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Cheap flights from South Carolina to Des Moines from $65

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from South Carolina to Des Moines departing on 1/4. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from South Carolina to Des Moines

Cheap round-trip flights

These are some of the best round-trip flight deals from South Carolina to Des Moines that have been recently found on momondo from popular airlines, departing in the coming months.

Cheap one-way flights

Flying one-way? These are some of the best deals recently discovered on momondo for flights from South Carolina to Des Moines.

Cheap last minute flights

Planning a quick getaway from South Carolina to Des Moines? These are the last-minute flight deals available now.

Cheap direct flights

If you prefer a non-stop journey, check out our latest direct flight deals to Des Moines, so you can enjoy a seamless trip without layovers.

Cheap bus & train deals from South Carolina to Des Moines

Find recent round-trip train or bus tickets from South Carolina to Des Moines.

All round-trip flight deals to Des Moines

The cheapest plane tickets to Des Moines found on KAYAK recently.
7:10 pm - 4:07 pmCLT-DSM
21h 57m1 stop
5:07 pm - 1:19 pmDSM-CLT
19h 12m1 stop
$158Frontier
Find Deal
jue., dic. 12 - lun., dic. 16
3:56 pm - 9:57 amCLT-DSM
19h 01m1 stop
10:57 am - 3:00 pmDSM-CLT
27h 03m1 stop
$168Frontier
Find Deal
jue., ene. 9 - dom., ene. 12
5:44 pm - 9:46 pmCLT-DSM
5h 02m1 stop
3:20 pm - 9:31 pmDSM-CLT
5h 11m1 stop
$216United Airlines
Find Deal
vie., nov. 22 - lun., nov. 25
8:35 am - 1:33 pmCLT-DSM
5h 58m1 stop
10:26 am - 3:38 pmDSM-CLT
4h 12m1 stop
$254Delta
Find Deal
dom., nov. 24 - vie., nov. 29
6:50 am - 1:18 pmCAE-DSM
7h 28m1 stop
11:02 am - 5:56 pmDSM-CAE
5h 54m1 stop
$278American Airlines
Find Deal
mar., dic. 24 - sáb., ene. 4
11:54 am - 1:40 pmCLT-DSM
2h 46mnonstop
11:00 am - 6:59 pmDSM-CLT
6h 59m1 stop
$283American Airlines
Find Deal
dom., nov. 24 - vie., nov. 29
7:05 am - 1:33 pmCLT-DSM
7h 28m1 stop
10:26 am - 3:38 pmDSM-CLT
4h 12m1 stop
$289Delta
Find Deal
mar., nov. 26 - mar., dic. 3
5:44 pm - 9:46 pmCLT-DSM
5h 02m1 stop
11:25 am - 11:41 pmDSM-CLT
11h 16m2 stops
$291United Airlines
Find Deal
vie., nov. 22 - lun., nov. 25
5:29 am - 5:44 pmCLT-DSM
13h 15m3 stops
2:21 pm - 6:58 amDSM-CLT
15h 37m1 stop
vie., nov. 22 - lun., nov. 25
5:29 am - 5:44 pmCLT-DSM
13h 15m3 stops
7:40 am - 8:27 pmDSM-CLT
11h 47m2 stops
vie., nov. 22 - lun., nov. 25
6:40 pm - 6:18 pmCLT-DSM
24h 38m1 stop
$65Frontier
Find Deal
sáb., ene. 4
7:10 pm - 4:07 pmCLT-DSM
21h 57m1 stop
$85Frontier
Find Deal
jue., dic. 5
5:07 pm - 10:25 pmCLT-DSM
6h 18m1 stop
$108Delta
Find Deal
jue., ene. 2
11:54 am - 1:40 pmCLT-DSM
2h 46mnonstop
$137American Airlines
Find Deal
jue., nov. 28
5:25 pm - 9:52 pmCLT-DSM
5h 27m1 stop
$143United Airlines
Find Deal
mié., ene. 1
6:00 am - 10:32 amSAV-DSM
5h 32m1 stop
$148Delta
Find Deal
dom., nov. 24
6:44 am - 5:22 pmCHS-DSM
11h 38m2 stops
$153American Airlines
