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Cheap flights from Panama City to Madrid from $443

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Panama City to Madrid departing on 3/18. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Panama City to Madrid

Cheap round-trip flights

These are some of the best round-trip flight deals from Panama City to Madrid that have been recently found on momondo from popular airlines, departing in the coming months.
6:50 pm - 1:40 pmPTY-MAD
35h 50m1 stop
6:00 am - 4:50 pmMAD-PTY
17h 50m1 stop
$676KLM
Find Deal
Mon, May 26 - Mon, Jun 16
6:45 pm - 10:15 amPTY-MAD
33h 30m1 stop
1:00 pm - 4:25 pmMAD-PTY
33h 25m1 stop
$683KLM
Find Deal
Wed, Mar 5 - Wed, Mar 26
5:35 pm - 10:25 amPTY-MAD
9h 50mnonstop
12:00 pm - 4:05 pmMAD-PTY
11h 05mnonstop
$687Iberia
Find Deal
Sat, May 17 - Sat, May 24
5:35 pm - 10:25 amPTY-MAD
9h 50mnonstop
12:00 pm - 4:05 pmMAD-PTY
11h 05mnonstop
$690Iberia
Find Deal
Fri, May 9 - Fri, May 30
7:55 pm - 4:45 pmPTY-MAD
13h 50m1 stop
10:20 am - 4:50 pmMAD-PTY
37h 30m1 stop
Sun, May 18 - Wed, May 28
7:55 pm - 4:45 pmPTY-MAD
13h 50m1 stop
6:00 am - 4:50 pmMAD-PTY
17h 50m1 stop
Mon, May 19 - Sat, May 31
9:30 pm - 1:05 pmPTY-MAD
9h 35mnonstop
3:05 pm - 6:40 pmMAD-PTY
10h 35mnonstop
$704Air Europa
Find Deal
Mon, Mar 24 - Mon, May 12
9:30 pm - 1:05 pmPTY-MAD
9h 35mnonstop
3:05 pm - 6:40 pmMAD-PTY
10h 35mnonstop
$705Air Europa
Find Deal
Mon, Mar 24 - Sat, May 3
8:05 am - 9:35 amPTY-MAD
18h 30m1 stop
10:05 am - 5:45 pmMAD-PTY
14h 40m1 stop
$710Air France
Find Deal
Sat, May 10 - Sat, May 31
8:05 am - 9:35 amPTY-MAD
18h 30m1 stop
10:05 am - 5:45 pmMAD-PTY
14h 40m1 stop
$744Air France
Find Deal
Sat, May 17 - Sat, May 24

KLM flights from Panama City to Madrid

Our best KLM deals on Panama City to Madrid flight tickets
KLM
May 26
PTY6:50 pmPanama City Tocumen Intl
35h 50m
1 stop
MAD1:40 pmMadrid Barajas
Jun 16
MAD6:00 amMadrid Barajas
17h 50m
1 stop
PTY4:50 pmPanama City Tocumen Intl
KLM
Mar 5
PTY6:45 pmPanama City Tocumen Intl
33h 30m
1 stop
MAD10:15 amMadrid Barajas
Mar 26
MAD1:00 pmMadrid Barajas
33h 25m
1 stop
PTY4:25 pmPanama City Tocumen Intl
KLM
Jul 3
PTY6:50 pmPanama City Tocumen Intl
14h 35m
1 stop
MAD4:25 pmMadrid Barajas
Aug 21
MAD10:20 amMadrid Barajas
37h 30m
1 stop
PTY4:50 pmPanama City Tocumen Intl

Iberia flights from Panama City to Madrid

Our best Iberia deals on Panama City to Madrid flight tickets
Iberia
May 17
PTY5:35 pmPanama City Tocumen Intl
9h 50m
MAD10:25 amMadrid Barajas
May 24
MAD12:00 pmMadrid Barajas
11h 05m
PTY4:05 pmPanama City Tocumen Intl
Iberia
May 9
PTY5:35 pmPanama City Tocumen Intl
9h 50m
MAD10:25 amMadrid Barajas
May 30
MAD12:00 pmMadrid Barajas
11h 05m
PTY4:05 pmPanama City Tocumen Intl
Iberia
May 10
PTY5:35 pmPanama City Tocumen Intl
9h 50m
MAD10:25 amMadrid Barajas
Jun 1
MAD12:00 pmMadrid Barajas
11h 05m
PTY4:05 pmPanama City Tocumen Intl

See travel insights to Madrid from

How to get the cheapest flight ticket from Panama City to Madrid

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Madrid?

The month of March is, on average, the cheapest month to fly to Madrid from Panama City, with most prices found around $692. If you don’t want to visit Madrid in March, then you should wait until February to fly from Panama City, when ticket prices are also cheap, with an average price of $694.

What is the cheapest day to depart on your flight to Madrid?

The cheapest day to depart on your flight to Madrid is on a Tuesday when prices can be found for as low as $810. This is often the case because there is less demand to fly during this day of the week. Be sure to avoid booking your departure on a Wednesday as prices are generally higher than usual. According to our data, the average ticket price to Madrid on Wednesday is $863.

