What is the cheapest airline that flies from Iowa to South Carolina?

Southwest, Delta, and American Airlines are the most popular carriers operating from Iowa to South Carolina

How many flights depart from Iowa to South Carolina on average per week?

56 flights are operational weekly from Iowa to South Carolina as of April 2025. The most popular departure day for this route is Mon, with 14% of flights per week taking off on this day.

How long is the flight from Iowa to South Carolina?

Flight times vary depending on what airport in Iowa you fly out of and what airport in South Carolina you fly into. For example, flying from Des Moines to Charleston takes 4h 09m on average. On the other hand, flying from Cedar Rapids to Charleston takes 4h 57m on average. Keep in mind that it’s always quicker to opt for a non-stop flight, so be sure to check momondo if there are any available for your route.

What airlines fly to South Carolina?

American Airlines, Delta and United Airlines are the top three most popular airlines that fly to South Carolina from Iowa according to our data. American Airlines is the first choice among our users, with 71% of people opting to fly with this airline when traveling to South Carolina. Keep in mind that there are 4 different airlines that fly to South Carolina on a routine basis, so you have a few additional options to choose from.

When did momondo last update prices for flights from Iowa to South Carolina?

Prices for flights from Iowa to South Carolina are updated daily.

How many operators does momondo search for flights from Iowa to South Carolina?

As of April 2025, there are 4 operators available to choose from for flights from Iowa to South Carolina.

How old do you have to be to fly from Iowa to South Carolina?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Iowa to South Carolina.

What documentation or ID do you need to fly to South Carolina?

The travel and health documents required for your trip to South Carolina can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at South Carolina. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

$105 Cheap Flights from Iowa to South Carolina in 2025

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Find the cheapest flights from Iowa to South Carolina

Round-trip

One-way

Last minute

Direct

Cheap round-trip flights

KAYAK's recommended round-trip deals from the most popular airlines that fly from Iowa to South Carolina.

