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Cheap flights from San Francisco to Knoxville from $120

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from San Francisco to Knoxville departing on 5/28. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from San Francisco to Knoxville

Cheap round-trip flights

KAYAK's recommended round-trip deals from the most popular airlines that fly from San Francisco to Knoxville.
American Airlines Logo
12:21 am - 12:29 pmSFO-TYS
9h 08m1 stop
American Airlines Logo
5:15 am - 11:08 amTYS-SFO
8h 53m1 stop
$279American Airlines
Find Deal
Fri, Apr 18 - Sat, Apr 26
Frontier Logo
6:35 am - 4:35 pmSFO-TYS
7h 00m1 stop
Frontier Logo
5:30 pm - 12:09 amTYS-SFO
9h 39m1 stop
$298Frontier
Find Deal
Thu, May 22 - Sun, May 25
Delta Logo
10:45 pm - 10:03 amSFO-TYS
8h 18m1 stop
Delta Logo
7:30 am - 2:23 pmTYS-SFO
9h 53m1 stop
$329Delta
Find Deal
Thu, Jul 10 - Tue, Jul 15
United Airlines Logo
7:35 am - 8:06 pmSFO-TYS
9h 31m1 stop
United Airlines Logo
7:00 am - 11:28 amTYS-SFO
7h 28m1 stop
$331United Airlines
Find Deal
Wed, Apr 16 - Sun, Apr 20
Delta Logo
9:00 am - 6:13 pmSFO-TYS
6h 13m1 stop
Delta Logo
5:15 pm - 10:44 pmTYS-SFO
8h 29m1 stop
$354Delta
Find Deal
Thu, Sep 18 - Tue, Sep 23
United Airlines Logo
12:10 am - 10:15 amSFO-TYS
7h 05m1 stop
United Airlines Logo
7:25 pm - 12:58 amTYS-SFO
8h 33m1 stop
$384United Airlines
Find Deal
Tue, May 20 - Sun, May 25
 Logo
1:15 pm - 10:54 pmSFO-TYS
30h 39m2 stops
 Logo
8:35 pm - 5:13 pmTYS-SFO
23h 38m3 stops
Wed, May 28 - Sun, Jun 1
Alaska Airlines Logo
11:48 am - 11:30 pmSFO-TYS
8h 42m1 stop
Alaska Airlines Logo
5:15 am - 9:57 pmTYS-SFO
19h 42m1 stop
$474Alaska Airlines
Find Deal
Tue, Apr 22 - Sun, Apr 27
 Logo
6:09 pm - 5:39 pmSFO-TYS
20h 30m2 stops
 Logo
10:00 am - 9:49 amTYS-SFO
26h 49m2 stops
Thu, May 15 - Sun, May 18
Alaska Airlines Logo
11:48 am - 11:30 pmSFO-TYS
8h 42m1 stop
Alaska Airlines Logo
5:15 am - 9:57 pmTYS-SFO
19h 42m1 stop
$689Alaska Airlines
Find Deal
Thu, Apr 24 - Sun, Apr 27

Delta flights from San Francisco to Knoxville

Our best Delta deals on San Francisco to Knoxville flight tickets
Delta
Jul 10
SFO10:45 pmSan Francisco
8h 18m
1 stop
TYS10:03 amKnoxville McGhee Tyson
Jul 15
TYS7:30 amKnoxville McGhee Tyson
9h 53m
1 stop
SFO2:23 pmSan Francisco
Delta
Sep 18
SFO9:00 amSan Francisco
6h 13m
1 stop
TYS6:13 pmKnoxville McGhee Tyson
Sep 23
TYS5:15 pmKnoxville McGhee Tyson
8h 29m
1 stop
SFO10:44 pmSan Francisco
Delta
Apr 12
SFO5:55 amSan Francisco
8h 49m
1 stop
TYS5:44 pmKnoxville McGhee Tyson
Apr 19
TYS8:59 amKnoxville McGhee Tyson
7h 19m
1 stop
SFO1:18 pmSan Francisco

United Airlines flights from San Francisco to Knoxville

Our best United Airlines deals on San Francisco to Knoxville flight tickets
United Airlines
Apr 16
SFO7:35 amSan Francisco
9h 31m
1 stop
TYS8:06 pmKnoxville McGhee Tyson
Apr 20
TYS7:00 amKnoxville McGhee Tyson
7h 28m
1 stop
SFO11:28 amSan Francisco
United Airlines
May 20
SFO12:10 amSan Francisco
7h 05m
1 stop
TYS10:15 amKnoxville McGhee Tyson
May 25
TYS7:25 pmKnoxville McGhee Tyson
8h 33m
1 stop
SFO12:58 amSan Francisco
United Airlines
May 28
SFO5:05 amSan Francisco
6h 44m
1 stop
TYS2:49 pmKnoxville McGhee Tyson
Jun 1
TYS4:52 pmKnoxville McGhee Tyson
9h 38m
1 stop
SFO11:30 pmSan Francisco

See travel insights to Knoxville from

How to get the cheapest flight ticket from San Francisco to Knoxville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between San Francisco and Knoxville?

