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Cheap flights from Des Moines to San Diego from $69

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Des Moines to San Diego departing on 5/26. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Des Moines to San Diego

Cheap round-trip flights

KAYAK's recommended round-trip deals from the most popular airlines that fly from Des Moines to San Diego.
Allegiant Air Logo
2:43 pm - 4:19 pmDSM-SAN
3h 36mnonstop
Allegiant Air Logo
5:09 pm - 10:33 pmSAN-DSM
3h 24mnonstop
$147Allegiant Air
Find Deal
vie., may. 30 - lun., jun. 2
Allegiant Air Logo
2:43 pm - 4:19 pmDSM-SAN
3h 36mnonstop
Allegiant Air Logo
5:09 pm - 10:33 pmSAN-DSM
3h 24mnonstop
$152Allegiant Air
Find Deal
lun., may. 26 - vie., may. 30
Frontier Logo
7:20 pm - 12:13 amDSM-SAN
6h 53m1 stop
Frontier Logo
10:38 am - 6:30 pmSAN-DSM
5h 52m1 stop
$238Frontier
Find Deal
vie., may. 16 - lun., may. 19
Frontier Logo
7:20 pm - 12:13 amDSM-SAN
6h 53m1 stop
Frontier Logo
8:54 pm - 6:20 pmSAN-DSM
19h 26m1 stop
$248Frontier
Find Deal
lun., may. 12 - jue., may. 15
American Airlines Logo
2:44 pm - 6:26 pmDSM-SAN
5h 42m1 stop
American Airlines Logo
9:55 am - 7:04 pmSAN-DSM
7h 09m1 stop
$288American Airlines
Find Deal
sáb., may. 31 - sáb., jun. 7
United Airlines Logo
5:45 am - 9:24 amDSM-SAN
5h 39m1 stop
United Airlines Logo
2:30 pm - 11:39 pmSAN-DSM
7h 09m2 stops
$292United Airlines
Find Deal
mié., may. 14 - lun., may. 19
American Airlines Logo
5:27 pm - 9:53 pmDSM-SAN
6h 26m1 stop
American Airlines Logo
6:15 am - 4:37 pmSAN-DSM
8h 22m1 stop
$311American Airlines
Find Deal
jue., may. 15 - jue., may. 22
United Airlines Logo
5:03 pm - 10:28 pmDSM-SAN
7h 25m1 stop
United Airlines Logo
10:50 am - 8:51 pmSAN-DSM
8h 01m2 stops
$324United Airlines
Find Deal
jue., sep. 4 - dom., sep. 7
Southwest Logo
6:10 am - 3:25 pmDSM-SAN
11h 15m2 stops
Southwest Logo
2:35 pm - 10:55 pmSAN-DSM
6h 20m2 stops
$393Southwest
Find Deal
vie., jul. 4 - jue., jul. 10
Southwest Logo
1:45 pm - 7:40 pmDSM-SAN
7h 55m2 stops
Southwest Logo
2:00 pm - 12:05 amSAN-DSM
8h 05m1 stop
$472Southwest
Find Deal
mar., jul. 15 - dom., jul. 20

Allegiant Air flights from Des Moines to San Diego

Our best Allegiant Air deals on Des Moines to San Diego flight tickets
Allegiant Air
May 30
DSM2:43 pmDes Moines
3h 36m
SAN4:19 pmSan Diego
Jun 2
SAN5:09 pmSan Diego
3h 24m
DSM10:33 pmDes Moines
Allegiant Air
May 26
DSM2:43 pmDes Moines
3h 36m
SAN4:19 pmSan Diego
May 30
SAN5:09 pmSan Diego
3h 24m
DSM10:33 pmDes Moines
Allegiant Air
May 26
DSM2:43 pmDes Moines
3h 36m
SAN4:19 pmSan Diego
May 30
SAN5:09 pmSan Diego
3h 24m
DSM10:33 pmDes Moines

Frontier flights from Des Moines to San Diego

Our best Frontier deals on Des Moines to San Diego flight tickets
Frontier
Apr 21
DSM8:17 pmDes Moines
5h 57m
1 stop
SAN12:14 amSan Diego
Apr 25
SAN6:25 amSan Diego
10h 12m
1 stop
DSM6:37 pmDes Moines
Frontier
May 16
DSM7:20 pmDes Moines
6h 53m
1 stop
SAN12:13 amSan Diego
May 19
SAN10:38 amSan Diego
5h 52m
1 stop
DSM6:30 pmDes Moines
Frontier
May 12
DSM7:20 pmDes Moines
6h 53m
1 stop
SAN12:13 amSan Diego
May 15
SAN8:54 pmSan Diego
19h 26m
1 stop
DSM6:20 pmDes Moines

See travel insights to San Diego from

How to get the cheapest flight ticket from Des Moines to San Diego

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to San Diego?

