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Cheap flights from Panama City to Santo Domingo from $221

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Panama City to Santo Domingo departing on 1/31. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Panama City to Santo Domingo

Cheap round-trip flights

These are some of the best round-trip flight deals from Panama City to Santo Domingo that have been recently found on momondo from popular airlines, departing in the coming months.

Cheap one-way flights

Flying one-way? These are some of the best deals recently discovered on momondo for flights from Panama City to Santo Domingo.

Cheap last minute flights

Planning a quick getaway from Panama City to Santo Domingo? These are the last-minute flight deals available now.

Cheap direct flights

If you prefer a non-stop journey, check out our latest direct flight deals to Santo Domingo, so you can enjoy a seamless trip without layovers.

Cheap bus & train deals from Panama City to Santo Domingo

Find recent round-trip train or bus tickets from Panama City to Santo Domingo.

All round-trip flight deals to Santo Domingo

The cheapest plane tickets to Santo Domingo found on KAYAK recently.
3:19 am - 5:20 pmPTY-SDQ
13h 01m1 stop
11:50 am - 9:00 pmSDQ-PTY
10h 10m1 stop
$398Avianca
Find Deal
Mon, Feb 3 - Tue, Mar 4
3:19 am - 10:55 amPTY-SDQ
6h 36m1 stop
11:50 am - 1:00 amSDQ-PTY
14h 10m1 stop
$399Avianca
Find Deal
Wed, Jan 15 - Thu, Jan 30
9:37 am - 1:05 pmPTY-SDQ
2h 28mnonstop
11:55 am - 1:30 pmSDQ-PTY
2h 35mnonstop
$418Copa Airlines
Find Deal
Wed, Feb 5 - Wed, Feb 19
7:18 am - 10:44 amPTY-SDQ
2h 26mnonstop
11:55 am - 1:30 pmSDQ-PTY
2h 35mnonstop
$425Copa Airlines
Find Deal
Mon, Jan 6 - Fri, Jan 10
3:19 am - 10:55 amPTY-SDQ
6h 36m1 stop
11:50 am - 4:30 pmSDQ-PTY
5h 40m1 stop
$426Avianca
Find Deal
Wed, Feb 19 - Mon, Mar 3
3:34 pm - 10:55 amPTY-SDQ
18h 21m2 stops
6:07 am - 9:00 pmSDQ-PTY
15h 53m2 stops
Fri, Jan 10 - Wed, Jan 15
3:19 am - 12:25 pmPTY-SDQ
8h 06m1 stop
6:15 pm - 12:20 amSDQ-PTY
7h 05m1 stop
Thu, Jan 9 - Wed, Jan 15
1:15 pm - 10:41 pmPTY-SDQ
8h 26m1 stop
5:00 am - 12:15 pmSDQ-PTY
8h 15m1 stop
$790American Airlines
Find Deal
Fri, Apr 11 - Fri, Apr 18
8:55 am - 2:49 amPTY-SDQ
16h 54m2 stops
2:55 pm - 5:07 pmSDQ-PTY
27h 12m2 stops
$1,154United Airlines
Find Deal
Sat, Jan 25 - Mon, Feb 3
11:35 am - 2:49 amPTY-SDQ
14h 14m2 stops
2:55 pm - 2:45 pmSDQ-PTY
24h 50m2 stops
$1,170United Airlines
Find Deal
Thu, Jan 30 - Thu, Feb 6
3:19 am - 10:55 amPTY-SDQ
6h 36m1 stop
$221Avianca
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Fri, Jan 31
9:55 pm - 5:20 pmPTY-SDQ
18h 25m1 stop
$248Avianca
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Thu, Mar 20
3:19 am - 11:05 pmPTY-SDQ
18h 46m2 stops
Mon, Feb 17
3:34 pm - 10:55 amPTY-SDQ
18h 21m2 stops
$288Avianca
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Fri, Feb 28
