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Cheap flights from San Francisco to Panama City from $219

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from San Francisco to Panama City departing on 4/28. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from San Francisco to Panama City

Cheap round-trip flights

These are some of the best round-trip flight deals from San Francisco to Panama City that have been recently found on momondo from popular airlines, departing in the coming months.

Cheap one-way flights

Flying one-way? These are some of the best deals recently discovered on momondo for flights from San Francisco to Panama City.

Cheap last minute flights

Planning a quick getaway from San Francisco to Panama City? These are the last-minute flight deals available now.

Cheap direct flights

If you prefer a non-stop journey, check out our latest direct flight deals to Panama City, so you can enjoy a seamless trip without layovers.

Cheap bus & train deals from San Francisco to Panama City

Find recent round-trip train or bus tickets from San Francisco to Panama City.

All round-trip flight deals from San Francisco to Panama City

The cheapest plane tickets from San Francisco to Panama City found on KAYAK recently.
12:15 am - 12:35 pmSFO-PTY
10h 20m2 stops
1:30 pm - 10:45 pmPTY-SFO
11h 15m2 stops
$524Avianca
Find Deal
Sun, Mar 23 - Wed, Apr 2
1:20 pm - 12:35 pmSFO-PTY
20h 15m2 stops
1:30 pm - 9:55 pmPTY-SFO
11h 25m2 stops
$534Avianca
Find Deal
Sat, Feb 8 - Tue, Feb 18
10:55 am - 8:10 pmSFO-PTY
7h 15mnonstop
3:15 pm - 8:58 pmPTY-SFO
7h 43mnonstop
$659United Airlines
Find Deal
Mon, Jun 23 - Tue, Jul 8
5:00 am - 4:12 pmSFO-PTY
9h 12m1 stop
3:40 pm - 11:59 pmPTY-SFO
10h 19m1 stop
$663United Airlines
Find Deal
Sun, Jun 22 - Wed, Jul 9
7:13 pm - 5:13 amSFO-PTY
7h 00mnonstop
6:27 pm - 11:24 pmPTY-SFO
7h 57mnonstop
$664Copa Airlines
Find Deal
Tue, Feb 18 - Fri, Feb 28
12:44 am - 10:46 amSFO-PTY
7h 02mnonstop
6:27 pm - 11:24 pmPTY-SFO
7h 57mnonstop
$674Copa Airlines
Find Deal
Mon, Feb 17 - Fri, Feb 28
11:59 pm - 2:40 pmSFO-PTY
12h 41m2 stops
1:15 pm - 9:27 amPTY-SFO
22h 12m2 stops
$678American Airlines
Find Deal
Sun, Mar 30 - Sat, Apr 5
2:33 pm - 2:02 pmSFO-PTY
20h 29m1 stop
8:05 am - 10:03 pmPTY-SFO
16h 58m1 stop
$688Delta
Find Deal
Thu, Feb 27 - Sat, Mar 8
6:30 pm - 12:15 pmSFO-PTY
15h 45m2 stops
1:15 pm - 9:27 amPTY-SFO
22h 12m2 stops
$693American Airlines
Find Deal
Wed, Apr 9 - Sat, Apr 19
2:33 pm - 2:02 pmSFO-PTY
20h 29m1 stop
8:05 am - 10:03 pmPTY-SFO
16h 58m1 stop
$703Delta
Find Deal
Wed, Feb 26 - Sat, Mar 8
11:53 pm - 12:10 amSFO-PTY
22h 17m3 stops
Mon, Apr 28
11:54 pm - 12:10 amSFO-PTY
22h 16m3 stops
Mon, Apr 28
1:20 pm - 12:35 pmSFO-PTY
20h 15m2 stops
$244Avianca
Find Deal
Tue, Feb 11
2:20 pm - 12:35 pmSFO-PTY
20h 15m2 stops
$245Avianca
Find Deal
Wed, Apr 2
12:32 am - 3:50 pmSFO-PTY
12h 18m2 stops
$559American Airlines
Find Deal
Fri, Feb 28
1:51 am - 10:46 amSFO-PTY
6h 55mnonstop
$732Copa Airlines
Find Deal
Wed, Mar 26