What is the cheapest month to fly to Knoxville?

The month of August is, on average, the cheapest month to fly to Knoxville from San Francisco, with most prices found around $399. If you aren’t able to travel during the month of August, then book flights to Knoxville from San Francisco during February instead. Flights to Knoxville in February, while not as cheap as those in August, still average around $415.

What is the cheapest day to depart on your flight to Knoxville?

The cheapest day to depart from San Francisco to Knoxville is on a Tuesday. Travelers who choose to depart for Knoxville on a Tuesday will often find tickets for as low as $425. When flying out on a Friday, the most expensive travel day of the week, you can expect to see flight prices from San Francisco to Knoxville for around $555.

What is the cheapest time of day to depart on your flight to Knoxville?

In the evening is the cheapest time of day to fly from San Francisco to Knoxville when you can find flight prices for as low as $453. Flying to Knoxville in the evening is an ideal time because this is during off-peak travel hours. In contrast, the most expensive time of day to depart to Knoxville is at noon when prices are around $514.

How far in advance should I book a flight to Knoxville?

You are more likely to see cheaper flights to Knoxville from San Francisco when booking 21 weeks ahead of your departure date. In general, you can expect to find flights to Knoxville for around $486 when searching 21 weeks out.However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Knoxville from San Francisco for as low as $409 on momondo.

How have San Francisco to Knoxville flight prices changed over time?

As of April 2025, prices for San Francisco to Knoxville flights are approximately 27% more expensive when compared to flights at the same time last year.

When to book flights from San Francisco to Knoxville

Are you open to changing your travel dates? Check out the ideal times to fly from San Francisco to Knoxville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap San Francisco to Knoxville (SFO to TYS) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from San Francisco to Knoxville

Best Price Found

$120

Fastest flight time

6h 13m

Direct flights

None

Airports in Knoxville

1 airport
The best one-way flight to Knoxville from San Francisco in the past 72 hours is $120. The best round-trip flight deal from San Francisco to Knoxville found on momondo in the last 72 hours is $279.
The fastest flight from San Francisco to Knoxville takes 6h 13m
There are no direct flights from San Francisco to Knoxville. Popular non-direct route for this connection is San Francisco Airport - Knoxville McGhee Tyson Airport.
There is 1 airport near Knoxville: Knoxville McGhee Tyson (TYS)

  • How far is San Francisco to Knoxville McGhee Tyson by plane?

    The straight-line distance from San Francisco to Knoxville McGhee Tyson is 2114.7 mi. In terms of flight time, this usually takes a little over 6h 13m.

  • When did momondo last update prices for flights from San Francisco Airport to Knoxville McGhee Tyson Airport?

    Prices for flights from San Francisco Airport to Knoxville McGhee Tyson Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from San Francisco Airport to Knoxville McGhee Tyson Airport?

  • How old do you have to be to fly from San Francisco Airport to Knoxville McGhee Tyson Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from San Francisco Airport to Knoxville McGhee Tyson Airport.

  • What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?

    The travel and health documents you'll need for your trip to Knoxville McGhee Tyson Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Knoxville McGhee Tyson Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from San Francisco to Knoxville?


Best airlines flying from San Francisco to Knoxville

Compare and see reviews for airlines that fly from San Francisco to Knoxville with momondo
Airline
Rating
Free Cancellation
Price
FrontierPriceFrom $149Free CancellationRating
5.9
3,277 reviews
Search Frontier flights
DeltaPriceFrom $282Free CancellationRating
8.0
7,899 reviews
Search Delta flights
American AirlinesPriceFrom $308Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights
United AirlinesPriceFrom $319Free CancellationRating
7.4
8,615 reviews
Search United Airlines flights

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Pigeon Forge
Gatlinburg
Cherokee
Bryson City
Morristown
Corbin
Murphy
Crossville
Maryville
Newport
Alcoa
Oak Ridge
Kodak
Lenoir City
Dandridge
Clinton
Jefferson City
Rockford

Why use momondo?

Why should I use momondo to find a flight deal from San Francisco to Knoxville?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from San Francisco to Knoxville for you.

Can I find flights from San Francisco to Knoxville with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for San Francisco to Knoxville flights to just show those with flexible booking policies.

How can momondo help me find flights from San Francisco to Knoxville?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from San Francisco to Knoxville.

I’m not ready to book a flight from San Francisco to Knoxville right now. Can momondo alert me if prices change?

Yes. momondo can track prices for San Francisco to Knoxville flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.


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