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Cheap flights from Portland, Maine to Greenville from $136

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Portland, Maine to Greenville departing on 7/3. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Portland, Maine to Greenville

Cheap round-trip flights

KAYAK's recommended round-trip deals from the most popular airlines that fly from Portland, Maine to Greenville.
American Airlines Logo
4:02 pm - 8:26 pmPWM-GSP
4h 24m1 stop
American Airlines Logo
6:36 pm - 11:03 pmGSP-PWM
4h 27m1 stop
$284American Airlines
Find Deal
Wed, Jun 11 - Sat, Jun 14
Delta Logo
6:00 am - 10:57 amPWM-GSP
4h 57m1 stop
Delta Logo
5:30 am - 2:44 pmGSP-PWM
9h 14m2 stops
$289Delta
Find Deal
Wed, Jun 11 - Sat, Jun 14
Delta Logo
6:03 am - 2:14 pmPWM-GSP
8h 11m2 stops
Delta Logo
11:15 am - 9:24 pmGSP-PWM
10h 09m2 stops
$294Delta
Find Deal
Wed, Jun 11 - Sat, Jun 14
Delta Logo
5:35 pm - 11:55 pmPWM-GSP
6h 20m1 stop
Delta Logo
7:59 pm - 12:26 amGSP-PWM
4h 27m1 stop
$332Delta
Find Deal
Tue, Jun 24 - Fri, Jun 27
Delta Logo
6:03 am - 1:14 pmPWM-GSP
7h 11m2 stops
Delta Logo
6:58 pm - 11:30 pmGSP-PWM
4h 32m1 stop
$337Delta
Find Deal
Tue, Jun 24 - Fri, Jun 27
American Airlines Logo
6:00 am - 10:27 amPWM-GSP
4h 27m1 stop
American Airlines Logo
10:53 am - 5:11 pmGSP-PWM
6h 18m1 stop
$367American Airlines
Find Deal
Sun, Jun 1 - Sun, Jun 15
American Airlines Logo
11:07 am - 9:03 pmPWM-GSP
9h 56m1 stop
American Airlines Logo
6:54 am - 3:36 pmGSP-PWM
8h 42m1 stop
$395American Airlines
Find Deal
Fri, May 9 - Tue, May 13
Delta Logo
6:05 am - 11:08 amPWM-GSP
5h 03m1 stop
Delta Logo
5:30 am - 12:57 pmGSP-PWM
7h 27m2 stops
$402Delta
Find Deal
Fri, May 9 - Tue, May 13
Delta Logo
1:40 pm - 11:52 pmPWM-GSP
10h 12m2 stops
Delta Logo
6:30 am - 12:57 pmGSP-PWM
6h 27m2 stops
$407Delta
Find Deal
Fri, May 9 - Tue, May 13
Breeze Airways Logo
3:17 pm - 7:26 pmPWM-GSP
4h 09m1 stop
Breeze Airways Logo
8:06 pm - 2:07 pmGSP-PWM
18h 01m3 stops
$619Breeze Airways
Find Deal
Sun, Jun 1 - Sun, Jun 15

American Airlines flights from Portland, Maine to Greenville

Our best American Airlines deals on Portland, Maine to Greenville flight tickets
American Airlines
Jun 11
PWM4:02 pmPortland
4h 24m
1 stop
GSP8:26 pmGreenville
Jun 14
GSP6:36 pmGreenville
4h 27m
1 stop
PWM11:03 pmPortland
American Airlines
Jun 1
PWM6:00 amPortland
4h 27m
1 stop
GSP10:27 amGreenville
Jun 15
GSP10:53 amGreenville
6h 18m
1 stop
PWM5:11 pmPortland
American Airlines
May 9
PWM11:07 amPortland
9h 56m
1 stop
GSP9:03 pmGreenville
May 13
GSP6:54 amGreenville
8h 42m
1 stop
PWM3:36 pmPortland