If you are unable to visit San Diego during the month of June, then departing from Des Moines during the month July is also very affordable. Most momondo users find prices during this month for around $251.

What is the cheapest day to depart on your flight to San Diego?

The cheapest day to depart from Des Moines to San Diego is on a Monday. Travelers who choose to depart for San Diego on a Monday will often find tickets for as low as $201. If your travel schedule is flexible, try to avoid departing on a Sunday because tickets tend to average around $468. These prices are subject to change though, so be sure to set up a Price Alert for flights to San Diego.

What is the cheapest time of day to depart on your flight to San Diego?

The cheapest time of day to fly to San Diego is at noon when flights can be purchased for as low as $210. Flights in the morning are often more expensive with an average ticket price of $433.

What is the cheapest Des Moines to San Diego flight route?

Fly from Des Moines to San Diego for the best Des Moines - San Diego flight prices

How far in advance should I book a flight to San Diego?

You are more likely to see cheaper flights to San Diego from Des Moines when booking 15 weeks ahead of your departure date. In general, you can expect to find flights to San Diego for around $383 when searching 15 weeks out.However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Diego from Des Moines for as low as $323 on momondo.

What cabin class options are available on Des Moines to San Diego flights?

There are 1 cabin classes available to choose from on Des Moines to San Diego flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

How have Des Moines to San Diego flight prices changed over time?

As of April 2025, prices for Des Moines to San Diego flights are approximately 181% more expensive when compared to flights at the same time last year.

When to book flights from Des Moines to San Diego

Are you open to changing your travel dates? Check out the ideal times to fly from Des Moines to San Diego according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Des Moines to San Diego (DSM to SAN) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to San Diego

Best Price Found

$69

Fastest flight time

3h 31m

Direct flights

Tue and Sat

Airports in San Diego

1 airport
The best one-way flight to San Diego from Des Moines in the past 72 hours is $69. The best round-trip flight deal from Des Moines to San Diego found on momondo in the last 72 hours is $147.
The fastest flight from Des Moines to San Diego takes 3h 31m
Direct flights go from Des Moines to San Diego on Tuesday and Saturday. The only airline offering direct flights is Allegiant Air.
There is 1 airport near San Diego: San Diego (SAN)

  • How far is Des Moines to San Diego by plane?

    Des Moines and San Diego are 1426.2 mi apart from one another. In terms of flight time, this usually takes a little over 3h 36m.

  • When did momondo last update prices for flights from Des Moines Airport to San Diego Airport?

    Prices for flights from Des Moines Airport to San Diego Airport were last updated today.

  • How many operators does momondo search for flights from Des Moines Airport to San Diego Airport?

  • How old do you have to be to fly from Des Moines Airport to San Diego Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Des Moines Airport to San Diego Airport.

  • What documentation or ID do you need to fly to San Diego Airport?

    The necessary travel and health documents for your San Diego Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Des Moines to San Diego?

  • What is the most popular airline from Des Moines to San Diego?


Best airlines flying from Des Moines to San Diego

Compare and see reviews for airlines that fly from Des Moines to San Diego with momondo
Airline
Rating
Free Cancellation
Price
FrontierPriceFrom $125Free CancellationRating
6.0
3,281 reviews
Search Frontier flights
Allegiant AirPriceFrom $140Free CancellationRating
7.3
734 reviews
Search Allegiant Air flights
DeltaPriceFrom $296Free CancellationRating
8.0
7,916 reviews
Search Delta flights
American AirlinesPriceFrom $306Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights
United AirlinesPriceFrom $330Free CancellationRating
7.4
8,665 reviews
Search United Airlines flights
SouthwestPriceFrom $359Free CancellationRating
8.0
4,282 reviews
Search Southwest flights

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
Chula Vista
Coronado
El Cajon
Julian
La Mesa
National City
Imperial Beach
Lemon Grove
San Ysidro
Borrego Springs
Poway
Alpine
Santee

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to San Diego?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to San Diego from Des Moines.

Can I find flights from Des Moines to San Diego with flexible booking policies on momondo?

Flights from Des Moines to San Diego with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Des Moines to San Diego?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to San Diego from Des Moines.

I’m not ready to book a flight from Des Moines to San Diego right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Des Moines to San Diego flights. All you need is a valid email address and we will do the rest; it is that quick and easy.


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