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Cheap flights from San Diego to Santiago from $357

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from San Diego to Santiago departing on 5/5. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from San Diego to Santiago

Cheap round-trip flights

KAYAK's recommended round-trip deals from the most popular airlines that fly from San Diego to Santiago.
 Logo
6:15 am - 10:30 pmSAN-SCL
37h 15m3 stops
 Logo
3:35 am - 11:53 amSCL-SAN
35h 18m3 stops
Sat, May 17 - Thu, May 22
 Logo
6:15 am - 4:15 amSAN-SCL
43h 00m3 stops
 Logo
3:35 am - 11:53 amSCL-SAN
35h 18m2 stops
Sat, May 17 - Thu, May 22
Copa Airlines Logo
8:30 pm - 7:24 pmSAN-SCL
19h 54m2 stops
Copa Airlines Logo
4:11 am - 10:24 pmSCL-SAN
21h 13m2 stops
$928Copa Airlines
Find Deal
Tue, May 27 - Sun, Jun 1
Copa Airlines Logo
8:30 pm - 10:44 pmSAN-SCL
23h 14m2 stops
Copa Airlines Logo
12:13 am - 10:24 pmSCL-SAN
25h 11m2 stops
$956Copa Airlines
Find Deal
Sun, Jun 1 - Sat, Jun 7
American Airlines Logo
7:29 am - 6:55 amSAN-SCL
20h 26m2 stops
American Airlines Logo
9:55 pm - 9:44 pmSCL-SAN
26h 49m1 stop
$1,034American Airlines
Find Deal
Sun, Jun 1 - Sun, Jun 8
LATAM Airlines Logo
8:00 am - 7:00 amSAN-SCL
20h 00m1 stop
LATAM Airlines Logo
3:40 pm - 8:28 pmSCL-SAN
31h 48m2 stops
$1,041LATAM Airlines
Find Deal
Tue, May 27 - Sun, Jun 1
LATAM Airlines Logo
8:00 am - 7:00 amSAN-SCL
20h 00m1 stop
LATAM Airlines Logo
8:40 pm - 9:53 amSCL-SAN
16h 13m1 stop
$1,052LATAM Airlines
Find Deal
Tue, May 27 - Sun, Jun 1
Delta Logo
6:15 am - 7:35 amSAN-SCL
22h 20m2 stops
Delta Logo
8:40 pm - 9:53 amSCL-SAN
16h 13m1 stop
$1,104Delta
Find Deal
Sat, May 17 - Fri, May 23
Delta Logo
10:30 pm - 7:00 amSAN-SCL
29h 30m1 stop
Delta Logo
8:40 pm - 9:53 amSCL-SAN
16h 13m1 stop
$1,109Delta
Find Deal
Sat, May 17 - Fri, May 23
American Airlines Logo
9:20 am - 6:55 amSAN-SCL
18h 35m2 stops
American Airlines Logo
9:00 pm - 12:00 pmSCL-SAN
18h 00m2 stops
$1,161American Airlines
Find Deal
Thu, May 1 - Sat, May 17

American Airlines flights from San Diego to Santiago

Our best American Airlines deals on San Diego to Santiago flight tickets
American Airlines
Jun 1
SAN7:29 amSan Diego
20h 26m
2 stops
SCL6:55 amSantiago Arturo Merino Benitez
Jun 8
SCL9:55 pmSantiago Arturo Merino Benitez
26h 49m
1 stop
SAN9:44 pmSan Diego
American Airlines
May 1
SAN9:20 amSan Diego
18h 35m
2 stops
SCL6:55 amSantiago Arturo Merino Benitez
May 17
SCL9:00 pmSantiago Arturo Merino Benitez
18h 00m
2 stops
SAN12:00 pmSan Diego

Copa Airlines flights from San Diego to Santiago

Our best Copa Airlines deals on San Diego to Santiago flight tickets
Copa Airlines
May 27
SAN8:30 pmSan Diego
19h 54m
2 stops
SCL7:24 pmSantiago Arturo Merino Benitez
Jun 1
SCL4:11 amSantiago Arturo Merino Benitez
21h 13m
2 stops
SAN10:24 pmSan Diego
Copa Airlines
Jun 1
SAN8:30 pmSan Diego
23h 14m
2 stops
SCL10:44 pmSantiago Arturo Merino Benitez
Jun 7
SCL12:13 amSantiago Arturo Merino Benitez
25h 11m
2 stops
SAN10:24 pmSan Diego
Copa Airlines
May 5
SAN7:25 pmSan Diego
24h 19m
2 stops
SCL10:44 pmSantiago Arturo Merino Benitez
May 12
SCL12:13 amSantiago Arturo Merino Benitez
26h 46m
2 stops
SAN11:59 pmSan Diego

See travel insights to Santiago from

How to get the cheapest flight ticket from San Diego to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between San Diego and Santiago?

