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Cheap flights from Detroit to Greenville from $108

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Detroit to Greenville departing on 5/18. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Detroit to Greenville

Cheap round-trip flights

KAYAK's recommended round-trip deals from the most popular airlines that fly from Detroit to Greenville.
 Logo
6:38 am - 2:16 pmDTW-GSP
31h 38m2 stops
 Logo
10:01 pm - 8:13 pmGSP-DTW
22h 12m2 stops
Thu, May 15 - Sun, May 18
 Logo
5:18 pm - 8:20 amDTW-GSP
15h 02m1 stop
 Logo
10:01 pm - 8:13 pmGSP-DTW
22h 12m2 stops
Thu, May 15 - Sun, May 18
Southwest Logo
1:30 pm - 8:10 pmDTW-GSP
6h 40m1 stop
Southwest Logo
6:15 pm - 10:40 pmGSP-DTW
4h 25m1 stop
$293Southwest
Find Deal
Wed, Apr 30 - Wed, May 7
Southwest Logo
5:55 am - 10:20 amDTW-GSP
4h 25m1 stop
Southwest Logo
10:55 am - 10:40 pmGSP-DTW
11h 45m2 stops
$321Southwest
Find Deal
Wed, Apr 30 - Wed, May 7
American Airlines Logo
5:21 pm - 11:38 pmDTW-GSP
6h 17m1 stop
American Airlines Logo
7:40 pm - 11:52 pmGSP-DTW
4h 12m1 stop
$327American Airlines
Find Deal
Mon, Apr 21 - Wed, Apr 23
American Airlines Logo
12:07 pm - 6:05 pmDTW-GSP
5h 58m1 stop
American Airlines Logo
8:00 am - 3:21 pmGSP-DTW
7h 21m1 stop
$344American Airlines
Find Deal
Mon, May 5 - Sat, May 10
United Airlines Logo
4:04 pm - 10:37 pmDTW-GSP
6h 33m1 stop
United Airlines Logo
6:00 am - 10:12 amGSP-DTW
4h 12m1 stop
$363United Airlines
Find Deal
Tue, Apr 29 - Wed, Apr 30
United Airlines Logo
6:00 am - 5:05 pmDTW-GSP
11h 05m2 stops
United Airlines Logo
6:02 am - 9:51 amGSP-DTW
3h 49m1 stop
$367United Airlines
Find Deal
Sat, Aug 23 - Thu, Aug 28
Delta Logo
7:00 am - 6:41 pmDTW-GSP
11h 41m1 stop
Delta Logo
6:00 am - 7:15 pmGSP-DTW
13h 15m1 stop
$375Delta
Find Deal
Sat, May 31 - Tue, Jun 10
Delta Logo
7:00 am - 6:41 pmDTW-GSP
11h 41m1 stop
Delta Logo
6:00 am - 4:34 pmGSP-DTW
10h 34m1 stop
$406Delta
Find Deal
Sat, May 31 - Fri, Jun 6

Delta flights from Detroit to Greenville

Our best Delta deals on Detroit to Greenville flight tickets
Delta
May 31
DTW7:00 amDetroit Metropolitan Wayne County
11h 41m
1 stop
GSP6:41 pmGreenville
Jun 10
GSP6:00 amGreenville
13h 15m
1 stop
DTW7:15 pmDetroit Metropolitan Wayne County
Delta
May 31
DTW7:00 amDetroit Metropolitan Wayne County
11h 41m
1 stop
GSP6:41 pmGreenville
Jun 6
GSP6:00 amGreenville
10h 34m
1 stop
DTW4:34 pmDetroit Metropolitan Wayne County
Delta
May 31
DTW7:00 amDetroit Metropolitan Wayne County
11h 41m
1 stop
GSP6:41 pmGreenville
Jun 6
GSP6:33 pmGreenville
1h 48m
DTW8:21 pmDetroit Metropolitan Wayne County

Southwest flights from Detroit to Greenville

Our best Southwest deals on Detroit to Greenville flight tickets
Southwest
Apr 30
DTW1:30 pmDetroit Metropolitan Wayne County
6h 40m
1 stop
GSP8:10 pmGreenville
May 7
GSP6:15 pmGreenville
4h 25m
1 stop
DTW10:40 pmDetroit Metropolitan Wayne County
Southwest
Apr 30
DTW5:55 amDetroit Metropolitan Wayne County
4h 25m
1 stop
GSP10:20 amGreenville
May 7
GSP10:55 amGreenville
11h 45m
2 stops
DTW10:40 pmDetroit Metropolitan Wayne County
Southwest
Jun 3
DTW5:55 amDetroit Metropolitan Wayne County
4h 25m
1 stop
GSP10:20 amGreenville
Jun 7
GSP7:20 amGreenville
9h 05m
2 stops
DTW4:25 pmDetroit Metropolitan Wayne County

See travel insights to Greenville from

How to get the cheapest flight ticket from Detroit to Greenville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Detroit and Greenville?

