What airlines fly to Des Moines?

American Airlines, Delta and United Airlines are the top three most popular airlines that fly to Des Moines from Greenville according to our data. American Airlines is the first choice among our users, with 77% of people opting to fly with this airline when traveling to Des Moines. Keep in mind that there are 4 different airlines that fly to Des Moines on a routine basis, so you have a few additional options to choose from.

What is the cheapest airline that flies from Greenville to Des Moines?

American Airlines is the most popular carrier operating from Greenville to Des Moines

When did momondo last update prices for flights from Greenville Airport to Des Moines Airport?

Prices for flights from Greenville Airport to Des Moines Airport were last updated today.

How many operators does momondo search for flights from Greenville Airport to Des Moines Airport?

The number of operators available for flights from Greenville Airport to Des Moines Airport is 2 as of January 2025.

How old do you have to be to fly from Greenville Airport to Des Moines Airport?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Greenville Airport to Des Moines Airport.

What documentation or ID do you need to fly to Des Moines Airport?

The necessary travel and health documents for your Des Moines Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

$149 Cheap Flights from Greenville to Des Moines in 2025

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Find the cheapest flights from Greenville to Des Moines

Round-tripOne-way

Cheap round-trip flights

These are some of the best round-trip flight deals from Greenville to Des Moines that have been recently found on momondo from popular airlines, departing in the coming months.

Cheap one-way flights

Flying one-way? These are some of the best deals recently discovered on momondo for flights from Greenville to Des Moines.

Cheap last minute flights

Planning a quick getaway from Greenville to Des Moines? These are the last-minute flight deals available now.

Cheap direct flights

If you prefer a non-stop journey, check out our latest direct flight deals to Des Moines, so you can enjoy a seamless trip without layovers.

Cheap bus & train deals from Greenville to Des Moines

Find recent round-trip train or bus tickets from Greenville to Des Moines.

All round-trip flight deals from Greenville to Des Moines

The cheapest plane tickets from Greenville to Des Moines found on KAYAK recently.

