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Cheap flights from Knoxville to Des Moines from $283

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Knoxville to Des Moines departing on 1/3. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Knoxville to Des Moines

Cheap round-trip flights

These are some of the best round-trip flight deals from Knoxville to Des Moines that have been recently found on momondo from popular airlines, departing in the coming months.

Cheap one-way flights

Flying one-way? These are some of the best deals recently discovered on momondo for flights from Knoxville to Des Moines.

Cheap last minute flights

Planning a quick getaway from Knoxville to Des Moines? These are the last-minute flight deals available now.

Cheap direct flights

If you prefer a non-stop journey, check out our latest direct flight deals to Des Moines, so you can enjoy a seamless trip without layovers.

Cheap bus & train deals from Knoxville to Des Moines

Find recent round-trip train or bus tickets from Knoxville to Des Moines.

All round-trip flight deals to Des Moines

The cheapest plane tickets to Des Moines found on KAYAK recently.
5:53 am - 11:48 amTYS-DSM
6h 55m1 stop
5:45 am - 11:09 amDSM-TYS
4h 24m1 stop
$283American Airlines
Find Deal
Fri, Jan 3 - Sun, Jan 5
6:21 pm - 10:51 pmTYS-DSM
5h 30m1 stop
5:29 pm - 11:58 pmDSM-TYS
5h 29m1 stop
$369American Airlines
Find Deal
Thu, Mar 13 - Sun, Mar 16
4:55 pm - 10:30 pmTYS-DSM
6h 35m1 stop
11:35 am - 1:18 pmDSM-TYS
24h 43m1 stop
$418United Airlines
Find Deal
Mon, Jan 6 - Fri, Jan 10
8:15 am - 2:00 pmTYS-DSM
6h 45m1 stop
2:41 pm - 4:25 pmDSM-TYS
24h 44m2 stops
Mon, Jan 6 - Fri, Jan 10
8:15 am - 2:00 pmTYS-DSM
6h 45m1 stop
2:41 pm - 4:25 pmDSM-TYS
24h 44m3 stops
Mon, Jan 6 - Fri, Jan 10
5:53 am - 11:48 amTYS-DSM
6h 55m1 stop
5:45 am - 3:37 pmDSM-TYS
8h 52m2 stops
$426American Airlines
Find Deal
Fri, Jan 3 - Sun, Jan 5
5:40 am - 9:38 pmTYS-DSM
16h 58m2 stops
6:45 pm - 10:45 pmDSM-TYS
27h 00m1 stop
$507United Airlines
Find Deal
Thu, Mar 13 - Sun, Mar 16
5:40 am - 9:38 pmTYS-DSM
16h 58m2 stops
6:45 pm - 3:04 pmDSM-TYS
19h 19m2 stops
$631United Airlines
Find Deal
Thu, Mar 13 - Sun, Mar 16
7:24 pm - 2:28 pmTYS-DSM
20h 04m2 stops
6:40 pm - 6:05 pmDSM-TYS
22h 25m2 stops
$682United Airlines
Find Deal
Fri, Jan 3 - Sun, Jan 5
TYS-DSM
654 mimulti-stop
Multiple Airlines
Find Deal
6:10 pm - 11:07 pmTYS-DSM
5h 57m1 stop
5:39 pm - 12:20 amDSM-TYS
5h 41m1 stop
$603American Airlines
Find Deal
Wed, Dec 25 - Fri, Dec 27
7:05 am - 3:08 pmTYS-DSM
9h 03m2 stops
5:39 pm - 12:20 amDSM-TYS
5h 41m1 stop
$608American Airlines
Find Deal
Wed, Dec 25 - Fri, Dec 27
9:08 am - 3:08 pmTYS-DSM
7h 00m2 stops
12:47 pm - 9:30 pmDSM-TYS
7h 43m2 stops
$693American Airlines
Find Deal
Wed, Dec 25 - Fri, Dec 27

American Airlines flights from Knoxville to Des Moines

Our best American Airlines deals on Knoxville to Des Moines flight tickets
American Airlines
Jan 3
TYS5:53 amKnoxville McGhee Tyson
6h 55m
1 stop
DSM11:48 amDes Moines
Jan 5
DSM5:45 amDes Moines
4h 24m
1 stop
TYS11:09 amKnoxville McGhee Tyson
American Airlines
Mar 13
TYS6:21 pmKnoxville McGhee Tyson
5h 30m
1 stop
DSM10:51 pmDes Moines
Mar 16
DSM5:29 pmDes Moines
5h 29m
1 stop
TYS11:58 pmKnoxville McGhee Tyson
American Airlines
Jan 3
TYS5:53 amKnoxville McGhee Tyson
6h 55m
1 stop
DSM11:48 amDes Moines
Jan 5
DSM5:45 amDes Moines
8h 52m
2 stops
TYS3:37 pmKnoxville McGhee Tyson