1:30 pm - 5:20 pmPTY-SDQ
26h 50m2 stops
$312Avianca
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Thu, Feb 20
11:20 am - 11:05 pmPTY-SDQ
10h 45m3 stops
Tue, Feb 18
6:36 pm - 10:06 pmPTY-SDQ
2h 30mnonstop
$468Copa Airlines
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Thu, Jan 2
12:52 pm - 4:23 pmPTY-SDQ
2h 31mnonstop
$548Copa Airlines
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Mon, Dec 30
4:40 pm - 2:49 amPTY-SDQ
33h 09m2 stops
$1,262United Airlines
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Thu, Jan 2
4:40 pm - 2:49 amPTY-SDQ
33h 09m2 stops
$1,469United Airlines
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Thu, Jan 2
3:19 am - 10:55 amPTY-SDQ
6h 36m1 stop
6:15 pm - 12:20 amSDQ-PTY
7h 05m1 stop
$563Avianca
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Sun, Dec 29 - Wed, Jan 22
3:19 am - 10:55 amPTY-SDQ
6h 36m1 stop
6:15 pm - 1:00 amSDQ-PTY
7h 45m1 stop
$597Avianca
Find Deal
Sun, Dec 29 - Thu, Jan 9
3:19 am - 10:55 amPTY-SDQ
6h 36m1 stop
6:07 am - 12:20 amSDQ-PTY
19h 13m2 stops
Sun, Dec 29 - Wed, Jan 22
6:30 pm - 10:55 amPTY-SDQ
15h 25m1 stop
6:15 pm - 12:20 amSDQ-PTY
7h 05m1 stop
$643Avianca
Find Deal
Fri, Dec 27 - Sun, Dec 29
3:19 am - 10:55 amPTY-SDQ
6h 36m1 stop
6:15 pm - 1:00 amSDQ-PTY
7h 45m1 stop
$647Avianca
Find Deal
Fri, Dec 27 - Thu, Jan 9
6:36 pm - 10:07 pmPTY-SDQ
2h 31mnonstop
11:55 am - 1:30 pmSDQ-PTY
2h 35mnonstop
$648Copa Airlines
Find Deal
Sat, Dec 28 - Thu, Jan 2
12:52 pm - 4:23 pmPTY-SDQ
2h 31mnonstop
11:53 am - 1:30 pmSDQ-PTY
2h 37mnonstop
$685Copa Airlines
Find Deal
Wed, Dec 25 - Tue, Dec 31
3:19 am - 8:39 pmPTY-SDQ
16h 20m2 stops
10:13 am - 12:20 amSDQ-PTY
15h 07m2 stops
Thu, Dec 26 - Sun, Dec 29
10:13 pm - 1:44 amPTY-SDQ
2h 31mnonstop
11:53 am - 1:30 pmSDQ-PTY
2h 37mnonstop
$728Copa Airlines
Find Deal
Fri, Dec 27 - Sun, Dec 29
7:18 am - 10:49 amPTY-SDQ
2h 31mnonstop
11:53 am - 1:30 pmSDQ-PTY
2h 37mnonstop
$766Copa Airlines
Find Deal
Wed, Dec 25 - Mon, Dec 30
6:36 pm - 10:06 pmPTY-SDQ
2h 30mnonstop
8:48 am - 10:30 amSDQ-PTY
2h 42mnonstop
$418Copa Airlines
Find Deal
Wed, Feb 5 - Mon, Feb 10
7:18 am - 10:44 amPTY-SDQ
2h 26mnonstop
11:55 am - 1:30 pmSDQ-PTY
2h 35mnonstop
$425Copa Airlines
Find Deal
Mon, Jan 6 - Fri, Jan 10
7:18 am - 10:44 amPTY-SDQ
2h 26mnonstop
6:38 pm - 8:15 pmSDQ-PTY
2h 37mnonstop
$461Copa Airlines
Find Deal
Tue, Feb 4 - Tue, Mar 4
7:18 am - 10:44 amPTY-SDQ
2h 26mnonstop
8:46 am - 10:30 amSDQ-PTY
2h 44mnonstop
$468Copa Airlines
Find Deal
Fri, Feb 28 - Tue, Mar 4
12:52 pm - 4:20 pmPTY-SDQ
2h 28mnonstop
6:18 am - 8:00 amSDQ-PTY
2h 42mnonstop
$503Copa Airlines
Find Deal
Sat, Jan 4 - Mon, Jan 27
7:18 am - 10:44 amPTY-SDQ
2h 26mnonstop
8:46 am - 10:30 amSDQ-PTY
2h 44mnonstop
$559Copa Airlines
Find Deal
Fri, Feb 28 - Wed, Mar 5
10:13 pm - 1:37 amPTY-SDQ
2h 24mnonstop
11:55 am - 1:30 pmSDQ-PTY
2h 35mnonstop
$685Copa Airlines
Find Deal
Fri, Jan 10 - Sat, Jan 11