12:44 am - 10:46 amSFO-PTY
7h 02mnonstop
$736Copa Airlines
Find Deal
Sat, Feb 22
12:23 am - 1:29 pmSFO-PTY
10h 06m1 stop
$759American Airlines
Find Deal
Mon, Feb 10
6:40 pm - 2:45 pmSFO-PTY
17h 05m1 stop
$1,068United Airlines
Find Deal
Thu, Feb 20
5:00 am - 5:07 pmSFO-PTY
9h 07m1 stop
$1,193United Airlines
Find Deal
Tue, Jan 28
1:35 am - 9:00 pmSFO-PTY
16h 25m2 stops
9:55 pm - 12:00 pmPTY-SFO
17h 05m2 stops
$740Avianca
Find Deal
Sat, Jan 18 - Wed, Jan 22
1:35 am - 9:00 pmSFO-PTY
16h 25m2 stops
9:55 pm - 12:00 pmPTY-SFO
17h 05m2 stops
$758Avianca
Find Deal
Sat, Jan 18 - Wed, Jan 22
1:20 pm - 9:40 amSFO-PTY
17h 20m2 stops
9:55 pm - 12:00 pmPTY-SFO
17h 05m2 stops
$785Avianca
Find Deal
Sun, Jan 19 - Wed, Jan 22
1:35 am - 2:45 pmSFO-PTY
10h 10m1 stop
9:55 pm - 12:00 pmPTY-SFO
17h 05m2 stops
$807Avianca
Find Deal
Sat, Jan 18 - Wed, Jan 22
12:44 am - 10:46 amSFO-PTY
7h 02mnonstop
6:27 pm - 11:24 pmPTY-SFO
7h 57mnonstop
$1,149Copa Airlines
Find Deal
Sat, Jan 18 - Wed, Jan 22
12:44 am - 10:46 amSFO-PTY
7h 02mnonstop
12:38 pm - 5:33 pmPTY-SFO
7h 55mnonstop
$1,159Copa Airlines
Find Deal
Fri, Jan 17 - Sun, Jan 26
12:23 am - 1:29 pmSFO-PTY
10h 06m1 stop
2:35 pm - 11:07 pmPTY-SFO
11h 32m1 stop
$1,173American Airlines
Find Deal
Fri, Jan 17 - Sun, Jan 26
12:23 am - 1:29 pmSFO-PTY
10h 06m1 stop
2:35 pm - 11:04 amPTY-SFO
23h 29m2 stops
$1,178American Airlines
Find Deal
Fri, Jan 17 - Sun, Jan 26
3:00 pm - 10:25 amSFO-PTY
40h 25m3 stops
6:30 pm - 12:00 pmPTY-SFO
44h 30m2 stops
$1,222
Find Deal
Sat, Jan 18 - Sun, Jan 26
11:15 pm - 7:15 pmSFO-PTY
17h 00m3 stops
11:25 am - 12:39 pmPTY-SFO
28h 14m3 stops
$1,278
Find Deal
Sat, Jan 18 - Sun, Jan 26
7:20 pm - 5:13 amSFO-PTY
6h 53mnonstop
12:38 pm - 6:33 pmPTY-SFO
7h 55mnonstop
$649Copa Airlines
Find Deal
Thu, Mar 6 - Tue, Mar 11
1:37 am - 10:41 amSFO-PTY
7h 04mnonstop
5:50 pm - 11:40 pmPTY-SFO
7h 50mnonstop
$659Copa Airlines
Find Deal
Mon, Jun 23 - Mon, Jun 30
7:13 pm - 5:13 amSFO-PTY
7h 00mnonstop
6:27 pm - 11:24 pmPTY-SFO
7h 57mnonstop
$664Copa Airlines
Find Deal
Tue, Feb 18 - Fri, Feb 28
12:44 am - 10:46 amSFO-PTY
7h 02mnonstop
6:27 pm - 11:24 pmPTY-SFO
7h 57mnonstop
$674Copa Airlines
Find Deal
Mon, Feb 17 - Fri, Feb 28
1:37 am - 10:41 amSFO-PTY
7h 04mnonstop
5:50 pm - 11:40 pmPTY-SFO
7h 50mnonstop
$694Copa Airlines
Find Deal
Mon, Jun 30 - Sat, Jul 5
10:55 am - 8:10 pmSFO-PTY
7h 15mnonstop
3:15 pm - 8:58 pmPTY-SFO
7h 43mnonstop
$704United Airlines
Find Deal
Thu, Jun 19 - Tue, Jul 8
8:20 pm - 5:13 amSFO-PTY
6h 53mnonstop
12:38 pm - 6:30 pmPTY-SFO
7h 52mnonstop
$709Copa Airlines
Find Deal
Thu, Mar 27 - Thu, Apr 3
12:44 am - 10:46 amSFO-PTY
7h 02mnonstop
6:27 pm - 11:24 pmPTY-SFO
7h 57mnonstop
$716Copa Airlines
Find Deal
Tue, Feb 25 - Thu, Mar 6
1:51 am - 10:46 amSFO-PTY
6h 55mnonstop
5:43 pm - 11:40 pmPTY-SFO
7h 57mnonstop
$732Copa Airlines
Find Deal
Thu, Mar 13 - Thu, Mar 27
10:55 am - 8:10 pmSFO-PTY
7h 15mnonstop
3:15 pm - 8:58 pmPTY-SFO
7h 43mnonstop
$764United Airlines
Find Deal
Fri, Jun 20 - Mon, Jul 7