Find Deal
jue., nov. 28
1:00 pm - 11:00 pmSAV-DSM
11h 00m2 stops
$153Southwest
Find Deal
dom., nov. 24
6:05 pm - 9:30 pmCLT-DSM
4h 25m1 stop
$181Southwest
Find Deal
mar., feb. 4
6:00 am - 2:23 pmCLT-DSM
9h 23m2 stops
$186United Airlines
Find Deal
jue., nov. 28
11:54 am - 1:40 pmCLT-DSM
2h 46mnonstop
2:00 pm - 5:15 pmDSM-CLT
2h 15mnonstop
$531American Airlines
Find Deal
vie., nov. 8 - dom., nov. 10
6:20 pm - 11:58 pmCLT-DSM
6h 38m1 stop
6:55 am - 10:12 amDSM-CLT
2h 17mnonstop
$541American Airlines
Find Deal
vie., nov. 8 - dom., nov. 10
10:50 am - 2:23 pmCLT-DSM
4h 33m1 stop
3:20 pm - 9:31 pmDSM-CLT
5h 11m1 stop
$550United Airlines
Find Deal
vie., nov. 8 - dom., nov. 10
10:50 am - 8:34 pmCLT-DSM
10h 44m2 stops
3:20 pm - 9:31 pmDSM-CLT
5h 11m1 stop
$555United Airlines
Find Deal
vie., nov. 8 - dom., nov. 10
6:00 am - 2:23 pmCLT-DSM
9h 23m2 stops
6:00 am - 4:48 pmDSM-CLT
9h 48m2 stops
$560United Airlines
Find Deal
vie., nov. 8 - dom., nov. 10
7:45 am - 11:59 amGSP-DSM
5h 14m1 stop
5:09 pm - 11:37 pmDSM-GSP
5h 28m1 stop
$606American Airlines
Find Deal
mié., nov. 6 - mar., nov. 12
2:32 pm - 9:53 pmGSP-DSM
8h 21m2 stops
5:41 pm - 11:56 pmDSM-GSP
5h 15m1 stop
$611American Airlines
Find Deal
mié., nov. 6 - mar., nov. 12
2:05 pm - 9:25 pmGSP-DSM
8h 20m2 stops
6:50 am - 8:05 pmDSM-GSP
12h 15m2 stops
$616Southwest
Find Deal
mié., nov. 6 - mar., nov. 12
5:29 am - 6:17 pmCLT-DSM
13h 48m2 stops
10:24 am - 10:47 amDSM-CLT
23h 23m3 stops
vie., nov. 8 - dom., nov. 10
7:01 am - 1:40 pmAGS-DSM
7h 39m1 stop
2:00 pm - 7:56 pmDSM-AGS
4h 56m1 stop
$782American Airlines
Find Deal
vie., nov. 8 - dom., nov. 10
8:28 pm - 10:01 pmCLT-DSM
2h 33mnonstop
6:55 am - 10:12 amDSM-CLT
2h 17mnonstop
$308American Airlines
Find Deal
dom., nov. 24 - vie., nov. 29
9:30 pm - 10:59 pmCLT-DSM
2h 29mnonstop
6:26 am - 10:00 amDSM-CLT
2h 34mnonstop
$336American Airlines
Find Deal
mié., ene. 1 - dom., ene. 5
11:54 am - 1:40 pmCLT-DSM
2h 46mnonstop
2:02 pm - 5:24 pmDSM-CLT
2h 22mnonstop
$343American Airlines
Find Deal
mié., dic. 4 - mié., dic. 11
11:44 am - 1:27 pmCLT-DSM
2h 43mnonstop
6:27 am - 9:59 amDSM-CLT
2h 32mnonstop
$362American Airlines
Find Deal
mié., dic. 11 - dom., dic. 15
8:20 pm - 9:49 pmCLT-DSM
2h 29mnonstop
6:27 am - 9:59 amDSM-CLT
2h 32mnonstop
$381American Airlines
Find Deal
jue., dic. 12 - lun., dic. 16
9:30 pm - 10:59 pmCLT-DSM
2h 29mnonstop
6:26 am - 10:00 amDSM-CLT
2h 34mnonstop
$390American Airlines
Find Deal
jue., dic. 26 - lun., dic. 30
11:54 am - 1:40 pmCLT-DSM
2h 46mnonstop
6:55 am - 10:12 amDSM-CLT
2h 17mnonstop
$405American Airlines
Find Deal
jue., nov. 28 - sáb., nov. 30
11:54 am - 1:40 pmCLT-DSM
2h 46mnonstop
2:04 pm - 5:19 pmDSM-CLT
2h 15mnonstop
$432American Airlines
Find Deal
jue., nov. 28 - lun., dic. 2
9:30 pm - 10:59 pmCLT-DSM
2h 29mnonstop
6:26 am - 10:00 amDSM-CLT
2h 34mnonstop
$456American Airlines
Find Deal
jue., dic. 19 - lun., dic. 23
8:28 pm - 10:01 pmCLT-DSM
2h 33mnonstop
1:59 pm - 5:14 pmDSM-CLT
2h 15mnonstop
$463American Airlines
Find Deal
mar., nov. 19 - mié., nov. 20

