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Cheap flights from San Francisco to Greenville from $179

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from San Francisco to Greenville departing on 4/29. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from San Francisco to Greenville

Cheap round-trip flights

KAYAK's recommended round-trip deals from the most popular airlines that fly from San Francisco to Greenville.
12:21 am - 9:53 amSFO-GSP
6h 32m1 stop
4:19 pm - 9:05 pmGSP-SFO
7h 46m1 stop
$335American Airlines
Find Deal
Mon, Apr 21 - Sat, Apr 26
12:21 am - 9:53 amSFO-GSP
6h 32m1 stop
6:36 pm - 11:01 pmGSP-SFO
7h 25m1 stop
$351American Airlines
Find Deal
Mon, Apr 28 - Tue, May 6
9:05 pm - 9:55 amSFO-GSP
9h 50m1 stop
10:45 am - 4:25 pmGSP-SFO
8h 40m2 stops
$356Southwest
Find Deal
Thu, Sep 11 - Mon, Sep 15
7:00 am - 5:01 pmSFO-GSP
7h 01m1 stop
5:53 pm - 12:08 amGSP-SFO
9h 15m1 stop
$357American Airlines
Find Deal
Sat, Jun 28 - Sat, Jul 5
5:15 pm - 9:55 amSFO-GSP
13h 40m2 stops
10:45 am - 4:25 pmGSP-SFO
8h 40m2 stops
$361Southwest
Find Deal
Thu, Sep 11 - Mon, Sep 15
11:20 pm - 10:09 amSFO-GSP
7h 49m1 stop
5:18 pm - 11:59 pmGSP-SFO
9h 41m1 stop
$389United Airlines
Find Deal
Mon, May 19 - Fri, May 23
12:10 am - 10:09 amSFO-GSP
6h 59m1 stop
5:18 pm - 11:59 pmGSP-SFO
9h 41m1 stop
$413United Airlines
Find Deal
Sun, May 18 - Fri, May 23
5:50 am - 5:44 pmSFO-GSP
8h 54m1 stop
5:30 am - 11:45 amGSP-SFO
9h 15m1 stop
$430Delta
Find Deal
Wed, May 7 - Sun, May 11
11:51 am - 11:53 pmSFO-GSP
9h 02m1 stop
7:10 am - 5:29 pmGSP-SFO
13h 19m2 stops
$464Delta
Find Deal
Tue, Apr 22 - Sat, Apr 26
6:09 pm - 8:28 pmSFO-GSP
23h 19m2 stops
3:50 pm - 5:13 pmGSP-SFO
28h 23m3 stops
Wed, May 21 - Fri, May 23

American Airlines flights from San Francisco to Greenville

Our best American Airlines deals on San Francisco to Greenville flight tickets
American Airlines
Apr 21
SFO12:21 amSan Francisco
6h 32m
1 stop
GSP9:53 amGreenville
Apr 26
GSP4:19 pmGreenville
7h 46m
1 stop
SFO9:05 pmSan Francisco
American Airlines
Apr 28
SFO12:21 amSan Francisco
6h 32m
1 stop
GSP9:53 amGreenville
May 6
GSP6:36 pmGreenville
7h 25m
1 stop
SFO11:01 pmSan Francisco
American Airlines
Jun 28
SFO7:00 amSan Francisco
7h 01m
1 stop
GSP5:01 pmGreenville
Jul 5
GSP5:53 pmGreenville
9h 15m
1 stop
SFO12:08 amSan Francisco

Southwest flights from San Francisco to Greenville

Our best Southwest deals on San Francisco to Greenville flight tickets
Southwest
Sep 11
SFO9:05 pmSan Francisco
9h 50m
1 stop
GSP9:55 amGreenville
Sep 15
GSP10:45 amGreenville
8h 40m
2 stops
SFO4:25 pmSan Francisco
Southwest
Sep 11
SFO5:15 pmSan Francisco
13h 40m
2 stops
GSP9:55 amGreenville
Sep 15
GSP10:45 amGreenville
8h 40m
2 stops
SFO4:25 pmSan Francisco
Southwest
May 5
SFO5:25 amSan Francisco
10h 10m
2 stops
GSP6:35 pmGreenville
May 8
GSP11:20 amGreenville
13h 50m
2 stops
SFO10:10 pmSan Francisco

See travel insights to Greenville from

How to get the cheapest flight ticket from San Francisco to Greenville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Greenville?

