Latest deals
Insights
When to book
FAQs
Reviews
Price Alerts

Cheap flights from Panama City to Madrid from $433

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Panama City to Madrid departing on 5/4. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.

Find the cheapest flights from Panama City to Madrid

Cheap round-trip flights

KAYAK's recommended round-trip deals from the most popular airlines that fly from Panama City to Madrid.
KLM Logo
6:50 pm - 9:35 amPTY-MAD
31h 45m1 stop
KLM Logo
1:05 pm - 4:50 pmMAD-PTY
34h 45m1 stop
$697KLM
Find Deal
Tue, Jun 3 - Thu, Jun 12
 Logo
7:55 pm - 4:45 pmPTY-MAD
13h 50m1 stop
 Logo
10:20 am - 4:50 pmMAD-PTY
37h 30m1 stop
Sun, Jun 1 - Tue, Jun 10
Air France Logo
7:55 pm - 9:10 amPTY-MAD
30h 15m1 stop
Air France Logo
10:05 am - 5:45 pmMAD-PTY
14h 40m1 stop
$700Air France
Find Deal
Tue, May 27 - Mon, Jun 9
Air France Logo
7:55 pm - 11:10 pmPTY-MAD
20h 15m1 stop
Air France Logo
5:45 pm - 5:45 pmMAD-PTY
31h 00m1 stop
$711Air France
Find Deal
Sun, Jun 1 - Sat, Jun 14
Avianca Logo
3:20 am - 11:30 pmPTY-MAD
37h 10m1 stop
Avianca Logo
10:55 am - 9:00 pmMAD-PTY
16h 05m1 stop
$724Avianca
Find Deal
Tue, Oct 14 - Wed, Nov 12
Avianca Logo
3:25 am - 11:30 pmPTY-MAD
13h 05m1 stop
Avianca Logo
10:55 am - 9:00 pmMAD-PTY
16h 05m1 stop
$725Avianca
Find Deal
Mon, Oct 20 - Fri, Nov 7
Air Europa Logo
8:25 pm - 1:15 pmPTY-MAD
9h 50mnonstop
Air Europa Logo
3:05 pm - 6:40 pmMAD-PTY
10h 35mnonstop
$731Air Europa
Find Deal
Sun, Jun 1 - Tue, Jun 10
Air Europa Logo
8:25 pm - 1:15 pmPTY-MAD
9h 50mnonstop
Air Europa Logo
3:05 pm - 6:40 pmMAD-PTY
10h 35mnonstop
$742Air Europa
Find Deal
Sat, May 24 - Mon, Jun 2
Iberia Logo
5:35 pm - 10:25 amPTY-MAD
9h 50mnonstop
Iberia Logo
12:00 pm - 4:05 pmMAD-PTY
11h 05mnonstop
$754Iberia
Find Deal
Sun, Jun 1 - Mon, Jun 9
Iberia Logo
5:35 pm - 10:25 amPTY-MAD
9h 50mnonstop
Iberia Logo
12:00 pm - 4:05 pmMAD-PTY
11h 05mnonstop
$756Iberia
Find Deal
Fri, May 23 - Sun, Jun 8

Avianca flights from Panama City to Madrid

Our best Avianca deals on Panama City to Madrid flight tickets
Avianca
Oct 14
PTY3:20 amPanama City Tocumen Intl
37h 10m
1 stop
MAD11:30 pmMadrid Barajas
Nov 12
MAD10:55 amMadrid Barajas
16h 05m
1 stop
PTY9:00 pmPanama City Tocumen Intl
Avianca
Oct 20
PTY3:25 amPanama City Tocumen Intl
13h 05m
1 stop
MAD11:30 pmMadrid Barajas
Nov 7
MAD10:55 amMadrid Barajas
16h 05m
1 stop
PTY9:00 pmPanama City Tocumen Intl
Avianca
Oct 19
PTY3:20 amPanama City Tocumen Intl
13h 10m
1 stop
MAD11:30 pmMadrid Barajas
Nov 2
MAD12:35 amMadrid Barajas
15h 05m
1 stop
PTY9:40 amPanama City Tocumen Intl

Air Europa flights from Panama City to Madrid

Our best Air Europa deals on Panama City to Madrid flight tickets
Air Europa
Jun 1
PTY8:25 pmPanama City Tocumen Intl
9h 50m
MAD1:15 pmMadrid Barajas
Jun 10
MAD3:05 pmMadrid Barajas
10h 35m
PTY6:40 pmPanama City Tocumen Intl
Air Europa
May 24
PTY8:25 pmPanama City Tocumen Intl
9h 50m
MAD1:15 pmMadrid Barajas
Jun 2
MAD3:05 pmMadrid Barajas
10h 35m
PTY6:40 pmPanama City Tocumen Intl
Air Europa
Jun 2
PTY8:25 pmPanama City Tocumen Intl
9h 50m
MAD1:15 pmMadrid Barajas
Jun 10
MAD3:05 pmMadrid Barajas
10h 35m
PTY6:40 pmPanama City Tocumen Intl

See travel insights to Madrid from

How to get the cheapest flight ticket from Panama City to Madrid

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Madrid?

The month of March is, on average, the cheapest month to fly to Madrid from Panama City, with most prices found around $684. If you don’t want to visit Madrid in March, then you should wait until February to fly from Panama City, when ticket prices are also cheap, with an average price of $693.

What is the cheapest day to depart on your flight to Madrid?

