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Cheap flights from Madrid to Panama City from $420

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Madrid to Panama City departing on 1/27. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Madrid to Panama City

Cheap round-trip flights

These are some of the best round-trip flight deals from Madrid to Panama City that have been recently found on momondo from popular airlines, departing in the coming months.

Cheap one-way flights

Flying one-way? These are some of the best deals recently discovered on momondo for flights from Madrid to Panama City.

Cheap last minute flights

Planning a quick getaway from Madrid to Panama City? These are the last-minute flight deals available now.

Cheap direct flights

If you prefer a non-stop journey, check out our latest direct flight deals to Panama City, so you can enjoy a seamless trip without layovers.

Cheap bus & train deals from Madrid to Panama City

Find recent round-trip train or bus tickets from Madrid to Panama City.

All round-trip flight deals to Panama City

The cheapest plane tickets to Panama City found on KAYAK recently.
6:00 am - 4:25 pmMAD-PTY
16h 25m1 stop
6:45 pm - 10:15 amPTY-MAD
33h 30m1 stop
$587KLM
Find Deal
Wed, Feb 5 - Mon, Feb 17
8:35 pm - 6:50 pmMAD-PTY
28h 15m2 stops
6:45 pm - 11:25 pmPTY-MAD
22h 40m1 stop
$612KLM
Find Deal
Mon, Feb 3 - Sun, Feb 9
6:00 am - 4:50 pmMAD-PTY
17h 50m1 stop
8:05 am - 10:25 amPTY-MAD
19h 20m1 stop
Fri, Apr 25 - Sun, May 4
6:00 am - 4:50 pmMAD-PTY
17h 50m1 stop
8:05 am - 10:25 amPTY-MAD
19h 20m1 stop
Fri, Apr 25 - Sun, May 4
3:10 pm - 7:45 pmMAD-PTY
10h 35mnonstop
9:30 pm - 1:05 pmPTY-MAD
9h 35mnonstop
$659Air Europa
Find Deal
Tue, Mar 11 - Sun, Mar 23
3:10 pm - 7:45 pmMAD-PTY
10h 35mnonstop
9:30 pm - 1:05 pmPTY-MAD
9h 35mnonstop
$684Air Europa
Find Deal
Mon, Mar 10 - Mon, Mar 17
11:45 am - 4:50 pmMAD-PTY
11h 05mnonstop
6:20 pm - 10:25 amPTY-MAD
10h 05mnonstop
$755Iberia
Find Deal
Tue, Feb 11 - Fri, Feb 21
11:45 am - 4:50 pmMAD-PTY
11h 05mnonstop
6:20 pm - 10:25 amPTY-MAD
10h 05mnonstop
$803Iberia
Find Deal
Tue, Jan 21 - Thu, Feb 6
12:35 am - 9:40 amMAD-PTY
15h 05m1 stop
11:25 am - 8:55 amPTY-MAD
15h 30m1 stop
$955Avianca
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Tue, Feb 4 - Mon, Feb 17
12:35 am - 9:40 amMAD-PTY
15h 05m1 stop
11:25 am - 6:30 amPTY-MAD
13h 05m1 stop
$962Avianca
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Sun, Feb 2 - Mon, Feb 17
10:25 pm - 8:00 pmMAD-PTY
51h 35m2 stops
Mon, Jan 27
4:25 pm - 8:00 pmMAD-PTY
33h 35m2 stops
Tue, Jan 28
3:10 pm - 7:45 pmMAD-PTY
10h 35mnonstop
$434Air Europa
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Fri, Feb 28
3:10 pm - 7:45 pmMAD-PTY
10h 35mnonstop
$440Air Europa
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Wed, Feb 26
12:35 am - 9:40 amMAD-PTY
15h 05m1 stop
$475Avianca
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Sun, Jan 26
10:55 am - 12:20 amMAD-PTY
19h 25m1 stop
$483Avianca
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Tue, Jan 7
10:55 am - 1:00 amMAD-PTY
20h 05m1 stop
$485Avianca
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Thu, Jan 16
11:45 am - 4:50 pmMAD-PTY
11h 05mnonstop
$563Iberia
