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Cheap flights from Des Moines to Knoxville from $248

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Des Moines to Knoxville departing on 12/18. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Des Moines to Knoxville

Cheap round-trip flights

These are some of the best round-trip flight deals from Des Moines to Knoxville that have been recently found on momondo from popular airlines, departing in the coming months.

Cheap one-way flights

Flying one-way? These are some of the best deals recently discovered on momondo for flights from Des Moines to Knoxville.

Cheap last minute flights

Planning a quick getaway from Des Moines to Knoxville? These are the last-minute flight deals available now.

Cheap direct flights

If you prefer a non-stop journey, check out our latest direct flight deals to Knoxville, so you can enjoy a seamless trip without layovers.

Cheap bus & train deals from Des Moines to Knoxville

Find recent round-trip train or bus tickets from Des Moines to Knoxville.

All round-trip flight deals to Knoxville

The cheapest plane tickets to Knoxville found on KAYAK recently.
6:35 am - 11:43 amDSM-TYS
4h 08m1 stop
6:36 am - 11:30 amTYS-DSM
5h 54m1 stop
$248Delta
Find Deal
Wed, Dec 18 - Wed, Jan 8
4:00 pm - 12:05 amDSM-TYS
7h 05m2 stops
6:45 pm - 10:08 pmTYS-DSM
4h 23m1 stop
$253American Airlines
Find Deal
Wed, Dec 18 - Wed, Jan 8
5:03 am - 11:14 amDSM-TYS
5h 11m1 stop
6:11 pm - 11:05 pmTYS-DSM
5h 54m1 stop
$258American Airlines
Find Deal
Thu, Dec 5 - Mon, Dec 9
5:51 am - 2:21 pmDSM-TYS
7h 30m2 stops
2:48 pm - 10:08 pmTYS-DSM
8h 20m2 stops
$288American Airlines
Find Deal
Wed, Dec 18 - Wed, Jan 8
5:40 am - 2:21 pmDSM-TYS
7h 41m2 stops
2:48 pm - 10:08 pmTYS-DSM
8h 20m2 stops
$333American Airlines
Find Deal
Wed, Dec 18 - Wed, Jan 8
5:03 am - 11:14 amDSM-TYS
5h 11m1 stop
4:10 pm - 11:52 pmTYS-DSM
8h 42m2 stops
$339American Airlines
Find Deal
Thu, Dec 5 - Mon, Dec 9
5:29 pm - 11:42 pmDSM-TYS
5h 13m1 stop
6:47 pm - 9:40 pmTYS-DSM
3h 53m1 stop
$400American Airlines
Find Deal
Sun, Mar 2 - Fri, Mar 7
2:08 pm - 11:34 pmDSM-TYS
8h 26m1 stop
6:00 am - 12:43 pmTYS-DSM
7h 43m1 stop
$486Allegiant Air
Find Deal
Sat, Dec 21 - Mon, Dec 30
7:00 am - 2:17 pmDSM-TYS
30h 17m3 stops
6:30 am - 3:43 pmTYS-DSM
10h 13m1 stop
Thu, Dec 5 - Mon, Dec 9
9:55 am - 11:34 pmDSM-TYS
12h 39m2 stops
6:00 am - 12:43 pmTYS-DSM
7h 43m1 stop
$552Allegiant Air
Find Deal
Sat, Dec 21 - Mon, Dec 30
DSM-TYS
654 mimulti-stop
Multiple Airlines
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2:24 pm - 8:24 pmDSM-TYS
5h 00m1 stop
12:01 pm - 5:35 pmTYS-DSM
6h 34m1 stop
$338Delta
Find Deal
Fri, Nov 22 - Mon, Nov 25
3:30 pm - 12:19 amDSM-TYS
7h 49m1 stop
5:00 am - 11:07 amTYS-DSM
7h 07m2 stops
$343American Airlines
Find Deal
Fri, Nov 22 - Mon, Nov 25
3:20 pm - 10:24 pmDSM-TYS
6h 04m1 stop
7:05 am - 2:17 pmTYS-DSM
8h 12m1 stop
$363United Airlines
Find Deal
Fri, Nov 22 - Mon, Nov 25
3:20 pm - 10:24 pmDSM-TYS
6h 04m1 stop
5:45 am - 2:23 pmTYS-DSM
9h 38m2 stops
$368United Airlines
Find Deal
Fri, Nov 22 - Mon, Nov 25
3:20 pm - 11:59 pmDSM-TYS
7h 39m2 stops
5:45 am - 2:23 pmTYS-DSM
9h 38m2 stops
$384United Airlines
Find Deal
Fri, Nov 22 - Mon, Nov 25
3:20 pm - 10:24 pmDSM-TYS
6h 04m1 stop
7:00 am - 10:29 amTYS-DSM
4h 29m1 stop
$444United Airlines
Find Deal
Fri, Nov 22 - Tue, Nov 26
3:20 pm - 10:24 pmDSM-TYS
6h 04m1 stop
5:45 am - 2:23 pmTYS-DSM
9h 38m2 stops
$449United Airlines
Find Deal
Fri, Nov 22 - Tue, Nov 26
3:20 pm - 11:59 pmDSM-TYS
7h 39m2 stops
5:45 am - 2:23 pmTYS-DSM
9h 38m2 stops
$489United Airlines
Find Deal
Fri, Nov 22 - Tue, Nov 26
3:20 pm - 11:59 pmDSM-TYS
7h 39m2 stops
5:45 am - 2:23 pmTYS-DSM
9h 38m3 stops
$817United Airlines
Find Deal
Fri, Nov 22 - Mon, Nov 25

