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Cheap flights from Knoxville to St. Louis from $104

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Knoxville to St. Louis departing on 12/11. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Knoxville to St. Louis

Cheap round-trip flights

These are some of the best round-trip flight deals from Knoxville to St. Louis that have been recently found on momondo from popular airlines, departing in the coming months.

Cheap one-way flights

Flying one-way? These are some of the best deals recently discovered on momondo for flights from Knoxville to St. Louis.

Cheap last minute flights

Planning a quick getaway from Knoxville to St. Louis? These are the last-minute flight deals available now.

Cheap direct flights

If you prefer a non-stop journey, check out our latest direct flight deals to St. Louis, so you can enjoy a seamless trip without layovers.

Cheap bus & train deals from Knoxville to St. Louis

Find recent round-trip train or bus tickets from Knoxville to St. Louis.

All round-trip flight deals to St. Louis

The cheapest plane tickets to St. Louis found on KAYAK recently.
4:19 pm - 9:06 amTYS-STL
17h 47m1 stop
7:09 pm - 3:19 pmSTL-TYS
19h 10m1 stop
$119Frontier
Find Deal
Sun, Jan 12 - Sat, Jan 18
6:30 am - 10:56 amTYS-STL
5h 26m1 stop
9:39 am - 5:21 pmSTL-TYS
6h 42m1 stop
$208American Airlines
Find Deal
Wed, Dec 11 - Sat, Dec 14
9:07 am - 1:25 pmTYS-STL
5h 18m1 stop
5:03 am - 9:59 amSTL-TYS
3h 56m1 stop
$218American Airlines
Find Deal
Wed, Dec 18 - Wed, Dec 25
6:18 pm - 10:25 pmTYS-STL
5h 07m1 stop
2:15 pm - 9:21 pmSTL-TYS
6h 06m1 stop
$230American Airlines
Find Deal
Thu, Mar 13 - Tue, Mar 18
4:04 pm - 8:12 pmTYS-STL
5h 08m1 stop
5:00 pm - 11:51 pmSTL-TYS
5h 51m1 stop
$238Delta
Find Deal
Tue, Dec 3 - Sat, Dec 7
6:57 pm - 11:40 pmTYS-STL
5h 43m1 stop
6:00 am - 10:59 amSTL-TYS
3h 59m1 stop
$323Delta
Find Deal
Sat, Dec 21 - Wed, Dec 25
10:50 am - 3:34 pmTYS-STL
5h 44m1 stop
10:35 am - 4:54 pmSTL-TYS
5h 19m1 stop
$428United Airlines
Find Deal
Thu, Dec 5 - Sun, Dec 22
7:00 am - 12:12 pmTYS-STL
6h 12m1 stop
10:03 am - 11:54 pmSTL-TYS
12h 51m2 stops
$447United Airlines
Find Deal
Thu, Mar 13 - Tue, Mar 18
8:15 am - 3:21 pmTYS-STL
32h 06m3 stops
4:26 pm - 2:07 pmSTL-TYS
20h 41m2 stops
Wed, Dec 11 - Sat, Dec 14
4:44 pm - 3:21 pmTYS-STL
23h 37m2 stops
1:00 pm - 8:20 pmSTL-TYS
30h 20m3 stops
Mon, Dec 30 - Wed, Jan 1
8:02 pm - 11:59 pmTYS-STL
4h 57m1 stop
$104American Airlines
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Wed, Dec 11
10:59 am - 4:21 pmTYS-STL
6h 22m2 stops
$174American Airlines
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Wed, Dec 18
11:00 am - 7:55 pmTYS-STL
33h 55m3 stops
Wed, Jan 15
11:00 am - 12:10 pmTYS-STL
26h 10m3 stops
Wed, Dec 18
11:50 am - 4:38 pmTYS-STL
5h 48m1 stop
$279United Airlines
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Thu, Dec 5
2:30 pm - 10:27 amTYS-STL
20h 57m2 stops
$367United Airlines
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Wed, Dec 11
2:30 pm - 10:34 amTYS-STL
21h 04m2 stops
$469United Airlines
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Thu, Dec 5
4:30 pm - 12:19 pmTYS-STL
20h 49m2 stops
$477United Airlines
Find Deal
Thu, Dec 5
9:09 am - 1:27 pmTYS-STL
5h 18m1 stop
6:34 pm - 11:58 pmSTL-TYS
4h 24m1 stop
$288American Airlines
Find Deal
Fri, Nov 22 - Sun, Nov 24
5:45 am - 3:39 pmTYS-STL
10h 54m2 stops
10:10 am - 4:55 pmSTL-TYS
5h 45m1 stop
$710United Airlines
Find Deal
Fri, Nov 22 - Sun, Nov 24
9:43 pm - 4:26 pmTYS-STL
19h 43m2 stops
5:21 pm - 5:06 pmSTL-TYS
22h 45m2 stops
Fri, Nov 22 - Sun, Nov 24
6:48 pm - 10:10 pmTYS-STL
4h 22m1 stop
10:01 am - 4:08 pmSTL-TYS
5h 07m1 stop
$848American Airlines
Find Deal
Sun, Nov 24 - Mon, Nov 25
10:55 am - 3:39 pmTYS-STL
5h 44m1 stop
7:00 am - 4:55 pmSTL-TYS
8h 55m2 stops
$1,024United Airlines
Find Deal
Sun, Nov 24 - Mon, Nov 25
2:06 pm - 11:28 pmTYS-STL
10h 22m2 stops
12:00 pm - 10:24 pmSTL-TYS
9h 24m2 stops
$1,866United Airlines
Find Deal
Sun, Nov 24 - Mon, Nov 25

