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Cheap flights from San Francisco to Knoxville from $216

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from San Francisco to Knoxville departing on 5/10. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from San Francisco to Knoxville

Cheap round-trip flights

KAYAK's recommended round-trip deals from the most popular airlines that fly from San Francisco to Knoxville.
Delta Logo
10:59 pm - 11:23 amSFO-TYS
9h 24m1 stop
Delta Logo
4:22 pm - 9:23 pmTYS-SFO
8h 01m1 stop
$297Delta
Find Deal
Wed, May 28 - Fri, May 30
Delta Logo
10:30 pm - 10:23 amSFO-TYS
8h 53m1 stop
Delta Logo
6:50 am - 1:29 pmTYS-SFO
9h 39m1 stop
$303Delta
Find Deal
Sat, May 31 - Wed, Jun 4
American Airlines Logo
11:30 pm - 11:41 amSFO-TYS
9h 11m1 stop
American Airlines Logo
2:50 pm - 9:27 pmTYS-SFO
9h 37m1 stop
$309American Airlines
Find Deal
Tue, Jun 3 - Sat, Jun 7
Frontier Logo
6:37 am - 4:29 pmSFO-TYS
6h 52m1 stop
Frontier Logo
5:25 pm - 12:24 amTYS-SFO
9h 59m1 stop
$321Frontier
Find Deal
Sun, Jun 1 - Thu, Jun 12
United Airlines Logo
12:10 am - 10:16 amSFO-TYS
7h 06m1 stop
United Airlines Logo
7:00 am - 1:33 pmTYS-SFO
9h 33m1 stop
$325United Airlines
Find Deal
Tue, May 13 - Wed, May 21
Frontier Logo
6:35 am - 4:35 pmSFO-TYS
7h 00m1 stop
Frontier Logo
5:25 pm - 12:09 amTYS-SFO
9h 44m1 stop
$330Frontier
Find Deal
Thu, May 29 - Sun, Jun 1
American Airlines Logo
8:16 am - 8:00 pmSFO-TYS
8h 44m1 stop
American Airlines Logo
2:56 pm - 8:19 pmTYS-SFO
8h 23m1 stop
$334American Airlines
Find Deal
Sat, May 24 - Tue, May 27
United Airlines Logo
11:59 pm - 10:09 amSFO-TYS
7h 10m1 stop
United Airlines Logo
4:52 pm - 9:20 pmTYS-SFO
7h 28m1 stop
$359United Airlines
Find Deal
Thu, May 29 - Fri, May 30
 Logo
6:09 pm - 11:42 amSFO-TYS
14h 33m1 stop
 Logo
3:46 pm - 8:08 amTYS-SFO
19h 22m2 stops
Sun, Jun 1 - Thu, Jun 12
 Logo
6:09 pm - 11:42 amSFO-TYS
14h 33m1 stop
 Logo
9:09 am - 10:53 pmTYS-SFO
40h 44m3 stops
Sun, Jun 1 - Thu, Jun 12

United Airlines flights from San Francisco to Knoxville

Our best United Airlines deals on San Francisco to Knoxville flight tickets
United Airlines
May 13
SFO12:10 amSan Francisco
7h 06m
1 stop
TYS10:16 amKnoxville McGhee Tyson
May 21
TYS7:00 amKnoxville McGhee Tyson
9h 33m
1 stop
SFO1:33 pmSan Francisco
United Airlines
May 29
SFO11:59 pmSan Francisco
7h 10m
1 stop
TYS10:09 amKnoxville McGhee Tyson
May 30
TYS4:52 pmKnoxville McGhee Tyson
7h 28m
1 stop
SFO9:20 pmSan Francisco
United Airlines
Sep 5
SFO5:15 amSan Francisco
6h 24m
1 stop
TYS2:39 pmKnoxville McGhee Tyson
Sep 9
TYS12:00 pmKnoxville McGhee Tyson
8h 50m
1 stop
SFO5:50 pmSan Francisco

Delta flights from San Francisco to Knoxville

Our best Delta deals on San Francisco to Knoxville flight tickets
Delta
May 28
SFO10:59 pmSan Francisco
9h 24m
1 stop
TYS11:23 amKnoxville McGhee Tyson
May 30
TYS4:22 pmKnoxville McGhee Tyson
8h 01m
1 stop
SFO9:23 pmSan Francisco
Delta
May 31
SFO10:30 pmSan Francisco
8h 53m
1 stop
TYS10:23 amKnoxville McGhee Tyson
Jun 4
TYS6:50 amKnoxville McGhee Tyson
9h 39m
1 stop
SFO1:29 pmSan Francisco
Delta
May 30
SFO6:15 amSan Francisco
8h 28m
1 stop
TYS5:43 pmKnoxville McGhee Tyson
May 31
TYS5:45 amKnoxville McGhee Tyson
9h 00m
1 stop
SFO11:45 amSan Francisco

See travel insights to Knoxville from

How to get the cheapest flight ticket from San Francisco to Knoxville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Knoxville?

