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Cheap flights from Des Moines to San Diego from $95

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Des Moines to San Diego departing on 5/4. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Des Moines to San Diego

Cheap round-trip flights

KAYAK's recommended round-trip deals from the most popular airlines that fly from Des Moines to San Diego.
2:43 pm - 4:19 pmDSM-SAN
3h 36mnonstop
5:12 pm - 10:34 pmSAN-DSM
3h 22mnonstop
$147Allegiant Air
Find Deal
Mon, Jun 2 - Fri, Jun 6
2:45 pm - 4:22 pmDSM-SAN
3h 37mnonstop
5:12 pm - 10:34 pmSAN-DSM
3h 22mnonstop
$170Allegiant Air
Find Deal
Fri, Jun 6 - Fri, Jun 13
7:27 pm - 12:14 amDSM-SAN
6h 47m1 stop
6:25 am - 6:37 pmSAN-DSM
10h 12m1 stop
$278Frontier
Find Deal
Fri, Apr 25 - Wed, Apr 30
7:20 pm - 12:13 amDSM-SAN
6h 53m1 stop
6:25 am - 6:30 pmSAN-DSM
10h 05m1 stop
$288Frontier
Find Deal
Mon, May 5 - Mon, May 12
12:50 pm - 6:09 pmDSM-SAN
7h 19m1 stop
2:49 pm - 11:39 pmSAN-DSM
6h 50m1 stop
$337American Airlines
Find Deal
Sat, May 10 - Sat, May 17
6:00 am - 12:28 pmDSM-SAN
8h 28m2 stops
1:58 pm - 10:45 pmSAN-DSM
6h 47m1 stop
$340United Airlines
Find Deal
Wed, Jun 4 - Mon, Jun 9
3:40 pm - 11:00 pmDSM-SAN
9h 20m1 stop
10:10 am - 7:55 pmSAN-DSM
7h 45m2 stops
$346Southwest
Find Deal
Thu, May 1 - Tue, May 6
5:56 pm - 11:22 pmDSM-SAN
7h 26m1 stop
2:54 pm - 11:52 pmSAN-DSM
6h 58m1 stop
$371American Airlines
Find Deal
Fri, Jun 6 - Tue, Jun 10
3:40 pm - 6:50 pmDSM-SAN
5h 10m1 stop
12:00 pm - 10:20 pmSAN-DSM
8h 20m2 stops
$376Southwest
Find Deal
Tue, Jun 3 - Tue, Jun 17
5:12 pm - 10:14 pmDSM-SAN
7h 02m1 stop
6:15 am - 4:15 pmSAN-DSM
8h 00m2 stops
$377United Airlines
Find Deal
Fri, Aug 1 - Wed, Aug 6

Allegiant Air flights from Des Moines to San Diego

Our best Allegiant Air deals on Des Moines to San Diego flight tickets
Allegiant Air
Jun 2
DSM2:43 pmDes Moines
3h 36m
SAN4:19 pmSan Diego
Jun 6
SAN5:12 pmSan Diego
3h 22m
DSM10:34 pmDes Moines
Allegiant Air
Jun 6
DSM2:45 pmDes Moines
3h 37m
SAN4:22 pmSan Diego
Jun 13
SAN5:12 pmSan Diego
3h 22m
DSM10:34 pmDes Moines
Allegiant Air
Aug 15
DSM2:54 pmDes Moines
3h 36m
SAN4:30 pmSan Diego
Aug 18
SAN5:20 pmSan Diego
3h 24m
DSM10:44 pmDes Moines

Frontier flights from Des Moines to San Diego

Our best Frontier deals on Des Moines to San Diego flight tickets
Frontier
Apr 25
DSM7:27 pmDes Moines
6h 47m
1 stop
SAN12:14 amSan Diego
Apr 30
SAN6:25 amSan Diego
10h 12m
1 stop
DSM6:37 pmDes Moines
Frontier
May 5
DSM7:20 pmDes Moines
6h 53m
1 stop
SAN12:13 amSan Diego
May 12
SAN6:25 amSan Diego
10h 05m
1 stop
DSM6:30 pmDes Moines
Frontier
Jun 2
DSM8:38 pmDes Moines
5h 17m
1 stop
SAN11:55 pmSan Diego
Jun 9
SAN6:25 amSan Diego
11h 28m
1 stop
DSM7:53 pmDes Moines

See travel insights to San Diego from

How to get the cheapest flight ticket from Des Moines to San Diego

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to San Diego?

