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Cheap flights from Mexico City to Panama City from $173

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Mexico City to Panama City departing on 5/27. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Mexico City to Panama City

Cheap round-trip flights

KAYAK's recommended round-trip deals from the most popular airlines that fly from Mexico City to Panama City.
Avianca Logo
12:40 am - 4:30 pmMEX-PTY
14h 50m1 stop
Avianca Logo
9:50 am - 11:00 pmPTY-MEX
14h 10m1 stop
$350Avianca
Find Deal
Fri, May 16 - Sat, May 24
Copa Airlines Logo
1:40 am - 6:24 amMEX-PTY
3h 44mnonstop
Copa Airlines Logo
9:20 am - 12:10 pmPTY-MEX
3h 50mnonstop
$370Copa Airlines
Find Deal
Sun, Jun 15 - Mon, Jun 23
Copa Airlines Logo
1:40 am - 6:18 amMEX-PTY
3h 38mnonstop
Copa Airlines Logo
6:57 pm - 10:00 pmPTY-MEX
4h 03mnonstop
$371Copa Airlines
Find Deal
Sun, May 18 - Mon, Jun 2
Avianca Logo
12:40 am - 4:30 pmMEX-PTY
14h 50m1 stop
Avianca Logo
3:25 am - 12:05 pmPTY-MEX
9h 40m1 stop
$378Avianca
Find Deal
Fri, May 16 - Fri, May 23
Avianca Logo
12:40 am - 8:55 amMEX-PTY
7h 15m1 stop
Avianca Logo
5:25 pm - 3:05 amPTY-MEX
10h 40m1 stop
$393Avianca
Find Deal
Mon, Apr 28 - Tue, Apr 29
Avianca Logo
12:40 am - 4:30 pmMEX-PTY
14h 50m1 stop
Avianca Logo
10:05 pm - 12:05 pmPTY-MEX
15h 00m1 stop
$402Avianca
Find Deal
Fri, Jun 20 - Mon, Jun 30
Avianca Logo
12:40 am - 8:55 amMEX-PTY
7h 15m1 stop
Avianca Logo
5:25 pm - 3:05 amPTY-MEX
10h 40m1 stop
$404Avianca
Find Deal
Wed, May 21 - Wed, May 28
United Airlines Logo
6:30 am - 4:12 pmMEX-PTY
8h 42m1 stop
United Airlines Logo
3:20 pm - 11:10 pmPTY-MEX
8h 50m1 stop
$1,076United Airlines
Find Deal
Mon, Jun 9 - Mon, Jun 30
American Airlines Logo
1:10 pm - 12:54 pmMEX-PTY
22h 44m2 stops
American Airlines Logo
3:05 pm - 12:10 pmPTY-MEX
22h 05m2 stops
$1,412American Airlines
Find Deal
Wed, Jul 16 - Mon, Jul 21
United Airlines Logo
8:45 am - 2:14 pmMEX-PTY
28h 29m2 stops
United Airlines Logo
10:55 pm - 11:45 amPTY-MEX
13h 50m1 stop
$1,449United Airlines
Find Deal
Mon, May 5 - Thu, May 8

Copa Airlines flights from Mexico City to Panama City

Our best Copa Airlines deals on Mexico City to Panama City flight tickets
Copa Airlines
Jun 15
MEX1:40 amMexico City Benito Juarez
3h 44m
PTY6:24 amPanama City Tocumen Intl
Jun 23
PTY9:20 amPanama City Tocumen Intl
3h 50m
MEX12:10 pmMexico City Benito Juarez
Copa Airlines
May 18
MEX1:40 amMexico City Benito Juarez
3h 38m
PTY6:18 amPanama City Tocumen Intl
Jun 2
PTY6:57 pmPanama City Tocumen Intl
4h 03m
MEX10:00 pmMexico City Benito Juarez
Copa Airlines
Jul 19
MEX2:00 amMexico City Benito Juarez
3h 44m
PTY6:44 amPanama City Tocumen Intl
Oct 24
PTY9:21 pmPanama City Tocumen Intl
3h 54m
MEX12:15 amMexico City Benito Juarez

Avianca flights from Mexico City to Panama City

Our best Avianca deals on Mexico City to Panama City flight tickets
Avianca
May 16
MEX12:40 amMexico City Benito Juarez
14h 50m
1 stop
PTY4:30 pmPanama City Tocumen Intl
May 24
PTY9:50 amPanama City Tocumen Intl
14h 10m
1 stop
MEX11:00 pmMexico City Benito Juarez
Avianca
May 16
MEX12:40 amMexico City Benito Juarez
14h 50m
1 stop
PTY4:30 pmPanama City Tocumen Intl
May 23
PTY3:25 amPanama City Tocumen Intl
9h 40m
1 stop
MEX12:05 pmMexico City Benito Juarez
Avianca
Apr 28
MEX12:40 amMexico City Benito Juarez
7h 15m
1 stop
PTY8:55 amPanama City Tocumen Intl
Apr 29
PTY5:25 pmPanama City Tocumen Intl
10h 40m
1 stop
MEX3:05 amMexico City Benito Juarez

See travel insights to Panama City from

How to get the cheapest flight ticket from Mexico City to Panama City

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Mexico City and Panama City?

