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Cheap flights from St. Louis to Knoxville from $209

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from St. Louis to Knoxville departing on 12/20. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from St. Louis to Knoxville

Cheap round-trip flights

These are some of the best round-trip flight deals from St. Louis to Knoxville that have been recently found on momondo from popular airlines, departing in the coming months.

Cheap one-way flights

Flying one-way? These are some of the best deals recently discovered on momondo for flights from St. Louis to Knoxville.

Cheap last minute flights

Planning a quick getaway from St. Louis to Knoxville? These are the last-minute flight deals available now.

Cheap direct flights

If you prefer a non-stop journey, check out our latest direct flight deals to Knoxville, so you can enjoy a seamless trip without layovers.

Cheap bus & train deals from St. Louis to Knoxville

Find recent round-trip train or bus tickets from St. Louis to Knoxville.

All round-trip flight deals to Knoxville

The cheapest plane tickets to Knoxville found on KAYAK recently.
4:08 pm - 12:21 amSTL-TYS
7h 13m1 stop
10:58 am - 1:37 pmTYS-STL
3h 39m1 stop
$218American Airlines
Find Deal
Wed, Dec 18 - Wed, Dec 25
5:17 am - 11:32 amSTL-TYS
5h 15m1 stop
6:03 pm - 11:59 pmTYS-STL
6h 56m1 stop
$223American Airlines
Find Deal
Wed, Dec 4 - Wed, Dec 11
10:54 am - 6:40 pmSTL-TYS
6h 46m1 stop
6:30 am - 11:32 amTYS-STL
6h 02m1 stop
$228American Airlines
Find Deal
Thu, Jan 16 - Mon, Jan 20
5:30 pm - 10:32 pmSTL-TYS
4h 02m1 stop
6:38 pm - 11:43 pmTYS-STL
6h 05m1 stop
$233Delta
Find Deal
Sat, Dec 7 - Thu, Dec 12
4:27 pm - 11:31 pmSTL-TYS
6h 04m1 stop
4:44 pm - 3:21 pmTYS-STL
23h 37m2 stops
Thu, Dec 19 - Mon, Dec 23
5:03 am - 10:24 amSTL-TYS
4h 21m1 stop
5:53 am - 9:56 amTYS-STL
5h 03m1 stop
$293American Airlines
Find Deal
Fri, Dec 20 - Thu, Jan 2
4:27 pm - 11:31 pmSTL-TYS
6h 04m1 stop
9:40 pm - 6:41 pmTYS-STL
22h 01m3 stops
Thu, Dec 19 - Mon, Dec 23
11:20 am - 5:05 pmSTL-TYS
4h 45m1 stop
5:45 am - 3:34 pmTYS-STL
10h 49m2 stops
$377United Airlines
Find Deal
Sat, Dec 7 - Thu, Dec 12
5:30 pm - 10:36 pmSTL-TYS
4h 06m1 stop
5:45 am - 11:30 pmTYS-STL
18h 45m2 stops
$432United Airlines
Find Deal
Fri, Jan 17 - Mon, Jan 20
7:09 pm - 11:51 pmSTL-TYS
3h 42m1 stop
7:59 pm - 11:43 pmTYS-STL
4h 44m1 stop
$518Delta
Find Deal
Sun, Dec 8 - Thu, Dec 12
5:29 pm - 12:20 amSTL-TYS
5h 51m1 stop
$209American Airlines
Find Deal
Fri, Dec 20
5:05 pm - 11:50 pmSTL-TYS
5h 45m1 stop
$279Delta
Find Deal
Tue, Dec 3
9:50 am - 12:01 pmSTL-TYS
25h 11m3 stops
Fri, Dec 6
4:31 pm - 2:41 pmSTL-TYS
21h 10m1 stop
$337United Airlines
Find Deal
Tue, Dec 3
4:31 pm - 1:23 pmSTL-TYS
19h 52m2 stops
$342United Airlines
Find Deal
Tue, Dec 3
1:00 pm - 3:03 pmSTL-TYS
25h 03m2 stops
Sat, Nov 30
6:30 am - 11:43 amSTL-TYS
4h 13m1 stop
$354Delta
Find Deal
Mon, Dec 2
6:25 am - 11:59 pmSTL-TYS
16h 34m2 stops
$373United Airlines
Find Deal
Fri, Dec 20
5:40 pm - 8:02 pmSTL-TYS
25h 22m2 stops
$398United Airlines
Find Deal
Fri, Dec 6
6:34 pm - 11:58 pmSTL-TYS
4h 24m1 stop
$444American Airlines
Find Deal
Sat, Nov 30
4:03 pm - 12:19 amSTL-TYS
7h 16m1 stop
6:04 pm - 11:58 pmTYS-STL
6h 54m1 stop
$288American Airlines
Find Deal
Fri, Nov 22 - Sun, Nov 24
6:34 pm - 11:58 pmSTL-TYS
4h 24m1 stop
8:08 pm - 11:58 pmTYS-STL
4h 50m1 stop
$533American Airlines
Find Deal
Fri, Nov 22 - Mon, Nov 25
11:20 am - 11:59 pmSTL-TYS
11h 39m2 stops
9:25 am - 4:38 pmTYS-STL
8h 13m1 stop
$710United Airlines
Find Deal
Fri, Nov 22 - Mon, Nov 25
1:05 pm - 11:59 pmSTL-TYS
9h 54m2 stops
7:00 am - 10:27 amTYS-STL
4h 27m1 stop
$750United Airlines
Find Deal
Fri, Nov 22 - Sun, Nov 24
9:50 am - 12:02 pmSTL-TYS
25h 12m3 stops
3:32 pm - 1:30 pmTYS-STL
22h 58m3 stops
$1,081
Find Deal
Fri, Nov 22 - Sun, Nov 24
11:20 am - 10:30 pmSTL-TYS
10h 10m2 stops
7:00 am - 3:58 pmTYS-STL
9h 58m2 stops
$2,171United Airlines
Find Deal
Fri, Nov 22 - Sun, Nov 24

