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Cheap flights from Des Moines to San Antonio from $152

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Des Moines to San Antonio departing on 5/12. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Des Moines to San Antonio

Cheap round-trip flights

KAYAK's recommended round-trip deals from the most popular airlines that fly from Des Moines to San Antonio.
Frontier Logo
7:27 pm - 4:52 pmDSM-SAT
21h 25m1 stop
Frontier Logo
8:25 pm - 6:30 pmSAT-DSM
22h 05m1 stop
$199Frontier
Find Deal
Mon, Apr 28 - Sun, May 4
Frontier Logo
7:30 pm - 6:51 pmDSM-SAT
23h 21m1 stop
Frontier Logo
7:36 pm - 7:35 pmSAT-DSM
23h 59m1 stop
$260Frontier
Find Deal
Wed, May 21 - Sun, May 25
Delta Logo
7:01 am - 11:50 amDSM-SAT
4h 49m1 stop
Delta Logo
8:00 am - 1:25 pmSAT-DSM
5h 25m1 stop
$271Delta
Find Deal
Wed, May 14 - Wed, May 21
Delta Logo
5:30 pm - 11:07 pmDSM-SAT
5h 37m1 stop
Delta Logo
6:25 am - 2:03 pmSAT-DSM
7h 38m1 stop
$284Delta
Find Deal
Sat, Jun 7 - Wed, Jun 11
Southwest Logo
6:40 am - 5:45 pmDSM-SAT
11h 05m2 stops
Southwest Logo
4:30 pm - 11:05 pmSAT-DSM
6h 35m1 stop
$298Southwest
Find Deal
Wed, May 7 - Mon, May 12
American Airlines Logo
12:49 pm - 4:43 pmDSM-SAT
3h 54m1 stop
American Airlines Logo
6:02 am - 1:41 pmSAT-DSM
7h 39m1 stop
$300American Airlines
Find Deal
Wed, Apr 30 - Thu, May 1
American Airlines Logo
6:13 pm - 11:50 pmDSM-SAT
5h 37m1 stop
American Airlines Logo
6:34 pm - 11:39 pmSAT-DSM
5h 05m1 stop
$302American Airlines
Find Deal
Thu, May 15 - Thu, May 22
United Airlines Logo
11:38 am - 7:36 pmDSM-SAT
7h 58m2 stops
United Airlines Logo
6:06 pm - 10:45 pmSAT-DSM
4h 39m1 stop
$308United Airlines
Find Deal
Tue, Apr 29 - Fri, May 2
Southwest Logo
6:30 pm - 12:45 amDSM-SAT
6h 15m2 stops
Southwest Logo
5:25 am - 1:00 pmSAT-DSM
7h 35m1 stop
$321Southwest
Find Deal
Fri, Jun 6 - Wed, Jun 11
United Airlines Logo
11:38 am - 7:36 pmDSM-SAT
7h 58m2 stops
United Airlines Logo
2:25 pm - 9:52 pmSAT-DSM
7h 27m2 stops
$363United Airlines
Find Deal
Tue, Apr 29 - Fri, May 2

Frontier flights from Des Moines to San Antonio

Our best Frontier deals on Des Moines to San Antonio flight tickets
Frontier
Apr 28
DSM7:27 pmDes Moines
21h 25m
1 stop
SAT4:52 pmSan Antonio
May 4
SAT8:25 pmSan Antonio
22h 05m
1 stop
DSM6:30 pmDes Moines
Frontier
May 21
DSM7:30 pmDes Moines
23h 21m
1 stop
SAT6:51 pmSan Antonio
May 25
SAT7:36 pmSan Antonio
23h 59m
1 stop
DSM7:35 pmDes Moines

Delta flights from Des Moines to San Antonio

Our best Delta deals on Des Moines to San Antonio flight tickets
Delta
May 14
DSM7:01 amDes Moines
4h 49m
1 stop
SAT11:50 amSan Antonio
May 21
SAT8:00 amSan Antonio
5h 25m
1 stop
DSM1:25 pmDes Moines
Delta
Jun 7
DSM5:30 pmDes Moines
5h 37m
1 stop
SAT11:07 pmSan Antonio
Jun 11
SAT6:25 amSan Antonio
7h 38m
1 stop
DSM2:03 pmDes Moines
Delta
May 7
DSM5:30 pmDes Moines
5h 39m
1 stop
SAT11:09 pmSan Antonio
May 12
SAT6:25 amSan Antonio
6h 02m
1 stop
DSM12:27 pmDes Moines

See travel insights to San Antonio from

How to get the cheapest flight ticket from Des Moines to San Antonio

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to San Antonio?