The cheapest day to depart on your flight to Madrid is on a Tuesday when prices can be found for as low as $809. This is often the case because there is less demand to fly during this day of the week. Be sure to avoid booking your departure on a Wednesday as prices are generally higher than usual. According to our data, the average ticket price to Madrid on Wednesday is $864.

What is the cheapest time of day to depart on your flight to Madrid?

Flying to Madrid from Panama City in the morning is the least expensive time of day to depart. momondo users have found prices as low as $751 when looking at flights departing in the morning. Flights to Madrid are more costly at noon, with an average ticket price of $920. Departure times at noon fall within the peak daily travel times, which is why tickets can be more expensive.

What is the cheapest Panama City Tocumen Intl to Madrid Barajas flight route?

Fly from Panama City Tocumen Intl to Madrid Barajas for the best Panama City Tocumen Intl - Madrid Barajas flight prices

How far in advance should I book a flight to Madrid?

You are more likely to see cheaper flights to Madrid from Panama City when booking 21 weeks ahead of your departure date. In general, you can expect to find flights to Madrid for around $766 when searching 21 weeks out.However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Madrid from Panama City for as low as $711 on momondo.

What cabin class options are available on Panama City Tocumen Intl to Madrid Barajas flights?

There are 3 cabin classes available to choose from on Panama City Tocumen Intl to Madrid Barajas flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

How have Panama City to Madrid flight prices changed over time?

As of April 2025, prices for Panama City to Madrid flights are approximately 8% cheaper when compared to flights at the same time last year.

When to book flights from Panama City to Madrid

Are you open to changing your travel dates? Check out the ideal times to fly from Panama City to Madrid according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Panama City to Madrid (PTY to MAD) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama City to Madrid

Best Price Found

$433

Fastest flight time

9h 50m

Direct flights

Every day

Airports in Madrid

1 airport
The best one-way flight to Madrid from Panama City in the past 72 hours is $433. The best round-trip flight deal from Panama City to Madrid found on momondo in the last 72 hours is $697.
The fastest flight from Panama City to Madrid takes 9h 50m
Direct flights go from Panama City to Madrid every day.
There is 1 airport near Madrid: Madrid Barajas (MAD)

  • How far is Panama City Tocumen Intl to Madrid Barajas by plane?

    The distance between Panama City Tocumen Intl and Madrid Barajas is about 5069.0 mi. Typically, this will take 9h 50m by plane in normal conditions.

  • When did momondo last update prices for flights from Panama City Tocumen Intl Airport to Madrid Barajas Airport?

    Prices for flights from Panama City Tocumen Intl Airport to Madrid Barajas Airport were last updated today.

  • How many operators does momondo search for flights from Panama City Tocumen Intl Airport to Madrid Barajas Airport?

  • How old do you have to be to fly from Panama City Tocumen Intl Airport to Madrid Barajas Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Panama City Tocumen Intl Airport to Madrid Barajas Airport.

  • What documentation or ID do you need to fly to Madrid Barajas Airport?

    The necessary travel and health documents for your Madrid Barajas Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Panama City to Madrid?

  • What is the most popular airline from Panama City to Madrid?


Best airlines flying from Panama City to Madrid

Compare and see reviews for airlines that fly from Panama City to Madrid with momondo
Airline
Rating
Free Cancellation
Price
AviancaPriceFrom $543Free CancellationRating
6.7
2,319 reviews
Search Avianca flights
Air EuropaPriceFrom $644Free CancellationRating
6.9
509 reviews
Search Air Europa flights
IberiaPriceFrom $645Free CancellationRating
7.0
2,684 reviews
Search Iberia flights
Air FrancePriceFrom $669Free CancellationRating
7.4
1,442 reviews
Search Air France flights
KLMPriceFrom $670Free CancellationRating
7.8
1,333 reviews
Search KLM flights
United AirlinesPriceFrom $678Free CancellationRating
7.4
8,685 reviews
Search United Airlines flights
Turkish AirlinesPriceFrom $735Free CancellationRating
7.3
3,774 reviews
Search Turkish Airlines flights
  • Iberia Flights From Panama City to Madrid

    Across 3 Iberia flights from Panama City to Madrid this week, the average price was $820, with the best Iberia deals starting from $645 round-trip. 2,684 users have rated Iberia on momondo, with an average score of 7.0/10.

  • Air Europa Flights From Panama City to Madrid

    Another popular option for Panama City to Madrid flights is Air Europa (6.9/10, 509 ratings). Air Europa flies from Panama City to Madrid around 6 times per week, with deals starting from $644 round-trip and rising to an average price of around $778.


Traveling to a place near Madrid?

Book flights to Madrid if you plan to visit one of these locations
Toledo
Segovia
Getafe
Fuenlabrada
San Lorenzo de El Escorial
Cuenca
Guadalajara
El Arenal

Why use momondo?

Why should I use momondo to find a flight deal from Panama City to Madrid?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Panama City to Madrid. momondo saves you time and could save you money on your trip.

Can I find flights from Panama City to Madrid with flexible booking policies on momondo?

Flights from Panama City to Madrid with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Panama City to Madrid?

momondo helps you find the best flight between Panama City and Madrid by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Panama City to Madrid right now. Can momondo alert me if prices change?

Price alerts on flights to Madrid from Panama City are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.


An easier way to manage your Madrid trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
From?
To?
Mon 4/28
Mon 5/5

Find better results for your trip to Spain

Fly your favorite airline to Madrid

Airlines are sorted and displayed according to clicks in the past 7 days on momondo