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Cheap flights from Chicago O'Hare Intl Airport to Greenville from $110

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Chicago O'Hare Intl Airport to Greenville departing on 1/29. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Chicago O'Hare Intl Airport to Greenville

Cheap round-trip flights

These are some of the best round-trip flight deals from Chicago O'Hare Intl Airport to Greenville that have been recently found on momondo from popular airlines, departing in the coming months.

Cheap one-way flights

Flying one-way? These are some of the best deals recently discovered on momondo for flights from Chicago O'Hare Intl Airport to Greenville.

Cheap last minute flights

Planning a quick getaway from Chicago O'Hare Intl Airport to Greenville? These are the last-minute flight deals available now.

Cheap direct flights

If you prefer a non-stop journey, check out our latest direct flight deals to Greenville, so you can enjoy a seamless trip without layovers.

Cheap bus & train deals from Chicago O'Hare Intl Airport to Greenville

Find recent round-trip train or bus tickets from Chicago O'Hare Intl Airport to Greenville.

All round-trip flight deals from Chicago O'Hare Intl Airport to Greenville

The cheapest plane tickets from Chicago O'Hare Intl Airport to Greenville found on KAYAK recently.
5:52 pm - 8:38 pmORD-GSP
1h 46mnonstop
7:45 am - 8:50 amGSP-ORD
2h 05mnonstop
$219American Airlines
Find Deal
Sat, Feb 22 - Tue, Feb 25
6:15 pm - 9:14 pmORD-GSP
1h 59mnonstop
2:53 pm - 6:52 pmGSP-ORD
4h 59m1 stop
$229United Airlines
Find Deal
Sat, Feb 15 - Sat, Feb 22
5:13 pm - 11:46 pmORD-GSP
5h 33m1 stop
11:54 am - 3:43 pmGSP-ORD
4h 49m1 stop
$239Delta
Find Deal
Sat, Feb 22 - Tue, Feb 25
6:55 pm - 10:01 pmORD-GSP
2h 06mnonstop
7:45 am - 8:50 amGSP-ORD
2h 05mnonstop
$249American Airlines
Find Deal
Fri, Feb 21 - Tue, Feb 25
6:55 pm - 9:53 pmORD-GSP
1h 58mnonstop
11:46 am - 12:55 pmGSP-ORD
2h 09mnonstop
$252American Airlines
Find Deal
Wed, Apr 23 - Sat, Apr 26
11:53 am - 5:31 pmORD-GSP
4h 38m1 stop
7:45 am - 8:50 amGSP-ORD
2h 05mnonstop
$259American Airlines
Find Deal
Sat, Feb 22 - Tue, Feb 25
9:35 am - 2:19 pmORD-GSP
3h 44m1 stop
7:20 pm - 11:49 pmGSP-ORD
5h 29m1 stop
$269Delta
Find Deal
Tue, Mar 4 - Fri, Mar 7
11:25 am - 8:40 pmORD-GSP
8h 15m1 stop
11:30 am - 9:30 pmGSP-ORD
11h 00m2 stops
$304Southwest
Find Deal
Thu, Feb 6 - Mon, Feb 10
11:05 am - 2:00 pmORD-GSP
1h 55mnonstop
6:30 am - 7:53 amGSP-ORD
2h 23mnonstop
$319United Airlines
Find Deal
Tue, Mar 4 - Thu, Mar 13
1:50 pm - 8:20 pmORD-GSP
5h 30m1 stop
7:05 am - 4:45 pmGSP-ORD
10h 40m2 stops
$333Southwest
Find Deal
Wed, Apr 23 - Sat, Apr 26
5:30 pm - 8:24 pmORD-GSP
1h 54mnonstop
$110American Airlines
Find Deal
Wed, Jan 29
12:35 pm - 10:07 pmORD-GSP
8h 32m1 stop
$120Delta
Find Deal
Tue, Feb 18
9:00 am - 11:51 amORD-GSP
1h 51mnonstop
$140American Airlines
Find Deal
Sun, Feb 16
6:15 pm - 9:14 pmORD-GSP
1h 59mnonstop
$145United Airlines
Find Deal
