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Cheap flights from Santa Ana to Knoxville from $115

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Santa Ana to Knoxville departing on 4/9. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Santa Ana to Knoxville

Cheap round-trip flights

These are some of the best round-trip flight deals from Santa Ana to Knoxville that have been recently found on momondo from popular airlines, departing in the coming months.

Cheap one-way flights

Flying one-way? These are some of the best deals recently discovered on momondo for flights from Santa Ana to Knoxville.

Cheap last minute flights

Planning a quick getaway from Santa Ana to Knoxville? These are the last-minute flight deals available now.

Cheap direct flights

If you prefer a non-stop journey, check out our latest direct flight deals to Knoxville, so you can enjoy a seamless trip without layovers.

Cheap bus & train deals from Santa Ana to Knoxville

Find recent round-trip train or bus tickets from Santa Ana to Knoxville.

All round-trip flight deals from Santa Ana to Knoxville

The cheapest plane tickets from Santa Ana to Knoxville found on KAYAK recently.
7:45 am - 7:25 pmSNA-TYS
8h 40m1 stop
5:28 am - 9:38 amTYS-SNA
7h 10m1 stop
$229American Airlines
Find Deal
Sat, Feb 15 - Sat, Feb 22
12:36 pm - 11:49 pmSNA-TYS
8h 13m2 stops
5:28 am - 11:48 amTYS-SNA
9h 20m1 stop
$234American Airlines
Find Deal
Sat, Feb 15 - Sat, Feb 22
3:09 pm - 12:12 amSNA-TYS
6h 03m1 stop
2:46 pm - 8:54 pmTYS-SNA
9h 08m1 stop
$259American Airlines
Find Deal
Mon, Feb 10 - Sat, Feb 15
6:45 am - 5:50 pmSNA-TYS
8h 05m2 stops
5:28 am - 11:48 amTYS-SNA
9h 20m1 stop
$264American Airlines
Find Deal
Sat, Feb 15 - Sun, Feb 16
1:13 pm - 11:47 pmSNA-TYS
7h 34m1 stop
5:45 am - 12:03 pmTYS-SNA
9h 18m1 stop
$277Delta
Find Deal
Tue, Feb 11 - Wed, Feb 12
7:00 am - 11:04 pmSNA-TYS
13h 04m2 stops
2:07 pm - 7:43 pmTYS-SNA
8h 36m1 stop
$282Delta
Find Deal
Tue, Feb 4 - Sat, Feb 8
6:45 am - 9:52 pmSNA-TYS
12h 07m1 stop
8:00 am - 9:30 pmTYS-SNA
16h 30m2 stops
Mon, Mar 10 - Tue, Mar 11
12:27 pm - 11:30 pmSNA-TYS
8h 03m1 stop
5:25 pm - 10:29 pmTYS-SNA
8h 04m1 stop
$319United Airlines
Find Deal
Tue, Mar 25 - Tue, Apr 1
3:35 pm - 6:36 pmSNA-TYS
24h 01m3 stops
9:59 pm - 8:52 pmTYS-SNA
25h 53m3 stops
Mon, Mar 10 - Tue, Mar 11
8:00 am - 8:02 pmSNA-TYS
9h 02m1 stop
7:00 am - 5:12 pmTYS-SNA
13h 12m2 stops
$324United Airlines
Find Deal
Tue, Mar 25 - Tue, Apr 1
12:29 pm - 11:56 pmSNA-TYS
8h 27m1 stop
$115American Airlines
Find Deal
Wed, Apr 9
1:00 pm - 11:56 pmSNA-TYS
7h 56m2 stops
$120American Airlines
Find Deal
Wed, Apr 9
12:19 pm - 4:08 pmSNA-TYS
24h 49m1 stop
$156Frontier
Find Deal
Wed, May 21
6:45 am - 8:09 amSNA-TYS
22h 24m3 stops
Mon, Feb 3
11:39 am - 4:08 pmSNA-TYS
25h 29m1 stop
$200Frontier
Find Deal
Sat, May 24
11:55 am - 6:46 pmSNA-TYS
27h 51m3 stops
Wed, Apr 9
11:55 am - 6:46 pmSNA-TYS
27h 51m3 stops
Wed, Apr 9
4:30 pm - 1:57 pmSNA-TYS
18h 27m2 stops
Wed, May 21
8:19 pm - 10:55 pmSNA-TYS
23h 36m2 stops
$362Allegiant Air
Find Deal
Fri, May 23
8:55 am - 11:59 pmSNA-TYS
12h 04m3 stops
$852United Airlines
Find Deal
Sat, May 24
8:55 am - 6:21 pmSNA-TYS
6h 26m1 stop
5:23 am - 9:36 amTYS-SNA
7h 13m1 stop
$1,866American Airlines
Find Deal
Sun, Jan 26 - Thu, Jan 30
7:45 am - 5:27 pmSNA-TYS
6h 42m1 stop
5:23 am - 11:57 amTYS-SNA
9h 34m2 stops
$1,871American Airlines
Find Deal
Sun, Jan 26 - Thu, Jan 30
10:29 am - 11:58 pmSNA-TYS
10h 29m2 stops
5:23 am - 11:57 amTYS-SNA
9h 34m2 stops
$1,927American Airlines
Find Deal
Sun, Jan 26 - Thu, Jan 30
11:43 am - 11:58 pmSNA-TYS
9h 15m2 stops
5:23 am - 11:57 amTYS-SNA
9h 34m2 stops
$2,103American Airlines
Find Deal
Sun, Jan 26 - Thu, Jan 30

