What is the cheapest airline that flies from Des Moines to Buffalo?

United Airlines, Delta, and American Airlines are the most popular carriers operating from Des Moines to Buffalo

What airlines fly to Buffalo?

American Airlines, Delta and United Airlines are the top three most popular airlines that fly to Buffalo from Des Moines according to our data. American Airlines is the first choice among our users, with 42% of people opting to fly with this airline when traveling to Buffalo. Keep in mind that there are 3 different airlines that fly to Buffalo on a routine basis, so you have a few additional options to choose from.

When did momondo last update prices for flights from Des Moines Airport to Buffalo Airport?

Prices for flights from Des Moines Airport to Buffalo Airport were last updated today.

How many operators does momondo search for flights from Des Moines Airport to Buffalo Airport?

As of January 2025, there are 3 operators available to choose from for flights from Des Moines Airport to Buffalo Airport.

How old do you have to be to fly from Des Moines Airport to Buffalo Airport?

The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Des Moines Airport to Buffalo Airport.

What documentation or ID do you need to fly to Buffalo Airport?

The travel and health documents required for your trip to Buffalo Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Buffalo Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

$195 Cheap Flights from Des Moines to Buffalo in 2025

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Find the cheapest flights from Des Moines to Buffalo

Round-tripOne-way

Cheap round-trip flights

These are some of the best round-trip flight deals from Des Moines to Buffalo that have been recently found on momondo from popular airlines, departing in the coming months.

Cheap one-way flights

Flying one-way? These are some of the best deals recently discovered on momondo for flights from Des Moines to Buffalo.

Cheap last minute flights

Planning a quick getaway from Des Moines to Buffalo? These are the last-minute flight deals available now.

Cheap direct flights

If you prefer a non-stop journey, check out our latest direct flight deals to Buffalo, so you can enjoy a seamless trip without layovers.

Cheap bus & train deals from Des Moines to Buffalo

Find recent round-trip train or bus tickets from Des Moines to Buffalo.

All round-trip flight deals from Des Moines to Buffalo

The cheapest plane tickets from Des Moines to Buffalo found on KAYAK recently.