Tue, Feb 18
5:30 pm - 11:33 pmORD-GSP
5h 03m1 stop
$150Delta
Find Deal
Sat, Mar 15
5:11 am - 4:18 pmORD-GSP
10h 07m1 stop
Mon, Jan 27
7:00 am - 8:50 pmORD-GSP
12h 50m2 stops
$160Southwest
Find Deal
Tue, Feb 4
5:11 am - 4:18 pmORD-GSP
10h 07m1 stop
Mon, Feb 3
6:15 pm - 9:14 pmORD-GSP
1h 59mnonstop
$175United Airlines
Find Deal
Mon, Feb 17
7:30 am - 5:40 pmORD-GSP
9h 10m2 stops
$184Southwest
Find Deal
Tue, Apr 15
7:26 am - 1:54 pmORD-GSP
5h 28m1 stop
10:03 am - 6:18 pmGSP-ORD
9h 15m1 stop
Sun, Jan 19 - Thu, Feb 20
7:26 am - 1:54 pmORD-GSP
5h 28m1 stop
10:03 am - 11:58 pmGSP-ORD
14h 55m2 stops
Sun, Jan 19 - Thu, Feb 20
7:26 am - 1:54 pmORD-GSP
5h 28m1 stop
10:03 am - 12:37 pmGSP-ORD
27h 34m3 stops
Sun, Jan 19 - Thu, Feb 20
6:35 pm - 9:44 pmORD-GSP
2h 09mnonstop
6:30 am - 7:53 amGSP-ORD
2h 23mnonstop
$504United Airlines
Find Deal
Sun, Jan 19 - Thu, Feb 20
6:35 pm - 9:44 pmORD-GSP
2h 09mnonstop
10:05 am - 2:03 pmGSP-ORD
4h 58m1 stop
$514United Airlines
Find Deal
Sun, Jan 19 - Thu, Feb 20
4:02 pm - 10:30 pmORD-GSP
5h 28m1 stop
6:42 am - 12:30 pmGSP-ORD
6h 48m1 stop
$643American Airlines
Find Deal
Fri, Jan 17 - Tue, Jan 21
7:30 am - 8:50 pmORD-GSP
12h 20m2 stops
8:25 am - 2:00 pmGSP-ORD
6h 35m1 stop
$684Southwest
Find Deal
Sun, Jan 19 - Tue, Jan 21
7:00 am - 3:20 pmORD-GSP
7h 20m2 stops
11:00 am - 10:20 pmGSP-ORD
12h 20m2 stops
$689Southwest
Find Deal
Sat, Jan 18 - Tue, Jan 21
5:30 pm - 8:24 pmORD-GSP
1h 54mnonstop
7:00 am - 8:15 amGSP-ORD
2h 15mnonstop
$773American Airlines
Find Deal
Sun, Jan 19 - Wed, Jan 22
6:45 am - 6:35 pmORD-GSP
10h 50m2 stops
11:59 am - 6:41 pmGSP-ORD
7h 42m1 stop
$1,311Delta
Find Deal
Fri, Jan 17 - Tue, Jan 21
5:52 pm - 8:38 pmORD-GSP
1h 46mnonstop
7:45 am - 8:50 amGSP-ORD
2h 05mnonstop
$219American Airlines
Find Deal
Sat, Feb 22 - Tue, Feb 25
6:55 pm - 10:01 pmORD-GSP
2h 06mnonstop
7:45 am - 8:50 amGSP-ORD
2h 05mnonstop
$249American Airlines
Find Deal
Fri, Feb 21 - Tue, Feb 25
6:55 pm - 9:53 pmORD-GSP
1h 58mnonstop
11:46 am - 12:55 pmGSP-ORD
2h 09mnonstop
$252American Airlines
Find Deal
Wed, Apr 23 - Sat, Apr 26
5:30 pm - 8:15 pmORD-GSP
1h 45mnonstop
7:50 am - 8:55 amGSP-ORD
2h 05mnonstop
$278American Airlines
Find Deal
Wed, Feb 19 - Sun, Feb 23
7:00 pm - 9:51 pmORD-GSP
1h 51mnonstop
7:50 am - 9:01 amGSP-ORD
2h 11mnonstop
$279American Airlines
Find Deal
Mon, Mar 31 - Sat, Apr 5
5:52 pm - 8:38 pmORD-GSP
1h 46mnonstop
8:00 am - 9:05 amGSP-ORD
2h 05mnonstop
$280American Airlines
Find Deal
Sat, Mar 1 - Sat, Mar 8
6:55 pm - 9:53 pmORD-GSP
1h 58mnonstop
7:50 am - 9:01 amGSP-ORD
2h 11mnonstop
$284American Airlines
Find Deal
Sat, Apr 19 - Sun, Apr 27
11:05 am - 2:00 pmORD-GSP
1h 55mnonstop
5:32 pm - 6:55 pmGSP-ORD
2h 23mnonstop
$289United Airlines
Find Deal
Tue, Mar 4 - Tue, Mar 11
5:52 pm - 8:38 pmORD-GSP
1h 46mnonstop
8:00 am - 9:05 amGSP-ORD
2h 05mnonstop
$292American Airlines
Find Deal
Sat, Mar 1 - Sat, Mar 8
11:05 am - 2:00 pmORD-GSP
1h 55mnonstop
6:30 am - 7:53 amGSP-ORD
2h 23mnonstop
$319United Airlines
Find Deal
Tue, Mar 4 - Thu, Mar 13

