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Cheap flights from Buffalo to Knoxville from $219

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Buffalo to Knoxville departing on 1/1. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Buffalo to Knoxville

Cheap round-trip flights

These are some of the best round-trip flight deals from Buffalo to Knoxville that have been recently found on momondo from popular airlines, departing in the coming months.

Cheap one-way flights

Flying one-way? These are some of the best deals recently discovered on momondo for flights from Buffalo to Knoxville.

Cheap last minute flights

Planning a quick getaway from Buffalo to Knoxville? These are the last-minute flight deals available now.

Cheap direct flights

If you prefer a non-stop journey, check out our latest direct flight deals to Knoxville, so you can enjoy a seamless trip without layovers.

Cheap bus & train deals from Buffalo to Knoxville

Find recent round-trip train or bus tickets from Buffalo to Knoxville.

All round-trip flight deals to Knoxville

The cheapest plane tickets to Knoxville found on KAYAK recently.
12:23 pm - 5:38 pmBUF-TYS
5h 15m1 stop
6:26 pm - 11:05 pmTYS-BUF
4h 39m1 stop
$248American Airlines
Find Deal
Sun, Dec 15 - Sun, Dec 22
4:37 pm - 8:59 pmBUF-TYS
4h 22m1 stop
8:02 pm - 12:10 amTYS-BUF
4h 08m1 stop
$258American Airlines
Find Deal
Tue, Dec 3 - Sat, Dec 7
4:37 pm - 8:59 pmBUF-TYS
4h 22m1 stop
9:07 am - 4:29 pmTYS-BUF
7h 22m2 stops
$263American Airlines
Find Deal
Tue, Dec 3 - Sat, Dec 7
12:47 pm - 5:36 pmBUF-TYS
4h 49m1 stop
5:00 am - 10:42 amTYS-BUF
5h 42m1 stop
$278American Airlines
Find Deal
Fri, Dec 20 - Tue, Dec 24
7:50 pm - 2:41 pmBUF-TYS
18h 51m2 stops
7:24 pm - 11:46 pmTYS-BUF
4h 22m1 stop
$439United Airlines
Find Deal
Sun, Dec 15 - Sun, Dec 22
6:05 am - 10:39 amBUF-TYS
4h 34m1 stop
7:24 pm - 11:46 pmTYS-BUF
4h 22m1 stop
$443United Airlines
Find Deal
Tue, Dec 24 - Sat, Dec 28
7:50 pm - 1:23 pmBUF-TYS
17h 33m2 stops
7:00 am - 6:17 pmTYS-BUF
11h 17m2 stops
$531United Airlines
Find Deal
Tue, Dec 3 - Sat, Dec 7
2:10 pm - 9:04 pmBUF-TYS
6h 54m1 stop
5:50 pm - 11:30 pmTYS-BUF
5h 40m1 stop
$843Delta
Find Deal
Mon, Dec 2 - Fri, Dec 6
6:00 am - 10:56 amBUF-TYS
4h 56m1 stop
5:50 pm - 11:30 pmTYS-BUF
5h 40m1 stop
$943Delta
Find Deal
Sun, Dec 1 - Fri, Dec 6
2:10 pm - 9:04 pmBUF-TYS
6h 54m1 stop
5:20 am - 11:15 amTYS-BUF
5h 55m2 stops
$1,456Delta
Find Deal
Mon, Dec 2 - Fri, Dec 6
6:00 am - 11:14 amBUF-TYS
5h 14m1 stop
$219American Airlines
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Wed, Jan 1
6:00 am - 10:29 amBUF-TYS
4h 29m1 stop
$294American Airlines
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Sat, Dec 7
6:07 am - 2:21 pmBUF-TYS
8h 14m2 stops
$299American Airlines
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Sat, Dec 7
6:00 am - 4:54 pmBUF-TYS
10h 54m2 stops
$353United Airlines
Find Deal
Wed, Jan 1
6:06 am - 10:32 amBUF-TYS
4h 26m1 stop
$454American Airlines
Find Deal
Sun, Dec 1
10:00 pm - 7:30 pmBUF-TYS
21h 30m2 stops
$866United Airlines
Find Deal
Sun, Dec 1
6:07 am - 10:32 amBUF-TYS
4h 25m1 stop
7:23 pm - 11:46 pmTYS-BUF
4h 23m1 stop
$553American Airlines
Find Deal
Thu, Nov 21 - Fri, Nov 29
6:00 am - 4:55 pmBUF-TYS
10h 55m2 stops
2:35 pm - 9:56 amTYS-BUF
19h 21m1 stop
$678United Airlines
Find Deal
Thu, Nov 21 - Fri, Nov 29
5:50 pm - 10:24 pmBUF-TYS
4h 34m1 stop
2:35 pm - 11:14 pmTYS-BUF
8h 39m2 stops
$808United Airlines
Find Deal
Fri, Nov 22 - Fri, Nov 29
6:00 am - 4:55 pmBUF-TYS
10h 55m2 stops
2:35 pm - 11:14 pmTYS-BUF
8h 39m2 stops
$813United Airlines
Find Deal
Thu, Nov 21 - Fri, Nov 29
5:50 pm - 10:24 pmBUF-TYS
4h 34m1 stop
7:00 am - 11:14 pmTYS-BUF
16h 14m3 stops
$1,351United Airlines
Find Deal
Fri, Nov 22 - Fri, Nov 29