If you aren’t able to travel during the month of July, then book flights to San Antonio from Des Moines during August instead. Flights to San Antonio in August, while not as cheap as those in July, still average around $324.

What is the cheapest day to depart on your flight to San Antonio?

The cheapest day to depart on your flight to San Antonio is on a Wednesday when prices can be found for as low as $366. This is often the case because there is less demand to fly during this day of the week. Be sure to avoid booking your departure on a Monday as prices are generally higher than usual. According to our data, the average ticket price to San Antonio on Monday is $411.

What is the cheapest time of day to depart on your flight to San Antonio?

According to our data, the cheapest time of day to fly to San Antonio is in the evening. momondo users have found flights departing from Des Moines to San Antonio in the evening for as low as $301. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Flights to San Antonio are more costly in the morning, with an average ticket price of $402. Departure times in the morning fall within the peak daily travel times, which is why tickets can be more expensive.

How far in advance should I book a flight to San Antonio?

You are more likely to see cheaper flights to San Antonio from Des Moines when booking 26 weeks ahead of your departure date. In general, you can expect to find flights to San Antonio for around $389 when searching 26 weeks out.However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Antonio from Des Moines for as low as $304 on momondo.

How have Des Moines to San Antonio flight prices changed over time?

As of April 2025, prices for Des Moines to San Antonio flights are approximately 97% more expensive when compared to flights at the same time last year.

When to book flights from Des Moines to San Antonio

Are you open to changing your travel dates? Check out the ideal times to fly from Des Moines to San Antonio according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Des Moines to San Antonio (DSM to SAT) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to San Antonio

Best Price Found

$152

Fastest flight time

3h 54m

Direct flights

None

Airports in San Antonio

1 airport
The best one-way flight to San Antonio from Des Moines in the past 72 hours is $152. The best round-trip flight deal from Des Moines to San Antonio found on momondo in the last 72 hours is $199.
The fastest flight from Des Moines to San Antonio takes 3h 54m
There are no direct flights from Des Moines to San Antonio. Popular non-direct route for this connection is Des Moines Airport - San Antonio Airport.
There is 1 airport near San Antonio: San Antonio (SAT)

  • How far is Des Moines to San Antonio by plane?

    Des Moines and San Antonio are 882.7 mi apart from one another. In terms of flight time, this usually takes a little over 3h 54m.

  • When did momondo last update prices for flights from Des Moines Airport to San Antonio Airport?

    Prices for flights from Des Moines Airport to San Antonio Airport are updated daily.

  • How many operators does momondo search for flights from Des Moines Airport to San Antonio Airport?

  • How old do you have to be to fly from Des Moines Airport to San Antonio Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Des Moines Airport to San Antonio Airport.

  • What documentation or ID do you need to fly to San Antonio Airport?

    The necessary travel and health documents for your San Antonio Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Des Moines to San Antonio?


Best airlines flying from Des Moines to San Antonio

Compare and see reviews for airlines that fly from Des Moines to San Antonio with momondo
Airline
Rating
Free Cancellation
Price
FrontierPriceFrom $111Free CancellationRating
5.9
3,277 reviews
Search Frontier flights
American AirlinesPriceFrom $284Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights
United AirlinesPriceFrom $286Free CancellationRating
7.4
8,615 reviews
Search United Airlines flights
DeltaPriceFrom $292Free CancellationRating
8.0
7,899 reviews
Search Delta flights
SouthwestPriceFrom $331Free CancellationRating
8.0
4,275 reviews
Search Southwest flights

Traveling to a place near San Antonio?

Book flights to San Antonio if you plan to visit one of these locations
New Braunfels
Kerrville
Schertz
Boerne
Pleasanton

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to San Antonio?

Finding the right flight to San Antonio from Des Moines is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to San Antonio quick and easy, saving you time and money.

Can I find flights from Des Moines to San Antonio with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Des Moines to San Antonio flights to just show those with flexible booking policies.

How can momondo help me find flights from Des Moines to San Antonio?

momondo provides multiple filters to help you find the best flight to San Antonio from Des Moines. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Des Moines to San Antonio right now. Can momondo alert me if prices change?

Price alerts on flights to San Antonio from Des Moines are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.


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