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Cheap flights from Mexico City to Panama City from $164

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Mexico City to Panama City departing on 4/27. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Mexico City to Panama City

Cheap round-trip flights

KAYAK's recommended round-trip deals from the most popular airlines that fly from Mexico City to Panama City.
Avianca Logo
5:00 am - 2:40 pmMEX-PTY
8h 40m1 stop
Avianca Logo
3:20 am - 11:00 pmPTY-MEX
20h 40m1 stop
$343Avianca
Find Deal
Mon, May 19 - Wed, May 28
Avianca Logo
12:40 am - 10:10 amMEX-PTY
8h 30m1 stop
Avianca Logo
3:20 am - 6:05 pmPTY-MEX
15h 45m1 stop
$350Avianca
Find Deal
Sun, May 18 - Wed, May 28
Avianca Logo
12:40 am - 4:30 pmMEX-PTY
38h 50m1 stop
Avianca Logo
11:20 am - 1:55 amPTY-MEX
15h 35m1 stop
$351Avianca
Find Deal
Mon, May 26 - Tue, Jun 3
Avianca Logo
12:40 am - 10:10 amMEX-PTY
8h 30m1 stop
Avianca Logo
11:05 am - 11:00 pmPTY-MEX
12h 55m1 stop
$363Avianca
Find Deal
Sun, Aug 3 - Mon, Aug 11
Avianca Logo
5:00 am - 4:30 pmMEX-PTY
10h 30m2 stops
Avianca Logo
3:40 pm - 1:55 amPTY-MEX
11h 15m1 stop
$367Avianca
Find Deal
Wed, May 21 - Thu, May 22
Copa Airlines Logo
1:40 am - 6:21 amMEX-PTY
3h 41mnonstop
Copa Airlines Logo
9:30 pm - 12:15 amPTY-MEX
3h 45mnonstop
$373Copa Airlines
Find Deal
Sat, Aug 16 - Sun, Aug 24
Copa Airlines Logo
1:40 am - 6:24 amMEX-PTY
3h 44mnonstop
Copa Airlines Logo
9:30 pm - 12:15 amPTY-MEX
3h 45mnonstop
$374Copa Airlines
Find Deal
Mon, Jun 9 - Thu, Jul 31
 Logo
12:40 am - 8:55 amMEX-PTY
7h 15m1 stop
 Logo
8:10 pm - 9:55 amPTY-MEX
14h 45m3 stops
Wed, May 14 - Tue, May 20
 Logo
12:40 am - 10:10 amMEX-PTY
8h 30m1 stop
 Logo
8:10 pm - 9:55 amPTY-MEX
14h 45m3 stops
Tue, May 20 - Thu, May 22
United Airlines Logo
4:40 am - 6:37 pmMEX-PTY
12h 57m1 stop
United Airlines Logo
7:55 am - 11:10 pmPTY-MEX
16h 15m1 stop
$1,147United Airlines
Find Deal
Fri, Jun 6 - Fri, Jun 13

Avianca flights from Mexico City to Panama City

Our best Avianca deals on Mexico City to Panama City flight tickets
Avianca
May 19
MEX5:00 amMexico City Benito Juarez
8h 40m
1 stop
PTY2:40 pmPanama City Tocumen Intl
May 28
PTY3:20 amPanama City Tocumen Intl
20h 40m
1 stop
MEX11:00 pmMexico City Benito Juarez
Avianca
May 18
MEX12:40 amMexico City Benito Juarez
8h 30m
1 stop
PTY10:10 amPanama City Tocumen Intl
May 28
PTY3:20 amPanama City Tocumen Intl
15h 45m
1 stop
MEX6:05 pmMexico City Benito Juarez
Avianca
Apr 26
MEX12:40 amMexico City Benito Juarez
8h 30m
1 stop
PTY10:10 amPanama City Tocumen Intl
May 2
PTY3:40 pmPanama City Tocumen Intl
11h 15m
1 stop
MEX1:55 amMexico City Benito Juarez

Copa Airlines flights from Mexico City to Panama City

Our best Copa Airlines deals on Mexico City to Panama City flight tickets
Copa Airlines
Aug 16
MEX1:40 amMexico City Benito Juarez
3h 41m
PTY6:21 amPanama City Tocumen Intl
Aug 24
PTY9:30 pmPanama City Tocumen Intl
3h 45m
MEX12:15 amMexico City Benito Juarez
Copa Airlines
Jun 9
MEX1:40 amMexico City Benito Juarez
3h 44m
PTY6:24 amPanama City Tocumen Intl
Jul 31
PTY9:30 pmPanama City Tocumen Intl
3h 45m
MEX12:15 amMexico City Benito Juarez
Copa Airlines
Apr 25
MEX2:00 amMexico City Benito Juarez
3h 46m
PTY6:46 amPanama City Tocumen Intl
Apr 30
PTY7:08 pmPanama City Tocumen Intl
3h 52m
MEX10:00 pmMexico City Benito Juarez

See travel insights to Panama City from

How to get the cheapest flight ticket from Mexico City to Panama City

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Panama City?

