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Cheap flights from Chicago to Knoxville from $51

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Chicago to Knoxville departing on 6/6. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Chicago to Knoxville

Cheap round-trip flights

KAYAK's recommended round-trip deals from the most popular airlines that fly from Chicago to Knoxville.
7:00 pm - 9:28 pmMDW-TYS
1h 28mnonstop
5:37 pm - 6:10 pmTYS-MDW
1h 33mnonstop
$80Allegiant Air
Find Deal
Fri, May 30 - Mon, Jun 2
2:53 pm - 5:18 pmMDW-TYS
1h 25mnonstop
1:29 pm - 2:03 pmTYS-MDW
1h 34mnonstop
$83Allegiant Air
Find Deal
Fri, Jun 27 - Mon, Jun 30
6:45 am - 3:41 pmORD-TYS
7h 56m1 stop
4:43 pm - 12:10 amTYS-ORD
8h 27m1 stop
$178Frontier
Find Deal
Thu, Apr 17 - Sun, Apr 20
6:45 am - 3:41 pmMDW-TYS
7h 56m1 stop
12:46 pm - 12:21 amTYS-MDW
12h 35m1 stop
$178Frontier
Find Deal
Thu, Apr 17 - Fri, Apr 18
10:35 am - 1:22 pmORD-TYS
1h 47mnonstop
1:06 pm - 1:59 pmTYS-ORD
1h 53mnonstop
$179American Airlines
Find Deal
Tue, Jun 24 - Fri, Jul 4
8:27 am - 11:10 amORD-TYS
1h 43mnonstop
7:50 pm - 8:53 pmTYS-ORD
2h 03mnonstop
$180American Airlines
Find Deal
Wed, May 14 - Wed, May 21
7:58 pm - 10:45 pmORD-TYS
1h 47mnonstop
7:00 am - 7:57 amTYS-ORD
1h 57mnonstop
$184United Airlines
Find Deal
Fri, May 2 - Tue, May 6
7:58 pm - 10:45 pmORD-TYS
1h 47mnonstop
5:50 am - 9:44 amTYS-ORD
4h 54m1 stop
$194United Airlines
Find Deal
Fri, May 2 - Tue, May 6
6:45 am - 12:03 pmORD-TYS
4h 18m1 stop
7:50 am - 12:41 pmTYS-ORD
5h 51m1 stop
$199Delta
Find Deal
Wed, Apr 30 - Wed, May 7
6:04 am - 11:09 amMDW-TYS
4h 05m1 stop
5:30 am - 9:07 amTYS-MDW
4h 37m1 stop
$199Delta
Find Deal
Wed, Apr 30 - Tue, May 6

Frontier flights from Chicago to Knoxville

Our best Frontier deals on Chicago to Knoxville flight tickets
Frontier
Apr 17
ORD6:45 amChicago O'Hare Intl
7h 56m
1 stop
TYS3:41 pmKnoxville McGhee Tyson
Apr 20
TYS4:43 pmKnoxville McGhee Tyson
8h 27m
1 stop
ORD12:10 amChicago O'Hare Intl
Frontier
Apr 10
ORD6:45 amChicago O'Hare Intl
7h 56m
1 stop
TYS3:41 pmKnoxville McGhee Tyson
Apr 13
TYS4:43 pmKnoxville McGhee Tyson
8h 27m
1 stop
ORD12:10 amChicago O'Hare Intl
Frontier
Apr 3
MDW6:40 amChicago Midway
8h 01m
1 stop
TYS3:41 pmKnoxville McGhee Tyson
Apr 6
TYS4:43 pmKnoxville McGhee Tyson
8h 38m
1 stop
MDW12:21 amChicago Midway

Delta flights from Chicago to Knoxville

Our best Delta deals on Chicago to Knoxville flight tickets
Delta
Apr 30
MDW6:04 amChicago Midway
4h 05m
1 stop
TYS11:09 amKnoxville McGhee Tyson
May 6
TYS5:30 amKnoxville McGhee Tyson
4h 37m
1 stop
MDW9:07 amChicago Midway
Delta
May 2
ORD5:05 pmChicago O'Hare Intl
3h 25m
1 stop
TYS9:30 pmKnoxville McGhee Tyson
May 6
TYS5:30 amKnoxville McGhee Tyson
5h 33m
1 stop
ORD10:03 amChicago O'Hare Intl
Delta
Apr 16
MDW6:04 amChicago Midway
4h 05m
1 stop
TYS11:09 amKnoxville McGhee Tyson
Apr 19
TYS7:48 amKnoxville McGhee Tyson
5h 47m
1 stop
MDW12:35 pmChicago Midway

See travel insights to Knoxville from

How to get the cheapest flight ticket from Chicago to Knoxville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Knoxville?

The month of August is, on average, the cheapest month to fly to Knoxville from Chicago, with most prices found around $213. If you aren’t able to travel during the month of August, then book flights to Knoxville from Chicago during September instead. Flights to Knoxville in September, while not as cheap as those in August, still average around $224.