6:30 am - 10:37 amGSP-DSM

5h 07m1 stop

8:00 am - 7:05 pmDSM-GSP

10h 05m2 stops

$337United Airlines

Find Deal

Sat, Feb 15 - Fri, Feb 21

5:40 am - 10:40 amGSP-DSM

6h 00m1 stop

4:20 pm - 11:46 pmDSM-GSP

6h 26m1 stop

$342Delta

Find Deal

Wed, Feb 12 - Sat, Feb 15

5:25 pm - 8:57 pmGSP-DSM

4h 32m1 stop

4:20 pm - 11:49 pmDSM-GSP

6h 29m1 stop

$347Delta

Find Deal

Wed, Feb 12 - Sun, Feb 16

7:14 am - 10:40 amGSP-DSM

4h 26m1 stop

6:26 pm - 11:49 pmDSM-GSP

4h 23m1 stop

$367Delta

Find Deal

Fri, Feb 14 - Mon, Feb 17

2:55 pm - 9:52 pmGSP-DSM

7h 57m2 stops

8:00 am - 2:00 pmDSM-GSP

5h 00m1 stop

$372United Airlines

Find Deal

Wed, Feb 12 - Sat, Feb 15

6:22 am - 5:54 pmGSP-DSM

12h 32m2 stops

8:00 am - 7:05 pmDSM-GSP

10h 05m2 stops

$377United Airlines

Find Deal

Wed, Feb 12 - Sat, Feb 15

8:10 am - 2:46 pmGSP-DSM

7h 36m2 stops

5:50 am - 11:51 amDSM-GSP

5h 01m1 stop

$382American Airlines

Find Deal

Thu, Feb 13 - Sun, Feb 16

7:10 am - 12:21 pmGSP-DSM

6h 11m1 stop

4:00 pm - 11:41 pmDSM-GSP

6h 41m2 stops

$402American Airlines

Find Deal

Fri, Feb 14 - Sun, Feb 16

10:45 am - 11:35 pmGSP-DSM

13h 50m2 stops

5:30 am - 9:40 pmDSM-GSP

15h 10m2 stops

$457Southwest

Find Deal

Fri, Feb 14 - Mon, Feb 17

12:10 pm - 10:10 pmGSP-DSM

11h 00m2 stops

5:30 am - 9:40 pmDSM-GSP

15h 10m2 stops

$467Southwest

Find Deal

Thu, Feb 13 - Sun, Feb 16

7:45 am - 1:36 pmGSP-DSM

6h 51m1 stop

$149American Airlines

Find Deal

Sat, Feb 1

5:21 am - 12:11 pmGSP-DSM

7h 50m2 stops

$154American Airlines

Find Deal

Sat, Feb 1

Southwest flights from Greenville to Des Moines

Our best Southwest deals on Greenville to Des Moines flight tickets

Southwest

Feb 14

GSP10:45 amGreenville

13h 50m

2 stops

DSM11:35 pmDes Moines

Feb 17

DSM5:30 amDes Moines

15h 10m

2 stops

GSP9:40 pmGreenville

$457

Find similar

Southwest

Feb 13

GSP12:10 pmGreenville

11h 00m

2 stops

DSM10:10 pmDes Moines

Feb 16

DSM5:30 amDes Moines

15h 10m

2 stops

GSP9:40 pmGreenville

$467

Find similar

American Airlines flights from Greenville to Des Moines

Our best American Airlines deals on Greenville to Des Moines flight tickets

American Airlines

Feb 13

GSP8:10 amGreenville

7h 36m

2 stops

DSM2:46 pmDes Moines

Feb 16

DSM5:50 amDes Moines

5h 01m

1 stop

GSP11:51 amGreenville

$382

Find similar

American Airlines

Feb 14

GSP7:10 amGreenville

6h 11m

1 stop

DSM12:21 pmDes Moines

Feb 16

DSM4:00 pmDes Moines

6h 41m

2 stops

GSP11:41 pmGreenville

$402

Find similar

American Airlines

Mar 20

GSP8:00 amGreenville

7h 22m

1 stop

DSM2:22 pmDes Moines

Mar 25

DSM2:07 pmDes Moines

4h 00m

1 stop

GSP7:07 pmGreenville

$461

Find similar

How to get the cheapest flight ticket from Greenville to Des Moines

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to Des Moines?

If you’re not able to fly to Des Moines in September, then July is your next best option. Flight prices from Greenville to Des Moines during July average around $336.

What is the cheapest day to depart on your flight to Des Moines?

The cheapest day to depart from Greenville to Des Moines is on a Saturday. Travelers who choose to depart for Des Moines on a Saturday will often find tickets for as low as $327. Flights from Greenville to Des Moines on a Monday will generally be more expensive and average around $673. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

What is the cheapest time of day to depart on your flight to Des Moines?

According to our data, the cheapest time of day to fly to Des Moines is at noon. momondo users have found flights departing from Greenville to Des Moines at noon for as low as $336. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Try not to purchase tickets in the evening because they tend to be around $543. Of course, these prices can vary depending on the time of year and what airport you fly to.

When to book flights from Greenville to Des Moines

Are you open to changing your travel dates? Check out the ideal times to fly from Greenville to Des Moines according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Greenville to Des Moines (GSP to DSM) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Greenville to Des Moines

Best Price Found	$149
Fastest flight time	4h 26m
Direct flights	None
Airports in Des Moines	1 airport

The best one-way flight to Des Moines from Greenville in the past 72 hours is $149. The best round-trip flight deal from Greenville to Des Moines found on momondo in the last 72 hours is $337.

The fastest flight from Greenville to Des Moines takes 4h 26m

There are no direct flights from Greenville to Des Moines. Popular non-direct route for this connection is Greenville Airport - Des Moines Airport.

There is 1 airport near Des Moines: Des Moines (DSM)

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How far is Greenville to Des Moines by plane?
Des Moines is 765.4 mi away from Greenville. In terms of flight time, this usually takes a little over 4h 26m.
When did momondo last update prices for flights from Greenville Airport to Des Moines Airport?
Prices for flights from Greenville Airport to Des Moines Airport were last updated today.
How many operators does momondo search for flights from Greenville Airport to Des Moines Airport?
The number of operators available for flights from Greenville Airport to Des Moines Airport is 2 as of January 2025.
How old do you have to be to fly from Greenville Airport to Des Moines Airport?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Greenville Airport to Des Moines Airport.
What documentation or ID do you need to fly to Des Moines Airport?
The necessary travel and health documents for your Des Moines Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.
What is the most popular airline from Greenville to Des Moines?
Based on momondo bookings for this flight route, the most popular airline on flight routes from Greenville to Des Moines is American Airlines (59% of total bookings). The next most popular airline is Delta (41%).

Best airlines flying from Greenville to Des Moines

Compare and see reviews for airlines that fly from Greenville to Des Moines with momondo

Airline	Rating	Free Cancellation	Price
American Airlines	PriceFrom $286	Free Cancellation	Rating 7.2 10,000 reviews		Search American Airlines flights
Delta	PriceFrom $315	Free Cancellation	Rating 8.0 8,511 reviews		Search Delta flights

West Des Moines

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Boone

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Why use momondo?

Why should I use momondo to find a flight deal from Greenville to Des Moines?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Greenville to Des Moines. momondo saves you time and could save you money on your trip.

Can I find flights from Greenville to Des Moines with flexible booking policies on momondo?

Yes. All flights to Des Moines from Greenville on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Greenville to Des Moines?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Des Moines from Greenville.

I’m not ready to book a flight from Greenville to Des Moines right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Greenville to Des Moines now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Des Moines and let you know when they change.