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Cheap flights from Knoxville to Des Moines from $157

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Knoxville to Des Moines departing on 5/18. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Knoxville to Des Moines

Cheap round-trip flights

KAYAK's recommended round-trip deals from the most popular airlines that fly from Knoxville to Des Moines.
American Airlines Logo
11:43 am - 3:26 pmTYS-DSM
4h 43m1 stop
American Airlines Logo
7:20 am - 5:21 pmDSM-TYS
9h 01m1 stop
$224American Airlines
Find Deal
sáb., may. 24 - dom., may. 25
American Airlines Logo
7:46 pm - 11:01 pmTYS-DSM
4h 15m1 stop
American Airlines Logo
5:00 am - 12:31 pmDSM-TYS
6h 31m1 stop
$249American Airlines
Find Deal
jue., jul. 24 - mié., jul. 30
United Airlines Logo
4:14 pm - 11:39 pmTYS-DSM
8h 25m1 stop
United Airlines Logo
3:20 pm - 11:46 pmDSM-TYS
7h 26m1 stop
$259United Airlines
Find Deal
jue., may. 1 - lun., may. 5
Delta Logo
11:26 am - 7:15 pmTYS-DSM
8h 49m1 stop
Delta Logo
6:10 am - 12:06 pmDSM-TYS
4h 56m1 stop
$279Delta
Find Deal
vie., jun. 27 - lun., jun. 30
American Airlines Logo
6:51 am - 1:48 pmTYS-DSM
7h 57m2 stops
American Airlines Logo
5:13 am - 11:41 amDSM-TYS
5h 28m1 stop
$318American Airlines
Find Deal
sáb., may. 24 - dom., may. 25
American Airlines Logo
12:44 pm - 7:01 pmTYS-DSM
7h 17m2 stops
American Airlines Logo
5:27 pm - 11:58 pmDSM-TYS
5h 31m1 stop
$374American Airlines
Find Deal
jue., may. 1 - lun., may. 5
United Airlines Logo
7:00 am - 10:29 amTYS-DSM
4h 29m1 stop
United Airlines Logo
3:38 pm - 11:59 pmDSM-TYS
7h 21m2 stops
$415United Airlines
Find Deal
jue., jul. 24 - mié., jul. 30
Delta Logo
7:10 pm - 10:30 pmTYS-DSM
4h 20m1 stop
Delta Logo
5:35 am - 1:38 pmDSM-TYS
7h 03m1 stop
$429Delta
Find Deal
vie., may. 16 - dom., may. 18
United Airlines Logo
10:50 am - 11:54 pmTYS-DSM
14h 04m2 stops
United Airlines Logo
3:35 pm - 11:59 pmDSM-TYS
7h 24m2 stops
$539United Airlines
Find Deal
sáb., may. 24 - dom., may. 25
United Airlines Logo
5:46 pm - 2:44 pmTYS-DSM
21h 58m1 stop
United Airlines Logo
6:24 am - 2:58 pmDSM-TYS
7h 34m2 stops
$548United Airlines
Find Deal
vie., jun. 27 - lun., jun. 30

American Airlines flights from Knoxville to Des Moines

Our best American Airlines deals on Knoxville to Des Moines flight tickets
American Airlines
May 24
TYS11:43 amKnoxville McGhee Tyson
4h 43m
1 stop
DSM3:26 pmDes Moines
May 25
DSM7:20 amDes Moines
9h 01m
1 stop
TYS5:21 pmKnoxville McGhee Tyson
American Airlines
Jul 24
TYS7:46 pmKnoxville McGhee Tyson
4h 15m
1 stop
DSM11:01 pmDes Moines
Jul 30
DSM5:00 amDes Moines
6h 31m
1 stop
TYS12:31 pmKnoxville McGhee Tyson
American Airlines
May 24
TYS6:51 amKnoxville McGhee Tyson
7h 57m
2 stops
DSM1:48 pmDes Moines
May 25
DSM5:13 amDes Moines
5h 28m
1 stop
TYS11:41 amKnoxville McGhee Tyson