The month of August is another great option to travel to Greenville, with average flight prices from San Francisco averaging around $422.

What is the cheapest day to depart on your flight to Greenville?

According to our data, Saturday is the cheapest day to fly to Greenville from San Francisco. The lowest ticket price found for a Saturday departure recently was $393. Keep in mind that prices can always vary depending on your route and whether or not you are flying domestic or international. If your travel schedule is flexible, try to avoid departing on a Monday because tickets tend to average around $714. These prices are subject to change though, so be sure to set up a Price Alert for flights to Greenville.

What is the cheapest time of day to depart on your flight to Greenville?

Our most recent data shows that the best time of day to fly to Greenville is in the morning. Flights from San Francisco to Greenville during this time can be as low as $512. Flights to Greenville are more costly at noon, with an average ticket price of $545. Departure times at noon fall within the peak daily travel times, which is why tickets can be more expensive.

How far in advance should I book a flight to Greenville?

You are more likely to see cheaper flights to Greenville from San Francisco when booking 11 weeks ahead of your departure date. In general, you can expect to find flights to Greenville for around $487 when searching 11 weeks out.However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Greenville from San Francisco for as low as $343 on momondo.

How have San Francisco to Greenville flight prices changed over time?

As of March 2025, prices for San Francisco to Greenville flights are approximately 11% more expensive when compared to flights at the same time last year.

When to book flights from San Francisco to Greenville

Are you open to changing your travel dates? Check out the ideal times to fly from San Francisco to Greenville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap San Francisco to Greenville (SFO to GSP) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from San Francisco to Greenville

Best Price Found

$179

Fastest flight time

6h 17m

Direct flights

None

Airports in Greenville

1 airport
The best one-way flight to Greenville from San Francisco in the past 72 hours is $179. The best round-trip flight deal from San Francisco to Greenville found on momondo in the last 72 hours is $335.
The fastest flight from San Francisco to Greenville takes 6h 17m
There are no direct flights from San Francisco to Greenville. Popular non-direct route for this connection is San Francisco Airport - Greenville Airport.
There is 1 airport near Greenville: Greenville (GSP)

  • How far is San Francisco to Greenville by plane?

    The straight-line distance from San Francisco to Greenville is 2218.5 mi. Flights usually cover this in 6h 17m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from San Francisco Airport to Greenville Airport?

    Prices for flights from San Francisco Airport to Greenville Airport refresh daily.

  • How many operators does momondo search for flights from San Francisco Airport to Greenville Airport?

  • How old do you have to be to fly from San Francisco Airport to Greenville Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from San Francisco Airport to Greenville Airport.

  • What documentation or ID do you need to fly to Greenville Airport?

    The required travel and health documents for your Greenville Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Greenville Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from San Francisco to Greenville?


Best airlines flying from San Francisco to Greenville

Compare and see reviews for airlines that fly from San Francisco to Greenville with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $278Free CancellationRating
8.0
7,899 reviews
Search Delta flights
American AirlinesPriceFrom $322Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights
United AirlinesPriceFrom $412Free CancellationRating
7.4
8,614 reviews
Search United Airlines flights

Traveling to a place near Greenville?

Book flights to Greenville if you plan to visit one of these locations
Anderson
Simpsonville
Greenwood
Seneca
Greer
Duncan

Why use momondo?

Why should I use momondo to find a flight deal from San Francisco to Greenville?

It is quick and easy to find San Francisco to Greenville flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Greenville that suits you.

Can I find flights from San Francisco to Greenville with flexible booking policies on momondo?

All flight searches from San Francisco to Greenville on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from San Francisco to Greenville?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Greenville from San Francisco.

I’m not ready to book a flight from San Francisco to Greenville right now. Can momondo alert me if prices change?

If you are not ready to book a flight from San Francisco to Greenville now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Greenville and let you know when they change.


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