Avianca flights from San Francisco to Panama City

Our best Avianca deals on San Francisco to Panama City flight tickets
Avianca
Jan 26
SFO11:15 pmSan Francisco
10h 20m
2 stops
PTY12:35 pmPanama City Tocumen Intl
Mar 9
PTY1:30 pmPanama City Tocumen Intl
11h 25m
2 stops
SFO10:55 pmSan Francisco
Avianca
Feb 8
SFO1:20 pmSan Francisco
20h 15m
2 stops
PTY12:35 pmPanama City Tocumen Intl
Feb 18
PTY1:30 pmPanama City Tocumen Intl
11h 25m
2 stops
SFO9:55 pmSan Francisco
Avianca
Apr 30
SFO12:05 amSan Francisco
10h 30m
2 stops
PTY12:35 pmPanama City Tocumen Intl
May 5
PTY1:30 pmPanama City Tocumen Intl
11h 15m
2 stops
SFO10:45 pmSan Francisco

Copa Airlines flights from San Francisco to Panama City

Our best Copa Airlines deals on San Francisco to Panama City flight tickets
Copa Airlines
Feb 18
SFO7:13 pmSan Francisco
7h 00m
PTY5:13 amPanama City Tocumen Intl
Feb 28
PTY6:27 pmPanama City Tocumen Intl
7h 57m
SFO11:24 pmSan Francisco
Copa Airlines
Feb 17
SFO12:44 amSan Francisco
7h 02m
PTY10:46 amPanama City Tocumen Intl
Feb 28
PTY6:27 pmPanama City Tocumen Intl
7h 57m
SFO11:24 pmSan Francisco
Copa Airlines
Mar 27
SFO8:20 pmSan Francisco
6h 53m
PTY5:13 amPanama City Tocumen Intl
Apr 3
PTY12:38 pmPanama City Tocumen Intl
7h 52m
SFO6:30 pmSan Francisco

See travel insights to Panama City from

How to get the cheapest flight ticket from San Francisco to Panama City

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between San Francisco and Panama City?

What is the cheapest month to fly to Panama City?

In general, July is the cheapest month to fly from San Francisco to Panama City. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $577. If you’re not able to fly to Panama City in July, then September is your next best option. Flight prices from San Francisco to Panama City during September average around $597.

What is the cheapest day to depart on your flight to Panama City?

Our data shows that Tuesday is the least expensive day to fly to Panama City. Tickets to fly out on this day can be as low as $617. If your travel schedule is flexible, try to avoid departing on a Sunday because tickets tend to average around $692. These prices are subject to change though, so be sure to set up a Price Alert for flights to Panama City.

What is the cheapest time of day to depart on your flight to Panama City?

Our most recent data shows that the best time of day to fly to Panama City is at noon. Flights from San Francisco to Panama City during this time can be as low as $498. Try not to purchase tickets in the afternoon because they tend to be around $901. Of course, these prices can vary depending on the time of year and what airport you fly to.

What is the cheapest San Francisco to Panama City Tocumen Intl flight route?

Fly from San Francisco to Panama City Tocumen Intl for the best San Francisco - Panama City Tocumen Intl flight prices

How far in advance should I book a flight to Panama City?