United Airlines flights from Knoxville to Des Moines

Our best United Airlines deals on Knoxville to Des Moines flight tickets
United Airlines
May 1
TYS4:14 pmKnoxville McGhee Tyson
8h 25m
1 stop
DSM11:39 pmDes Moines
May 5
DSM3:20 pmDes Moines
7h 26m
1 stop
TYS11:46 pmKnoxville McGhee Tyson
United Airlines
Jul 24
TYS7:00 amKnoxville McGhee Tyson
4h 29m
1 stop
DSM10:29 amDes Moines
Jul 30
DSM3:38 pmDes Moines
7h 21m
2 stops
TYS11:59 pmKnoxville McGhee Tyson
United Airlines
May 24
TYS10:50 amKnoxville McGhee Tyson
14h 04m
2 stops
DSM11:54 pmDes Moines
May 25
DSM3:35 pmDes Moines
7h 24m
2 stops
TYS11:59 pmKnoxville McGhee Tyson

See travel insights to Des Moines from

How to get the cheapest flight ticket from Knoxville to Des Moines

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Des Moines?

If you’re not able to fly to Des Moines in August, then February is your next best option. Flight prices from Knoxville to Des Moines during February average around $278.

What is the cheapest day to depart on your flight to Des Moines?

The cheapest day to depart from Knoxville to Des Moines is on a Thursday. Travelers who choose to depart for Des Moines on a Thursday will often find tickets for as low as $262. Flights from Knoxville to Des Moines on a Monday will generally be more expensive and average around $581. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

What is the cheapest time of day to depart on your flight to Des Moines?

According to our data, the cheapest time of day to fly to Des Moines is in the morning. momondo users have found flights departing from Knoxville to Des Moines in the morning for as low as $320. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Try not to purchase tickets in the evening because they tend to be around $338. Of course, these prices can vary depending on the time of year and what airport you fly to.

When to book flights from Knoxville to Des Moines

Are you open to changing your travel dates? Check out the ideal times to fly from Knoxville to Des Moines according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Knoxville to Des Moines (TYS to DSM) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to Des Moines

Best Price Found

$157

Fastest flight time

4h 15m

Direct flights

None

Airports in Des Moines

1 airport
The best one-way flight to Des Moines from Knoxville in the past 72 hours is $157. The best round-trip flight deal from Knoxville to Des Moines found on momondo in the last 72 hours is $224.
The fastest flight from Knoxville to Des Moines takes 4h 15m
There are no direct flights from Knoxville to Des Moines. Popular non-direct route for this connection is Knoxville McGhee Tyson Airport - Des Moines Airport.
There is 1 airport near Des Moines: Des Moines (DSM)

  • How far is Knoxville McGhee Tyson to Des Moines by plane?

    There are 650.4 mi between Knoxville McGhee Tyson and Des Moines. A reasonable flight in good conditions will take 4h 15m.

  • When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Des Moines Airport?

    Prices for flights from Knoxville McGhee Tyson Airport to Des Moines Airport were last updated today.

  • How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Des Moines Airport?

  • How old do you have to be to fly from Knoxville McGhee Tyson Airport to Des Moines Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Knoxville McGhee Tyson Airport to Des Moines Airport.

  • What documentation or ID do you need to fly to Des Moines Airport?

    The necessary travel and health documents for your Des Moines Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Knoxville to Des Moines?


Best airlines flying from Knoxville to Des Moines

Compare and see reviews for airlines that fly from Knoxville to Des Moines with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $212Free CancellationRating
8.0
7,917 reviews
Search Delta flights
American AirlinesPriceFrom $248Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights
United AirlinesPriceFrom $252Free CancellationRating
7.4
8,667 reviews
Search United Airlines flights

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
West Des Moines
Ames
Ankeny
Clive
Altoona
Newton
Pella
Urbandale
Osceola
Boone
Johnston
Norwalk
Oskaloosa
Grinnell

Why use momondo?

Why should I use momondo to find a flight deal from Knoxville to Des Moines?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Knoxville to Des Moines. momondo saves you time and could save you money on your trip.

Can I find flights from Knoxville to Des Moines with flexible booking policies on momondo?

Flights from Knoxville to Des Moines with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Knoxville to Des Moines?

Once all potential Knoxville to Des Moines flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Knoxville to Des Moines right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Des Moines, momondo offers a useful price alert feature which will track prices for flights to Des Moines from Knoxville and alert you when they change.


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mar. 4/22
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