United Airlines flights from Knoxville to Des Moines

Our best United Airlines deals on Knoxville to Des Moines flight tickets
United Airlines
Jan 6
TYS4:55 pmKnoxville McGhee Tyson
6h 35m
1 stop
DSM10:30 pmDes Moines
Jan 10
DSM11:35 amDes Moines
24h 43m
1 stop
TYS1:18 pmKnoxville McGhee Tyson
United Airlines
Mar 13
TYS5:40 amKnoxville McGhee Tyson
16h 58m
2 stops
DSM9:38 pmDes Moines
Mar 16
DSM6:45 pmDes Moines
27h 00m
1 stop
TYS10:45 pmKnoxville McGhee Tyson
United Airlines
Mar 13
TYS5:40 amKnoxville McGhee Tyson
16h 58m
2 stops
DSM9:38 pmDes Moines
Mar 16
DSM6:45 pmDes Moines
19h 19m
2 stops
TYS3:04 pmKnoxville McGhee Tyson

See travel insights to Des Moines from

How to get the cheapest flight ticket from Knoxville to Des Moines

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Des Moines?

If you’re not able to fly to Des Moines in August, then March is your next best option. Flight prices from Knoxville to Des Moines during March average around $282.

What is the cheapest day to depart on your flight to Des Moines?

The cheapest day to depart from Knoxville to Des Moines is on a Thursday. Travelers who choose to depart for Des Moines on a Thursday will often find tickets for as low as $262. Flights from Knoxville to Des Moines on a Monday will generally be more expensive and average around $581. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

What is the cheapest time of day to depart on your flight to Des Moines?

According to our data, the cheapest time of day to fly to Des Moines is in the morning. momondo users have found flights departing from Knoxville to Des Moines in the morning for as low as $320. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Try not to purchase tickets in the evening because they tend to be around $338. Of course, these prices can vary depending on the time of year and what airport you fly to.

When to book flights from Knoxville to Des Moines

Are you open to changing your travel dates? Check out the ideal times to fly from Knoxville to Des Moines according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Knoxville to Des Moines (TYS to DSM) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to Des Moines

Best Price Found

$283

Fastest flight time

5h 30m

Direct flights

None

Airports in Des Moines

1 airport
The best flight deal from Knoxville to Des Moines found on momondo in the last 72 hours is $283
The fastest flight from Knoxville to Des Moines takes 5h 30m
There are no direct flights from Knoxville to Des Moines. Popular non-direct route for this connection is Knoxville McGhee Tyson Airport - Des Moines Airport.
There is 1 airport near Des Moines: Des Moines (DSM)

  • How far is Knoxville McGhee Tyson to Des Moines by plane?

    There are 650.4 mi between Knoxville McGhee Tyson and Des Moines. A reasonable flight in good conditions will take 5h 30m.

  • When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Des Moines Airport?

    Prices for flights from Knoxville McGhee Tyson Airport to Des Moines Airport were last updated today.

  • How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Des Moines Airport?

  • How old do you have to be to fly from Knoxville McGhee Tyson Airport to Des Moines Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Knoxville McGhee Tyson Airport to Des Moines Airport.

  • What documentation or ID do you need to fly to Des Moines Airport?

    The necessary travel and health documents for your Des Moines Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Knoxville to Des Moines?


Best airlines flying from Knoxville to Des Moines

Compare and see reviews for airlines that fly from Knoxville to Des Moines with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $212Free CancellationRating
8.0
8,588 reviews
Search Delta flights
American AirlinesPriceFrom $248Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights
United AirlinesPriceFrom $252Free CancellationRating
7.4
9,020 reviews
Search United Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Knoxville to Des Moines?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Knoxville to Des Moines. momondo saves you time and could save you money on your trip.

Can I find flights from Knoxville to Des Moines with flexible booking policies on momondo?

Flights from Knoxville to Des Moines with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Knoxville to Des Moines?

Once all potential Knoxville to Des Moines flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Knoxville to Des Moines right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Des Moines, momondo offers a useful price alert feature which will track prices for flights to Des Moines from Knoxville and alert you when they change.


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