American Airlines flights from Santa Ana to Knoxville

Our best American Airlines deals on Santa Ana to Knoxville flight tickets
American Airlines
Feb 15
SNA7:45 amSanta Ana J. Wayne/Orange Cnty
8h 40m
1 stop
TYS7:25 pmKnoxville McGhee Tyson
Feb 22
TYS5:28 amKnoxville McGhee Tyson
7h 10m
1 stop
SNA9:38 amSanta Ana J. Wayne/Orange Cnty
American Airlines
Feb 15
SNA12:36 pmSanta Ana J. Wayne/Orange Cnty
8h 13m
2 stops
TYS11:49 pmKnoxville McGhee Tyson
Feb 22
TYS5:28 amKnoxville McGhee Tyson
9h 20m
1 stop
SNA11:48 amSanta Ana J. Wayne/Orange Cnty
American Airlines
Feb 10
SNA3:09 pmSanta Ana J. Wayne/Orange Cnty
6h 03m
1 stop
TYS12:12 amKnoxville McGhee Tyson
Feb 15
TYS2:46 pmKnoxville McGhee Tyson
9h 08m
1 stop
SNA8:54 pmSanta Ana J. Wayne/Orange Cnty

United Airlines flights from Santa Ana to Knoxville

Our best United Airlines deals on Santa Ana to Knoxville flight tickets
United Airlines
Mar 25
SNA12:27 pmSanta Ana J. Wayne/Orange Cnty
8h 03m
1 stop
TYS11:30 pmKnoxville McGhee Tyson
Apr 1
TYS5:25 pmKnoxville McGhee Tyson
8h 04m
1 stop
SNA10:29 pmSanta Ana J. Wayne/Orange Cnty
United Airlines
Mar 25
SNA8:00 amSanta Ana J. Wayne/Orange Cnty
9h 02m
1 stop
TYS8:02 pmKnoxville McGhee Tyson
Apr 1
TYS7:00 amKnoxville McGhee Tyson
13h 12m
2 stops
SNA5:12 pmSanta Ana J. Wayne/Orange Cnty
United Airlines
Mar 25
SNA6:18 pmSanta Ana J. Wayne/Orange Cnty
12h 41m
2 stops
TYS9:59 amKnoxville McGhee Tyson
Apr 2
TYS7:00 amKnoxville McGhee Tyson
10h 41m
2 stops
SNA2:41 pmSanta Ana J. Wayne/Orange Cnty

See travel insights to Knoxville from

How to get the cheapest flight ticket from Santa Ana to Knoxville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Knoxville?

The month of January is, on average, the cheapest month to fly to Knoxville from Santa Ana, with most prices found around $378. If you aren’t able to travel during the month of January, then book flights to Knoxville from Santa Ana during February instead. Flights to Knoxville in February, while not as cheap as those in January, still average around $382.

