Cheap flights from Santa Ana to Knoxville from $115
This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Santa Ana to Knoxville departing on 5/13. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
Discover deals from 900+ travel sites with momondo.
Save money when you book flights with momondo
Big names and deals
Big names and deals
Search 100s of travel sites to compare prices.Filter for what you want
Filter for what you want
Free Wi-Fi? Stopover? Instantly customize your results.Trusted and free
Trusted and free
We’re completely free to use - no hidden charges or fees.Price Alerts
Price Alerts
Not ready to book? to track prices.Find the cheapest flights from Santa Ana to Knoxville
Cheap round-trip flights
Cheap one-way flights
Cheap last minute flights
Delta flights from Santa Ana to Knoxville
Our best Delta deals on Santa Ana to Knoxville flight tickets
Alaska Airlines flights from Santa Ana to Knoxville
Our best Alaska Airlines deals on Santa Ana to Knoxville flight tickets
See travel insights to Knoxville from
How to get the cheapest flight ticket from Santa Ana to Knoxville
Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip
What is the cheapest month to fly to Knoxville?
The month of January is, on average, the cheapest month to fly to Knoxville from Santa Ana, with most prices found around $378. If you aren’t able to travel during the month of January, then book flights to Knoxville from Santa Ana during August instead. Flights to Knoxville in August, while not as cheap as those in January, still average around $388.
What is the cheapest day to depart on your flight to Knoxville?
The cheapest day to depart from Santa Ana to Knoxville is on a Saturday. Travelers who choose to depart for Knoxville on a Saturday will often find tickets for as low as $387. When flying out on a Sunday, the most expensive travel day of the week, you can expect to see flight prices from Santa Ana to Knoxville for around $552.
What is the cheapest time of day to depart on your flight to Knoxville?
In the afternoon is the cheapest time of day to fly from Santa Ana to Knoxville when you can find flight prices for as low as $399. Flying to Knoxville in the afternoon is an ideal time because this is during off-peak travel hours. In contrast, the most expensive time of day to depart to Knoxville is in the evening when prices are around $442.
How far in advance should I book a flight to Knoxville?
You are more likely to see cheaper flights to Knoxville from Santa Ana when booking 10 weeks ahead of your departure date. In general, you can expect to find flights to Knoxville for around $470 when searching 10 weeks out.However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Knoxville from Santa Ana for as low as $348 on momondo.
What is the cheapest airline that flies from Santa Ana J. Wayne/Orange Cnty to Knoxville McGhee Tyson?
American Airlines, Delta, and Frontier are the most popular carriers operating from Santa Ana J. Wayne/Orange Cnty to Knoxville McGhee Tyson
What airlines fly to Knoxville?
American Airlines, Delta and United Airlines are the top three most popular airlines that fly to Knoxville from Santa Ana according to our data. American Airlines is the first choice among our users, with 66% of people opting to fly with this airline when traveling to Knoxville. Keep in mind that there are 4 different airlines that fly to Knoxville on a routine basis, so you have a few additional options to choose from.
When to book flights from Santa Ana to Knoxville
Cheap Santa Ana to Knoxville (SNA to TYS) flight deals and tips
Find info about flight duration, direct flights, and airports for your flight from Santa Ana to Knoxville
How far is Santa Ana J. Wayne/Orange Cnty to Knoxville McGhee Tyson by plane?
Santa Ana J. Wayne/Orange Cnty and Knoxville McGhee Tyson are 1919.8 mi apart from one another. 5h 54m is a normal flight duration for this route.
When did momondo last update prices for flights from Santa Ana J. Wayne/Orange Cnty Airport to Knoxville McGhee Tyson Airport?
Prices for flights from Santa Ana J. Wayne/Orange Cnty Airport to Knoxville McGhee Tyson Airport are updated daily.
How many operators does momondo search for flights from Santa Ana J. Wayne/Orange Cnty Airport to Knoxville McGhee Tyson Airport?
As of April 2025, there are 3 operators available to choose from for flights from Santa Ana J. Wayne/Orange Cnty Airport to Knoxville McGhee Tyson Airport.
How old do you have to be to fly from Santa Ana J. Wayne/Orange Cnty Airport to Knoxville McGhee Tyson Airport?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Santa Ana J. Wayne/Orange Cnty Airport to Knoxville McGhee Tyson Airport.
What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?
The necessary travel and health documents for your Knoxville McGhee Tyson Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.
What is the most popular airline from Santa Ana to Knoxville?
momondo data reveals that the most frequently booked airline on the route from Santa Ana to Knoxville is American Airlines, representing 80% of all bookings. The subsequent popular airlines are United Airlines at 11% and Delta at 9%.
Best airlines flying from Santa Ana to Knoxville
Compare and see reviews for airlines that fly from Santa Ana to Knoxville with momondo
| Airline | Rating | Free Cancellation | Price | ||
|---|---|---|---|---|---|
| PriceFrom $239 | Free Cancellation | Rating 7.4 8,616 reviews | |||
| PriceFrom $276 | Free Cancellation | Rating 7.2 10,000 reviews | |||
| PriceFrom $287 | Free Cancellation | Rating 8.0 7,897 reviews |
Traveling to a place near Knoxville?
Book flights to Knoxville if you plan to visit one of these locationsWhy use momondo?
Why should I use momondo to find a flight deal from Santa Ana to Knoxville?
We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Santa Ana to Knoxville for you.
Can I find flights from Santa Ana to Knoxville with flexible booking policies on momondo?
Yes. momondo allows you to filter the results for Santa Ana to Knoxville flights to just show those with flexible booking policies.
How can momondo help me find flights from Santa Ana to Knoxville?
momondo helps you find the best flight between Santa Ana and Knoxville by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.
I’m not ready to book a flight from Santa Ana to Knoxville right now. Can momondo alert me if prices change?
If you are not ready to book a flight from Santa Ana to Knoxville now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Knoxville and let you know when they change.