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Cheap flights from Santa Ana to Knoxville from $156

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Santa Ana to Knoxville departing on 1/23. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Santa Ana to Knoxville

Cheap round-trip flights

These are some of the best round-trip flight deals from Santa Ana to Knoxville that have been recently found on momondo from popular airlines, departing in the coming months.

Cheap one-way flights

Flying one-way? These are some of the best deals recently discovered on momondo for flights from Santa Ana to Knoxville.

Cheap last minute flights

Planning a quick getaway from Santa Ana to Knoxville? These are the last-minute flight deals available now.

Cheap direct flights

If you prefer a non-stop journey, check out our latest direct flight deals to Knoxville, so you can enjoy a seamless trip without layovers.

Cheap bus & train deals from Santa Ana to Knoxville

Find recent round-trip train or bus tickets from Santa Ana to Knoxville.

All round-trip flight deals to Knoxville

The cheapest plane tickets to Knoxville found on KAYAK recently.
6:45 am - 11:08 pmSNA-TYS
13h 23m1 stop
1:36 pm - 2:07 pmTYS-SNA
27h 31m3 stops
Fri, Feb 21 - Tue, Feb 25
7:45 am - 7:25 pmSNA-TYS
8h 40m1 stop
5:28 am - 11:48 amTYS-SNA
9h 20m1 stop
$288American Airlines
Find Deal
Sat, Feb 15 - Sat, Feb 22
7:45 am - 5:35 pmSNA-TYS
6h 50m1 stop
5:28 am - 11:32 amTYS-SNA
9h 04m2 stops
$293American Airlines
Find Deal
Sat, Feb 15 - Sat, Feb 22
1:33 pm - 11:54 pmSNA-TYS
7h 21m2 stops
5:28 am - 11:32 amTYS-SNA
9h 04m2 stops
$298American Airlines
Find Deal
Sat, Feb 15 - Sat, Feb 22
9:20 pm - 9:12 amSNA-TYS
8h 52m1 stop
5:30 am - 11:45 amTYS-SNA
9h 15m1 stop
$313Delta
Find Deal
Mon, Mar 24 - Tue, Apr 1
9:20 pm - 9:12 amSNA-TYS
8h 52m1 stop
5:30 am - 12:11 pmTYS-SNA
9h 41m2 stops
$318Delta
Find Deal
Mon, Mar 24 - Wed, Apr 2
12:27 pm - 11:30 pmSNA-TYS
8h 03m1 stop
9:00 am - 2:10 pmTYS-SNA
8h 10m1 stop
$378United Airlines
Find Deal
Tue, Mar 25 - Tue, Apr 1
12:27 pm - 11:30 pmSNA-TYS
8h 03m1 stop
9:00 am - 5:33 pmTYS-SNA
11h 33m2 stops
$383United Airlines
Find Deal
Tue, Mar 25 - Tue, Apr 1
6:45 am - 11:52 pmSNA-TYS
14h 07m2 stops
12:32 pm - 9:57 pmTYS-SNA
12h 25m2 stops
$488Alaska Airlines
Find Deal
Wed, Mar 26 - Wed, Apr 2
6:45 am - 11:52 pmSNA-TYS
14h 07m2 stops
11:07 am - 8:45 amTYS-SNA
24h 38m2 stops
$693Alaska Airlines
Find Deal
Thu, Mar 6 - Sun, Mar 9
6:45 am - 9:18 pmSNA-TYS
11h 33m2 stops
Thu, Jan 23
3:00 pm - 2:00 pmSNA-TYS
20h 00m2 stops
Thu, Jan 23
3:00 pm - 2:28 pmSNA-TYS
20h 28m3 stops
Thu, Jan 23
3:00 pm - 2:28 pmSNA-TYS
20h 28m3 stops
Thu, Jan 23
9:50 am - 6:53 pmSNA-TYS
6h 03m1 stop
$194Frontier
Find Deal
Thu, Jan 2
9:50 am - 6:53 pmSNA-TYS
6h 03m1 stop
$234Frontier
Find Deal
Thu, Jan 2
9:20 pm - 9:23 amSNA-TYS
9h 03m1 stop
$245Delta
Find Deal
Thu, Jan 23
6:45 am - 5:20 pmSNA-TYS
7h 35m1 stop
$317American Airlines
Find Deal
Wed, Jan 1
7:50 am - 6:11 pmSNA-TYS
7h 21m1 stop
$402American Airlines
Find Deal
Mon, Dec 23
6:45 am - 6:37 pmSNA-TYS
8h 52m1 stop
$489Delta
Find Deal
Thu, Jan 16
7:50 am - 6:11 pmSNA-TYS
7h 21m1 stop
5:14 am - 9:38 amTYS-SNA
7h 24m1 stop
$1,843American Airlines
Find Deal
Thu, Dec 19 - Sat, Jan 4
6:45 am - 7:27 pmSNA-TYS
9h 42m2 stops
5:14 am - 9:38 amTYS-SNA
7h 24m1 stop
$1,848American Airlines
Find Deal
Thu, Dec 19 - Sat, Jan 4
5:30 pm - 3:01 pmSNA-TYS
18h 31m2 stops
8:45 am - 1:06 pmTYS-SNA
7h 21m1 stop
$2,139United Airlines
Find Deal
Thu, Dec 19 - Sat, Jan 4
6:45 am - 7:27 pmSNA-TYS
9h 42m2 stops
11:38 am - 5:57 pmTYS-SNA
9h 19m2 stops
$2,235American Airlines
Find Deal
Thu, Dec 19 - Sat, Jan 4
5:30 pm - 3:01 pmSNA-TYS
18h 31m2 stops
10:45 am - 9:08 pmTYS-SNA
13h 23m2 stops
$2,472United Airlines
Find Deal
Thu, Dec 19 - Sat, Jan 4