Delta flights from Portland, Maine to Greenville

Our best Delta deals on Portland, Maine to Greenville flight tickets
Delta
Jun 11
PWM6:00 amPortland
4h 57m
1 stop
GSP10:57 amGreenville
Jun 14
GSP5:30 amGreenville
9h 14m
2 stops
PWM2:44 pmPortland
Delta
Jun 11
PWM6:03 amPortland
8h 11m
2 stops
GSP2:14 pmGreenville
Jun 14
GSP11:15 amGreenville
10h 09m
2 stops
PWM9:24 pmPortland
Delta
Jun 24
PWM5:35 pmPortland
6h 20m
1 stop
GSP11:55 pmGreenville
Jun 27
GSP7:59 pmGreenville
4h 27m
1 stop
PWM12:26 amPortland

See travel insights to Greenville from

How to get the cheapest flight ticket from Portland, Maine to Greenville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Greenville?

The month of January is another great option to travel to Greenville, with average flight prices from Portland, Maine averaging around $336.

What is the cheapest day to depart on your flight to Greenville?

According to our data, Tuesday is the cheapest day to fly to Greenville from Portland, Maine. The lowest ticket price found for a Tuesday departure recently was $371. Keep in mind that prices can always vary depending on your route and whether or not you are flying domestic or international. If your travel schedule is flexible, try to avoid departing on a Sunday because tickets tend to average around $610. These prices are subject to change though, so be sure to set up a Price Alert for flights to Greenville.

What is the cheapest time of day to depart on your flight to Greenville?

Our most recent data shows that the best time of day to fly to Greenville is in the afternoon. Flights from Portland, Maine to Greenville during this time can be as low as $371. Flights to Greenville are more costly in the morning, with an average ticket price of $415. Departure times in the morning fall within the peak daily travel times, which is why tickets can be more expensive.

How have Portland, Maine to Greenville flight prices changed over time?

As of April 2025, prices for Portland, Maine to Greenville flights are approximately 6% cheaper when compared to flights at the same time last year.

When to book flights from Portland, Maine to Greenville

Are you open to changing your travel dates? Check out the ideal times to fly from Portland, Maine to Greenville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Portland, Maine to Greenville (PWM to GSP) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Portland, Maine to Greenville

Best Price Found

$136

Fastest flight time

4h 09m

Direct flights

None

Airports in Greenville

1 airport
The best one-way flight to Greenville from Portland, Maine in the past 72 hours is $136. The best round-trip flight deal from Portland, Maine to Greenville found on momondo in the last 72 hours is $284.
The fastest flight from Portland, Maine to Greenville takes 4h 09m
There are no direct flights from Portland, Maine to Greenville. Popular non-direct route for this connection is Portland Airport - Greenville Airport.
There is 1 airport near Greenville: Greenville (GSP)

  • How far is Portland to Greenville by plane?

    Portland and Greenville are 887.7 mi apart from one another. 4h 09m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Portland Airport to Greenville Airport?

    Prices for flights from Portland Airport to Greenville Airport refresh daily.

  • How many operators does momondo search for flights from Portland Airport to Greenville Airport?

  • How old do you have to be to fly from Portland Airport to Greenville Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Portland Airport to Greenville Airport.

  • What documentation or ID do you need to fly to Greenville Airport?

    The required travel and health documents for your Greenville Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Greenville Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Portland, Maine to Greenville?


Best airlines flying from Portland, Maine to Greenville

Compare and see reviews for airlines that fly from Portland, Maine to Greenville with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $276Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights
SouthwestPriceFrom $301Free CancellationRating
8.0
4,287 reviews
Search Southwest flights
DeltaPriceFrom $315Free CancellationRating
8.0
7,919 reviews
Search Delta flights

Traveling to a place near Greenville?

Book flights to Greenville if you plan to visit one of these locations
Anderson
Simpsonville
Greenwood
Seneca
Greer
Duncan

Why use momondo?

Why should I use momondo to find a flight deal from Portland to Greenville?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Portland to Greenville. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Portland to Greenville with flexible booking policies on momondo?

momondo does allow users to show only those flights to Greenville from Portland which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Portland to Greenville?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Portland to Greenville.

I’m not ready to book a flight from Portland to Greenville right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Portland to Greenville flights. All you need is a valid email address and we will do the rest; it is that quick and easy.


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