7:05 am - 1:35 pmDSM-BUF

5h 30m1 stop

6:22 am - 9:49 amBUF-DSM

4h 27m1 stop

$362Delta

Find Deal

qua, fev 5 - dom, fev 9

8:00 am - 6:33 pmDSM-BUF

9h 33m2 stops

7:00 am - 10:38 amBUF-DSM

4h 38m1 stop

$367United Airlines

Find Deal

qua, fev 5 - dom, fev 9

8:00 am - 6:33 pmDSM-BUF

9h 33m2 stops

6:00 am - 2:44 pmBUF-DSM

9h 44m2 stops

$372United Airlines

Find Deal

qua, fev 5 - dom, fev 9

7:25 am - 3:24 pmDSM-BUF

6h 59m1 stop

6:08 am - 12:21 pmBUF-DSM

7h 13m2 stops

$377American Airlines

Find Deal

sex, fev 21 - seg, fev 24

5:14 pm - 11:01 pmDSM-BUF

4h 47m1 stop

6:00 am - 10:40 amBUF-DSM

5h 40m1 stop

$388Delta

Find Deal

sex, fev 21 - seg, fev 24

7:25 am - 10:43 pmDSM-BUF

14h 18m1 stop

6:08 am - 2:46 pmBUF-DSM

9h 38m2 stops

$410American Airlines

Find Deal

sex, fev 21 - seg, fev 24

5:00 pm - 10:59 pmDSM-BUF

4h 59m1 stop

6:00 am - 10:14 amBUF-DSM

5h 14m1 stop

$423Delta

Find Deal

qua, jun 4 - dom, jun 8

12:57 pm - 10:43 pmDSM-BUF

8h 46m2 stops

6:08 am - 12:21 pmBUF-DSM

7h 13m2 stops

$432American Airlines

Find Deal

sex, fev 21 - seg, fev 24

11:25 am - 11:26 pmDSM-BUF

11h 01m2 stops

7:00 am - 10:29 amBUF-DSM

4h 29m1 stop

$539United Airlines

Find Deal

qua, jun 4 - dom, jun 8

2:52 pm - 12:20 amDSM-BUF

8h 28m2 stops

5:36 am - 12:19 pmBUF-DSM

7h 43m1 stop

$863American Airlines

Find Deal

sex, mar 14 - dom, mar 16

3:25 pm - 9:09 pmDSM-BUF

4h 44m1 stop

$467United Airlines

Find Deal

sex, mar 14

7:20 am - 2:10 pmDSM-BUF

5h 50m1 stop

$480Delta

Find Deal

sex, mar 14

2:52 pm - 12:20 amDSM-BUF

8h 28m2 stops

$565American Airlines

Find Deal

sex, mar 14

2:52 pm - 12:20 amDSM-BUF

8h 28m2 stops

$651American Airlines

Find Deal

sex, mar 14

Delta flights from Des Moines to Buffalo

Our best Delta deals on Des Moines to Buffalo flight tickets

Delta

Feb 5

DSM7:05 amDes Moines

5h 30m

1 stop

BUF1:35 pmBuffalo

Feb 9

BUF6:22 amBuffalo

4h 27m

1 stop

DSM9:49 amDes Moines

$362

Find similar

Delta

Feb 21

DSM5:14 pmDes Moines

4h 47m

1 stop

BUF11:01 pmBuffalo

Feb 24

BUF6:00 amBuffalo

5h 40m

1 stop

DSM10:40 amDes Moines

$388

Find similar

Delta

Jun 4

DSM5:00 pmDes Moines

4h 59m

1 stop

BUF10:59 pmBuffalo

Jun 8

BUF6:00 amBuffalo

5h 14m

1 stop

DSM10:14 amDes Moines

$423

Find similar

United Airlines flights from Des Moines to Buffalo

Our best United Airlines deals on Des Moines to Buffalo flight tickets

United Airlines

Feb 5

DSM8:00 amDes Moines

9h 33m

2 stops

BUF6:33 pmBuffalo

Feb 9

BUF7:00 amBuffalo

4h 38m

1 stop

DSM10:38 amDes Moines

$367

Find similar

United Airlines

Feb 5

DSM8:00 amDes Moines

9h 33m

2 stops

BUF6:33 pmBuffalo

Feb 9

BUF6:00 amBuffalo

9h 44m

2 stops

DSM2:44 pmDes Moines

$372

Find similar

United Airlines

Jun 4

DSM11:25 amDes Moines

11h 01m

2 stops

BUF11:26 pmBuffalo

Jun 8

BUF7:00 amBuffalo

4h 29m

1 stop

DSM10:29 amDes Moines

$539

Find similar

How to get the cheapest flight ticket from Des Moines to Buffalo

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to Buffalo?

If you aren’t able to travel during the month of November, then book flights to Buffalo from Des Moines during September instead. Flights to Buffalo in September, while not as cheap as those in November, still average around $341.

What is the cheapest day to depart on your flight to Buffalo?

Our data shows that Tuesday is the least expensive day to fly to Buffalo. Tickets to fly out on this day can be as low as $321. Flights from Des Moines to Buffalo on a Friday will generally be more expensive and average around $497. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

What is the cheapest time of day to depart on your flight to Buffalo?

In the morning is the cheapest time of day to fly from Des Moines to Buffalo when you can find flight prices for as low as $356. Flying to Buffalo in the morning is an ideal time because this is during off-peak travel hours. In the afternoon is when there is more demand to fly to Buffalo, so prices are often more expensive at around $452 per ticket.

When to book flights from Des Moines to Buffalo

Are you open to changing your travel dates? Check out the ideal times to fly from Des Moines to Buffalo according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Des Moines to Buffalo (DSM to BUF) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Buffalo

Best Price Found	$467
Fastest flight time	4h 11m
Direct flights	None
Airports in Buffalo	1 airport

The best one-way flight to Buffalo from Des Moines in the past 72 hours is $467. The best round-trip flight deal from Des Moines to Buffalo found on momondo in the last 72 hours is $362.

The fastest flight from Des Moines to Buffalo takes 4h 11m

There are no direct flights from Des Moines to Buffalo. Popular non-direct route for this connection is Des Moines Airport - Buffalo Airport.

There is 1 airport near Buffalo: Buffalo (BUF)

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How far is Des Moines to Buffalo by plane?
The straight-line distance from Des Moines to Buffalo is 758.3 mi. Typically, this will take 4h 11m by plane in normal conditions.
When did momondo last update prices for flights from Des Moines Airport to Buffalo Airport?
Prices for flights from Des Moines Airport to Buffalo Airport were last updated today.
How many operators does momondo search for flights from Des Moines Airport to Buffalo Airport?
As of January 2025, there are 3 operators available to choose from for flights from Des Moines Airport to Buffalo Airport.
How old do you have to be to fly from Des Moines Airport to Buffalo Airport?
The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Des Moines Airport to Buffalo Airport.
What documentation or ID do you need to fly to Buffalo Airport?
The travel and health documents required for your trip to Buffalo Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Buffalo Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.
What is the most popular airline from Des Moines to Buffalo?
momondo data reveals that the most frequently booked airline on the route from Des Moines to Buffalo is American Airlines, representing 43% of all bookings. The subsequent popular airlines are Delta at 41% and United Airlines at 17%.

Best airlines flying from Des Moines to Buffalo

Compare and see reviews for airlines that fly from Des Moines to Buffalo with momondo

Airline	Rating	Free Cancellation	Price
Delta	PriceFrom $196	Free Cancellation	Rating 8.0 8,512 reviews	Search Delta flights
American Airlines	PriceFrom $276	Free Cancellation	Rating 7.2 10,000 reviews	Search American Airlines flights
United Airlines	PriceFrom $357	Free Cancellation	Rating 7.4 8,975 reviews	Search United Airlines flights

Batavia

Williamsville

Amherst

Cheektowaga

Tonawanda

Lockport

West Seneca

East Aurora

Orchard Park

Grand Island

Bowmansville

Eden

Angola

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Buffalo?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Des Moines to Buffalo for you.

Can I find flights from Des Moines to Buffalo with flexible booking policies on momondo?

momondo does allow users to show only those flights to Buffalo from Des Moines which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Des Moines to Buffalo?

momondo provides multiple filters to help you find the best flight to Buffalo from Des Moines. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Des Moines to Buffalo right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Buffalo, momondo offers a useful price alert feature which will track prices for flights to Buffalo from Des Moines and alert you when they change.