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Cheap flights from Mexico City to Santiago from $291

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Mexico City to Santiago departing on 1/15. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Mexico City to Santiago

Cheap round-trip flights

These are some of the best round-trip flight deals from Mexico City to Santiago that have been recently found on momondo from popular airlines, departing in the coming months.

Cheap one-way flights

Flying one-way? These are some of the best deals recently discovered on momondo for flights from Mexico City to Santiago.

Cheap last minute flights

Planning a quick getaway from Mexico City to Santiago? These are the last-minute flight deals available now.

Cheap direct flights

If you prefer a non-stop journey, check out our latest direct flight deals to Santiago, so you can enjoy a seamless trip without layovers.

Cheap bus & train deals from Mexico City to Santiago

Find recent round-trip train or bus tickets from Mexico City to Santiago.

All round-trip flight deals to Santiago

The cheapest plane tickets to Santiago found on KAYAK recently.
8:20 pm - 6:25 amMEX-SCL
8h 05mnonstop
4:15 am - 1:50 pmSCL-MEX
11h 35m1 stop
$476LATAM Airlines
Find Deal
Tue, Apr 15 - Tue, May 13
4:05 pm - 6:25 amMEX-SCL
11h 20m1 stop
8:55 pm - 1:50 pmSCL-MEX
19h 55m1 stop
$502LATAM Airlines
Find Deal
Mon, Mar 17 - Sat, Mar 29
11:15 pm - 2:20 pmMEX-SCL
12h 05m1 stop
3:25 pm - 3:00 amSCL-MEX
14h 35m1 stop
$508Avianca
Find Deal
Mon, Mar 10 - Mon, Mar 24
2:00 pm - 4:10 amMEX-SCL
12h 10m1 stop
2:30 pm - 3:05 amSCL-MEX
14h 35m1 stop
$509Avianca
Find Deal
Fri, May 9 - Thu, May 29
2:00 am - 12:13 amMEX-SCL
19h 13m1 stop
3:32 am - 10:00 pmSCL-MEX
21h 28m1 stop
$521Copa Airlines
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Wed, Mar 19 - Wed, Mar 26
2:00 am - 12:13 amMEX-SCL
19h 13m1 stop
12:28 pm - 10:00 pmSCL-MEX
12h 32m1 stop
$547Copa Airlines
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Thu, Mar 13 - Thu, Mar 27
9:45 pm - 2:40 pmMEX-SCL
13h 55m1 stop
11:05 pm - 11:00 amSCL-MEX
14h 55m1 stop
Wed, Feb 5 - Tue, Feb 18
9:45 pm - 2:40 pmMEX-SCL
13h 55m1 stop
11:05 pm - 11:00 amSCL-MEX
14h 55m1 stop
Tue, Feb 4 - Sun, Feb 23
10:10 am - 9:15 pmMEX-SCL
8h 05mnonstop
11:15 pm - 4:45 amSCL-MEX
8h 30mnonstop
$762Aeromexico
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Sun, Mar 16 - Tue, Mar 25
10:10 am - 9:15 pmMEX-SCL
8h 05mnonstop
11:15 pm - 4:45 amSCL-MEX
8h 30mnonstop
$788Aeromexico
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Fri, Mar 7 - Sun, Mar 23
9:45 pm - 10:15 pmMEX-SCL
21h 30m1 stop
Wed, Jan 15
9:45 pm - 9:55 pmMEX-SCL
21h 10m1 stop
Tue, Jan 21
11:15 pm - 2:20 pmMEX-SCL
12h 05m1 stop
$356Avianca
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Fri, Mar 7
11:15 pm - 2:20 pmMEX-SCL
12h 05m1 stop
$361Avianca
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Wed, Jan 29
1:20 am - 12:13 amMEX-SCL
19h 53m1 stop
$560Copa Airlines
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Sat, Jan 11
7:50 pm - 7:00 amMEX-SCL
8h 10mnonstop
$563LATAM Airlines
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Fri, Jan 31
7:50 pm - 7:00 amMEX-SCL
8h 10mnonstop
$572LATAM Airlines
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Sat, Feb 1
