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Cheap flights from Knoxville to Santa Ana from $115

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Knoxville to Santa Ana departing on 3/12. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Knoxville to Los Angeles

Cheap round-trip flights

These are some of the best round-trip flight deals from Knoxville to Los Angeles that have been recently found on momondo from popular airlines, departing in the coming months.
5:51 am - 9:33 amTYS-SNA
6h 42m1 stop
7:45 am - 7:32 pmSNA-TYS
8h 47m1 stop
$229American Airlines
Find Deal
mar., mar. 18 - mar., mar. 25
5:51 am - 12:39 pmTYS-SNA
9h 48m2 stops
7:45 am - 7:32 pmSNA-TYS
8h 47m1 stop
$234American Airlines
Find Deal
mar., mar. 18 - mar., mar. 25
2:43 pm - 9:57 amTYS-SNA
22h 14m1 stop
6:45 am - 11:32 amSNA-TYS
25h 47m2 stops
lun., mar. 31 - jue., abr. 3
2:43 pm - 2:38 pmTYS-SNA
26h 55m2 stops
6:45 am - 11:32 amSNA-TYS
25h 47m2 stops
lun., mar. 31 - jue., abr. 3
5:25 pm - 10:25 pmTYS-SNA
8h 00m1 stop
6:45 am - 6:07 pmSNA-TYS
8h 22m1 stop
$319United Airlines
Find Deal
mar., mar. 18 - mar., mar. 25
5:25 pm - 10:25 pmTYS-SNA
8h 00m1 stop
11:00 am - 10:45 pmSNA-TYS
8h 45m2 stops
$324United Airlines
Find Deal
mar., mar. 18 - mar., mar. 25
2:35 pm - 7:47 pmTYS-SNA
8h 12m1 stop
9:30 pm - 9:22 amSNA-TYS
8h 52m1 stop
$339Delta
Find Deal
jue., mar. 20 - lun., mar. 24
5:30 am - 10:31 amTYS-SNA
8h 01m1 stop
2:29 pm - 11:47 pmSNA-TYS
6h 18m1 stop
$434Delta
Find Deal
mié., jun. 11 - mar., jun. 17
12:09 pm - 10:21 pmTYS-SNA
13h 12m2 stops
5:59 pm - 10:40 amSNA-TYS
13h 41m2 stops
$644Alaska Airlines
Find Deal
jue., mar. 6 - lun., mar. 10
12:34 pm - 10:28 pmTYS-SNA
12h 54m2 stops
7:00 am - 9:36 pmSNA-TYS
11h 36m2 stops
$774Alaska Airlines
Find Deal
mar., may. 13 - jue., may. 15

American Airlines flights from Knoxville to Santa Ana

Our best American Airlines deals on Knoxville to Santa Ana flight tickets
American Airlines
Mar 18
TYS5:51 amKnoxville McGhee Tyson
6h 42m
1 stop
SNA9:33 amSanta Ana J. Wayne/Orange Cnty
Mar 25
SNA7:45 amSanta Ana J. Wayne/Orange Cnty
8h 47m
1 stop
TYS7:32 pmKnoxville McGhee Tyson
American Airlines
Mar 18
TYS5:51 amKnoxville McGhee Tyson
9h 48m
2 stops
SNA12:39 pmSanta Ana J. Wayne/Orange Cnty
Mar 25
SNA7:45 amSanta Ana J. Wayne/Orange Cnty
8h 47m
1 stop
TYS7:32 pmKnoxville McGhee Tyson
American Airlines
Mar 12
TYS5:51 amKnoxville McGhee Tyson
7h 27m
1 stop
SNA10:18 amSanta Ana J. Wayne/Orange Cnty
Mar 26
SNA12:37 pmSanta Ana J. Wayne/Orange Cnty
8h 21m
1 stop
TYS11:58 pmKnoxville McGhee Tyson

United Airlines flights from Knoxville to Santa Ana

Our best United Airlines deals on Knoxville to Santa Ana flight tickets
United Airlines
Mar 18
TYS5:25 pmKnoxville McGhee Tyson
8h 00m
1 stop
SNA10:25 pmSanta Ana J. Wayne/Orange Cnty
Mar 25
SNA6:45 amSanta Ana J. Wayne/Orange Cnty
8h 22m
1 stop
TYS6:07 pmKnoxville McGhee Tyson
United Airlines
Mar 18
TYS5:25 pmKnoxville McGhee Tyson
8h 00m
1 stop
SNA10:25 pmSanta Ana J. Wayne/Orange Cnty
Mar 25
SNA11:00 amSanta Ana J. Wayne/Orange Cnty
8h 45m
2 stops
TYS10:45 pmKnoxville McGhee Tyson
United Airlines
Mar 11
TYS4:00 pmKnoxville McGhee Tyson
7h 41m
1 stop
SNA8:41 pmSanta Ana J. Wayne/Orange Cnty
Mar 19
SNA10:58 amSanta Ana J. Wayne/Orange Cnty
8h 47m
1 stop
TYS10:45 pmKnoxville McGhee Tyson

See travel insights to Los Angeles from

How to get the cheapest flight ticket from Knoxville to Santa Ana

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Santa Ana?