American Airlines flights from Santa Ana to Knoxville

Our best American Airlines deals on Santa Ana to Knoxville flight tickets
American Airlines
Feb 15
SNA7:45 amSanta Ana J. Wayne/Orange Cnty
8h 40m
1 stop
TYS7:25 pmKnoxville McGhee Tyson
Feb 22
TYS5:28 amKnoxville McGhee Tyson
9h 20m
1 stop
SNA11:48 amSanta Ana J. Wayne/Orange Cnty
American Airlines
Feb 15
SNA7:45 amSanta Ana J. Wayne/Orange Cnty
6h 50m
1 stop
TYS5:35 pmKnoxville McGhee Tyson
Feb 22
TYS5:28 amKnoxville McGhee Tyson
9h 04m
2 stops
SNA11:32 amSanta Ana J. Wayne/Orange Cnty
American Airlines
Feb 15
SNA1:33 pmSanta Ana J. Wayne/Orange Cnty
7h 21m
2 stops
TYS11:54 pmKnoxville McGhee Tyson
Feb 22
TYS5:28 amKnoxville McGhee Tyson
9h 04m
2 stops
SNA11:32 amSanta Ana J. Wayne/Orange Cnty

Alaska Airlines flights from Santa Ana to Knoxville

Our best Alaska Airlines deals on Santa Ana to Knoxville flight tickets
Alaska Airlines
Mar 26
SNA6:45 amSanta Ana J. Wayne/Orange Cnty
14h 07m
2 stops
TYS11:52 pmKnoxville McGhee Tyson
Apr 2
TYS12:32 pmKnoxville McGhee Tyson
12h 25m
2 stops
SNA9:57 pmSanta Ana J. Wayne/Orange Cnty
Alaska Airlines
Mar 6
SNA6:45 amSanta Ana J. Wayne/Orange Cnty
14h 07m
2 stops
TYS11:52 pmKnoxville McGhee Tyson
Mar 9
TYS11:07 amKnoxville McGhee Tyson
24h 38m
2 stops
SNA8:45 amSanta Ana J. Wayne/Orange Cnty
Alaska Airlines
Mar 6
SNA6:45 amSanta Ana J. Wayne/Orange Cnty
14h 07m
2 stops
TYS11:52 pmKnoxville McGhee Tyson
Mar 9
TYS11:07 amKnoxville McGhee Tyson
24h 38m
2 stops
SNA8:45 amSanta Ana J. Wayne/Orange Cnty

See travel insights to Knoxville from

How to get the cheapest flight ticket from Santa Ana to Knoxville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Knoxville?