American Airlines flights from Chicago O'Hare Intl Airport to Greenville

Our best American Airlines deals on Chicago O'Hare Intl Airport to Greenville flight tickets
American Airlines
Feb 22
ORD5:52 pmChicago O'Hare Intl
1h 46m
GSP8:38 pmGreenville
Feb 25
GSP7:45 amGreenville
2h 05m
ORD8:50 amChicago O'Hare Intl
American Airlines
Feb 21
ORD6:55 pmChicago O'Hare Intl
2h 06m
GSP10:01 pmGreenville
Feb 25
GSP7:45 amGreenville
2h 05m
ORD8:50 amChicago O'Hare Intl
American Airlines
Apr 23
ORD6:55 pmChicago O'Hare Intl
1h 58m
GSP9:53 pmGreenville
Apr 26
GSP11:46 amGreenville
2h 09m
ORD12:55 pmChicago O'Hare Intl

Delta flights from Chicago O'Hare Intl Airport to Greenville

Our best Delta deals on Chicago O'Hare Intl Airport to Greenville flight tickets
Delta
Feb 22
ORD5:13 pmChicago O'Hare Intl
5h 33m
1 stop
GSP11:46 pmGreenville
Feb 25
GSP11:54 amGreenville
4h 49m
1 stop
ORD3:43 pmChicago O'Hare Intl
Delta
Mar 4
ORD9:35 amChicago O'Hare Intl
3h 44m
1 stop
GSP2:19 pmGreenville
Mar 7
GSP7:20 pmGreenville
5h 29m
1 stop
ORD11:49 pmChicago O'Hare Intl
Delta
Feb 19
ORD11:15 amChicago O'Hare Intl
6h 17m
1 stop
GSP6:32 pmGreenville
Feb 23
GSP7:00 amGreenville
6h 55m
1 stop
ORD12:55 pmChicago O'Hare Intl

See travel insights to Greenville from

How to get the cheapest flight ticket from Chicago O'Hare Intl Airport to Greenville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Greenville?

The month of January is another great option to travel to Greenville, with average flight prices from Chicago O'Hare Intl Airport averaging around $306.

What is the cheapest day to depart on your flight to Greenville?

According to our data, Wednesday is the cheapest day to fly to Greenville from Chicago O'Hare Intl Airport. The lowest ticket price found for a Wednesday departure recently was $312. Keep in mind that prices can always vary depending on your route and whether or not you are flying domestic or international. If your travel schedule is flexible, try to avoid departing on a Sunday because tickets tend to average around $398. These prices are subject to change though, so be sure to set up a Price Alert for flights to Greenville.

What is the cheapest time of day to depart on your flight to Greenville?

Our most recent data shows that the best time of day to fly to Greenville is in the evening. Flights from Chicago O'Hare Intl Airport to Greenville during this time can be as low as $299. Flights to Greenville are more costly at noon, with an average ticket price of $351. Departure times at noon fall within the peak daily travel times, which is why tickets can be more expensive.

What is the cheapest Chicago O'Hare Intl to Greenville flight route?

Fly from Chicago O'Hare Intl to Greenville for the best Chicago O'Hare Intl - Greenville flight prices

How far in advance should I book a flight to Greenville?