What is the cheapest day to depart on your flight to Knoxville?

The cheapest day to depart from Chicago to Knoxville is on a Monday. Travelers who choose to depart for Knoxville on a Monday will often find tickets for as low as $250. When flying out on a Sunday, the most expensive travel day of the week, you can expect to see flight prices from Chicago to Knoxville for around $318.

What is the cheapest time of day to depart on your flight to Knoxville?

In the evening is the cheapest time of day to fly from Chicago to Knoxville when you can find flight prices for as low as $237. Flying to Knoxville in the evening is an ideal time because this is during off-peak travel hours. In contrast, the most expensive time of day to depart to Knoxville is in the morning when prices are around $300.

What is the cheapest Chicago to Knoxville McGhee Tyson flight route?

Fly from Chicago Midway to Knoxville McGhee Tyson for the best Chicago - Knoxville McGhee Tyson flight prices

How far in advance should I book a flight to Knoxville?

You are more likely to see cheaper flights to Knoxville from Chicago when booking 18 weeks ahead of your departure date. In general, you can expect to find flights to Knoxville for around $293 when searching 18 weeks out.However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Knoxville from Chicago for as low as $241 on momondo.

What cabin class options are available on Chicago to Knoxville McGhee Tyson flights?

There are 3 cabin classes available to choose from on Chicago to Knoxville McGhee Tyson flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

How have Chicago to Knoxville flight prices changed over time?

As of March 2025, prices for Chicago to Knoxville flights are approximately 37% cheaper when compared to flights at the same time last year.

When to book flights from Chicago to Knoxville

Are you open to changing your travel dates? Check out the ideal times to fly from Chicago to Knoxville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Chicago to Knoxville (CHI to TYS) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Chicago to Knoxville

Best Price Found

$51

Fastest flight time

1h 25m

Direct flights

Every day

Airports in Knoxville

1 airport
The best one-way flight to Knoxville from Chicago in the past 72 hours is $51. The best round-trip flight deal from Chicago to Knoxville found on momondo in the last 72 hours is $80.
The fastest flight from Chicago to Knoxville takes 1h 25m
Direct flights go from Chicago to Knoxville every day.
There is 1 airport near Knoxville: Knoxville McGhee Tyson (TYS)

  • How far is Chicago to Knoxville McGhee Tyson by plane?

    There are 454.2 mi between Chicago and Knoxville McGhee Tyson. 1h 25m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Chicago to Knoxville McGhee Tyson Airport?

    Prices for flights from Chicago to Knoxville McGhee Tyson Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Chicago to Knoxville McGhee Tyson Airport?

  • How old do you have to be to fly from Chicago to Knoxville McGhee Tyson Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Chicago to Knoxville McGhee Tyson Airport.

  • What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?

    The required travel and health documents for your Knoxville McGhee Tyson Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Knoxville McGhee Tyson Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular plane model from Chicago to Knoxville?

  • What is the most popular airline from Chicago to Knoxville?


Best airlines flying from Chicago to Knoxville

Compare and see reviews for airlines that fly from Chicago to Knoxville with momondo
Airline
Rating
Free Cancellation
Price
Allegiant AirPriceFrom $59Free CancellationRating
7.3
731 reviews
Search Allegiant Air flights
DeltaPriceFrom $160Free CancellationRating
8.0
7,899 reviews
Search Delta flights
American AirlinesPriceFrom $169Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights
United AirlinesPriceFrom $180Free CancellationRating
7.4
8,614 reviews
Search United Airlines flights
  • United Airlines Flights From Chicago to Knoxville

    United Airlines flies from Chicago to Knoxville around 10 times per week, with 8,614 momondo users rating the airline 7.4/10. The cheapest United Airlines deal from Chicago to Knoxville in the last 72 hours was $180 (round-trip), much lower than the average airfare cost of $310 for United Airlines flights on this route.

  • American Airlines Flights From Chicago to Knoxville

    The best American Airlines deal for Chicago to Knoxville flight tickets found on momondo in the last 72 hours was $169, round-trip. It should be noted that an average American Airlines flight deal for this route in this time was higher, at $284 round-trip. American Airlines operates 11 flights out of Chicago into Knoxville in an average week, so prices vary by time and availability. 10,000 American Airlines reviews by users on momondo have scored the airline at 7.2/10.


Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Pigeon Forge
Gatlinburg
Cherokee
Bryson City
Morristown
Corbin
Murphy
Crossville
Maryville
Newport
Alcoa
Oak Ridge
Kodak
Lenoir City
Dandridge
Clinton
Jefferson City
Rockford

Why use momondo?

Why should I use momondo to find a flight deal from Chicago to Knoxville?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Chicago to Knoxville. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Chicago to Knoxville with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Knoxville from Chicago with this policy.

How can momondo help me find flights from Chicago to Knoxville?

momondo provides multiple filters to help you find the best flight to Knoxville from Chicago. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Chicago to Knoxville right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Knoxville from Chicago. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.


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