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Cheap flights from Mexico City to Santiago from $235

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Mexico City to Santiago departing on 4/6. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Mexico City to Santiago

Cheap round-trip flights

KAYAK's recommended round-trip deals from the most popular airlines that fly from Mexico City to Santiago.
4:55 am - 10:30 pmMEX-SCL
15h 35m1 stop
2:30 pm - 3:05 amSCL-MEX
14h 35m1 stop
$453Avianca
Find Deal
Thu, Apr 17 - Wed, May 21
1:40 am - 11:11 pmMEX-SCL
19h 31m1 stop
11:34 am - 10:00 pmSCL-MEX
12h 26m1 stop
$459Copa Airlines
Find Deal
Tue, Apr 8 - Wed, Apr 16
4:55 am - 10:30 pmMEX-SCL
15h 35m1 stop
2:30 pm - 3:05 amSCL-MEX
14h 35m1 stop
$460Avianca
Find Deal
Mon, Apr 7 - Fri, Apr 18
12:40 am - 10:30 pmMEX-SCL
19h 50m1 stop
11:55 pm - 11:00 pmSCL-MEX
25h 05m1 stop
$461Avianca
Find Deal
Thu, May 8 - Fri, May 16
1:05 pm - 2:47 amMEX-SCL
11h 42m1 stop
11:34 am - 10:05 pmSCL-MEX
12h 31m1 stop
$470Copa Airlines
Find Deal
Tue, Apr 8 - Thu, Apr 17
1:40 am - 11:11 pmMEX-SCL
19h 31m1 stop
11:34 am - 12:15 amSCL-MEX
14h 41m1 stop
$474Copa Airlines
Find Deal
Mon, Apr 7 - Thu, Apr 17
2:00 am - 11:08 pmMEX-SCL
19h 08m1 stop
4:10 am - 12:15 amSCL-MEX
22h 05m1 stop
$482Copa Airlines
Find Deal
Thu, Jun 26 - Mon, Jul 21
11:20 pm - 1:25 pmMEX-SCL
12h 05m1 stop
11:55 pm - 3:25 pmSCL-MEX
17h 30m2 stops
$484Avianca
Find Deal
Thu, Apr 17 - Wed, May 21
3:10 pm - 3:30 amMEX-SCL
10h 20m1 stop
8:20 am - 2:55 pmSCL-MEX
8h 35mnonstop
$619LATAM Airlines
Find Deal
Fri, Jun 27 - Mon, Jul 21
8:20 pm - 6:40 amMEX-SCL
8h 20mnonstop
8:20 am - 2:55 pmSCL-MEX
8h 35mnonstop
$641LATAM Airlines
Find Deal
Fri, Jun 27 - Mon, Jul 21

Copa Airlines flights from Mexico City to Santiago

Our best Copa Airlines deals on Mexico City to Santiago flight tickets
Copa Airlines
Apr 8
MEX1:40 amMexico City Benito Juarez
19h 31m
1 stop
SCL11:11 pmSantiago Arturo Merino Benitez
Apr 16
SCL11:34 amSantiago Arturo Merino Benitez
12h 26m
1 stop
MEX10:00 pmMexico City Benito Juarez
Copa Airlines
Apr 8
MEX1:05 pmMexico City Benito Juarez
11h 42m
1 stop
SCL2:47 amSantiago Arturo Merino Benitez
Apr 17
SCL11:34 amSantiago Arturo Merino Benitez
12h 31m
1 stop
MEX10:05 pmMexico City Benito Juarez
Copa Airlines
Apr 7
MEX1:40 amMexico City Benito Juarez
19h 31m
1 stop
SCL11:11 pmSantiago Arturo Merino Benitez
Apr 17
SCL11:34 amSantiago Arturo Merino Benitez
14h 41m
1 stop
MEX12:15 amMexico City Benito Juarez

Avianca flights from Mexico City to Santiago

Our best Avianca deals on Mexico City to Santiago flight tickets
Avianca
Apr 17
MEX4:55 amMexico City Benito Juarez
15h 35m
1 stop
SCL10:30 pmSantiago Arturo Merino Benitez
May 21
SCL2:30 pmSantiago Arturo Merino Benitez
14h 35m
1 stop
MEX3:05 amMexico City Benito Juarez
Avianca
Apr 7
MEX4:55 amMexico City Benito Juarez
15h 35m
1 stop
SCL10:30 pmSantiago Arturo Merino Benitez
Apr 18
SCL2:30 pmSantiago Arturo Merino Benitez
14h 35m
1 stop
MEX3:05 amMexico City Benito Juarez
Avianca
May 8
MEX12:40 amMexico City Benito Juarez
19h 50m
1 stop
SCL10:30 pmSantiago Arturo Merino Benitez
May 16
SCL11:55 pmSantiago Arturo Merino Benitez
25h 05m
1 stop
MEX11:00 pmMexico City Benito Juarez

See travel insights to Santiago from

How to get the cheapest flight ticket from Mexico City to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Mexico City and Santiago?

What is the cheapest month to fly to Santiago?

In general, August is the cheapest month to fly from Mexico City to Santiago. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $572. If you don’t want to visit Santiago in August, then you should wait until May to fly from Mexico City, when ticket prices are also cheap, with an average price of $586.

What is the cheapest day to depart on your flight to Santiago?

