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Cheap flights from Des Moines to Mexico City from $280

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Des Moines to Mexico City departing on 5/31. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Des Moines to Mexico City

Cheap round-trip flights

KAYAK's recommended round-trip deals from the most popular airlines that fly from Des Moines to Mexico City.
American Airlines Logo
5:00 am - 4:15 pmDSM-MEX
12h 15m1 stop
American Airlines Logo
5:00 am - 10:53 pmMEX-DSM
16h 53m1 stop
$474American Airlines
Find Deal
Thu, May 1 - Sun, May 4
Aeromexico Logo
5:35 am - 3:20 pmDSM-MEX
10h 45m2 stops
Aeromexico Logo
6:01 am - 5:50 pmMEX-DSM
10h 49m2 stops
$484Aeromexico
Find Deal
Sat, May 31 - Sat, Jun 7
 Logo
2:54 pm - 10:00 pmDSM-MEX
32h 06m2 stops
 Logo
6:20 am - 10:37 pmMEX-DSM
39h 17m2 stops
Sat, May 31 - Sat, Jun 7
Delta Logo
10:22 am - 9:05 pmDSM-MEX
11h 43m2 stops
Delta Logo
6:55 am - 10:30 pmMEX-DSM
14h 35m2 stops
$492Delta
Find Deal
Thu, May 1 - Wed, May 7
 Logo
2:54 pm - 10:00 pmDSM-MEX
32h 06m2 stops
 Logo
6:20 am - 10:37 pmMEX-DSM
39h 17m2 stops
Sat, May 31 - Sat, Jun 7
Delta Logo
11:30 am - 8:45 pmDSM-MEX
10h 15m1 stop
Delta Logo
7:05 am - 8:53 pmMEX-DSM
12h 48m2 stops
$505Delta
Find Deal
Thu, May 1 - Sun, May 4
United Airlines Logo
6:15 am - 3:40 pmDSM-MEX
10h 25m1 stop
United Airlines Logo
8:05 am - 9:45 pmMEX-DSM
12h 40m2 stops
$578United Airlines
Find Deal
Sun, Sep 14 - Sat, Sep 27
United Airlines Logo
6:00 am - 10:45 amDSM-MEX
5h 45m1 stop
United Airlines Logo
11:35 am - 10:22 pmMEX-DSM
9h 47m1 stop
$603United Airlines
Find Deal
Wed, May 28 - Tue, Jun 3
Air Canada Logo
3:15 pm - 11:15 pmDSM-MEX
33h 00m2 stops
Air Canada Logo
12:15 am - 5:14 pmMEX-DSM
15h 59m2 stops
$906Air Canada
Find Deal
Sun, Sep 14 - Fri, Sep 26
Air Canada Logo
6:00 am - 10:50 pmDSM-MEX
17h 50m2 stops
Air Canada Logo
12:15 am - 2:41 pmMEX-DSM
13h 26m2 stops
$1,009Air Canada
Find Deal
Mon, Jun 23 - Wed, Jun 25

American Airlines flights from Des Moines to Mexico City

Our best American Airlines deals on Des Moines to Mexico City flight tickets
American Airlines
May 1
DSM5:00 amDes Moines
12h 15m
1 stop
MEX4:15 pmMexico City Benito Juarez
May 4
MEX5:00 amMexico City Benito Juarez
16h 53m
1 stop
DSM10:53 pmDes Moines
American Airlines
May 1
DSM5:00 amDes Moines
12h 15m
1 stop
MEX4:15 pmMexico City Benito Juarez
May 4
MEX5:00 amMexico City Benito Juarez
16h 53m
1 stop
DSM10:53 pmDes Moines
American Airlines
May 1
DSM5:00 amDes Moines
12h 15m
1 stop
MEX4:15 pmMexico City Benito Juarez
May 4
MEX5:00 amMexico City Benito Juarez
16h 53m
1 stop
DSM10:53 pmDes Moines

Delta flights from Des Moines to Mexico City

Our best Delta deals on Des Moines to Mexico City flight tickets
Delta
May 1
DSM10:22 amDes Moines
11h 43m
2 stops
MEX9:05 pmMexico City Benito Juarez
May 7
MEX6:55 amMexico City Benito Juarez
14h 35m
2 stops
DSM10:30 pmDes Moines
Delta
May 1
DSM11:30 amDes Moines
10h 15m
1 stop
MEX8:45 pmMexico City Benito Juarez
May 4
MEX7:05 amMexico City Benito Juarez
12h 48m
2 stops
DSM8:53 pmDes Moines
Delta
May 1
DSM10:22 amDes Moines
11h 43m
2 stops
MEX9:05 pmMexico City Benito Juarez
May 4
MEX7:05 amMexico City Benito Juarez
12h 48m
2 stops
DSM8:53 pmDes Moines

See travel insights to Mexico City from

How to get the cheapest flight ticket from Des Moines to Mexico City

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Des Moines and Mexico City?

