Latest deals
Insights
When to book
FAQs
Reviews
Price Alerts

Cheap flights from Knoxville to Panama City from $222

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Knoxville to Panama City departing on 1/8. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Deals available from 900+ travel sites.

"This year, momondo is the #1 place for airfares on the internet."
Save money when you book flights with momondo
Big names and deals
Big names and deals
Search 100s of travel sites to compare prices.
Filter for what you want
Filter for what you want
Free Wi-Fi? Stopover? Instantly customize your results.
Trusted and free
Trusted and free
We’re completely free to use - no hidden charges or fees.
Price Alerts
Price Alerts
Not ready to book? to track prices.

Find the cheapest flights from Knoxville to Panama City

Cheap round-trip flights

These are some of the best round-trip flight deals from Knoxville to Panama City that have been recently found on momondo from popular airlines, departing in the coming months.

Cheap one-way flights

Flying one-way? These are some of the best deals recently discovered on momondo for flights from Knoxville to Panama City.

Cheap last minute flights

Planning a quick getaway from Knoxville to Panama City? These are the last-minute flight deals available now.

Cheap direct flights

If you prefer a non-stop journey, check out our latest direct flight deals to Panama City, so you can enjoy a seamless trip without layovers.

Cheap bus & train deals from Knoxville to Panama City

Find recent round-trip train or bus tickets from Knoxville to Panama City.

All round-trip flight deals to Panama City

The cheapest plane tickets to Panama City found on KAYAK recently.
6:45 am - 2:45 pmTYS-PTY
8h 00m1 stop
7:55 am - 11:30 pmPTY-TYS
14h 35m1 stop
$456United Airlines
Find Deal
Mon, Jan 20 - Mon, Mar 17
4:55 pm - 5:07 pmTYS-PTY
24h 12m1 stop
7:55 am - 11:30 pmPTY-TYS
14h 35m1 stop
$481United Airlines
Find Deal
Sun, Jan 19 - Mon, Mar 17
8:05 pm - 3:49 pmTYS-PTY
19h 44m2 stops
1:05 pm - 10:54 pmPTY-TYS
8h 49m1 stop
$497American Airlines
Find Deal
Mon, Jan 20 - Tue, Mar 18
6:51 pm - 1:29 pmTYS-PTY
18h 38m2 stops
4:40 pm - 10:36 amPTY-TYS
17h 56m2 stops
$517American Airlines
Find Deal
Thu, Jan 9 - Tue, Jan 21
5:15 pm - 6:34 amTYS-PTY
13h 19m2 stops
12:03 pm - 11:31 pmPTY-TYS
10h 28m1 stop
Sat, Jan 18 - Tue, Mar 18
11:00 am - 8:19 pmTYS-PTY
9h 19m1 stop
12:03 pm - 11:01 amPTY-TYS
21h 58m1 stop
Wed, Jan 22 - Sat, Mar 15
5:45 am - 2:02 pmTYS-PTY
8h 17m1 stop
7:24 am - 11:42 pmPTY-TYS
15h 18m1 stop
$770Delta
Find Deal
Mon, Jan 20 - Sat, Mar 15
5:45 am - 2:02 pmTYS-PTY
8h 17m1 stop
2:20 pm - 9:20 amPTY-TYS
18h 00m1 stop
$777Delta
Find Deal
Mon, Jan 20 - Sun, Mar 16
6:20 am - 1:00 amTYS-PTY
18h 40m2 stops
3:19 am - 10:41 pmPTY-TYS
19h 22m2 stops
$1,030Avianca
Find Deal
Thu, Jan 9 - Mon, Jan 20
6:20 am - 1:00 amTYS-PTY
18h 40m2 stops
3:19 am - 10:41 pmPTY-TYS
19h 22m2 stops
$1,076Avianca
Find Deal
Thu, Jan 9 - Mon, Jan 20
6:20 am - 3:49 pmTYS-PTY
9h 29m1 stop
$222American Airlines
Find Deal
Wed, Jan 8
7:00 am - 5:07 pmTYS-PTY
10h 07m1 stop
8:55 am - 8:00 pmPTY-TYS
11h 05m1 stop
$528United Airlines
Find Deal
Sat, Dec 28 - Tue, Dec 31
7:00 am - 5:07 pmTYS-PTY
10h 07m1 stop
4:40 pm - 8:00 pmPTY-TYS
27h 20m1 stop
$537United Airlines
Find Deal
Sat, Dec 28 - Mon, Dec 30
9:10 am - 7:38 pmTYS-PTY
10h 28m1 stop
8:55 am - 8:00 pmPTY-TYS
11h 05m1 stop
$568United Airlines
Find Deal
Fri, Dec 27 - Tue, Dec 31
9:10 am - 7:38 pmTYS-PTY
10h 28m1 stop
4:40 pm - 8:00 pmPTY-TYS
27h 20m1 stop
$577United Airlines
Find Deal
Fri, Dec 27 - Mon, Dec 30
4:07 pm - 3:20 pmTYS-PTY
23h 13m2 stops
2:40 pm - 12:12 amPTY-TYS
9h 32m1 stop
$713American Airlines
Find Deal
Fri, Dec 27 - Tue, Dec 31
6:26 pm - 1:20 pmTYS-PTY
18h 54m2 stops
2:10 pm - 12:12 amPTY-TYS
10h 02m1 stop
$747American Airlines
Find Deal
Fri, Dec 27 - Mon, Dec 30
5:55 pm - 4:48 pmTYS-PTY
22h 53m2 stops
12:03 pm - 9:26 pmPTY-TYS
9h 23m1 stop
$1,030
Find Deal
Sat, Dec 28 - Tue, Dec 31
9:13 pm - 9:00 pmTYS-PTY
47h 47m3 stops
3:34 pm - 9:16 pmPTY-TYS
29h 42m2 stops
$1,104
Find Deal
Sun, Dec 29 - Fri, Jan 3
6:25 am - 1:55 pmTYS-PTY
7h 30m1 stop
8:10 am - 6:12 pmPTY-TYS
10h 02m1 stop
$1,341Delta
Find Deal
Wed, Dec 25 - Sat, Dec 28
9:50 am - 8:34 pmTYS-PTY
10h 44m1 stop
9:13 am - 7:22 pmPTY-TYS
10h 09m1 stop
$2,289Copa Airlines
Find Deal
Wed, Dec 25 - Mon, Dec 30