What is the cheapest month to fly to Panama City?

In general, February is the cheapest month to fly from Mexico City to Panama City. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $429. If you’re not able to fly to Panama City in February, then January is your next best option. Flight prices from Mexico City to Panama City during January average around $435.

What is the cheapest day to depart on your flight to Panama City?

Our data shows that Thursday is the least expensive day to fly to Panama City. Tickets to fly out on this day can be as low as $542. If your travel schedule is flexible, try to avoid departing on a Saturday because tickets tend to average around $637. These prices are subject to change though, so be sure to set up a Price Alert for flights to Panama City.

What is the cheapest time of day to depart on your flight to Panama City?

Our most recent data shows that the best time of day to fly to Panama City is in the evening. Flights from Mexico City to Panama City during this time can be as low as $530. Try not to purchase tickets in the afternoon because they tend to be around $622. Of course, these prices can vary depending on the time of year and what airport you fly to.

What is the cheapest Mexico City Benito Juarez to Panama City Tocumen Intl flight route?

Fly from Mexico City Benito Juarez to Panama City Tocumen Intl for the best Mexico City Benito Juarez - Panama City Tocumen Intl flight prices

How far in advance should I book a flight to Panama City?

You are more likely to see cheaper flights to Panama City from Mexico City when booking 25 weeks ahead of your departure date. In general, you can expect to find flights to Panama City for around $478 when searching 25 weeks out.However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama City from Mexico City for as low as $426 on momondo.

What cabin class options are available on Mexico City Benito Juarez to Panama City Tocumen Intl flights?

There are 3 cabin classes available to choose from on Mexico City Benito Juarez to Panama City Tocumen Intl flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

How have Mexico City to Panama City flight prices changed over time?

As of April 2025, prices for Mexico City to Panama City flights are approximately 9% more expensive when compared to flights at the same time last year.

When to book flights from Mexico City to Panama City

Are you open to changing your travel dates? Check out the ideal times to fly from Mexico City to Panama City according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Mexico City to Panama City (MEX to PTY) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Mexico City to Panama City

Best Price Found

$173

Fastest flight time

3h 38m

Direct flights

Every day

Airports in Panama City

1 airport
The best one-way flight to Panama City from Mexico City in the past 72 hours is $173. The best round-trip flight deal from Mexico City to Panama City found on momondo in the last 72 hours is $350.
The fastest flight from Mexico City to Panama City takes 3h 38m
Direct flights go from Mexico City to Panama City every day.
There is 1 airport near Panama City: Panama City Tocumen Intl (PTY)

  • How far is Mexico City Benito Juarez to Panama City Tocumen Intl by plane?

    There are 1496.2 mi between Mexico City Benito Juarez and Panama City Tocumen Intl. Typically, this will take 3h 38m by plane in normal conditions.

  • When did momondo last update prices for flights from Mexico City Benito Juarez Airport to Panama City Tocumen Intl Airport?

    Prices for flights from Mexico City Benito Juarez Airport to Panama City Tocumen Intl Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Mexico City Benito Juarez Airport to Panama City Tocumen Intl Airport?

  • How old do you have to be to fly from Mexico City Benito Juarez Airport to Panama City Tocumen Intl Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Mexico City Benito Juarez Airport to Panama City Tocumen Intl Airport.

  • What documentation or ID do you need to fly to Panama City Tocumen Intl Airport?

    The travel and health documents you'll need for your trip to Panama City Tocumen Intl Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Panama City Tocumen Intl Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Mexico City to Panama City?

  • What is the most popular airline from Mexico City to Panama City?


Best airlines flying from Mexico City to Panama City

Compare and see reviews for airlines that fly from Mexico City to Panama City with momondo
Airline
Rating
Free Cancellation
Price
AviancaPriceFrom $349Free CancellationRating
6.7
2,301 reviews
Search Avianca flights
Copa AirlinesPriceFrom $398Free CancellationRating
7.6
1,400 reviews
Search Copa Airlines flights
  • Copa Airlines Flights From Mexico City to Panama City

    Copa Airlines flight deals from Mexico City to Panama City start from $398 round-trip. Over the 14 Copa Airlines flights for this route in a normal week, average airfare is usually $537 round-trip - but some users have found much cheaper deals with momondo.


Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
San Blas

Why use momondo?

Why should I use momondo to find a flight deal from Mexico City to Panama City?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Mexico City to Panama City for you.

Can I find flights from Mexico City to Panama City with flexible booking policies on momondo?

momondo does allow users to show only those flights to Panama City from Mexico City which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Mexico City to Panama City?

momondo provides multiple filters to help you find the best flight to Panama City from Mexico City. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Mexico City to Panama City right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Mexico City to Panama City now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Panama City and let you know when they change.


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