What is the cheapest month to fly to Mexico City?

The cheapest month to fly to Mexico City from Des Moines is in February. Flight prices, which tend to average around $557, are often lower during this time because this is during the off-season. If you aren’t able to travel during the month of February, then book flights to Mexico City from Des Moines during November instead. Flights to Mexico City in November, while not as cheap as those in February, still average around $563.

What is the cheapest day to depart on your flight to Mexico City?

Our data shows that Thursday is the least expensive day to fly to Mexico City. Tickets to fly out on this day can be as low as $610. On the other hand, Sunday is the most expensive day to depart from Des Moines because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $864.

What is the cheapest time of day to depart on your flight to Mexico City?

According to our data, the cheapest time of day to fly to Mexico City is in the morning. momondo users have found flights departing from Des Moines to Mexico City in the morning for as low as $692. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. At noon is when there is more demand to fly to Mexico City, so prices are often more expensive at around $822 per ticket.

How have Des Moines to Mexico City flight prices changed over time?

As of April 2025, prices for Des Moines to Mexico City flights are approximately 39% more expensive when compared to flights at the same time last year.

When to book flights from Des Moines to Mexico City

Are you open to changing your travel dates? Check out the ideal times to fly from Des Moines to Mexico City according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Des Moines to Mexico City (DSM to MEX) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Mexico City

Best Price Found

$280

Fastest flight time

5h 45m

Direct flights

None

Airports in Mexico City

1 airport
The best one-way flight to Mexico City from Des Moines in the past 72 hours is $280. The best round-trip flight deal from Des Moines to Mexico City found on momondo in the last 72 hours is $474.
The fastest flight from Des Moines to Mexico City takes 5h 45m
There are no direct flights from Des Moines to Mexico City. Popular non-direct route for this connection is Des Moines Airport - Mexico City Benito Juarez Airport.
There is 1 airport near Mexico City: Mexico City Benito Juarez (MEX)

  • How far is Des Moines to Mexico City Benito Juarez by plane?

    Mexico City Benito Juarez is 1564.5 mi away from Des Moines. By plane, this route typically takes 5h 45m.

  • When did momondo last update prices for flights from Des Moines Airport to Mexico City Benito Juarez Airport?

    Prices for flights from Des Moines Airport to Mexico City Benito Juarez Airport were last updated today.

  • How many operators does momondo search for flights from Des Moines Airport to Mexico City Benito Juarez Airport?

  • How old do you have to be to fly from Des Moines Airport to Mexico City Benito Juarez Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Des Moines Airport to Mexico City Benito Juarez Airport.

  • What documentation or ID do you need to fly to Mexico City Benito Juarez Airport?

    The travel and health documents you'll need for your trip to Mexico City Benito Juarez Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Mexico City Benito Juarez Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Des Moines to Mexico City?


Best airlines flying from Des Moines to Mexico City

Compare and see reviews for airlines that fly from Des Moines to Mexico City with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $509Free CancellationRating
8.0
7,916 reviews
Search Delta flights
American AirlinesPriceFrom $514Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights
United AirlinesPriceFrom $537Free CancellationRating
7.4
8,667 reviews
Search United Airlines flights

Traveling to a place near Mexico City?

Book flights to Mexico City if you plan to visit one of these locations
Cuernavaca
Tepoztlán
Taxco
Valle de Bravo

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Mexico City?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Mexico City from Des Moines.

Can I find flights from Des Moines to Mexico City with flexible booking policies on momondo?

Flights from Des Moines to Mexico City with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Des Moines to Mexico City?

momondo helps you find the best flight between Des Moines and Mexico City by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Des Moines to Mexico City right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Des Moines to Mexico City now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Mexico City and let you know when they change.


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