American Airlines flights from Knoxville to Panama City

Our best American Airlines deals on Knoxville to Panama City flight tickets
American Airlines
Jan 20
TYS8:05 pmKnoxville McGhee Tyson
19h 44m
2 stops
PTY3:49 pmPanama City Tocumen Intl
Mar 18
PTY1:05 pmPanama City Tocumen Intl
8h 49m
1 stop
TYS10:54 pmKnoxville McGhee Tyson
American Airlines
Jan 9
TYS6:51 pmKnoxville McGhee Tyson
18h 38m
2 stops
PTY1:29 pmPanama City Tocumen Intl
Jan 21
PTY4:40 pmPanama City Tocumen Intl
17h 56m
2 stops
TYS10:36 amKnoxville McGhee Tyson
American Airlines
Jan 9
TYS7:17 pmKnoxville McGhee Tyson
18h 12m
2 stops
PTY1:29 pmPanama City Tocumen Intl
Jan 21
PTY2:35 pmPanama City Tocumen Intl
20h 39m
2 stops
TYS11:14 amKnoxville McGhee Tyson

United Airlines flights from Knoxville to Panama City

Our best United Airlines deals on Knoxville to Panama City flight tickets
United Airlines
Jan 20
TYS6:45 amKnoxville McGhee Tyson
8h 00m
1 stop
PTY2:45 pmPanama City Tocumen Intl
Mar 17
PTY7:55 amPanama City Tocumen Intl
14h 35m
1 stop
TYS11:30 pmKnoxville McGhee Tyson
United Airlines
Jan 19
TYS4:55 pmKnoxville McGhee Tyson
24h 12m
1 stop
PTY5:07 pmPanama City Tocumen Intl
Mar 17
PTY7:55 amPanama City Tocumen Intl
14h 35m
1 stop
TYS11:30 pmKnoxville McGhee Tyson
United Airlines
Jan 9
TYS9:10 amKnoxville McGhee Tyson
7h 57m
1 stop
PTY5:07 pmPanama City Tocumen Intl
Jan 21
PTY11:35 amPanama City Tocumen Intl
12h 11m
1 stop
TYS11:46 pmKnoxville McGhee Tyson