American Airlines flights from Buffalo to Knoxville

Our best American Airlines deals on Buffalo to Knoxville flight tickets
American Airlines
Dec 15
BUF12:23 pmBuffalo
5h 15m
1 stop
TYS5:38 pmKnoxville McGhee Tyson
Dec 22
TYS6:26 pmKnoxville McGhee Tyson
4h 39m
1 stop
BUF11:05 pmBuffalo
American Airlines
Dec 3
BUF4:37 pmBuffalo
4h 22m
1 stop
TYS8:59 pmKnoxville McGhee Tyson
Dec 7
TYS8:02 pmKnoxville McGhee Tyson
4h 08m
1 stop
BUF12:10 amBuffalo
American Airlines
Dec 3
BUF4:37 pmBuffalo
4h 22m
1 stop
TYS8:59 pmKnoxville McGhee Tyson
Dec 7
TYS9:07 amKnoxville McGhee Tyson
7h 22m
2 stops
BUF4:29 pmBuffalo

United Airlines flights from Buffalo to Knoxville

Our best United Airlines deals on Buffalo to Knoxville flight tickets
United Airlines
Dec 15
BUF7:50 pmBuffalo
18h 51m
2 stops
TYS2:41 pmKnoxville McGhee Tyson
Dec 22
TYS7:24 pmKnoxville McGhee Tyson
4h 22m
1 stop
BUF11:46 pmBuffalo
United Airlines
Dec 24
BUF6:05 amBuffalo
4h 34m
1 stop
TYS10:39 amKnoxville McGhee Tyson
Dec 28
TYS7:24 pmKnoxville McGhee Tyson
4h 22m
1 stop
BUF11:46 pmBuffalo
United Airlines
Dec 3
BUF7:50 pmBuffalo
17h 33m
2 stops
TYS1:23 pmKnoxville McGhee Tyson
Dec 7
TYS7:00 amKnoxville McGhee Tyson
11h 17m
2 stops
BUF6:17 pmBuffalo

How to get the cheapest flight ticket from Buffalo to Knoxville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly from Buffalo to Knoxville?

September. The cheapest time of year to fly to Knoxville from Buffalo is September. Most expensive is May

What is the cheapest day to depart Buffalo for Knoxville?

Tuesday. The cheapest day of the week is typically Tuesday. The most expensive is typically Monday

When is the cheapest time to fly from Buffalo to Knoxville?

In the evening. Buffalo to Knoxville flights are approximately 32% more expensive at noon than in the evening

What is the cheapest airline that flies to Knoxville from Buffalo?

Delta. Delta, American Airlines, and United Airlines are the most popular carriers operating from Buffalo to Knoxville

What is the cheapest Buffalo to Knoxville flight route?

Buffalo - Knoxville McGhee Tyson. Fly from Buffalo to Knoxville McGhee Tyson for the best Buffalo - Knoxville flight prices

How far in advance should you book Buffalo to Knoxville flights?

51 days before. The cheapest time to buy a flight from Buffalo to Knoxville is approximately 51 days to departure

Can stopping save me money on Buffalo to Knoxville flights?

You could potentially save up to 26% on your flight if you consider stops on a Buffalo to Knoxville flight.

How have Buffalo to Knoxville flight prices changed over time?

As of November 2024, prices for Buffalo to Knoxville flights are approximately 73% more expensive when compared to flights at the same time last year.

When to book flights from Buffalo to Knoxville

Are you open to changing your travel dates? Check out the ideal times to fly from Buffalo to Knoxville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Buffalo to Knoxville (BUF to TYS) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Buffalo to Knoxville

Best Price Found

$219

Fastest flight time

4h 22m

Direct flights

None

Airports in Knoxville

1 airport
The best one-way flight to Knoxville from Buffalo in the past 72 hours is $219. The best round-trip flight deal from Buffalo to Knoxville found on momondo in the last 72 hours is $248.
The fastest flight from Buffalo to Knoxville takes 4h 22m
There are no direct flights from Buffalo to Knoxville. Popular non-direct route for this connection is Buffalo Airport - Knoxville McGhee Tyson Airport.
There is 1 airport near Knoxville: Knoxville McGhee Tyson (TYS)

  • How far is Buffalo to Knoxville McGhee Tyson by plane?

    The distance between Buffalo and Knoxville McGhee Tyson is about 548.4 mi. By plane, this route typically takes 4h 22m.

  • When did momondo last update prices for flights from Buffalo Airport to Knoxville McGhee Tyson Airport?

    Prices for flights from Buffalo Airport to Knoxville McGhee Tyson Airport refresh daily.

  • How many operators does momondo search for flights from Buffalo Airport to Knoxville McGhee Tyson Airport?

  • How old do you have to be to fly from Buffalo Airport to Knoxville McGhee Tyson Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Buffalo Airport to Knoxville McGhee Tyson Airport.

  • What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?

    The travel and health documents required for your trip to Knoxville McGhee Tyson Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Knoxville McGhee Tyson Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular airline from Buffalo to Knoxville?


Best airlines flying from Buffalo to Knoxville

Compare and see reviews for airlines that fly from Buffalo to Knoxville with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $208Free CancellationRating
8.0
8,766 reviews
Search Delta flights
American AirlinesPriceFrom $211Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights
United AirlinesPriceFrom $238Free CancellationRating
7.4
9,168 reviews
Search United Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Buffalo to Knoxville?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Buffalo to Knoxville for you.

Can I find flights from Buffalo to Knoxville with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Buffalo to Knoxville flights to just show those with flexible booking policies.

How can momondo help me find flights from Buffalo to Knoxville?

momondo helps you find the best flight between Buffalo and Knoxville by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Buffalo to Knoxville right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Buffalo to Knoxville flights. All you need is a valid email address and we will do the rest; it is that quick and easy.


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