What is the cheapest day to depart on your flight to Knoxville?

The cheapest day to depart from Santa Ana to Knoxville is on a Saturday. Travelers who choose to depart for Knoxville on a Saturday will often find tickets for as low as $387. When flying out on a Sunday, the most expensive travel day of the week, you can expect to see flight prices from Santa Ana to Knoxville for around $552.

What is the cheapest time of day to depart on your flight to Knoxville?

In the afternoon is the cheapest time of day to fly from Santa Ana to Knoxville when you can find flight prices for as low as $399. Flying to Knoxville in the afternoon is an ideal time because this is during off-peak travel hours. In contrast, the most expensive time of day to depart to Knoxville is in the evening when prices are around $442.

How far in advance should I book a flight to Knoxville?

You are more likely to see cheaper flights to Knoxville from Santa Ana when booking 10 weeks ahead of your departure date. In general, you can expect to find flights to Knoxville for around $470 when searching 10 weeks out.However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Knoxville from Santa Ana for as low as $349 on momondo.

How have Santa Ana to Knoxville flight prices changed over time?

As of January 2025, prices for Santa Ana to Knoxville flights are approximately 182% more expensive when compared to flights at the same time last year.

When to book flights from Santa Ana to Knoxville

Are you open to changing your travel dates? Check out the ideal times to fly from Santa Ana to Knoxville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Santa Ana to Knoxville (SNA to TYS) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santa Ana to Knoxville

Best Price Found

$115

Fastest flight time

5h 47m

Direct flights

None

Airports in Knoxville

1 airport
The best one-way flight to Knoxville from Santa Ana in the past 72 hours is $115. The best round-trip flight deal from Santa Ana to Knoxville found on momondo in the last 72 hours is $229.
The fastest flight from Santa Ana to Knoxville takes 5h 47m
There are no direct flights from Santa Ana to Knoxville. Popular non-direct route for this connection is Santa Ana J. Wayne/Orange Cnty Airport - Knoxville McGhee Tyson Airport.
There is 1 airport near Knoxville: Knoxville McGhee Tyson (TYS)

  • How far is Santa Ana J. Wayne/Orange Cnty to Knoxville McGhee Tyson by plane?

    Santa Ana J. Wayne/Orange Cnty and Knoxville McGhee Tyson are 1919.8 mi apart from one another. 5h 47m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Santa Ana J. Wayne/Orange Cnty Airport to Knoxville McGhee Tyson Airport?

    Prices for flights from Santa Ana J. Wayne/Orange Cnty Airport to Knoxville McGhee Tyson Airport are updated daily.

  • How many operators does momondo search for flights from Santa Ana J. Wayne/Orange Cnty Airport to Knoxville McGhee Tyson Airport?

  • How old do you have to be to fly from Santa Ana J. Wayne/Orange Cnty Airport to Knoxville McGhee Tyson Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Santa Ana J. Wayne/Orange Cnty Airport to Knoxville McGhee Tyson Airport.

  • What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?

    The necessary travel and health documents for your Knoxville McGhee Tyson Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Santa Ana to Knoxville?


Best airlines flying from Santa Ana to Knoxville

Compare and see reviews for airlines that fly from Santa Ana to Knoxville with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $228Free CancellationRating
7.4
8,984 reviews
Search United Airlines flights
DeltaPriceFrom $281Free CancellationRating
8.0
8,521 reviews
Search Delta flights
American AirlinesPriceFrom $287Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Pigeon Forge
Gatlinburg
Cherokee
Bryson City
Morristown
Corbin
Maryville
Crossville
Murphy
Newport
Alcoa
Oak Ridge
Kodak
Clinton
Lenoir City
Dandridge
Jefferson City
Rockford

Why use momondo?

Why should I use momondo to find a flight deal from Santa Ana to Knoxville?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Santa Ana to Knoxville for you.

Can I find flights from Santa Ana to Knoxville with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Santa Ana to Knoxville flights to just show those with flexible booking policies.

How can momondo help me find flights from Santa Ana to Knoxville?

momondo helps you find the best flight between Santa Ana and Knoxville by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Santa Ana to Knoxville right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Santa Ana to Knoxville now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Knoxville and let you know when they change.


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