What is the cheapest month to fly to Greenville?

The month of August is another great option to travel to Greenville, with average flight prices from Detroit averaging around $359.

What is the cheapest day to depart on your flight to Greenville?

According to our data, Tuesday is the cheapest day to fly to Greenville from Detroit. The lowest ticket price found for a Tuesday departure recently was $427. Keep in mind that prices can always vary depending on your route and whether or not you are flying domestic or international. If your travel schedule is flexible, try to avoid departing on a Monday because tickets tend to average around $586. These prices are subject to change though, so be sure to set up a Price Alert for flights to Greenville.

What is the cheapest time of day to depart on your flight to Greenville?

Our most recent data shows that the best time of day to fly to Greenville is in the evening. Flights from Detroit to Greenville during this time can be as low as $429. Flights to Greenville are more costly in the morning, with an average ticket price of $454. Departure times in the morning fall within the peak daily travel times, which is why tickets can be more expensive.

What is the cheapest Detroit to Greenville flight route?

Fly from Detroit Metropolitan Wayne County to Greenville for the best Detroit - Greenville flight prices

How far in advance should I book a flight to Greenville?

You are more likely to see cheaper flights to Greenville from Detroit when booking 18 weeks ahead of your departure date. In general, you can expect to find flights to Greenville for around $430 when searching 18 weeks out.However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Greenville from Detroit for as low as $343 on momondo.

What cabin class options are available on Detroit to Greenville flights?

There are 4 cabin classes available to choose from on Detroit to Greenville flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

How have Detroit to Greenville flight prices changed over time?

As of April 2025, prices for Detroit to Greenville flights are approximately 8% cheaper when compared to flights at the same time last year.

When to book flights from Detroit to Greenville

Are you open to changing your travel dates? Check out the ideal times to fly from Detroit to Greenville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Detroit to Greenville (DTT to GSP) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Detroit to Greenville

Best Price Found

$108

Fastest flight time

1h 38m

Direct flights

Mon, Tue, Thu, Fri and Sat

Airports in Greenville

1 airport
The best one-way flight to Greenville from Detroit in the past 72 hours is $108. The best round-trip flight deal from Detroit to Greenville found on momondo in the last 72 hours is $266.
The fastest flight from Detroit to Greenville takes 1h 38m
Direct flights go from Detroit to Greenville on Monday, Tuesday, Thursday, Friday and Saturday. The only airline offering direct flights is Delta.
There is 1 airport near Greenville: Greenville (GSP)

  • How far is Detroit to Greenville by plane?

    There are 518.0 mi between Detroit and Greenville. By plane, this route typically takes 1h 38m.

  • When did momondo last update prices for flights from Detroit to Greenville Airport?

    Prices for flights from Detroit to Greenville Airport were last updated today.

  • How many operators does momondo search for flights from Detroit to Greenville Airport?

  • How old do you have to be to fly from Detroit to Greenville Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Detroit to Greenville Airport.

  • What documentation or ID do you need to fly to Greenville Airport?

    The travel and health documents you'll need for your trip to Greenville Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Greenville Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Detroit to Greenville?

  • What is the most popular airline from Detroit to Greenville?


Best airlines flying from Detroit to Greenville

Compare and see reviews for airlines that fly from Detroit to Greenville with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $248Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights
SouthwestPriceFrom $326Free CancellationRating
8.0
4,274 reviews
Search Southwest flights
DeltaPriceFrom $349Free CancellationRating
8.0
7,897 reviews
Search Delta flights
  • Delta Flights From Detroit to Greenville

    The lowest priced Delta flight from Detroit to Greenville from the last 72 hours was $349. Generally, Delta has 12 flights on this route every week with an average price of $442. Delta is rated 8.0/10 by our users.


Traveling to a place near Greenville?

Book flights to Greenville if you plan to visit one of these locations
Anderson
Simpsonville
Greenwood
Seneca
Greer
Duncan

Why use momondo?

Why should I use momondo to find a flight deal from Detroit to Greenville?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Detroit to Greenville. momondo saves you time and could save you money on your trip.

Can I find flights from Detroit to Greenville with flexible booking policies on momondo?

Flights from Detroit to Greenville with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Detroit to Greenville?

Once you have performed a search for Detroit to Greenville flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Detroit to Greenville right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Detroit to Greenville flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.


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