando
Valle Nevado
Pichilemu

Why use momondo?

Why should I use momondo to find a flight deal from San Francisco to Santiago?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Santiago from San Francisco.

Can I find flights from San Francisco to Santiago with flexible booking policies on momondo?

Flights from San Francisco to Santiago with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from San Francisco to Santiago?

Once all potential San Francisco to Santiago flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from San Francisco to Santiago right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Santiago from San Francisco. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.


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mar. 4/22
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