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Sun, Mar 9
6:00 am - 6:50 pmMAD-PTY
18h 50m2 stops
$684KLM
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Tue, Feb 25
11:45 am - 4:50 pmMAD-PTY
11h 05mnonstop
$987Iberia
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Thu, Jan 16
12:35 am - 9:40 amMAD-PTY
15h 05m1 stop
5:40 pm - 2:05 pmPTY-MAD
13h 25m1 stop
$1,225Avianca
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Sun, Dec 29 - Sat, Oct 11
11:00 am - 1:55 pmMAD-PTY
32h 55m1 stop
3:27 pm - 8:00 amPTY-MAD
34h 33m2 stops
$1,252Delta
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Fri, Dec 27 - Wed, Jan 8
1:45 am - 4:11 pmMAD-PTY
20h 26m1 stop
8:25 pm - 1:15 pmPTY-MAD
9h 50mnonstop
$1,302
Find Deal
Sun, Dec 29 - Sat, Oct 11
3:15 am - 2:27 pmMAD-PTY
17h 12m2 stops
9:30 pm - 1:05 pmPTY-MAD
9h 35mnonstop
$1,447
Find Deal
Mon, Dec 30 - Sun, Jan 19
11:15 am - 2:45 pmMAD-PTY
33h 30m2 stops
10:00 am - 11:45 amPTY-MAD
19h 45m2 stops
$1,547United Airlines
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Fri, Dec 27 - Fri, Jan 3
3:10 pm - 7:45 pmMAD-PTY
10h 35mnonstop
8:25 pm - 1:15 pmPTY-MAD
9h 50mnonstop
$1,606Air Europa
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Mon, Dec 30 - Sat, Oct 11
11:15 am - 5:07 pmMAD-PTY
35h 52m2 stops
11:55 pm - 9:35 amPTY-MAD
27h 40m2 stops
$1,754United Airlines
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Fri, Dec 27 - Mon, Jan 6
3:10 pm - 7:45 pmMAD-PTY
10h 35mnonstop
9:30 pm - 1:05 pmPTY-MAD
9h 35mnonstop
$1,992Air Europa
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Thu, Dec 26 - Thu, Jan 2
6:10 am - 6:20 pmMAD-PTY
42h 10m2 stops
7:50 pm - 11:30 pmPTY-MAD
21h 40m1 stop
$2,734Turkish Airlines
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Thu, Dec 26 - Thu, Jan 2
5:40 pm - 6:20 pmMAD-PTY
30h 40m2 stops
9:45 pm - 10:25 amPTY-MAD
30h 40m1 stop
$4,477Turkish Airlines
Find Deal
Sat, Dec 28 - Fri, Jan 3
3:10 pm - 7:45 pmMAD-PTY
10h 35mnonstop
9:30 pm - 1:05 pmPTY-MAD
9h 35mnonstop
$659Air Europa
Find Deal
Tue, Mar 11 - Sun, Mar 23
3:10 pm - 7:45 pmMAD-PTY
10h 35mnonstop
9:30 pm - 1:05 pmPTY-MAD
9h 35mnonstop
$684Air Europa
Find Deal
Mon, Mar 10 - Mon, Mar 17
3:05 pm - 6:40 pmMAD-PTY
10h 35mnonstop
8:25 pm - 1:15 pmPTY-MAD
9h 50mnonstop
$685Air Europa
Find Deal
Sat, Apr 26 - Tue, May 6
3:10 pm - 7:45 pmMAD-PTY
10h 35mnonstop
9:30 pm - 1:05 pmPTY-MAD
9h 35mnonstop
$700Air Europa
Find Deal
Fri, Feb 21 - Sat, Mar 15
3:10 pm - 7:45 pmMAD-PTY
10h 35mnonstop
9:30 pm - 1:05 pmPTY-MAD
9h 35mnonstop
$713Air Europa
Find Deal
Tue, Jan 21 - Sun, Feb 23
3:05 pm - 6:40 pmMAD-PTY
10h 35mnonstop
8:25 pm - 1:15 pmPTY-MAD
9h 50mnonstop
$740Air Europa
Find Deal
Tue, Apr 22 - Fri, May 9
3:05 pm - 6:40 pmMAD-PTY
10h 35mnonstop
8:25 pm - 1:15 pmPTY-MAD
9h 50mnonstop
$741Air Europa
Find Deal
Tue, Apr 1 - Wed, Apr 30
3:05 pm - 6:40 pmMAD-PTY
10h 35mnonstop
8:25 pm - 1:15 pmPTY-MAD
9h 50mnonstop
$743Air Europa
Find Deal
Tue, Apr 1 - Wed, Apr 30
11:45 am - 4:50 pmMAD-PTY
11h 05mnonstop
6:20 pm - 10:25 amPTY-MAD
10h 05mnonstop
$755Iberia
Find Deal
Tue, Feb 11 - Fri, Feb 21
11:45 am - 4:50 pmMAD-PTY
11h 05mnonstop
6:20 pm - 10:25 amPTY-MAD
10h 05mnonstop
$803Iberia
Find Deal
Tue, Jan 21 - Thu, Feb 6