In general, February is the cheapest month to fly from Mexico City to Panama City. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $429. If you’re not able to fly to Panama City in February, then March is your next best option. Flight prices from Mexico City to Panama City during March average around $431.

What is the cheapest day to depart on your flight to Panama City?

Our data shows that Thursday is the least expensive day to fly to Panama City. Tickets to fly out on this day can be as low as $542. If your travel schedule is flexible, try to avoid departing on a Saturday because tickets tend to average around $637. These prices are subject to change though, so be sure to set up a Price Alert for flights to Panama City.

What is the cheapest time of day to depart on your flight to Panama City?

Our most recent data shows that the best time of day to fly to Panama City is in the evening. Flights from Mexico City to Panama City during this time can be as low as $529. Try not to purchase tickets in the afternoon because they tend to be around $614. Of course, these prices can vary depending on the time of year and what airport you fly to.

What is the cheapest Mexico City Benito Juarez to Panama City Tocumen Intl flight route?

Fly from Mexico City Benito Juarez to Panama City Tocumen Intl for the best Mexico City Benito Juarez - Panama City Tocumen Intl flight prices

How far in advance should I book a flight to Panama City?

You are more likely to see cheaper flights to Panama City from Mexico City when booking 17 weeks ahead of your departure date. In general, you can expect to find flights to Panama City for around $473 when searching 17 weeks out.However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama City from Mexico City for as low as $430 on momondo.

What cabin class options are available on Mexico City Benito Juarez to Panama City Tocumen Intl flights?

There are 3 cabin classes available to choose from on Mexico City Benito Juarez to Panama City Tocumen Intl flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

How have Mexico City to Panama City flight prices changed over time?

As of April 2025, prices for Mexico City to Panama City flights are approximately 3% more expensive when compared to flights at the same time last year.

When to book flights from Mexico City to Panama City

Are you open to changing your travel dates? Check out the ideal times to fly from Mexico City to Panama City according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Mexico City to Panama City (MEX to PTY) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Mexico City to Panama City

Best Price Found

$164

Fastest flight time

3h 38m

Direct flights

Mon, Tue, Wed, Thu, Fri and Sun

Airports in Panama City

1 airport
The best one-way flight to Panama City from Mexico City in the past 72 hours is $164. The best round-trip flight deal from Mexico City to Panama City found on momondo in the last 72 hours is $343.
The fastest flight from Mexico City to Panama City takes 3h 38m
Direct flights go from Mexico City to Panama City on Monday, Tuesday, Wednesday, Thursday, Friday and Sunday. The only airline offering direct flights is Copa Airlines.
There is 1 airport near Panama City: Panama City Tocumen Intl (PTY)

  • How far is Mexico City Benito Juarez to Panama City Tocumen Intl by plane?

    There are 1496.2 mi between Mexico City Benito Juarez and Panama City Tocumen Intl. Typically, this will take 3h 38m by plane in normal conditions.

  • When did momondo last update prices for flights from Mexico City Benito Juarez Airport to Panama City Tocumen Intl Airport?

    Prices for flights from Mexico City Benito Juarez Airport to Panama City Tocumen Intl Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Mexico City Benito Juarez Airport to Panama City Tocumen Intl Airport?

  • How old do you have to be to fly from Mexico City Benito Juarez Airport to Panama City Tocumen Intl Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Mexico City Benito Juarez Airport to Panama City Tocumen Intl Airport.

  • What documentation or ID do you need to fly to Panama City Tocumen Intl Airport?

    The travel and health documents you'll need for your trip to Panama City Tocumen Intl Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Panama City Tocumen Intl Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Mexico City to Panama City?

  • What is the most popular airline from Mexico City to Panama City?


Best airlines flying from Mexico City to Panama City

Compare and see reviews for airlines that fly from Mexico City to Panama City with momondo
Airline
Rating
Free Cancellation
Price
AviancaPriceFrom $348Free CancellationRating
6.7
2,319 reviews
Search Avianca flights
Copa AirlinesPriceFrom $395Free CancellationRating
7.5
1,408 reviews
Search Copa Airlines flights
  • Copa Airlines Flights From Mexico City to Panama City

    Copa Airlines flight deals from Mexico City to Panama City start from $395 round-trip. Over the 43 Copa Airlines flights for this route in a normal week, average airfare is usually $530 round-trip - but some users have found much cheaper deals with momondo.


Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
San Blas

Why use momondo?

Why should I use momondo to find a flight deal from Mexico City to Panama City?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Mexico City to Panama City for you.

Can I find flights from Mexico City to Panama City with flexible booking policies on momondo?

momondo does allow users to show only those flights to Panama City from Mexico City which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Mexico City to Panama City?

momondo provides multiple filters to help you find the best flight to Panama City from Mexico City. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Mexico City to Panama City right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Mexico City to Panama City now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Panama City and let you know when they change.


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