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Cheap flights from Des Moines to Charleston from $278

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Des Moines to Charleston departing on 1/9. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Des Moines to Charleston

Cheap round-trip flights

These are some of the best round-trip flight deals from Des Moines to Charleston that have been recently found on momondo from popular airlines, departing in the coming months.

Cheap one-way flights

Flying one-way? These are some of the best deals recently discovered on momondo for flights from Des Moines to Charleston.

Cheap last minute flights

Planning a quick getaway from Des Moines to Charleston? These are the last-minute flight deals available now.

Cheap direct flights

If you prefer a non-stop journey, check out our latest direct flight deals to Charleston, so you can enjoy a seamless trip without layovers.

Cheap bus & train deals from Des Moines to Charleston

Find recent round-trip train or bus tickets from Des Moines to Charleston.

All round-trip flight deals to Charleston

The cheapest plane tickets to Charleston found on KAYAK recently.
8:00 am - 10:58 pmDSM-CHS
13h 58m1 stop
7:15 am - 3:50 pmCHS-DSM
9h 35m1 stop
Thu, Jan 9 - Thu, Jan 16
4:15 pm - 11:54 pmDSM-CHS
6h 39m1 stop
1:42 pm - 9:13 pmCHS-DSM
8h 31m1 stop
$306Delta
Find Deal
Sat, Jan 18 - Sat, Jan 25
4:15 pm - 11:54 pmDSM-CHS
6h 39m1 stop
6:00 am - 2:07 pmCHS-DSM
9h 07m2 stops
$311Delta
Find Deal
Sat, Jan 18 - Sat, Jan 25
7:00 am - 9:39 pmDSM-CHS
13h 39m1 stop
3:10 pm - 11:25 pmCHS-DSM
9h 15m2 stops
Fri, Feb 28 - Mon, Mar 3
5:30 am - 5:18 pmDSM-CHS
10h 48m2 stops
5:10 am - 11:35 amCHS-DSM
7h 25m2 stops
$316American Airlines
Find Deal
Sat, Jan 18 - Sat, Jan 25
7:30 am - 5:18 pmDSM-CHS
8h 48m2 stops
5:10 am - 12:11 pmCHS-DSM
8h 01m2 stops
$326American Airlines
Find Deal
Tue, Jan 28 - Sat, Feb 1
5:30 am - 7:20 pmDSM-CHS
12h 50m2 stops
12:00 pm - 11:00 pmCHS-DSM
12h 00m2 stops
$361Southwest
Find Deal
Fri, Feb 28 - Mon, Mar 3
11:29 am - 11:04 pmDSM-CHS
10h 35m2 stops
4:45 pm - 9:23 pmCHS-DSM
5h 38m1 stop
$391United Airlines
Find Deal
Sat, Mar 1 - Tue, Mar 4
8:00 am - 11:46 pmDSM-CHS
14h 46m2 stops
6:15 am - 10:35 amCHS-DSM
5h 20m1 stop
$411United Airlines
Find Deal
Thu, Jan 9 - Thu, Jan 16
5:25 am - 3:30 pmDSM-CHS
9h 05m2 stops
6:10 am - 11:00 amCHS-DSM
5h 50m2 stops
$436Southwest
Find Deal
Fri, Jun 13 - Wed, Jun 18
6:26 am - 2:26 pmDSM-CHS
7h 00m1 stop
$318American Airlines
Find Deal
Sun, Jan 5
11:58 am - 10:06 pmDSM-CHS
9h 08m2 stops
$323American Airlines
Find Deal
Sun, Jan 5
3:46 pm - 7:51 pmDSM-CHS
27h 05m3 stops
Sun, Jan 5
6:00 am - 12:06 pmDSM-CHS
29h 06m2 stops
7:00 am - 9:02 amCHS-DSM
27h 02m2 stops
Tue, Dec 31 - Sat, Jan 4
2:53 pm - 8:11 pmDSM-CHS
28h 18m2 stops
7:00 am - 10:33 pmCHS-DSM
16h 33m2 stops
Mon, Dec 30 - Wed, Jan 1
2:02 pm - 11:46 pmDSM-CHS
8h 44m2 stops
8:23 pm - 11:59 pmCHS-DSM
4h 36m1 stop
$755American Airlines
Find Deal
Tue, Dec 31 - Sat, Jan 4
1:15 pm - 7:04 pmDSM-CHS
4h 49m1 stop
5:27 pm - 10:25 pmCHS-DSM
5h 58m1 stop
$756Delta
Find Deal
Tue, Dec 31 - Sat, Jan 4
2:02 pm - 11:46 pmDSM-CHS
8h 44m2 stops
6:58 am - 2:59 pmCHS-DSM
9h 01m2 stops
$760American Airlines
Find Deal
Wed, Jan 1 - Sun, Jan 5
5:39 pm - 12:24 amDSM-CHS
5h 45m1 stop
6:58 am - 1:39 pmCHS-DSM
7h 41m1 stop
$876American Airlines
Find Deal
Sun, Dec 29 - Wed, Jan 1
6:55 am - 4:15 pmDSM-CHS
8h 20m2 stops
5:27 pm - 8:46 pmCHS-DSM
4h 19m1 stop
$881Delta
Find Deal
Sun, Dec 29 - Wed, Jan 1
5:30 am - 8:55 pmDSM-CHS
14h 25m2 stops
7:45 am - 7:10 pmCHS-DSM
12h 25m2 stops
$886Southwest
Find Deal
Sun, Dec 29 - Wed, Jan 1
2:53 pm - 8:11 pmDSM-CHS
28h 18m2 stops
1:16 pm - 9:58 pmCHS-DSM
33h 42m3 stops
Mon, Dec 30 - Wed, Jan 1
2:20 pm - 8:26 amDSM-CHS
17h 06m2 stops
1:16 pm - 9:58 pmCHS-DSM
33h 42m3 stops
$1,116
Find Deal
Sun, Dec 29 - Wed, Jan 1