The month of August is, on average, the cheapest month to fly to Knoxville from San Francisco, with most prices found around $400. If you aren’t able to travel during the month of August, then book flights to Knoxville from San Francisco during February instead. Flights to Knoxville in February, while not as cheap as those in August, still average around $415.

What is the cheapest day to depart on your flight to Knoxville?

The cheapest day to depart from San Francisco to Knoxville is on a Tuesday. Travelers who choose to depart for Knoxville on a Tuesday will often find tickets for as low as $425. When flying out on a Friday, the most expensive travel day of the week, you can expect to see flight prices from San Francisco to Knoxville for around $555.

What is the cheapest time of day to depart on your flight to Knoxville?

In the evening is the cheapest time of day to fly from San Francisco to Knoxville when you can find flight prices for as low as $453. Flying to Knoxville in the evening is an ideal time because this is during off-peak travel hours. In contrast, the most expensive time of day to depart to Knoxville is at noon when prices are around $514.

How far in advance should I book a flight to Knoxville?

You are more likely to see cheaper flights to Knoxville from San Francisco when booking 16 weeks ahead of your departure date. In general, you can expect to find flights to Knoxville for around $490 when searching 16 weeks out.However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Knoxville from San Francisco for as low as $382 on momondo.

How have San Francisco to Knoxville flight prices changed over time?

As of April 2025, prices for San Francisco to Knoxville flights are approximately 26% more expensive when compared to flights at the same time last year.

When to book flights from San Francisco to Knoxville

Are you open to changing your travel dates? Check out the ideal times to fly from San Francisco to Knoxville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap San Francisco to Knoxville (SFO to TYS) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from San Francisco to Knoxville

Best Price Found

$216

Fastest flight time

6h 15m

Direct flights

None

Airports in Knoxville

1 airport
The best one-way flight to Knoxville from San Francisco in the past 72 hours is $216. The best round-trip flight deal from San Francisco to Knoxville found on momondo in the last 72 hours is $297.
The fastest flight from San Francisco to Knoxville takes 6h 15m
There are no direct flights from San Francisco to Knoxville. Popular non-direct route for this connection is San Francisco Airport - Knoxville McGhee Tyson Airport.
There is 1 airport near Knoxville: Knoxville McGhee Tyson (TYS)

  • How far is San Francisco to Knoxville McGhee Tyson by plane?

    The straight-line distance from San Francisco to Knoxville McGhee Tyson is 2114.7 mi. In terms of flight time, this usually takes a little over 6h 15m.

  • When did momondo last update prices for flights from San Francisco Airport to Knoxville McGhee Tyson Airport?

    Prices for flights from San Francisco Airport to Knoxville McGhee Tyson Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from San Francisco Airport to Knoxville McGhee Tyson Airport?

  • How old do you have to be to fly from San Francisco Airport to Knoxville McGhee Tyson Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from San Francisco Airport to Knoxville McGhee Tyson Airport.

  • What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?

    The travel and health documents you'll need for your trip to Knoxville McGhee Tyson Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Knoxville McGhee Tyson Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from San Francisco to Knoxville?


Best airlines flying from San Francisco to Knoxville

Compare and see reviews for airlines that fly from San Francisco to Knoxville with momondo
Airline
Rating
Free Cancellation
Price
FrontierPriceFrom $149Free CancellationRating
6.0
3,281 reviews
Search Frontier flights
DeltaPriceFrom $298Free CancellationRating
8.0
7,916 reviews
Search Delta flights
American AirlinesPriceFrom $308Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights
United AirlinesPriceFrom $326Free CancellationRating
7.4
8,667 reviews
Search United Airlines flights

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Pigeon Forge
Gatlinburg
Cherokee
Bryson City
Morristown
Corbin
Crossville
Murphy
Maryville
Newport
Alcoa
Oak Ridge
Kodak
Lenoir City
Dandridge
Clinton
Jefferson City
Rockford

Why use momondo?

Why should I use momondo to find a flight deal from San Francisco to Knoxville?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from San Francisco to Knoxville for you.

Can I find flights from San Francisco to Knoxville with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for San Francisco to Knoxville flights to just show those with flexible booking policies.

How can momondo help me find flights from San Francisco to Knoxville?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from San Francisco to Knoxville.

I’m not ready to book a flight from San Francisco to Knoxville right now. Can momondo alert me if prices change?

Yes. momondo can track prices for San Francisco to Knoxville flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.


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