The cheapest month to fly to Santa Ana from Knoxville is in February. Flight prices, which tend to average around $313, are often lower during this time because this is during the off-season. The month of August is another great option to travel to Santa Ana, with average flight prices from Knoxville averaging around $352.

What is the cheapest day to depart on your flight to Santa Ana?

On average, the least expensive day to fly to Santa Ana from Knoxville is on a Saturday. momondo users have found tickets for Saturday departures for as low as $406. However, this price may fluctuate depending on the airline, the season, and holidays. On the other hand, Sunday is the most expensive day to depart from Knoxville because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $715.

What is the cheapest time of day to depart on your flight to Santa Ana?

Our data shows that the cheapest Knoxville to Santa Ana flights are usually those with departure times at noon. Our users have found flights to Santa Ana at noon for as low as $388. Try not to purchase tickets in the afternoon because they tend to be around $477. Of course, these prices can vary depending on the time of year and what airport you fly to.

How far in advance should I book a flight to Santa Ana?

You are more likely to see cheaper flights to Santa Ana from Knoxville when booking 26 weeks ahead of your departure date. In general, you can expect to find flights to Santa Ana for around $428 when searching 26 weeks out.However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santa Ana from Knoxville for as low as $291 on momondo.

How have Knoxville to Santa Ana flight prices changed over time?

As of February 2025, prices for Knoxville to Santa Ana flights are approximately 49% more expensive when compared to flights at the same time last year.

When to book flights from Knoxville to Santa Ana

Are you open to changing your travel dates? Check out the ideal times to fly from Knoxville to Santa Ana according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Knoxville to Santa Ana (TYS to SNA) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to Santa Ana

Best Price Found

$115

Fastest flight time

6h 39m

Direct flights

None

Airports in Santa Ana

1 airport
The best one-way flight to Santa Ana from Knoxville in the past 72 hours is $115. The best round-trip flight deal from Knoxville to Santa Ana found on momondo in the last 72 hours is $229.
The fastest flight from Knoxville to Santa Ana takes 6h 39m
There are no direct flights from Knoxville to Santa Ana. Popular non-direct route for this connection is Knoxville McGhee Tyson Airport - Santa Ana J. Wayne/Orange Cnty Airport.
There is 1 airport near Santa Ana: Santa Ana J. Wayne/Orange Cnty (SNA)

  • How far is Knoxville McGhee Tyson to Santa Ana J. Wayne/Orange Cnty by plane?

    Knoxville McGhee Tyson and Santa Ana J. Wayne/Orange Cnty are 1919.8 mi apart from one another. Typically, this will take 6h 42m by plane in normal conditions.

  • When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Santa Ana J. Wayne/Orange Cnty Airport?

    Prices for flights from Knoxville McGhee Tyson Airport to Santa Ana J. Wayne/Orange Cnty Airport are updated daily.

  • How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Santa Ana J. Wayne/Orange Cnty Airport?

  • How old do you have to be to fly from Knoxville McGhee Tyson Airport to Santa Ana J. Wayne/Orange Cnty Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to Santa Ana J. Wayne/Orange Cnty Airport.

  • What documentation or ID do you need to fly to Santa Ana J. Wayne/Orange Cnty Airport?

    The required travel and health documents for your Santa Ana J. Wayne/Orange Cnty Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santa Ana J. Wayne/Orange Cnty Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Knoxville to Santa Ana?


Best airlines flying from Knoxville to Santa Ana

Compare and see reviews for airlines that fly from Knoxville to Santa Ana with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $228Free CancellationRating
7.4
8,766 reviews
Search United Airlines flights
American AirlinesPriceFrom $257Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights
DeltaPriceFrom $287Free CancellationRating
8.0
8,220 reviews
Search Delta flights

Traveling to a place near Los Angeles?

Book flights to Los Angeles if you plan to visit one of these locations
Anaheim
Tustin

Why use momondo?

Why should I use momondo to find a flight deal from Knoxville to Santa Ana?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Knoxville to Santa Ana for you.

Can I find flights from Knoxville to Santa Ana with flexible booking policies on momondo?

Flights from Knoxville to Santa Ana with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Knoxville to Santa Ana?

momondo provides multiple filters to help you find the best flight to Santa Ana from Knoxville. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Knoxville to Santa Ana right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Knoxville to Santa Ana flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.


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