Avianca flights from Panama City to Santo Domingo

Our best Avianca deals on Panama City to Santo Domingo flight tickets
Avianca
Feb 3
PTY3:19 amPanama City Tocumen Intl
13h 01m
1 stop
SDQ5:20 pmSanto Domingo Las Americas
Mar 4
SDQ11:50 amSanto Domingo Las Americas
10h 10m
1 stop
PTY9:00 pmPanama City Tocumen Intl
Avianca
Jan 15
PTY3:19 amPanama City Tocumen Intl
6h 36m
1 stop
SDQ10:55 amSanto Domingo Las Americas
Jan 30
SDQ11:50 amSanto Domingo Las Americas
14h 10m
1 stop
PTY1:00 amPanama City Tocumen Intl
Avianca
Feb 19
PTY3:19 amPanama City Tocumen Intl
6h 36m
1 stop
SDQ10:55 amSanto Domingo Las Americas
Mar 3
SDQ11:50 amSanto Domingo Las Americas
5h 40m
1 stop
PTY4:30 pmPanama City Tocumen Intl

United Airlines flights from Panama City to Santo Domingo

Our best United Airlines deals on Panama City to Santo Domingo flight tickets
United Airlines
Jan 25
PTY8:55 amPanama City Tocumen Intl
16h 54m
2 stops
SDQ2:49 amSanto Domingo Las Americas
Feb 3
SDQ2:55 pmSanto Domingo Las Americas
27h 12m
2 stops
PTY5:07 pmPanama City Tocumen Intl
United Airlines
Jan 30
PTY11:35 amPanama City Tocumen Intl
14h 14m
2 stops
SDQ2:49 amSanto Domingo Las Americas
Feb 6
SDQ2:55 pmSanto Domingo Las Americas
24h 50m
2 stops
PTY2:45 pmPanama City Tocumen Intl
United Airlines
Feb 1
PTY8:55 amPanama City Tocumen Intl
16h 54m
2 stops
SDQ2:49 amSanto Domingo Las Americas
Feb 20
SDQ2:55 pmSanto Domingo Las Americas
29h 43m
2 stops
PTY7:38 pmPanama City Tocumen Intl

See travel insights to Santo Domingo from

How to get the cheapest flight ticket from Panama City to Santo Domingo

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Panama City and Santo Domingo?

What is the cheapest month to fly to Santo Domingo?

If you don’t want to visit Santo Domingo in February, then you should wait until May to fly from Panama City, when ticket prices are also cheap, with an average price of $359.

What is the cheapest day to depart on your flight to Santo Domingo?

Our data shows that Wednesday is the least expensive day to fly to Santo Domingo. Tickets to fly out on this day can be as low as $372. The most expensive day to fly to Santo Domingo is Sunday, with ticket prices averaging around $401.

What is the cheapest time of day to depart on your flight to Santo Domingo?

The cheapest time of day to fly to Santo Domingo is in the evening when flights can be purchased for as low as $390. Try not to purchase tickets in the morning because they tend to be around $393. Of course, these prices can vary depending on the time of year and what airport you fly to.

What is the cheapest Panama City Tocumen Intl to Santo Domingo Las Americas flight route?

Fly from Panama City Tocumen Intl to Santo Domingo Las Americas for the best Panama City Tocumen Intl - Santo Domingo Las Americas flight prices

How far in advance should I book a flight to Santo Domingo?