See travel insights to Panama City from

How to get the cheapest flight ticket from Knoxville to Panama City

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Knoxville and Panama City?

What is the cheapest month to fly to Panama City?

In general, March is the cheapest month to fly from Knoxville to Panama City. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $368. If you’re not able to fly to Panama City in March, then February is your next best option. Flight prices from Knoxville to Panama City during February average around $440.

What is the cheapest day to depart on your flight to Panama City?

Our data shows that Friday is the least expensive day to fly to Panama City. Tickets to fly out on this day can be as low as $517. If your travel schedule is flexible, try to avoid departing on a Monday because tickets tend to average around $818. These prices are subject to change though, so be sure to set up a Price Alert for flights to Panama City.

What is the cheapest time of day to depart on your flight to Panama City?

Our most recent data shows that the best time of day to fly to Panama City is in the morning. Flights from Knoxville to Panama City during this time can be as low as $595. Try not to purchase tickets in the morning because they tend to be around $595. Of course, these prices can vary depending on the time of year and what airport you fly to.

When to book flights from Knoxville to Panama City

Are you open to changing your travel dates? Check out the ideal times to fly from Knoxville to Panama City according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Knoxville to Panama City (TYS to PTY) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to Panama City

Best Price Found

$222

Fastest flight time

7h 57m

Direct flights

None

Airports in Panama City

1 airport
The best one-way flight to Panama City from Knoxville in the past 72 hours is $222. The best round-trip flight deal from Knoxville to Panama City found on momondo in the last 72 hours is $456.
The fastest flight from Knoxville to Panama City takes 7h 57m
There are no direct flights from Knoxville to Panama City. Popular non-direct route for this connection is Knoxville McGhee Tyson Airport - Panama City Tocumen Intl Airport.
There is 1 airport near Panama City: Panama City Tocumen Intl (PTY)

  • How far is Knoxville McGhee Tyson to Panama City Tocumen Intl by plane?

    A flight from Knoxville McGhee Tyson to Panama City Tocumen Intl will travel around 1883.0 mi. Typically, this will take 7h 57m by plane in normal conditions.

  • When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Panama City Tocumen Intl Airport?

    Prices for flights from Knoxville McGhee Tyson Airport to Panama City Tocumen Intl Airport were last updated today.

  • How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Panama City Tocumen Intl Airport?

  • How old do you have to be to fly from Knoxville McGhee Tyson Airport to Panama City Tocumen Intl Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to Panama City Tocumen Intl Airport.

  • What documentation or ID do you need to fly to Panama City Tocumen Intl Airport?

    The travel and health documents required for your trip to Panama City Tocumen Intl Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Panama City Tocumen Intl Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular airline from Knoxville to Panama City?


Best airlines flying from Knoxville to Panama City

Compare and see reviews for airlines that fly from Knoxville to Panama City with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $281Free CancellationRating
7.4
9,009 reviews
Search United Airlines flights
American AirlinesPriceFrom $299Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights
DeltaPriceFrom $427Free CancellationRating
8.0
8,580 reviews
Search Delta flights

Why use momondo?

Why should I use momondo to find a flight deal from Knoxville to Panama City?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Knoxville to Panama City. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Knoxville to Panama City with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Panama City from Knoxville with this policy.

How can momondo help me find flights from Knoxville to Panama City?

Once all potential Knoxville to Panama City flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Knoxville to Panama City right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Knoxville to Panama City flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.


An easier way to manage your Panama City trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
From?
To?
Sun 12/29
Sun 1/5
Email me momondo's favorite deals

Find better results for your trip to Panama