What is the cheapest month to fly to Santiago?

In general, September is the cheapest month to fly from San Diego to Santiago. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $843. If you don’t want to visit Santiago in September, then you should wait until March to fly from San Diego, when ticket prices are also cheap, with an average price of $927.

What is the cheapest day to depart on your flight to Santiago?

The cheapest day to depart on your flight to Santiago is on a Sunday when prices can be found for as low as $1,003. This is often the case because there is less demand to fly during this day of the week. Be sure to avoid booking your departure on a Tuesday as prices are generally higher than usual. According to our data, the average ticket price to Santiago on Tuesday is $1,131.

What is the cheapest time of day to depart on your flight to Santiago?

At noon is the cheapest time of day to fly from San Diego to Santiago when you can find flight prices for as low as $882. Flying to Santiago at noon is an ideal time because this is during off-peak travel hours. In the afternoon is when there is more demand to fly to Santiago, so prices are often more expensive at around $1,072 per ticket.

How far in advance should I book a flight to Santiago?

You are more likely to see cheaper flights to Santiago from San Diego when booking 25 weeks ahead of your departure date. In general, you can expect to find flights to Santiago for around $1,017 when searching 25 weeks out.However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santiago from San Diego for as low as $807 on momondo.

How have San Diego to Santiago flight prices changed over time?

As of April 2025, prices for San Diego to Santiago flights are approximately 23% more expensive when compared to flights at the same time last year.

When to book flights from San Diego to Santiago

Are you open to changing your travel dates? Check out the ideal times to fly from San Diego to Santiago according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap San Diego to Santiago (SAN to SCL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from San Diego to Santiago

Best Price Found

$357

Fastest flight time

15h 58m

Direct flights

None

Airports in Santiago

1 airport
The best one-way flight to Santiago from San Diego in the past 72 hours is $357. The best round-trip flight deal from San Diego to Santiago found on momondo in the last 72 hours is $906.
The fastest flight from San Diego to Santiago takes 15h 58m
There are no direct flights from San Diego to Santiago. Popular non-direct route for this connection is San Diego Airport - Santiago Arturo Merino Benitez Airport.
There is 1 airport near Santiago: Santiago Arturo Merino Benitez (SCL)

  • How far is San Diego to Santiago Arturo Merino Benitez by plane?

    There are 5476.6 mi between San Diego and Santiago Arturo Merino Benitez. In terms of flight time, this usually takes a little over 15h 58m.

  • When did momondo last update prices for flights from San Diego Airport to Santiago Arturo Merino Benitez Airport?

    Prices for flights from San Diego Airport to Santiago Arturo Merino Benitez Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from San Diego Airport to Santiago Arturo Merino Benitez Airport?

  • How old do you have to be to fly from San Diego Airport to Santiago Arturo Merino Benitez Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from San Diego Airport to Santiago Arturo Merino Benitez Airport.

  • What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

    The required travel and health documents for your Santiago Arturo Merino Benitez Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santiago Arturo Merino Benitez Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from San Diego to Santiago?


Best airlines flying from San Diego to Santiago

Compare and see reviews for airlines that fly from San Diego to Santiago with momondo
Airline
Rating
Free Cancellation
Price
Copa AirlinesPriceFrom $535Free CancellationRating
7.5
1,409 reviews
Search Copa Airlines flights
United AirlinesPriceFrom $542Free CancellationRating
7.4
8,667 reviews
Search United Airlines flights
DeltaPriceFrom $782Free CancellationRating
8.0
7,916 reviews
Search Delta flights
LATAM AirlinesPriceFrom $792Free CancellationRating
7.5
1,761 reviews
Search LATAM Airlines flights
American AirlinesPriceFrom $802Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights

Traveling to a place near Santiago?

Book flights to Santiago if you plan to visit one of these locations
Viña del Mar
Valparaíso
Santa Cruz
San Fernando
Valle Nevado
Pichilemu

Why use momondo?

Why should I use momondo to find a flight deal from San Diego to Santiago?

It is quick and easy to find San Diego to Santiago flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Santiago that suits you.

Can I find flights from San Diego to Santiago with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for San Diego to Santiago flights to just show those with flexible booking policies.

How can momondo help me find flights from San Diego to Santiago?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from San Diego to Santiago.

I’m not ready to book a flight from San Diego to Santiago right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Santiago, momondo offers a useful price alert feature which will track prices for flights to Santiago from San Diego and alert you when they change.


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