10:05 am - 9:15 pmMEX-SCL
8h 10mnonstop
$598Aeromexico
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Wed, Jan 15
10:05 am - 9:10 pmMEX-SCL
8h 05mnonstop
$650Aeromexico
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Sat, Feb 22
9:25 am - 3:25 amMEX-SCL
15h 00m1 stop
$830Copa Airlines
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Thu, Jan 9
1:20 am - 12:13 amMEX-SCL
19h 53m1 stop
3:32 am - 10:05 pmSCL-MEX
21h 33m1 stop
$693Copa Airlines
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Tue, Jan 7 - Wed, Mar 19
1:20 am - 8:19 pmMEX-SCL
15h 59m1 stop
5:32 am - 1:00 amSCL-MEX
22h 28m1 stop
$723Copa Airlines
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Mon, Jan 6 - Tue, Jan 21
11:15 pm - 2:20 pmMEX-SCL
12h 05m1 stop
12:45 am - 12:10 pmSCL-MEX
14h 25m1 stop
$817Avianca
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Mon, Jan 6 - Thu, Jan 16
5:00 am - 11:40 pmMEX-SCL
15h 40m2 stops
12:45 am - 12:10 pmSCL-MEX
14h 25m1 stop
$884Avianca
Find Deal
Mon, Jan 6 - Thu, Jan 16
8:00 am - 5:25 amMEX-SCL
18h 25m1 stop
9:10 am - 2:50 pmSCL-MEX
8h 40mnonstop
$915LATAM Airlines
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Mon, Jan 6 - Fri, Jan 17
7:50 pm - 7:00 amMEX-SCL
8h 10mnonstop
9:10 am - 2:50 pmSCL-MEX
8h 40mnonstop
$999LATAM Airlines
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Mon, Jan 6 - Fri, Jan 17
10:35 pm - 5:50 amMEX-SCL
28h 15m3 stops
3:25 pm - 12:10 pmSCL-MEX
23h 45m1 stop
$1,265
Find Deal
Fri, Jan 3 - Sun, Jan 5
10:10 am - 9:20 pmMEX-SCL
8h 10mnonstop
11:20 pm - 4:51 amSCL-MEX
8h 31mnonstop
$1,367Aeromexico
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Tue, Jan 7 - Sun, Jan 19
7:50 pm - 7:00 amMEX-SCL
8h 10mnonstop
12:45 am - 12:10 pmSCL-MEX
14h 25m1 stop
$1,492
Find Deal
Fri, Jan 3 - Sat, Jan 4
10:10 am - 9:20 pmMEX-SCL
8h 10mnonstop
11:20 pm - 4:51 amSCL-MEX
8h 31mnonstop
$1,695Aeromexico
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Tue, Jan 7 - Mon, Jan 20
8:20 pm - 6:25 amMEX-SCL
8h 05mnonstop
8:10 am - 2:55 pmSCL-MEX
8h 45mnonstop
$476LATAM Airlines
Find Deal
Fri, May 9 - Thu, May 29
7:50 pm - 7:00 amMEX-SCL
8h 10mnonstop
9:10 am - 2:50 pmSCL-MEX
8h 40mnonstop
$502LATAM Airlines
Find Deal
Mon, Mar 17 - Sat, Mar 29
8:20 pm - 7:25 amMEX-SCL
8h 05mnonstop
8:10 am - 2:55 pmSCL-MEX
8h 45mnonstop
$580LATAM Airlines
Find Deal
Fri, Apr 4 - Sat, Apr 19
8:20 pm - 6:25 amMEX-SCL
8h 05mnonstop
8:10 am - 2:55 pmSCL-MEX
8h 45mnonstop
$612LATAM Airlines
Find Deal
Tue, Apr 15 - Tue, Apr 22
7:50 pm - 7:00 amMEX-SCL
8h 10mnonstop
9:10 am - 2:50 pmSCL-MEX
8h 40mnonstop
$694LATAM Airlines
Find Deal
Tue, Jan 28 - Tue, Feb 18
7:50 pm - 7:00 amMEX-SCL
8h 10mnonstop
9:10 am - 2:50 pmSCL-MEX
8h 40mnonstop
$735LATAM Airlines
Find Deal
Sun, Jan 26 - Tue, Feb 18
7:50 pm - 7:00 amMEX-SCL
8h 10mnonstop
9:10 am - 2:50 pmSCL-MEX
8h 40mnonstop
$737LATAM Airlines
Find Deal
Tue, Jan 28 - Fri, Feb 21
7:50 pm - 7:00 amMEX-SCL
8h 10mnonstop
9:10 am - 2:50 pmSCL-MEX
8h 40mnonstop
$740LATAM Airlines
Find Deal
Tue, Feb 4 - Sun, Feb 23
10:10 am - 9:15 pmMEX-SCL
8h 05mnonstop
11:15 pm - 4:45 amSCL-MEX
8h 30mnonstop
$762Aeromexico
Find Deal
Tue, Mar 4 - Tue, Mar 18
10:10 am - 9:15 pmMEX-SCL
8h 05mnonstop
11:15 pm - 4:45 amSCL-MEX
8h 30mnonstop
$788Aeromexico
Find Deal
Fri, Mar 7 - Sun, Mar 23