The month of August is, on average, the cheapest month to fly to Knoxville from Santa Ana, with most prices found around $358. If you aren’t able to travel during the month of August, then book flights to Knoxville from Santa Ana during September instead. Flights to Knoxville in September, while not as cheap as those in August, still average around $374.

What is the cheapest day to depart on your flight to Knoxville?

The cheapest day to depart from Santa Ana to Knoxville is on a Saturday. Travelers who choose to depart for Knoxville on a Saturday will often find tickets for as low as $387. When flying out on a Sunday, the most expensive travel day of the week, you can expect to see flight prices from Santa Ana to Knoxville for around $552.

What is the cheapest time of day to depart on your flight to Knoxville?

In the afternoon is the cheapest time of day to fly from Santa Ana to Knoxville when you can find flight prices for as low as $399. Flying to Knoxville in the afternoon is an ideal time because this is during off-peak travel hours. In contrast, the most expensive time of day to depart to Knoxville is in the evening when prices are around $443.

How far in advance should I book a flight to Knoxville?

We recommend purchasing flights from Santa Ana to Knoxville 40 days ahead of your departure date because this is when momondo users tend to see the best flight rates. On average, our users have found flights to Knoxville for $486. Keep in mind that you might also find cheap flights to Knoxville outside of this time window. In fact, momondo users recently found flights from Santa Ana to Knoxville for $278.

Can stopping save me money on Santa Ana to Knoxville flights?

You could potentially save up to 19% on your flight if you consider stops on a Santa Ana to Knoxville flight.

How have Santa Ana to Knoxville flight prices changed over time?

As of December 2024, prices for Santa Ana to Knoxville flights are approximately 18% more expensive when compared to flights at the same time last year.

When to book flights from Santa Ana to Knoxville

Are you open to changing your travel dates? Check out the ideal times to fly from Santa Ana to Knoxville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Santa Ana to Knoxville (SNA to TYS) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santa Ana to Knoxville

Best Price Found

$156

Fastest flight time

5h 51m

Direct flights

None

Airports in Knoxville

1 airport
The best one-way flight to Knoxville from Santa Ana in the past 72 hours is $156. The best round-trip flight deal from Santa Ana to Knoxville found on momondo in the last 72 hours is $287.
The fastest flight from Santa Ana to Knoxville takes 5h 51m
There are no direct flights from Santa Ana to Knoxville. Popular non-direct route for this connection is Santa Ana J. Wayne/Orange Cnty Airport - Knoxville McGhee Tyson Airport.
There is 1 airport near Knoxville: Knoxville McGhee Tyson (TYS)

  • How far is Santa Ana J. Wayne/Orange Cnty to Knoxville McGhee Tyson by plane?

    Santa Ana J. Wayne/Orange Cnty and Knoxville McGhee Tyson are 1919.8 mi apart from one another. 5h 51m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Santa Ana J. Wayne/Orange Cnty Airport to Knoxville McGhee Tyson Airport?

    Prices for flights from Santa Ana J. Wayne/Orange Cnty Airport to Knoxville McGhee Tyson Airport are updated daily.

  • How many operators does momondo search for flights from Santa Ana J. Wayne/Orange Cnty Airport to Knoxville McGhee Tyson Airport?

  • How old do you have to be to fly from Santa Ana J. Wayne/Orange Cnty Airport to Knoxville McGhee Tyson Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Santa Ana J. Wayne/Orange Cnty Airport to Knoxville McGhee Tyson Airport.

  • What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?

    The necessary travel and health documents for your Knoxville McGhee Tyson Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Santa Ana to Knoxville?


Best airlines flying from Santa Ana to Knoxville

Compare and see reviews for airlines that fly from Santa Ana to Knoxville with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $228Free CancellationRating
7.4
9,055 reviews
Search United Airlines flights
DeltaPriceFrom $281Free CancellationRating
8.0
8,604 reviews
Search Delta flights
American AirlinesPriceFrom $286Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Santa Ana to Knoxville?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Santa Ana to Knoxville for you.

Can I find flights from Santa Ana to Knoxville with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Santa Ana to Knoxville flights to just show those with flexible booking policies.

How can momondo help me find flights from Santa Ana to Knoxville?

momondo helps you find the best flight between Santa Ana and Knoxville by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Santa Ana to Knoxville right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Santa Ana to Knoxville now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Knoxville and let you know when they change.


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