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Cheap flights from Panama City to Santo Domingo from $284

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Panama City to Santo Domingo departing on 5/5. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Panama City to Santo Domingo

Cheap round-trip flights

KAYAK's recommended round-trip deals from the most popular airlines that fly from Panama City to Santo Domingo.
Avianca Logo
3:25 am - 5:15 pmPTY-SDQ
12h 50m1 stop
Avianca Logo
6:10 pm - 10:10 amSDQ-PTY
17h 00m1 stop
$284Avianca
Find Deal
Mon, May 5 - Sun, May 11
Avianca Logo
3:20 am - 5:15 pmPTY-SDQ
12h 55m1 stop
Avianca Logo
11:45 am - 4:30 pmSDQ-PTY
5h 45m1 stop
$294Avianca
Find Deal
Tue, Apr 22 - Sat, Apr 26
Avianca Logo
3:20 am - 5:15 pmPTY-SDQ
12h 55m1 stop
Avianca Logo
11:45 am - 9:10 pmSDQ-PTY
10h 25m1 stop
$370Avianca
Find Deal
Thu, Apr 17 - Thu, Apr 24
 Logo
3:20 am - 5:15 pmPTY-SDQ
12h 55m1 stop
 Logo
6:54 am - 2:40 pmSDQ-PTY
32h 46m2 stops
Tue, Apr 22 - Sat, Apr 26
Copa Airlines Logo
6:36 pm - 10:03 pmPTY-SDQ
2h 27mnonstop
Copa Airlines Logo
11:51 am - 1:29 pmSDQ-PTY
2h 38mnonstop
$429Copa Airlines
Find Deal
Fri, Apr 18 - Thu, Apr 24
 Logo
1:30 pm - 2:00 amPTY-SDQ
11h 30m2 stops
 Logo
11:45 am - 4:30 pmSDQ-PTY
5h 45m1 stop
Wed, Apr 23 - Mon, Apr 28
Copa Airlines Logo
9:37 am - 1:09 pmPTY-SDQ
2h 32mnonstop
Copa Airlines Logo
6:17 pm - 7:55 pmSDQ-PTY
2h 38mnonstop
$479Copa Airlines
Find Deal
Sat, Apr 19 - Fri, Apr 25
American Airlines Logo
1:10 pm - 11:15 amPTY-SDQ
21h 05m1 stop
American Airlines Logo
5:00 am - 12:15 pmSDQ-PTY
8h 15m1 stop
$811American Airlines
Find Deal
Wed, Apr 16 - Sun, Apr 20
United Airlines Logo
7:55 am - 1:50 amPTY-SDQ
16h 55m2 stops
United Airlines Logo
1:10 pm - 6:37 pmSDQ-PTY
30h 27m2 stops
$1,301United Airlines
Find Deal
Tue, Apr 29 - Sat, May 31
United Airlines Logo
7:55 am - 1:50 amPTY-SDQ
16h 55m2 stops
United Airlines Logo
3:20 pm - 4:12 pmSDQ-PTY
25h 52m2 stops
$1,306United Airlines
Find Deal
Sat, May 3 - Wed, May 28

Avianca flights from Panama City to Santo Domingo

Our best Avianca deals on Panama City to Santo Domingo flight tickets
Avianca
May 5
PTY3:25 amPanama City Tocumen Intl
12h 50m
1 stop
SDQ5:15 pmSanto Domingo Las Americas
May 11
SDQ6:10 pmSanto Domingo Las Americas
17h 00m
1 stop
PTY10:10 amPanama City Tocumen Intl
Avianca
Apr 22
PTY3:20 amPanama City Tocumen Intl
12h 55m
1 stop
SDQ5:15 pmSanto Domingo Las Americas
Apr 26
SDQ11:45 amSanto Domingo Las Americas
5h 45m
1 stop
PTY4:30 pmPanama City Tocumen Intl
Avianca
Apr 17
PTY3:20 amPanama City Tocumen Intl
12h 55m
1 stop
SDQ5:15 pmSanto Domingo Las Americas
Apr 24
SDQ11:45 amSanto Domingo Las Americas
10h 25m
1 stop
PTY9:10 pmPanama City Tocumen Intl

United Airlines flights from Panama City to Santo Domingo

Our best United Airlines deals on Panama City to Santo Domingo flight tickets
United Airlines
Apr 29
PTY7:55 amPanama City Tocumen Intl
16h 55m
2 stops
SDQ1:50 amSanto Domingo Las Americas
May 31
SDQ1:10 pmSanto Domingo Las Americas
30h 27m
2 stops
PTY6:37 pmPanama City Tocumen Intl
United Airlines
May 3
PTY7:55 amPanama City Tocumen Intl
16h 55m
2 stops
SDQ1:50 amSanto Domingo Las Americas
May 28
SDQ3:20 pmSanto Domingo Las Americas
25h 52m
2 stops
PTY4:12 pmPanama City Tocumen Intl
United Airlines
Apr 29
PTY7:55 amPanama City Tocumen Intl
16h 55m
2 stops
SDQ1:50 amSanto Domingo Las Americas
May 6
SDQ1:10 pmSanto Domingo Las Americas
26h 04m
2 stops
PTY2:14 pmPanama City Tocumen Intl

See travel insights to Santo Domingo from

How to get the cheapest flight ticket from Panama City to Santo Domingo

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Santo Domingo?