7:15 am - 12:20 pmCID-SAV

4h 05m1 stop

7:56 pm - 11:45 pmSAV-CID

4h 49m1 stop

$199American Airlines

Find Deal

mar., jul. 1 - sáb., jul. 5

11:30 am - 10:04 pmCID-CHS

9h 34m2 stops

6:25 am - 11:47 amCHS-CID

6h 22m1 stop

$204American Airlines

Find Deal

sáb., may. 24 - sáb., may. 31

6:25 am - 2:16 pmCID-CHS

6h 51m1 stop

6:24 pm - 11:00 pmCHS-CID

5h 36m1 stop

$237Delta

Find Deal

dom., may. 25 - vie., may. 30

12:32 pm - 3:37 pmDSM-CLT

26h 05m1 stop

9:45 pm - 11:27 pmCLT-DSM

26h 42m2 stops

$237

Find Deal

dom., may. 18 - mié., may. 21

5:30 am - 1:33 pmCID-CHS

7h 03m1 stop

5:35 am - 11:17 amCHS-CID

6h 42m2 stops

$242Delta

Find Deal

dom., may. 25 - jue., may. 29

5:19 pm - 3:51 pmDSM-CLT

21h 32m2 stops

5:33 pm - 9:24 pmCLT-DSM

4h 51m1 stop

$244

Find Deal

vie., jun. 6 - vie., jun. 13

8:35 am - 1:15 pmDSM-CLT

3h 40m1 stop

6:10 pm - 11:50 pmCLT-DSM

6h 40m1 stop

$251Southwest

Find Deal

vie., jul. 4 - lun., jul. 7

7:00 am - 12:30 pmOMA-CLT

4h 30m1 stop

5:05 pm - 10:25 pmCLT-OMA

6h 20m1 stop

$306Southwest

Find Deal

jue., sep. 11 - lun., sep. 15

6:37 am - 2:34 pmCID-SAV

6h 57m1 stop

4:45 pm - 9:26 pmSAV-CID

5h 41m1 stop

$319United Airlines

Find Deal

vie., jul. 18 - mar., jul. 22

8:05 am - 2:02 pmCID-CHS

4h 57m1 stop

9:50 am - 7:08 pmCHS-CID

10h 18m2 stops

$324United Airlines

Find Deal

lun., may. 26 - sáb., may. 31

Southwest flights from Iowa to South Carolina

Our best Southwest deals on Iowa to South Carolina flight tickets

Southwest

Jul 4

DSM8:35 amDes Moines

3h 40m

1 stop

CLT1:15 pmCharlotte Douglas

Jul 7

CLT6:10 pmCharlotte Douglas

6h 40m

1 stop

DSM11:50 pmDes Moines

$251

Find similar

Southwest

Sep 11

OMA7:00 amOmaha Eppley Airfield

4h 30m

1 stop

CLT12:30 pmCharlotte Douglas

Sep 15

CLT5:05 pmCharlotte Douglas

6h 20m

1 stop

OMA10:25 pmOmaha Eppley Airfield

$306

Find similar

Southwest

Sep 11

OMA7:00 amOmaha Eppley Airfield

4h 30m

1 stop

CLT12:30 pmCharlotte Douglas

Sep 15

CLT10:40 amCharlotte Douglas

8h 00m

2 stops

OMA5:40 pmOmaha Eppley Airfield

$311

Find similar

American Airlines flights from Iowa to South Carolina

Our best American Airlines deals on Iowa to South Carolina flight tickets

American Airlines

Jul 1

CID7:15 amCedar Rapids

4h 05m

1 stop

SAV12:20 pmSavannah/Hilton Head

Jul 5

SAV7:56 pmSavannah/Hilton Head

4h 49m

1 stop

CID11:45 pmCedar Rapids

$199

Find similar

American Airlines

May 24

CID11:30 amCedar Rapids

9h 34m

2 stops

CHS10:04 pmCharleston

May 31

CHS6:25 amCharleston

6h 22m

1 stop

CID11:47 amCedar Rapids

$204

Find similar

American Airlines

May 24

CID11:30 amCedar Rapids

7h 28m

2 stops

CHS7:58 pmCharleston

May 31

CHS3:31 pmCharleston

9h 13m

2 stops

CID11:44 pmCedar Rapids

$209

Find similar

How to get the cheapest flight ticket from Iowa to South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the cheapest month to fly to South Carolina?

The cheapest month to fly to South Carolina from Iowa is in September. Flight prices, which tend to average around $344, are often lower during this time because this is during the off-season. If you aren’t able to travel during the month of September, then book flights to South Carolina from Iowa during August instead. Flights to South Carolina in August, while not as cheap as those in September, still average around $358.

What is the cheapest day to depart on your flight to South Carolina?

Our data shows that Monday is the least expensive day to fly to South Carolina. Tickets to fly out on this day can be as low as $379. The most expensive day to fly to South Carolina is Thursday, with ticket prices averaging around $508.

What is the cheapest time of day to depart on your flight to South Carolina?

Our data shows that the cheapest Iowa to South Carolina flights are usually those with departure times in the afternoon. Our users have found flights to South Carolina in the afternoon for as low as $386. Try not to purchase tickets in the morning because they tend to be around $405. Of course, these prices can vary depending on the time of year and what airport you fly to.

How far in advance should I book a flight to South Carolina?

You are more likely to see cheaper flights to South Carolina from Iowa when booking 10 weeks ahead of your departure date. In general, you can expect to find flights to South Carolina for around $400 when searching 10 weeks out.However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South Carolina from Iowa for as low as $319 on momondo.

Cheap Iowa to South Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Iowa to South Carolina

Best Price Found	$105
Fastest flight time	2h 08m
Direct flights	Every day
Airports in South Carolina	4 airports

The best one-way flight to South Carolina from Iowa in the past 72 hours is $105. The best round-trip flight deal from Iowa to South Carolina found on momondo in the last 72 hours is $199.

The fastest flight from Iowa to South Carolina takes 2h 08m

Direct flights go from Iowa to South Carolina every day.

There are 4 airports near South Carolina: Myrtle Beach Intl (MYR), Savannah/Hilton Head (SAV), Charlotte Douglas (CLT), Charleston (CHS)

Search flight deals

When did momondo last update prices for flights from Iowa to South Carolina?
Prices for flights from Iowa to South Carolina are updated daily.
How many operators does momondo search for flights from Iowa to South Carolina?
As of April 2025, there are 4 operators available to choose from for flights from Iowa to South Carolina.
How old do you have to be to fly from Iowa to South Carolina?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Iowa to South Carolina.
What documentation or ID do you need to fly to South Carolina?
The travel and health documents required for your trip to South Carolina can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at South Carolina. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Best airlines flying from Iowa to South Carolina

Compare and see reviews for airlines that fly from Iowa to South Carolina with momondo

Airline	Rating	Free Cancellation	Price
American Airlines	PriceFrom $198	Free Cancellation	Rating 7.2 10,000 reviews	Search American Airlines flights
United Airlines	PriceFrom $227	Free Cancellation	Rating 7.4 8,685 reviews	Search United Airlines flights
Delta	PriceFrom $232	Free Cancellation	Rating 8.0 7,920 reviews	Search Delta flights
Southwest	PriceFrom $376	Free Cancellation	Rating 8.0 4,287 reviews	Search Southwest flights

Why use momondo?

Why should I use momondo to find a flight deal from Iowa to South Carolina?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Iowa to South Carolina. momondo saves you time and could save you money on your trip.

Can I find flights from Iowa to South Carolina with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Iowa to South Carolina flights to just show those with flexible booking policies.

How can momondo help me find flights from Iowa to South Carolina?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to South Carolina from Iowa.

I’m not ready to book a flight from Iowa to South Carolina right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Iowa to South Carolina flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.