American Airlines flights from St. Louis to Knoxville

Our best American Airlines deals on St. Louis to Knoxville flight tickets
American Airlines
Dec 18
STL4:08 pmLambert-St Louis
7h 13m
1 stop
TYS12:21 amKnoxville McGhee Tyson
Dec 25
TYS10:58 amKnoxville McGhee Tyson
3h 39m
1 stop
STL1:37 pmLambert-St Louis
American Airlines
Dec 4
STL5:17 amLambert-St Louis
5h 15m
1 stop
TYS11:32 amKnoxville McGhee Tyson
Dec 11
TYS6:03 pmKnoxville McGhee Tyson
6h 56m
1 stop
STL11:59 pmLambert-St Louis
American Airlines
Jan 16
STL10:54 amLambert-St Louis
6h 46m
1 stop
TYS6:40 pmKnoxville McGhee Tyson
Jan 20
TYS6:30 amKnoxville McGhee Tyson
6h 02m
1 stop
STL11:32 amLambert-St Louis

Delta flights from St. Louis to Knoxville

Our best Delta deals on St. Louis to Knoxville flight tickets
Delta
Dec 7
STL5:30 pmLambert-St Louis
4h 02m
1 stop
TYS10:32 pmKnoxville McGhee Tyson
Dec 12
TYS6:38 pmKnoxville McGhee Tyson
6h 05m
1 stop
STL11:43 pmLambert-St Louis
Delta
Nov 27
STL5:34 pmLambert-St Louis
5h 16m
1 stop
TYS11:50 pmKnoxville McGhee Tyson
Nov 30
TYS5:30 amKnoxville McGhee Tyson
4h 39m
1 stop
STL9:09 amLambert-St Louis
Delta
Dec 8
STL7:09 pmLambert-St Louis
3h 42m
1 stop
TYS11:51 pmKnoxville McGhee Tyson
Dec 12
TYS7:59 pmKnoxville McGhee Tyson
4h 44m
1 stop
STL11:43 pmLambert-St Louis

See travel insights to Knoxville from

How to get the cheapest flight ticket from St. Louis to Knoxville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly from St. Louis to Knoxville?