If you don’t want to visit Santo Domingo in June, then you should wait until July to fly from Panama City, when ticket prices are also cheap, with an average price of $372.

What is the cheapest day to depart on your flight to Santo Domingo?

Our data shows that Thursday is the least expensive day to fly to Santo Domingo. Tickets to fly out on this day can be as low as $394. The most expensive day to fly to Santo Domingo is Sunday, with ticket prices averaging around $427.

What is the cheapest time of day to depart on your flight to Santo Domingo?

The cheapest time of day to fly to Santo Domingo is in the afternoon when flights can be purchased for as low as $395. Try not to purchase tickets in the morning because they tend to be around $417. Of course, these prices can vary depending on the time of year and what airport you fly to.

What is the cheapest Panama City Tocumen Intl to Santo Domingo Las Americas flight route?

Fly from Panama City Tocumen Intl to Santo Domingo Las Americas for the best Panama City Tocumen Intl - Santo Domingo Las Americas flight prices

How far in advance should I book a flight to Santo Domingo?

You are more likely to see cheaper flights to Santo Domingo from Panama City when booking 10 weeks ahead of your departure date. In general, you can expect to find flights to Santo Domingo for around $397 when searching 10 weeks out.However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santo Domingo from Panama City for as low as $393 on momondo.

What cabin class options are available on Panama City Tocumen Intl to Santo Domingo Las Americas flights?

There are 2 cabin classes available to choose from on Panama City Tocumen Intl to Santo Domingo Las Americas flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

How have Panama City to Santo Domingo flight prices changed over time?

As of April 2025, prices for Panama City to Santo Domingo flights are approximately 77% more expensive when compared to flights at the same time last year.

When to book flights from Panama City to Santo Domingo

Are you open to changing your travel dates? Check out the ideal times to fly from Panama City to Santo Domingo according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Panama City to Santo Domingo (PTY to SDQ) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama City to Santo Domingo

Best Price Found

$474

Fastest flight time

2h 27m

Direct flights

Fri, Sat and Sun

Airports in Santo Domingo

1 airport
The best one-way flight to Santo Domingo from Panama City in the past 72 hours is $474. The best round-trip flight deal from Panama City to Santo Domingo found on momondo in the last 72 hours is $284.
The fastest flight from Panama City to Santo Domingo takes 2h 27m
Direct flights go from Panama City to Santo Domingo on Friday, Saturday and Sunday. The only airline offering direct flights is Copa Airlines.
There is 1 airport near Santo Domingo: Santo Domingo Las Americas (SDQ)

  • How far is Panama City Tocumen Intl to Santo Domingo Las Americas by plane?

    The distance between Panama City Tocumen Intl and Santo Domingo Las Americas is about 918.3 mi. By plane, this route typically takes 2h 27m.

  • When did momondo last update prices for flights from Panama City Tocumen Intl Airport to Santo Domingo Las Americas Airport?

    Prices for flights from Panama City Tocumen Intl Airport to Santo Domingo Las Americas Airport are updated daily.

  • How many operators does momondo search for flights from Panama City Tocumen Intl Airport to Santo Domingo Las Americas Airport?

  • How old do you have to be to fly from Panama City Tocumen Intl Airport to Santo Domingo Las Americas Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Panama City Tocumen Intl Airport to Santo Domingo Las Americas Airport.

  • What documentation or ID do you need to fly to Santo Domingo Las Americas Airport?

    The travel and health documents required for your trip to Santo Domingo Las Americas Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Santo Domingo Las Americas Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular plane model from Panama City to Santo Domingo?

  • What is the most popular airline from Panama City to Santo Domingo?


Best airlines flying from Panama City to Santo Domingo

Compare and see reviews for airlines that fly from Panama City to Santo Domingo with momondo
Airline
Rating
Free Cancellation
Price
AviancaPriceFrom $280Free CancellationRating
6.7
2,304 reviews
Search Avianca flights
Copa AirlinesPriceFrom $345Free CancellationRating
7.6
1,400 reviews
Search Copa Airlines flights
  • Copa Airlines Flights From Panama City to Santo Domingo

    Copa Airlines operates around 21 flights from Panama City to Santo Domingo every week. The average price of these flights found in the last 72 hours has been $417, but momondo users have found Copa Airlines deals from Panama City to Santo Domingo from as low as $345 round-trip. Copa Airlines has been scored 7.6/10 in 1,400 reviews.


Traveling to a place near Santo Domingo?

Book flights to Santo Domingo if you plan to visit one of these locations
Juan Dolio

Why use momondo?

Why should I use momondo to find a flight deal from Panama City to Santo Domingo?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Panama City to Santo Domingo. momondo saves you time and could save you money on your trip.

Can I find flights from Panama City to Santo Domingo with flexible booking policies on momondo?

Flights from Panama City to Santo Domingo with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Panama City to Santo Domingo?

Once you have performed a search for Panama City to Santo Domingo flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Panama City to Santo Domingo right now. Can momondo alert me if prices change?

Price alerts on flights to Santo Domingo from Panama City are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.


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