You are more likely to see cheaper flights to Greenville from Chicago O'Hare Intl Airport when booking 13 weeks ahead of your departure date. In general, you can expect to find flights to Greenville for around $327 when searching 13 weeks out.However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Greenville from Chicago O'Hare Intl Airport for as low as $249 on momondo.

What cabin class options are available on Chicago O'Hare Intl to Greenville flights?

There are 4 cabin classes available to choose from on Chicago O'Hare Intl to Greenville flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

How have Chicago O'Hare Intl Airport to Greenville flight prices changed over time?

As of January 2025, prices for Chicago O'Hare Intl Airport to Greenville flights are approximately 0% more expensive when compared to flights at the same time last year.

When to book flights from Chicago O'Hare Intl Airport to Greenville

Are you open to changing your travel dates? Check out the ideal times to fly from Chicago O'Hare Intl Airport to Greenville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Chicago O'Hare Intl Airport to Greenville (ORD to GSP) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Chicago O'Hare Intl Airport to Greenville

Best Price Found

$110

Fastest flight time

1h 44m

Direct flights

Every day

Airports in Greenville

1 airport
The best one-way flight to Greenville from Chicago O'Hare Intl Airport in the past 72 hours is $110. The best round-trip flight deal from Chicago O'Hare Intl Airport to Greenville found on momondo in the last 72 hours is $219.
The fastest flight from Chicago O'Hare Intl Airport to Greenville takes 1h 44m
Direct flights go from Chicago O'Hare Intl Airport to Greenville every day.
There is 1 airport near Greenville: Greenville (GSP)

  • How far is Chicago O'Hare Intl to Greenville by plane?

    Chicago O'Hare Intl and Greenville are 575.0 mi apart from one another. Typically, this will take 1h 44m by plane in normal conditions.

  • When did momondo last update prices for flights from Chicago O'Hare Intl Airport to Greenville Airport?

    Prices for flights from Chicago O'Hare Intl Airport to Greenville Airport were last updated today.

  • How many operators does momondo search for flights from Chicago O'Hare Intl Airport to Greenville Airport?

  • How old do you have to be to fly from Chicago O'Hare Intl Airport to Greenville Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Chicago O'Hare Intl Airport to Greenville Airport.

  • What documentation or ID do you need to fly to Greenville Airport?

    The necessary travel and health documents for your Greenville Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Chicago O'Hare Intl Airport to Greenville?

  • What is the most popular airline from Chicago O'Hare Intl Airport to Greenville?


Best airlines flying from Chicago O'Hare Intl Airport to Greenville

Compare and see reviews for airlines that fly from Chicago O'Hare Intl Airport to Greenville with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $209Free CancellationRating
7.4
8,965 reviews
Search United Airlines flights
American AirlinesPriceFrom $233Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights
  • United Airlines Flights From Chicago O'Hare Intl Airport to Greenville

    United Airlines flight deals from Chicago O'Hare Intl Airport to Greenville start from $209 round-trip. Over the 13 United Airlines flights for this route in a normal week, average airfare is usually $386 round-trip - but some users have found much cheaper deals with momondo.

  • American Airlines Flights From Chicago O'Hare Intl Airport to Greenville

    The best American Airlines deal for Chicago O'Hare Intl Airport to Greenville flight tickets found on momondo in the last 72 hours was $233, round-trip. It should be noted that an average American Airlines flight deal for this route in this time was higher, at $314 round-trip. American Airlines operates 5 flights out of Chicago O'Hare Intl Airport into Greenville in an average week, so prices vary by time and availability. 10,000 American Airlines reviews by users on momondo have scored the airline at 7.2/10.


Traveling to a place near Greenville?

Book flights to Greenville if you plan to visit one of these locations
Anderson
Simpsonville
Greenwood
Seneca
Greer
Duncan

Why use momondo?

Why should I use momondo to find a flight deal from Chicago to Greenville?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Chicago to Greenville. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Chicago to Greenville with flexible booking policies on momondo?

momondo does allow users to show only those flights to Greenville from Chicago which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Chicago to Greenville?

momondo provides multiple filters to help you find the best flight to Greenville from Chicago. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Chicago to Greenville right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Chicago to Greenville flights. All you need is a valid email address and we will do the rest; it is that quick and easy.


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