American Airlines flights from Knoxville to St. Louis

Our best American Airlines deals on Knoxville to St. Louis flight tickets
American Airlines
Dec 11
TYS6:30 amKnoxville McGhee Tyson
5h 26m
1 stop
STL10:56 amLambert-St Louis
Dec 14
STL9:39 amLambert-St Louis
6h 42m
1 stop
TYS5:21 pmKnoxville McGhee Tyson
American Airlines
Dec 18
TYS9:07 amKnoxville McGhee Tyson
5h 18m
1 stop
STL1:25 pmLambert-St Louis
Dec 25
STL5:03 amLambert-St Louis
3h 56m
1 stop
TYS9:59 amKnoxville McGhee Tyson
American Airlines
Mar 13
TYS6:18 pmKnoxville McGhee Tyson
5h 07m
1 stop
STL10:25 pmLambert-St Louis
Mar 18
STL2:15 pmLambert-St Louis
6h 06m
1 stop
TYS9:21 pmKnoxville McGhee Tyson

United Airlines flights from Knoxville to St. Louis

Our best United Airlines deals on Knoxville to St. Louis flight tickets
United Airlines
Dec 5
TYS10:50 amKnoxville McGhee Tyson
5h 44m
1 stop
STL3:34 pmLambert-St Louis
Dec 22
STL10:35 amLambert-St Louis
5h 19m
1 stop
TYS4:54 pmKnoxville McGhee Tyson
United Airlines
Mar 13
TYS7:00 amKnoxville McGhee Tyson
6h 12m
1 stop
STL12:12 pmLambert-St Louis
Mar 18
STL10:03 amLambert-St Louis
12h 51m
2 stops
TYS11:54 pmKnoxville McGhee Tyson
United Airlines
Dec 11
TYS5:45 amKnoxville McGhee Tyson
10h 49m
2 stops
STL3:34 pmLambert-St Louis
Dec 14
STL8:40 amLambert-St Louis
8h 27m
1 stop
TYS6:07 pmKnoxville McGhee Tyson

How to get the cheapest flight ticket from Knoxville to St. Louis

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly from Knoxville to St. Louis?

April. The cheapest time of year to fly to St. Louis from Knoxville is April. Most expensive is May

What is the cheapest day to depart Knoxville for St. Louis?

Wednesday. The cheapest day of the week is typically Wednesday. The most expensive is typically Sunday

When is the cheapest time to fly from Knoxville to St. Louis?

At noon. Knoxville to St. Louis flights are approximately 7% more expensive in the morning than at noon

What is the cheapest airline that flies to St. Louis from Knoxville?

American Airlines. American Airlines, United Airlines, and Delta are the most popular carriers operating from Knoxville to St. Louis

What is the cheapest Knoxville to St. Louis flight route?

Knoxville McGhee Tyson - Lambert-St Louis. Fly from Knoxville McGhee Tyson to Lambert-St Louis for the best Knoxville - St. Louis flight prices

Can stopping save me money on Knoxville to St. Louis flights?

You could potentially save up to 40% on your flight if you consider stops on a Knoxville to St. Louis flight.

How have Knoxville to St. Louis flight prices changed over time?

As of November 2024, prices for Knoxville to St. Louis flights are approximately 41% more expensive when compared to flights at the same time last year.

When to book flights from Knoxville to St. Louis

Are you open to changing your travel dates? Check out the ideal times to fly from Knoxville to St. Louis according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Knoxville to St. Louis (TYS to STL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to St. Louis

Best Price Found

$104

Fastest flight time

4h 06m

Direct flights

None

Airports in St. Louis

1 airport
The best one-way flight to St. Louis from Knoxville in the past 72 hours is $104. The best round-trip flight deal from Knoxville to St. Louis found on momondo in the last 72 hours is $119.
The fastest flight from Knoxville to St. Louis takes 4h 06m
There are no direct flights from Knoxville to St. Louis. Popular non-direct route for this connection is Knoxville McGhee Tyson Airport - Lambert-St Louis Airport.
There is 1 airport near St. Louis: Lambert-St Louis (STL)

  • How far is Knoxville McGhee Tyson to Lambert-St Louis by plane?

    Lambert-St Louis is 390.7 mi away from Knoxville McGhee Tyson. By plane, this route typically takes 4h 06m.

  • When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Lambert-St Louis Airport?

    Prices for flights from Knoxville McGhee Tyson Airport to Lambert-St Louis Airport are updated daily.

  • How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Lambert-St Louis Airport?

  • How old do you have to be to fly from Knoxville McGhee Tyson Airport to Lambert-St Louis Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to Lambert-St Louis Airport.

  • What documentation or ID do you need to fly to Lambert-St Louis Airport?

    The required travel and health documents for your Lambert-St Louis Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Lambert-St Louis Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Knoxville to St. Louis?


Best airlines flying from Knoxville to St. Louis

Compare and see reviews for airlines that fly from Knoxville to St. Louis with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $212Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights
DeltaPriceFrom $213Free CancellationRating
8.0
8,765 reviews
Search Delta flights
United AirlinesPriceFrom $240Free CancellationRating
7.4
9,173 reviews
Search United Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Knoxville to St. Louis?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Knoxville to St. Louis. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Knoxville to St. Louis with flexible booking policies on momondo?

Yes. All flights to St. Louis from Knoxville on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Knoxville to St. Louis?

momondo provides multiple filters to help you find the best flight to St. Louis from Knoxville. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Knoxville to St. Louis right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Knoxville to St. Louis now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to St. Louis and let you know when they change.


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