Air Europa flights from Madrid to Panama City

Our best Air Europa deals on Madrid to Panama City flight tickets
Air Europa
Mar 11
MAD3:10 pmMadrid Barajas
10h 35m
PTY7:45 pmPanama City Tocumen Intl
Mar 23
PTY9:30 pmPanama City Tocumen Intl
9h 35m
MAD1:05 pmMadrid Barajas
Air Europa
Mar 10
MAD3:10 pmMadrid Barajas
10h 35m
PTY7:45 pmPanama City Tocumen Intl
Mar 17
PTY9:30 pmPanama City Tocumen Intl
9h 35m
MAD1:05 pmMadrid Barajas
Air Europa
Apr 26
MAD3:05 pmMadrid Barajas
10h 35m
PTY6:40 pmPanama City Tocumen Intl
May 6
PTY8:25 pmPanama City Tocumen Intl
9h 50m
MAD1:15 pmMadrid Barajas

Delta flights from Madrid to Panama City

Our best Delta deals on Madrid to Panama City flight tickets
Delta
Apr 24
MAD12:40 pmMadrid Barajas
31h 11m
1 stop
PTY12:51 pmPanama City Tocumen Intl
May 10
PTY2:02 pmPanama City Tocumen Intl
34h 48m
2 stops
MAD7:50 amMadrid Barajas
Delta
Feb 18
MAD10:00 amMadrid Barajas
34h 02m
2 stops
PTY2:02 pmPanama City Tocumen Intl
Mar 10
PTY2:20 pmPanama City Tocumen Intl
34h 40m
2 stops
MAD7:00 amMadrid Barajas
Delta
Mar 11
MAD10:00 amMadrid Barajas
32h 55m
1 stop
PTY12:55 pmPanama City Tocumen Intl
Mar 30
PTY7:24 amPanama City Tocumen Intl
20h 01m
1 stop
MAD10:25 amMadrid Barajas

See travel insights to Panama City from

How to get the cheapest flight ticket from Madrid to Panama City

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Madrid and Panama City?

What is the cheapest month to fly to Panama City?

In general, May is the cheapest month to fly from Madrid to Panama City. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $668. If you’re not able to fly to Panama City in May, then February is your next best option. Flight prices from Madrid to Panama City during February average around $689.

What is the cheapest day to depart on your flight to Panama City?

Our data shows that Friday is the least expensive day to fly to Panama City. Tickets to fly out on this day can be as low as $746. If your travel schedule is flexible, try to avoid departing on a Tuesday because tickets tend to average around $1,060. These prices are subject to change though, so be sure to set up a Price Alert for flights to Panama City.

What is the cheapest time of day to depart on your flight to Panama City?

Our most recent data shows that the best time of day to fly to Panama City is in the morning. Flights from Madrid to Panama City during this time can be as low as $821. Try not to purchase tickets in the afternoon because they tend to be around $905. Of course, these prices can vary depending on the time of year and what airport you fly to.