Southwest flights from Des Moines to Charleston

Our best Southwest deals on Des Moines to Charleston flight tickets
Southwest
Feb 28
DSM5:30 amDes Moines
12h 50m
2 stops
CHS7:20 pmCharleston
Mar 3
CHS12:00 pmCharleston
12h 00m
2 stops
DSM11:00 pmDes Moines
Southwest
Jun 13
DSM5:25 amDes Moines
9h 05m
2 stops
CHS3:30 pmCharleston
Jun 18
CHS6:10 amCharleston
5h 50m
2 stops
DSM11:00 amDes Moines
Southwest
Jun 13
DSM5:25 amDes Moines
7h 35m
1 stop
CHS2:00 pmCharleston
Jun 18
CHS6:10 amCharleston
5h 50m
2 stops
DSM11:00 amDes Moines

United Airlines flights from Des Moines to Charleston

Our best United Airlines deals on Des Moines to Charleston flight tickets
United Airlines
Mar 1
DSM11:29 amDes Moines
10h 35m
2 stops
CHS11:04 pmCharleston
Mar 4
CHS4:45 pmCharleston
5h 38m
1 stop
DSM9:23 pmDes Moines
United Airlines
Jan 9
DSM8:00 amDes Moines
14h 46m
2 stops
CHS11:46 pmCharleston
Jan 16
CHS6:15 amCharleston
5h 20m
1 stop
DSM10:35 amDes Moines
United Airlines
Mar 1
DSM11:29 amDes Moines
10h 35m
2 stops
CHS11:04 pmCharleston
Mar 2
CHS6:15 amCharleston
5h 22m
1 stop
DSM10:37 amDes Moines

See travel insights to Charleston from

How to get the cheapest flight ticket from Des Moines to Charleston

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Charleston?

The cheapest month to fly to Charleston from Des Moines is in January. Flight prices, which tend to average around $336, are often lower during this time because this is during the off-season. The month of September is another great option to travel to Charleston, with average flight prices from Des Moines averaging around $341.

What is the cheapest day to depart on your flight to Charleston?

The cheapest day to depart from Des Moines to Charleston is on a Monday. Travelers who choose to depart for Charleston on a Monday will often find tickets for as low as $379. The most expensive day to fly to Charleston is Thursday, with ticket prices averaging around $508.

What is the cheapest time of day to depart on your flight to Charleston?

The cheapest time of day to fly to Charleston is in the afternoon when flights can be purchased for as low as $386. In the morning is when there is more demand to fly to Charleston, so prices are often more expensive at around $405 per ticket.

How far in advance should I book a flight to Charleston?

We recommend purchasing flights from Des Moines to Charleston 35 days ahead of your departure date because this is when momondo users tend to see the best flight rates. On average, our users have found flights to Charleston for $394. In the past 72 hours, momondo users found flights from Des Moines to Charleston for as low as $233.

How have Des Moines to Charleston flight prices changed over time?

As of December 2024, prices for Des Moines to Charleston flights are approximately 24% cheaper when compared to flights at the same time last year.

When to book flights from Des Moines to Charleston

Are you open to changing your travel dates? Check out the ideal times to fly from Des Moines to Charleston according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Des Moines to Charleston (DSM to CHS) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Charleston

Best Price Found

$318

Fastest flight time

4h 30m

Direct flights

None

Airports in Charleston

1 airport
The best one-way flight to Charleston from Des Moines in the past 72 hours is $318. The best round-trip flight deal from Des Moines to Charleston found on momondo in the last 72 hours is $278.
The fastest flight from Des Moines to Charleston takes 4h 30m
There are no direct flights from Des Moines to Charleston. Popular non-direct route for this connection is Des Moines Airport - Charleston Airport.
There is 1 airport near Charleston: Charleston (CHS)

  • How far is Des Moines to Charleston by plane?

    The distance between Des Moines and Charleston is about 966.2 mi. Flights usually cover this in 4h 30m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Des Moines Airport to Charleston Airport?

    Prices for flights from Des Moines Airport to Charleston Airport were last updated today.

  • How many operators does momondo search for flights from Des Moines Airport to Charleston Airport?

  • How old do you have to be to fly from Des Moines Airport to Charleston Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Des Moines Airport to Charleston Airport.

  • What documentation or ID do you need to fly to Charleston Airport?

    The travel and health documents required for your trip to Charleston Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Charleston Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular airline from Des Moines to Charleston?


Best airlines flying from Des Moines to Charleston

Compare and see reviews for airlines that fly from Des Moines to Charleston with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $258Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights
DeltaPriceFrom $280Free CancellationRating
8.0
8,560 reviews
Search Delta flights
United AirlinesPriceFrom $306Free CancellationRating
7.4
9,001 reviews
Search United Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Charleston?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Des Moines to Charleston. momondo saves you time and could save you money on your trip.

Can I find flights from Des Moines to Charleston with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Des Moines to Charleston flights to just show those with flexible booking policies.

How can momondo help me find flights from Des Moines to Charleston?

momondo helps you find the best flight between Des Moines and Charleston by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Des Moines to Charleston right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Des Moines to Charleston flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.


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