You are more likely to see cheaper flights to Panama City from San Francisco when booking 10 weeks ahead of your departure date. In general, you can expect to find flights to Panama City for around $669 when searching 10 weeks out.However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama City from San Francisco for as low as $588 on momondo.

What cabin class options are available on San Francisco to Panama City Tocumen Intl flights?

There are 3 cabin classes available to choose from on San Francisco to Panama City Tocumen Intl flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

How have San Francisco to Panama City flight prices changed over time?

As of January 2025, prices for San Francisco to Panama City flights are approximately 34% more expensive when compared to flights at the same time last year.

When to book flights from San Francisco to Panama City

Are you open to changing your travel dates? Check out the ideal times to fly from San Francisco to Panama City according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap San Francisco to Panama City (SFO to PTY) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from San Francisco to Panama City

Best Price Found

$219

Fastest flight time

6h 53m

Direct flights

Mon, Tue, Wed, Fri, Sat and Sun

Airports in Panama City

1 airport
The best one-way flight to Panama City from San Francisco in the past 72 hours is $219. The best round-trip flight deal from San Francisco to Panama City found on momondo in the last 72 hours is $524.
The fastest flight from San Francisco to Panama City takes 6h 53m
Direct flights go from San Francisco to Panama City on Monday, Tuesday, Wednesday, Friday, Saturday and Sunday. Airlines offering direct flights are: United Airlines and Copa Airlines.
There is 1 airport near Panama City: Panama City Tocumen Intl (PTY)

  • How far is San Francisco to Panama City Tocumen Intl by plane?

    The distance between San Francisco and Panama City Tocumen Intl is about 3322.3 mi. A reasonable flight in good conditions will take 6h 53m.

  • When did momondo last update prices for flights from San Francisco Airport to Panama City Tocumen Intl Airport?

    Prices for flights from San Francisco Airport to Panama City Tocumen Intl Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from San Francisco Airport to Panama City Tocumen Intl Airport?

  • How old do you have to be to fly from San Francisco Airport to Panama City Tocumen Intl Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from San Francisco Airport to Panama City Tocumen Intl Airport.

  • What documentation or ID do you need to fly to Panama City Tocumen Intl Airport?

    The travel and health documents required for your trip to Panama City Tocumen Intl Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Panama City Tocumen Intl Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular plane model from San Francisco to Panama City?

  • What is the most popular airline from San Francisco to Panama City?


Best airlines flying from San Francisco to Panama City

Compare and see reviews for airlines that fly from San Francisco to Panama City with momondo
Airline
Rating
Free Cancellation
Price
AviancaPriceFrom $350Free CancellationRating
6.9
2,573 reviews
Search Avianca flights
Copa AirlinesPriceFrom $479Free CancellationRating
7.6
1,658 reviews
Search Copa Airlines flights
United AirlinesPriceFrom $537Free CancellationRating
7.4
8,965 reviews
Search United Airlines flights
DeltaPriceFrom $547Free CancellationRating
8.0
8,511 reviews
Search Delta flights
American AirlinesPriceFrom $560Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights
  • Copa Airlines Flights From San Francisco to Panama City

    Copa Airlines is one of the most popular airlines flying from San Francisco to Panama City, operating 7 flights/week on average for this route. A good Copa Airlines flight deal for San Francisco to Panama City starts from $479 round-trip, up to an average price of $646. Our users have rated Copa Airlines at 7.6/10.

  • United Airlines Flights From San Francisco to Panama City

    $537 is the best United Airlines flight deal from San Francisco to Panama City found on momondo over the last 72 hours. The average United Airlines ticket price found was closer to $735, however, with flight time and availability significantly affecting the price. United Airlines (7.4/10 from 8,964 user reviews) flies into Panama City from San Francisco 7 times in an average week so prices can vary.


Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
San Blas

Why use momondo?

Why should I use momondo to find a flight deal from San Francisco to Panama City?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from San Francisco to Panama City for you.

Can I find flights from San Francisco to Panama City with flexible booking policies on momondo?

Flights from San Francisco to Panama City with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from San Francisco to Panama City?

momondo provides multiple filters to help you find the best flight to Panama City from San Francisco. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from San Francisco to Panama City right now. Can momondo alert me if prices change?

Yes. momondo can track prices for San Francisco to Panama City flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.


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