What is the cheapest Madrid Barajas to Panama City Tocumen Intl flight route?

Fly from Madrid Barajas to Panama City Tocumen Intl for the best Madrid Barajas - Panama City Tocumen Intl flight prices

How far in advance should I book a flight to Panama City?

We recommend purchasing flights from Madrid to Panama City 44 days ahead of your departure date because this is when momondo users tend to see the best flight rates. On average, our users have found flights to Panama City for $795. However, in the past 72 hours, people saw flights from Madrid for as low as $650.

What cabin class options are available on Madrid Barajas to Panama City Tocumen Intl flights?

There are 2 cabin classes available to choose from on Madrid Barajas to Panama City Tocumen Intl flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Madrid to Panama City flights?

You could potentially save up to 3% on your flight if you consider stops on a Madrid to Panama City flight.

How have Madrid to Panama City flight prices changed over time?

As of December 2024, prices for Madrid to Panama City flights are approximately 12% cheaper when compared to flights at the same time last year.

When to book flights from Madrid to Panama City

Are you open to changing your travel dates? Check out the ideal times to fly from Madrid to Panama City according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Madrid to Panama City (MAD to PTY) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Madrid to Panama City

Best Price Found

$420

Fastest flight time

10h 35m

Direct flights

Every day

Airports in Panama City

1 airport
The best one-way flight to Panama City from Madrid in the past 72 hours is $420. The best round-trip flight deal from Madrid to Panama City found on momondo in the last 72 hours is $587.
The fastest flight from Madrid to Panama City takes 10h 35m
Direct flights go from Madrid to Panama City every day.
There is 1 airport near Panama City: Panama City Tocumen Intl (PTY)

  • How far is Madrid Barajas to Panama City Tocumen Intl by plane?

    The straight-line distance from Madrid Barajas to Panama City Tocumen Intl is 5069.0 mi. 10h 35m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Madrid Barajas Airport to Panama City Tocumen Intl Airport?

    Prices for flights from Madrid Barajas Airport to Panama City Tocumen Intl Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Madrid Barajas Airport to Panama City Tocumen Intl Airport?

  • How old do you have to be to fly from Madrid Barajas Airport to Panama City Tocumen Intl Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Madrid Barajas Airport to Panama City Tocumen Intl Airport.

  • What documentation or ID do you need to fly to Panama City Tocumen Intl Airport?

    The travel and health documents required for your trip to Panama City Tocumen Intl Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Panama City Tocumen Intl Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular plane model from Madrid to Panama City?

  • What is the most popular airline from Madrid to Panama City?


Best airlines flying from Madrid to Panama City

Compare and see reviews for airlines that fly from Madrid to Panama City with momondo
Airline
Rating
Free Cancellation
Price
AviancaPriceFrom $582Free CancellationRating
7.0
2,634 reviews
Search Avianca flights
Air EuropaPriceFrom $650Free CancellationRating
7.0
547 reviews
Search Air Europa flights
IberiaPriceFrom $657Free CancellationRating
7.0
2,651 reviews
Search Iberia flights
  • Air Europa Flights From Madrid to Panama City

    Air Europa flies from Madrid to Panama City around 5 times per week, with 547 momondo users rating the airline 7.0/10. The cheapest Air Europa deal from Madrid to Panama City in the last 72 hours was $650 (round-trip), much lower than the average airfare cost of $870 for Air Europa flights on this route.

  • Iberia Flights From Madrid to Panama City

    Another popular option for Madrid to Panama City flights is Iberia (7.0/10, 2,651 ratings). Iberia flies from Madrid to Panama City around 1 time per week, with deals starting from $657 round-trip and rising to an average price of around $821.


Why use momondo?

Why should I use momondo to find a flight deal from Madrid to Panama City?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Madrid to Panama City. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Madrid to Panama City with flexible booking policies on momondo?

All flight searches from Madrid to Panama City on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Madrid to Panama City?

Once you have performed a search for Madrid to Panama City flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Madrid to Panama City right now. Can momondo alert me if prices change?

Price alerts on flights to Panama City from Madrid are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.


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