If you are unable to visit San Diego during the month of June, then departing from Des Moines during the month July is also very affordable. Most momondo users find prices during this month for around $293.

What is the cheapest day to depart on your flight to San Diego?

The cheapest day to depart from Des Moines to San Diego is on a Monday. Travelers who choose to depart for San Diego on a Monday will often find tickets for as low as $201. If your travel schedule is flexible, try to avoid departing on a Sunday because tickets tend to average around $468. These prices are subject to change though, so be sure to set up a Price Alert for flights to San Diego.

What is the cheapest time of day to depart on your flight to San Diego?

The cheapest time of day to fly to San Diego is at noon when flights can be purchased for as low as $212. Flights in the morning are often more expensive with an average ticket price of $433.

What is the cheapest Des Moines to San Diego flight route?

Fly from Des Moines to San Diego for the best Des Moines - San Diego flight prices

How far in advance should I book a flight to San Diego?

You are more likely to see cheaper flights to San Diego from Des Moines when booking 15 weeks ahead of your departure date. In general, you can expect to find flights to San Diego for around $388 when searching 15 weeks out.However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Diego from Des Moines for as low as $313 on momondo.

What cabin class options are available on Des Moines to San Diego flights?

There are 1 cabin classes available to choose from on Des Moines to San Diego flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

How have Des Moines to San Diego flight prices changed over time?

As of March 2025, prices for Des Moines to San Diego flights are approximately 318% more expensive when compared to flights at the same time last year.

When to book flights from Des Moines to San Diego

Are you open to changing your travel dates? Check out the ideal times to fly from Des Moines to San Diego according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Des Moines to San Diego (DSM to SAN) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to San Diego

Best Price Found

$95

Fastest flight time

3h 31m

Direct flights

Tue and Sat

Airports in San Diego

1 airport
The best one-way flight to San Diego from Des Moines in the past 72 hours is $95. The best round-trip flight deal from Des Moines to San Diego found on momondo in the last 72 hours is $147.
The fastest flight from Des Moines to San Diego takes 3h 31m
Direct flights go from Des Moines to San Diego on Tuesday and Saturday. The only airline offering direct flights is Allegiant Air.
There is 1 airport near San Diego: San Diego (SAN)

  • How far is Des Moines to San Diego by plane?

    Des Moines and San Diego are 1426.2 mi apart from one another. In terms of flight time, this usually takes a little over 3h 31m.

  • When did momondo last update prices for flights from Des Moines Airport to San Diego Airport?

    Prices for flights from Des Moines Airport to San Diego Airport were last updated today.

  • How many operators does momondo search for flights from Des Moines Airport to San Diego Airport?

  • How old do you have to be to fly from Des Moines Airport to San Diego Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Des Moines Airport to San Diego Airport.

  • What documentation or ID do you need to fly to San Diego Airport?

    The necessary travel and health documents for your San Diego Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Des Moines to San Diego?

  • What is the most popular airline from Des Moines to San Diego?


Best airlines flying from Des Moines to San Diego

Compare and see reviews for airlines that fly from Des Moines to San Diego with momondo
Airline
Rating
Free Cancellation
Price
FrontierPriceFrom $118Free CancellationRating
6.0
3,271 reviews
Search Frontier flights
Allegiant AirPriceFrom $140Free CancellationRating
7.3
731 reviews
Search Allegiant Air flights
DeltaPriceFrom $296Free CancellationRating
8.0
7,895 reviews
Search Delta flights
American AirlinesPriceFrom $306Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights
United AirlinesPriceFrom $326Free CancellationRating
7.4
8,603 reviews
Search United Airlines flights
SouthwestPriceFrom $359Free CancellationRating
8.0
4,273 reviews
Search Southwest flights

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
Chula Vista
Coronado
El Cajon
Julian
La Mesa
National City
Imperial Beach
Lemon Grove
San Ysidro
Borrego Springs
Poway
Alpine
Santee

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to San Diego?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to San Diego from Des Moines.

Can I find flights from Des Moines to San Diego with flexible booking policies on momondo?

Flights from Des Moines to San Diego with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Des Moines to San Diego?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to San Diego from Des Moines.

I’m not ready to book a flight from Des Moines to San Diego right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Des Moines to San Diego flights. All you need is a valid email address and we will do the rest; it is that quick and easy.


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