What is the cheapest time of day to depart on your flight to Madrid?

Flying to Madrid from Panama City in the morning is the least expensive time of day to depart. momondo users have found prices as low as $751 when looking at flights departing in the morning. Flights to Madrid are more costly at noon, with an average ticket price of $920. Departure times at noon fall within the peak daily travel times, which is why tickets can be more expensive.

What is the cheapest Panama City Tocumen Intl to Madrid Barajas flight route?

Fly from Panama City Tocumen Intl to Madrid Barajas for the best Panama City Tocumen Intl - Madrid Barajas flight prices

How far in advance should I book a flight to Madrid?

You are more likely to see cheaper flights to Madrid from Panama City when booking 26 weeks ahead of your departure date. In general, you can expect to find flights to Madrid for around $770 when searching 26 weeks out.However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Madrid from Panama City for as low as $716 on momondo.

What cabin class options are available on Panama City Tocumen Intl to Madrid Barajas flights?

There are 3 cabin classes available to choose from on Panama City Tocumen Intl to Madrid Barajas flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

How have Panama City to Madrid flight prices changed over time?

As of February 2025, prices for Panama City to Madrid flights are approximately 4% cheaper when compared to flights at the same time last year.

When to book flights from Panama City to Madrid

Are you open to changing your travel dates? Check out the ideal times to fly from Panama City to Madrid according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Panama City to Madrid (PTY to MAD) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama City to Madrid

Best Price Found

$443

Fastest flight time

9h 35m

Direct flights

Every day

Airports in Madrid

1 airport
The best one-way flight to Madrid from Panama City in the past 72 hours is $443. The best round-trip flight deal from Panama City to Madrid found on momondo in the last 72 hours is $676.
The fastest flight from Panama City to Madrid takes 9h 35m
Direct flights go from Panama City to Madrid every day.
There is 1 airport near Madrid: Madrid Barajas (MAD)

  • How far is Panama City Tocumen Intl to Madrid Barajas by plane?

    The distance between Panama City Tocumen Intl and Madrid Barajas is about 5069.0 mi. Typically, this will take 9h 35m by plane in normal conditions.

  • When did momondo last update prices for flights from Panama City Tocumen Intl Airport to Madrid Barajas Airport?

    Prices for flights from Panama City Tocumen Intl Airport to Madrid Barajas Airport were last updated today.

  • How many operators does momondo search for flights from Panama City Tocumen Intl Airport to Madrid Barajas Airport?

  • How old do you have to be to fly from Panama City Tocumen Intl Airport to Madrid Barajas Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Panama City Tocumen Intl Airport to Madrid Barajas Airport.

  • What documentation or ID do you need to fly to Madrid Barajas Airport?

    The necessary travel and health documents for your Madrid Barajas Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Panama City to Madrid?

  • What is the most popular airline from Panama City to Madrid?


Best airlines flying from Panama City to Madrid

Compare and see reviews for airlines that fly from Panama City to Madrid with momondo
Airline
Rating
Free Cancellation
Price
AviancaPriceFrom $543Free CancellationRating
6.8
2,435 reviews
Search Avianca flights
United AirlinesPriceFrom $601Free CancellationRating
7.4
8,765 reviews
Search United Airlines flights
Air EuropaPriceFrom $647Free CancellationRating
6.9
517 reviews
Search Air Europa flights
IberiaPriceFrom $656Free CancellationRating
7.0
2,639 reviews
Search Iberia flights
Air FrancePriceFrom $666Free CancellationRating
7.4
1,449 reviews
Search Air France flights
KLMPriceFrom $670Free CancellationRating
7.8
1,333 reviews
Search KLM flights
Turkish AirlinesPriceFrom $728Free CancellationRating
7.3
3,832 reviews
Search Turkish Airlines flights
  • Iberia Flights From Panama City to Madrid

    Across 2 Iberia flights from Panama City to Madrid this week, the average price was $828, with the best Iberia deals starting from $656 round-trip. 2,639 users have rated Iberia on momondo, with an average score of 7.0/10.

  • Air Europa Flights From Panama City to Madrid

    Another popular option for Panama City to Madrid flights is Air Europa (6.9/10, 517 ratings). Air Europa flies from Panama City to Madrid around 2 times per week, with deals starting from $647 round-trip and rising to an average price of around $778.


Traveling to a place near Madrid?

Book flights to Madrid if you plan to visit one of these locations
Toledo
Segovia
Getafe
Fuenlabrada
San Lorenzo de El Escorial
Cuenca
Guadalajara
El Arenal

Why use momondo?

Why should I use momondo to find a flight deal from Panama City to Madrid?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Panama City to Madrid. momondo saves you time and could save you money on your trip.

Can I find flights from Panama City to Madrid with flexible booking policies on momondo?

Flights from Panama City to Madrid with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Panama City to Madrid?

momondo helps you find the best flight between Panama City and Madrid by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Panama City to Madrid right now. Can momondo alert me if prices change?

Price alerts on flights to Madrid from Panama City are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.


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