The cheapest day to depart on your flight to Santiago is on a Sunday when prices can be found for as low as $629. This is often the case because there is less demand to fly during this day of the week. Be sure to avoid booking your departure on a Friday as prices are generally higher than usual. According to our data, the average ticket price to Santiago on Friday is $1,033.

What is the cheapest time of day to depart on your flight to Santiago?

At noon is the cheapest time of day to fly from Mexico City to Santiago when you can find flight prices for as low as $592. Flying to Santiago at noon is an ideal time because this is during off-peak travel hours. In the evening is when there is more demand to fly to Santiago, so prices are often more expensive at around $799 per ticket.

What is the cheapest Mexico City Benito Juarez to Santiago Arturo Merino Benitez flight route?

Fly from Mexico City Benito Juarez to Santiago Arturo Merino Benitez for the best Mexico City Benito Juarez - Santiago Arturo Merino Benitez flight prices

How far in advance should I book a flight to Santiago?

You are more likely to see cheaper flights to Santiago from Mexico City when booking 11 weeks ahead of your departure date. In general, you can expect to find flights to Santiago for around $631 when searching 11 weeks out.However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santiago from Mexico City for as low as $560 on momondo.

What cabin class options are available on Mexico City Benito Juarez to Santiago Arturo Merino Benitez flights?

There are 3 cabin classes available to choose from on Mexico City Benito Juarez to Santiago Arturo Merino Benitez flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

How have Mexico City to Santiago flight prices changed over time?

As of March 2025, prices for Mexico City to Santiago flights are approximately 6% more expensive when compared to flights at the same time last year.

When to book flights from Mexico City to Santiago

Are you open to changing your travel dates? Check out the ideal times to fly from Mexico City to Santiago according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Mexico City to Santiago (MEX to SCL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Mexico City to Santiago

Best Price Found

$235

Fastest flight time

8h 05m

Direct flights

Every day

Airports in Santiago

1 airport
The best one-way flight to Santiago from Mexico City in the past 72 hours is $235. The best round-trip flight deal from Mexico City to Santiago found on momondo in the last 72 hours is $453.
The fastest flight from Mexico City to Santiago takes 8h 05m
Direct flights go from Mexico City to Santiago every day.
There is 1 airport near Santiago: Santiago Arturo Merino Benitez (SCL)

  • How far is Mexico City Benito Juarez to Santiago Arturo Merino Benitez by plane?

    The straight-line distance from Mexico City Benito Juarez to Santiago Arturo Merino Benitez is 4104.7 mi. In terms of flight time, this usually takes a little over 8h 05m.

  • When did momondo last update prices for flights from Mexico City Benito Juarez Airport to Santiago Arturo Merino Benitez Airport?

    Prices for flights from Mexico City Benito Juarez Airport to Santiago Arturo Merino Benitez Airport were last updated today.

  • How many operators does momondo search for flights from Mexico City Benito Juarez Airport to Santiago Arturo Merino Benitez Airport?

  • How old do you have to be to fly from Mexico City Benito Juarez Airport to Santiago Arturo Merino Benitez Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Mexico City Benito Juarez Airport to Santiago Arturo Merino Benitez Airport.

  • What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

    The required travel and health documents for your Santiago Arturo Merino Benitez Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santiago Arturo Merino Benitez Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular plane model from Mexico City to Santiago?

  • What is the most popular airline from Mexico City to Santiago?


Best airlines flying from Mexico City to Santiago

Compare and see reviews for airlines that fly from Mexico City to Santiago with momondo
Airline
Rating
Free Cancellation
Price
AeromexicoPriceFrom $342Free CancellationRating
7.4
1,701 reviews
Search Aeromexico flights
Copa AirlinesPriceFrom $347Free CancellationRating
7.5
1,395 reviews
Search Copa Airlines flights
AviancaPriceFrom $364Free CancellationRating
6.7
2,300 reviews
Search Avianca flights
LATAM AirlinesPriceFrom $510Free CancellationRating
7.5
1,750 reviews
Search LATAM Airlines flights
  • LATAM Airlines Flights From Mexico City to Santiago

    LATAM Airlines flies from Mexico City to Santiago around 3 times per week, with 1,750 momondo users rating the airline 7.5/10. The cheapest LATAM Airlines deal from Mexico City to Santiago in the last 72 hours was $510 (round-trip), much lower than the average airfare cost of $679 for LATAM Airlines flights on this route.

  • Aeromexico Flights From Mexico City to Santiago

    Aeromexico is also a popular choice for this route. Aeromexico flight deals for Mexico City to Santiago start from as low as $342 round-trip, depending on your selected dates, with average Aeromexico deals seen on momondo around $689. Aeromexico operates 2 flights to Santiago from Mexico City in an average week. Users have rated it 7.4/10 across 1,701 reviews.


Traveling to a place near Santiago?

Book flights to Santiago if you plan to visit one of these locations
Viña del Mar
Valparaíso
Santa Cruz
San Fernando
Valle Nevado
Pichilemu

Why use momondo?

Why should I use momondo to find a flight deal from Mexico City to Santiago?

Finding the right flight to Santiago from Mexico City is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Santiago quick and easy, saving you time and money.

Can I find flights from Mexico City to Santiago with flexible booking policies on momondo?

All flight searches from Mexico City to Santiago on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Mexico City to Santiago?

momondo provides multiple filters to help you find the best flight to Santiago from Mexico City. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Mexico City to Santiago right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Mexico City to Santiago flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.


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