American Airlines flights from Des Moines to Knoxville

Our best American Airlines deals on Des Moines to Knoxville flight tickets
American Airlines
Dec 18
DSM4:00 pmDes Moines
7h 05m
2 stops
TYS12:05 amKnoxville McGhee Tyson
Jan 8
TYS6:45 pmKnoxville McGhee Tyson
4h 23m
1 stop
DSM10:08 pmDes Moines
American Airlines
Dec 5
DSM5:03 amDes Moines
5h 11m
1 stop
TYS11:14 amKnoxville McGhee Tyson
Dec 9
TYS6:11 pmKnoxville McGhee Tyson
5h 54m
1 stop
DSM11:05 pmDes Moines
American Airlines
Dec 5
DSM12:23 pmDes Moines
8h 25m
1 stop
TYS9:48 pmKnoxville McGhee Tyson
Dec 12
TYS5:16 amKnoxville McGhee Tyson
8h 32m
1 stop
DSM12:48 pmDes Moines

Allegiant Air flights from Des Moines to Knoxville

Our best Allegiant Air deals on Des Moines to Knoxville flight tickets
Allegiant Air
Dec 21
DSM2:08 pmDes Moines
8h 26m
1 stop
TYS11:34 pmKnoxville McGhee Tyson
Dec 30
TYS6:00 amKnoxville McGhee Tyson
7h 43m
1 stop
DSM12:43 pmDes Moines
Allegiant Air
Dec 21
DSM9:55 amDes Moines
12h 39m
2 stops
TYS11:34 pmKnoxville McGhee Tyson
Dec 30
TYS6:00 amKnoxville McGhee Tyson
7h 43m
1 stop
DSM12:43 pmDes Moines

See travel insights to Knoxville from

How to get the cheapest flight ticket from Des Moines to Knoxville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Knoxville?

The month of February is, on average, the cheapest month to fly to Knoxville from Des Moines, with most prices found around $303. If you aren’t able to travel during the month of February, then book flights to Knoxville from Des Moines during January instead. Flights to Knoxville in January, while not as cheap as those in February, still average around $321.

What is the cheapest day to depart on your flight to Knoxville?

The cheapest day to depart from Des Moines to Knoxville is on a Saturday. Travelers who choose to depart for Knoxville on a Saturday will often find tickets for as low as $292. When flying out on a Monday, the most expensive travel day of the week, you can expect to see flight prices from Des Moines to Knoxville for around $423.

What is the cheapest time of day to depart on your flight to Knoxville?

In the evening is the cheapest time of day to fly from Des Moines to Knoxville when you can find flight prices for as low as $0. Flying to Knoxville in the evening is an ideal time because this is during off-peak travel hours. In contrast, the most expensive time of day to depart to Knoxville is in the morning when prices are around $363.

How far in advance should I book a flight to Knoxville?

We recommend purchasing flights from Des Moines to Knoxville 21 days ahead of your departure date because this is when momondo users tend to see the best flight rates. On average, our users have found flights to Knoxville for $360. Keep in mind that you might also find cheap flights to Knoxville outside of this time window. In fact, momondo users recently found flights from Des Moines to Knoxville for $208.

Can stopping save me money on Des Moines to Knoxville flights?

You could potentially save up to 16% on your flight if you consider stops on a Des Moines to Knoxville flight.

When to book flights from Des Moines to Knoxville

Are you open to changing your travel dates? Check out the ideal times to fly from Des Moines to Knoxville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Des Moines to Knoxville (DSM to TYS) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Knoxville

Best Price Found

$248

Fastest flight time

4h 08m

Direct flights

None

Airports in Knoxville

1 airport
The best flight deal from Des Moines to Knoxville found on momondo in the last 72 hours is $248
The fastest flight from Des Moines to Knoxville takes 4h 08m
There are no direct flights from Des Moines to Knoxville. Popular non-direct route for this connection is Des Moines Airport - Knoxville McGhee Tyson Airport.
There is 1 airport near Knoxville: Knoxville McGhee Tyson (TYS)

  • How far is Des Moines to Knoxville McGhee Tyson by plane?

    Des Moines and Knoxville McGhee Tyson are 650.4 mi apart from one another. Flights usually cover this in 4h 08m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Des Moines Airport to Knoxville McGhee Tyson Airport?

    Prices for flights from Des Moines Airport to Knoxville McGhee Tyson Airport are updated daily.

  • How many operators does momondo search for flights from Des Moines Airport to Knoxville McGhee Tyson Airport?

  • How old do you have to be to fly from Des Moines Airport to Knoxville McGhee Tyson Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Des Moines Airport to Knoxville McGhee Tyson Airport.

  • What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?

    The travel and health documents you'll need for your trip to Knoxville McGhee Tyson Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Knoxville McGhee Tyson Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Des Moines to Knoxville?


Best airlines flying from Des Moines to Knoxville

Compare and see reviews for airlines that fly from Des Moines to Knoxville with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $219Free CancellationRating
8.0
8,755 reviews
Search Delta flights
American AirlinesPriceFrom $232Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights
United AirlinesPriceFrom $248Free CancellationRating
7.4
9,172 reviews
Search United Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Knoxville?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Knoxville from Des Moines.

Can I find flights from Des Moines to Knoxville with flexible booking policies on momondo?

Yes. All flights to Knoxville from Des Moines on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Des Moines to Knoxville?

Once you have performed a search for Des Moines to Knoxville flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Des Moines to Knoxville right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Knoxville, momondo offers a useful price alert feature which will track prices for flights to Knoxville from Des Moines and alert you when they change.


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