LATAM Airlines flights from Mexico City to Santiago

Our best LATAM Airlines deals on Mexico City to Santiago flight tickets
LATAM Airlines
Apr 15
MEX8:20 pmMexico City Benito Juarez
8h 05m
SCL6:25 amSantiago Arturo Merino Benitez
May 13
SCL4:15 amSantiago Arturo Merino Benitez
11h 35m
1 stop
MEX1:50 pmMexico City Benito Juarez
LATAM Airlines
Mar 17
MEX4:05 pmMexico City Benito Juarez
11h 20m
1 stop
SCL6:25 amSantiago Arturo Merino Benitez
Mar 29
SCL8:55 pmSantiago Arturo Merino Benitez
19h 55m
1 stop
MEX1:50 pmMexico City Benito Juarez
LATAM Airlines
Apr 15
MEX3:20 pmMexico City Benito Juarez
19h 35m
2 stops
SCL12:55 pmSantiago Arturo Merino Benitez
May 13
SCL4:15 amSantiago Arturo Merino Benitez
11h 35m
1 stop
MEX1:50 pmMexico City Benito Juarez

Avianca flights from Mexico City to Santiago

Our best Avianca deals on Mexico City to Santiago flight tickets
Avianca
Mar 10
MEX11:15 pmMexico City Benito Juarez
12h 05m
1 stop
SCL2:20 pmSantiago Arturo Merino Benitez
Mar 24
SCL3:25 pmSantiago Arturo Merino Benitez
14h 35m
1 stop
MEX3:00 amMexico City Benito Juarez
Avianca
May 9
MEX2:00 pmMexico City Benito Juarez
12h 10m
1 stop
SCL4:10 amSantiago Arturo Merino Benitez
May 29
SCL2:30 pmSantiago Arturo Merino Benitez
14h 35m
1 stop
MEX3:05 amMexico City Benito Juarez
Avianca
Mar 11
MEX11:15 pmMexico City Benito Juarez
12h 05m
1 stop
SCL2:20 pmSantiago Arturo Merino Benitez
Mar 18
SCL6:55 amSantiago Arturo Merino Benitez
14h 15m
1 stop
MEX6:10 pmMexico City Benito Juarez

See travel insights to Santiago from

How to get the cheapest flight ticket from Mexico City to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Santiago?

In general, August is the cheapest month to fly from Mexico City to Santiago. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $560. If you don’t want to visit Santiago in August, then you should wait until March to fly from Mexico City, when ticket prices are also cheap, with an average price of $578.

What is the cheapest day to depart on your flight to Santiago?

The cheapest day to depart on your flight to Santiago is on a Thursday when prices can be found for as low as $608. This is often the case because there is less demand to fly during this day of the week. Be sure to avoid booking your departure on a Saturday as prices are generally higher than usual. According to our data, the average ticket price to Santiago on Saturday is $787.

What is the cheapest time of day to depart on your flight to Santiago?

At noon is the cheapest time of day to fly from Mexico City to Santiago when you can find flight prices for as low as $592. Flying to Santiago at noon is an ideal time because this is during off-peak travel hours. In the afternoon is when there is more demand to fly to Santiago, so prices are often more expensive at around $770 per ticket.

What is the cheapest Mexico City Benito Juarez to Santiago Arturo Merino Benitez flight route?

Fly from Mexico City Benito Juarez to Santiago Arturo Merino Benitez for the best Mexico City Benito Juarez - Santiago Arturo Merino Benitez flight prices

How far in advance should I book a flight to Santiago?

Most flyers found that booking tickets 60 days in advance of their planned departure date is the best time to get cheap flights to Santiago. During this timeframe, flight prices are around $629. Don’t hesitate to check prices now though because momondo users recently found tickets for as low as $518.