February. The cheapest time of year to fly to Knoxville from St. Louis is February. Most expensive is March

What is the cheapest day to depart St. Louis for Knoxville?

Thursday. The cheapest day of the week is typically Thursday. The most expensive is typically Sunday

When is the cheapest time to fly from St. Louis to Knoxville?

In the morning. St. Louis to Knoxville flights are approximately 22% more expensive at noon than in the morning

What is the cheapest St. Louis to Knoxville flight route?

Lambert-St Louis - Knoxville McGhee Tyson. Fly from Lambert-St Louis to Knoxville McGhee Tyson for the best St. Louis - Knoxville flight prices

How far in advance should you book St. Louis to Knoxville flights?

46 days before. The cheapest time to buy a flight from St. Louis to Knoxville is approximately 46 days to departure

Can stopping save me money on St. Louis to Knoxville flights?

You could potentially save up to 38% on your flight if you consider stops on a St. Louis to Knoxville flight.

How have St. Louis to Knoxville flight prices changed over time?

As of November 2024, prices for St. Louis to Knoxville flights are approximately 112% more expensive when compared to flights at the same time last year.

When to book flights from St. Louis to Knoxville

Are you open to changing your travel dates? Check out the ideal times to fly from St. Louis to Knoxville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap St. Louis to Knoxville (STL to TYS) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from St. Louis to Knoxville

Best Price Found

$209

Fastest flight time

3h 42m

Direct flights

None

Airports in Knoxville

1 airport
The best one-way flight to Knoxville from St. Louis in the past 72 hours is $209. The best round-trip flight deal from St. Louis to Knoxville found on momondo in the last 72 hours is $218.
The fastest flight from St. Louis to Knoxville takes 3h 42m
There are no direct flights from St. Louis to Knoxville. Popular non-direct route for this connection is Lambert-St Louis Airport - Knoxville McGhee Tyson Airport.
There is 1 airport near Knoxville: Knoxville McGhee Tyson (TYS)

  • How far is Lambert-St Louis to Knoxville McGhee Tyson by plane?

    Lambert-St Louis and Knoxville McGhee Tyson are 390.7 mi apart from one another. Flights usually cover this in 3h 42m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Lambert-St Louis Airport to Knoxville McGhee Tyson Airport?

    Prices for flights from Lambert-St Louis Airport to Knoxville McGhee Tyson Airport were last updated today.

  • How many operators does momondo search for flights from Lambert-St Louis Airport to Knoxville McGhee Tyson Airport?

  • How old do you have to be to fly from Lambert-St Louis Airport to Knoxville McGhee Tyson Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Lambert-St Louis Airport to Knoxville McGhee Tyson Airport.

  • What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?

    The required travel and health documents for your Knoxville McGhee Tyson Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Knoxville McGhee Tyson Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from St. Louis to Knoxville?


Best airlines flying from St. Louis to Knoxville

Compare and see reviews for airlines that fly from St. Louis to Knoxville with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $208Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights
DeltaPriceFrom $227Free CancellationRating
8.0
8,759 reviews
Search Delta flights
United AirlinesPriceFrom $265Free CancellationRating
7.4
9,173 reviews
Search United Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from St. Louis to Knoxville?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from St. Louis to Knoxville. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from St. Louis to Knoxville with flexible booking policies on momondo?

Yes. All flights to Knoxville from St. Louis on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from St. Louis to Knoxville?

momondo helps you find the best flight between St. Louis and Knoxville by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from St. Louis to Knoxville right now. Can momondo alert me if prices change?

If you are not ready to book a flight from St. Louis to Knoxville now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Knoxville and let you know when they change.


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