The ideal time to book your flight to Santo Domingo is 57 days in advance when prices tend to average $381. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santo Domingo from Panama City for as low as $345 on momondo.

What cabin class options are available on Panama City Tocumen Intl to Santo Domingo Las Americas flights?

There are 2 cabin classes available to choose from on Panama City Tocumen Intl to Santo Domingo Las Americas flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Panama City to Santo Domingo flights?

You could potentially save up to 52% on your flight if you consider stops on a Panama City to Santo Domingo flight.

How have Panama City to Santo Domingo flight prices changed over time?

As of December 2024, prices for Panama City to Santo Domingo flights are approximately 26% more expensive when compared to flights at the same time last year.

When to book flights from Panama City to Santo Domingo

Are you open to changing your travel dates? Check out the ideal times to fly from Panama City to Santo Domingo according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Panama City to Santo Domingo (PTY to SDQ) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama City to Santo Domingo

Best Price Found

$221

Fastest flight time

2h 24m

Direct flights

Tue, Wed, Thu, Sat and Sun

Airports in Santo Domingo

1 airport
The best one-way flight to Santo Domingo from Panama City in the past 72 hours is $221. The best round-trip flight deal from Panama City to Santo Domingo found on momondo in the last 72 hours is $398.
The fastest flight from Panama City to Santo Domingo takes 2h 24m
Direct flights go from Panama City to Santo Domingo on Tuesday, Wednesday, Thursday, Saturday and Sunday. The only airline offering direct flights is Copa Airlines.
There is 1 airport near Santo Domingo: Santo Domingo Las Americas (SDQ)

  • How far is Panama City Tocumen Intl to Santo Domingo Las Americas by plane?

    The distance between Panama City Tocumen Intl and Santo Domingo Las Americas is about 918.3 mi. By plane, this route typically takes 2h 24m.

  • When did momondo last update prices for flights from Panama City Tocumen Intl Airport to Santo Domingo Las Americas Airport?

    Prices for flights from Panama City Tocumen Intl Airport to Santo Domingo Las Americas Airport are updated daily.

  • How many operators does momondo search for flights from Panama City Tocumen Intl Airport to Santo Domingo Las Americas Airport?

  • How old do you have to be to fly from Panama City Tocumen Intl Airport to Santo Domingo Las Americas Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Panama City Tocumen Intl Airport to Santo Domingo Las Americas Airport.

  • What documentation or ID do you need to fly to Santo Domingo Las Americas Airport?

    The travel and health documents required for your trip to Santo Domingo Las Americas Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Santo Domingo Las Americas Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular plane model from Panama City to Santo Domingo?

  • What is the most popular airline from Panama City to Santo Domingo?


Best airlines flying from Panama City to Santo Domingo

Compare and see reviews for airlines that fly from Panama City to Santo Domingo with momondo
Airline
Rating
Free Cancellation
Price
AviancaPriceFrom $262Free CancellationRating
7.0
2,639 reviews
Search Avianca flights
Copa AirlinesPriceFrom $345Free CancellationRating
7.7
1,712 reviews
Search Copa Airlines flights
  • Copa Airlines Flights From Panama City to Santo Domingo

    Copa Airlines operates around 17 flights from Panama City to Santo Domingo every week. The average price of these flights found in the last 72 hours has been $393, but momondo users have found Copa Airlines deals from Panama City to Santo Domingo from as low as $345 round-trip. Copa Airlines has been scored 7.7/10 in 1,710 reviews.


Why use momondo?

Why should I use momondo to find a flight deal from Panama City to Santo Domingo?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Panama City to Santo Domingo. momondo saves you time and could save you money on your trip.

Can I find flights from Panama City to Santo Domingo with flexible booking policies on momondo?

Flights from Panama City to Santo Domingo with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Panama City to Santo Domingo?

Once you have performed a search for Panama City to Santo Domingo flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Panama City to Santo Domingo right now. Can momondo alert me if prices change?

Price alerts on flights to Santo Domingo from Panama City are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.


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