What cabin class options are available on Mexico City Benito Juarez to Santiago Arturo Merino Benitez flights?

There are 3 cabin classes available to choose from on Mexico City Benito Juarez to Santiago Arturo Merino Benitez flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Mexico City to Santiago flights?

You could potentially save up to 44% on your flight if you consider stops on a Mexico City to Santiago flight.

How have Mexico City to Santiago flight prices changed over time?

As of January 2025, prices for Mexico City to Santiago flights are approximately 2% more expensive when compared to flights at the same time last year.

When to book flights from Mexico City to Santiago

Are you open to changing your travel dates? Check out the ideal times to fly from Mexico City to Santiago according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Mexico City to Santiago (MEX to SCL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Mexico City to Santiago

Best Price Found

$291

Fastest flight time

8h 05m

Direct flights

Every day

Airports in Santiago

1 airport
The best one-way flight to Santiago from Mexico City in the past 72 hours is $291. The best round-trip flight deal from Mexico City to Santiago found on momondo in the last 72 hours is $476.
The fastest flight from Mexico City to Santiago takes 8h 05m
Direct flights go from Mexico City to Santiago every day.
There is 1 airport near Santiago: Santiago Arturo Merino Benitez (SCL)

  • How far is Mexico City Benito Juarez to Santiago Arturo Merino Benitez by plane?

    The straight-line distance from Mexico City Benito Juarez to Santiago Arturo Merino Benitez is 4104.7 mi. In terms of flight time, this usually takes a little over 8h 05m.

  • When did momondo last update prices for flights from Mexico City Benito Juarez Airport to Santiago Arturo Merino Benitez Airport?

    Prices for flights from Mexico City Benito Juarez Airport to Santiago Arturo Merino Benitez Airport were last updated today.

  • How many operators does momondo search for flights from Mexico City Benito Juarez Airport to Santiago Arturo Merino Benitez Airport?

  • How old do you have to be to fly from Mexico City Benito Juarez Airport to Santiago Arturo Merino Benitez Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Mexico City Benito Juarez Airport to Santiago Arturo Merino Benitez Airport.

  • What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

    The required travel and health documents for your Santiago Arturo Merino Benitez Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santiago Arturo Merino Benitez Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular plane model from Mexico City to Santiago?

  • What is the most popular airline from Mexico City to Santiago?


Best airlines flying from Mexico City to Santiago

Compare and see reviews for airlines that fly from Mexico City to Santiago with momondo
Airline
Rating
Free Cancellation
Price
AeromexicoPriceFrom $342Free CancellationRating
7.5
1,878 reviews
Search Aeromexico flights
AviancaPriceFrom $364Free CancellationRating
6.9
2,594 reviews
Search Avianca flights
Copa AirlinesPriceFrom $508Free CancellationRating
7.6
1,670 reviews
Search Copa Airlines flights
LATAM AirlinesPriceFrom $520Free CancellationRating
7.5
1,851 reviews
Search LATAM Airlines flights
  • Aeromexico Flights From Mexico City to Santiago

    Aeromexico flies from Mexico City to Santiago around 2 times per week, with 1,878 momondo users rating the airline 7.5/10. The cheapest Aeromexico deal from Mexico City to Santiago in the last 72 hours was $342 (round-trip), much lower than the average airfare cost of $640 for Aeromexico flights on this route.

  • LATAM Airlines Flights From Mexico City to Santiago

    LATAM Airlines is also a popular choice for this route. LATAM Airlines flight deals for Mexico City to Santiago start from as low as $520 round-trip, depending on your selected dates, with average LATAM Airlines deals seen on momondo around $697. LATAM Airlines operates 7 flights to Santiago from Mexico City in an average week. Users have rated it 7.5/10 across 1,851 reviews.


Why use momondo?

Why should I use momondo to find a flight deal from Mexico City to Santiago?

Finding the right flight to Santiago from Mexico City is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Santiago quick and easy, saving you time and money.

Can I find flights from Mexico City to Santiago with flexible booking policies on momondo?

All flight searches from Mexico City to Santiago on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Mexico City to Santiago?

momondo provides multiple filters to help you find the best flight to Santiago from Mexico City. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Mexico City to Santiago right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Mexico City to Santiago flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.


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