Delta flights from South Carolina to Des Moines

Our best Delta deals on South Carolina to Des Moines flight tickets
Delta
Nov 24
CLT8:35 amCharlotte Douglas
5h 58m
1 stop
DSM1:33 pmDes Moines
Nov 29
DSM10:26 amDes Moines
4h 12m
1 stop
CLT3:38 pmCharlotte Douglas
Delta
Nov 26
CLT7:05 amCharlotte Douglas
7h 28m
1 stop
DSM1:33 pmDes Moines
Dec 3
DSM10:26 amDes Moines
4h 12m
1 stop
CLT3:38 pmCharlotte Douglas
Delta
Dec 19
CLT6:03 amCharlotte Douglas
6h 42m
1 stop
DSM11:45 amDes Moines
Dec 23
DSM5:35 pmDes Moines
4h 53m
1 stop
CLT11:28 pmCharlotte Douglas

American Airlines flights from South Carolina to Des Moines

Our best American Airlines deals on South Carolina to Des Moines flight tickets
American Airlines
Dec 24
CAE6:50 amColumbia Metropolitan
7h 28m
1 stop
DSM1:18 pmDes Moines
Jan 4
DSM11:02 amDes Moines
5h 54m
1 stop
CAE5:56 pmColumbia Metropolitan
American Airlines
Nov 24
CLT11:54 amCharlotte Douglas
2h 46m
DSM1:40 pmDes Moines
Nov 29
DSM11:00 amDes Moines
6h 59m
1 stop
CLT6:59 pmCharlotte Douglas
American Airlines
Nov 24
CLT8:28 pmCharlotte Douglas
2h 33m
DSM10:01 pmDes Moines
Nov 29
DSM6:55 amDes Moines
2h 17m
CLT10:12 amCharlotte Douglas

How to get the cheapest flight ticket from South Carolina to Des Moines

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies to Des Moines from South Carolina?

Delta. Delta and American Airlines are the most popular carriers operating from South Carolina to Des Moines

What is the cheapest South Carolina to Des Moines flight route?

Charlotte Douglas - Des Moines. Fly from Charlotte Douglas to Des Moines for the best South Carolina - Des Moines flight prices

Can stopping save me money on South Carolina to Des Moines flights?

You could potentially save up to 52% on your flight if you consider stops on a South Carolina to Des Moines flight.

Cheap South Carolina to Des Moines flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from South Carolina to Des Moines

Best Price Found

$65

Fastest flight time

2h 29m

Direct flights

Every day

Airports in Des Moines

1 airport
The best one-way flight to Des Moines from South Carolina in the past 72 hours is $65. The best round-trip flight deal from South Carolina to Des Moines found on momondo in the last 72 hours is $158.
The fastest flight from South Carolina to Des Moines takes 2h 29m
Direct flights go from South Carolina to Des Moines every day.
There is 1 airport near Des Moines: Des Moines (DSM)

  • When did momondo last update prices for flights from South Carolina to Des Moines Airport?

    Prices for flights from South Carolina to Des Moines Airport refresh daily.

  • How many operators does momondo search for flights from South Carolina to Des Moines Airport?

  • How old do you have to be to fly from South Carolina to Des Moines Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from South Carolina to Des Moines Airport.

  • What documentation or ID do you need to fly to Des Moines Airport?

    The travel and health documents you'll need for your trip to Des Moines Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Des Moines Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.


Best airlines flying from South Carolina to Des Moines

Compare and see reviews for airlines that fly from South Carolina to Des Moines with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $189Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights
DeltaPriceFrom $198Free CancellationRating
8.0
8,830 reviews
Search Delta flights

Why use momondo?

Why should I use momondo to find a flight deal from South Carolina to Des Moines?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Des Moines from South Carolina.

Can I find flights from South Carolina to Des Moines with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for South Carolina to Des Moines flights to just show those with flexible booking policies.

How can momondo help me find flights from South Carolina to Des Moines?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from South Carolina to Des Moines.

I’m not ready to book a flight from South Carolina to Des Moines right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of South Carolina to Des Moines flights. All you need is a valid email address and we will do the rest; it is that quick and easy.


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