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Cheap flights from Portland, Maine to Santiago de los Caballeros from $407

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Portland, Maine to Santiago de los Caballeros departing on 3/18. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Portland, Maine to Santiago de los Caballeros

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
6:29 pm - 12:30 pm
PWM
-
STI
18h 01m2 stops
American Airlines Logo
1:30 pm - 11:19 am
STI
-
PWM
21h 49m2 stops
$407American Airlines
Wed, Mar 18 - Sat, Mar 28
United Airlines Logo
4:10 pm - 2:53 pm
PWM
-
STI
21h 43m2 stops
United Airlines Logo
4:00 pm - 11:21 pm
STI
-
PWM
8h 21m1 stop
$452United Airlines
Sat, Feb 7 - Wed, Feb 11
United Airlines Logo
4:10 pm - 2:53 pm
PWM
-
STI
21h 43m2 stops
United Airlines Logo
4:00 pm - 11:21 pm
STI
-
PWM
8h 21m1 stop
$453United Airlines
Sat, Feb 7 - Wed, Feb 11
United Airlines Logo
4:10 pm - 2:53 pm
PWM
-
STI
21h 43m2 stops
United Airlines Logo
6:00 am - 3:14 pm
STI
-
PWM
34h 14m2 stops
$556United Airlines
Sat, Feb 7 - Wed, Feb 11
United Airlines Logo
4:10 pm - 2:53 pm
PWM
-
STI
21h 43m2 stops
United Airlines Logo
6:00 am - 3:14 pm
STI
-
PWM
34h 14m2 stops
$557United Airlines
Sat, Feb 7 - Wed, Feb 11
United Airlines Logo
3:05 pm - 11:51 pm
PWM
-
STI
7h 46m1 stop
United Airlines Logo
4:00 pm - 11:21 pm
STI
-
PWM
8h 21m1 stop
$608United Airlines
Sat, Feb 7 - Wed, Feb 11
United Airlines Logo
6:00 am - 2:53 pm
PWM
-
STI
7h 53m1 stop
United Airlines Logo
4:00 pm - 11:21 pm
STI
-
PWM
8h 21m1 stop
$609United Airlines
Sat, Feb 7 - Wed, Feb 11
United Airlines Logo
6:00 am - 1:53 pm
PWM
-
STI
7h 53m1 stop
United Airlines Logo
3:00 pm - 10:52 pm
STI
-
PWM
7h 52m1 stop
$637United Airlines
Wed, Mar 18 - Sat, Mar 28
United Airlines Logo
6:00 am - 1:53 pm
PWM
-
STI
7h 53m1 stop
United Airlines Logo
3:00 pm - 10:22 am
STI
-
PWM
19h 22m2 stops
$641United Airlines
Wed, Mar 18 - Sat, Mar 28
American Airlines Logo
7:00 am - 8:29 pm
PWM
-
STI
13h 29m3 stops
American Airlines Logo
7:00 am - 10:50 pm
STI
-
PWM
15h 50m2 stops
$2,189American Airlines
Wed, Mar 18 - Sat, Mar 28

United Airlines flights from Portland, Maine to Santiago de los Caballeros

Our best United Airlines deals on Portland, Maine to Santiago de los Caballeros flight tickets
United Airlines
Feb 7
PWM4:10 pmPortland
21h 43m
2 stops
STI2:53 pmSantiago de los Caballeros
Feb 11
STI4:00 pmSantiago de los Caballeros
8h 21m
1 stop
PWM11:21 pmPortland
$452
Find similar
United Airlines
Feb 7
PWM4:10 pmPortland
21h 43m
2 stops
STI2:53 pmSantiago de los Caballeros
Feb 11
STI4:00 pmSantiago de los Caballeros
8h 21m
1 stop
PWM11:21 pmPortland
$453
Find similar
United Airlines
Feb 7
PWM4:10 pmPortland
21h 43m
2 stops
STI2:53 pmSantiago de los Caballeros
Feb 11
STI6:00 amSantiago de los Caballeros
34h 14m
2 stops
PWM3:14 pmPortland
$556
Find similar

American Airlines flights from Portland, Maine to Santiago de los Caballeros

Our best American Airlines deals on Portland, Maine to Santiago de los Caballeros flight tickets
American Airlines
Mar 18
PWM6:29 pmPortland
18h 01m
2 stops
STI12:30 pmSantiago de los Caballeros
Mar 28
STI1:30 pmSantiago de los Caballeros
21h 49m
2 stops
PWM11:19 amPortland
$407
Find similar
American Airlines
Mar 18
PWM7:00 amPortland
13h 29m
3 stops
STI8:29 pmSantiago de los Caballeros
Mar 28
STI7:00 amSantiago de los Caballeros
15h 50m
2 stops
PWM10:50 pmPortland
$2,189
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Portland, Maine to Santiago de los Caballeros that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated January 2, 2026.
Use the filters below to find and compare flights from Portland, Maine to Santiago de los Caballeros that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

PortlandSantiago de los Caballeros

PWM - STI

PWMSTI

Portland

Wed 3/18

6:29 pm-12:30 pm

2 stops18h 01m

Santiago de los Caballeros

Sat 3/28

1:30 pm-11:19 am

2 stops21h 49m

$407

PortlandSantiago de los Caballeros

PWM - STI

PWMSTI

Portland

Sat 2/7

4:10 pm-2:53 pm

2 stops21h 43m

Santiago de los Caballeros

Wed 2/11

4:00 pm-11:21 pm

1 stop8h 21m

$452

PortlandSantiago de los Caballeros

PWM - STI

PWMSTI

Portland

Sat 2/7

4:10 pm-2:53 pm

2 stops21h 43m

Santiago de los Caballeros

Wed 2/11

4:00 pm-11:21 pm

1 stop8h 21m

$453

PortlandSantiago de los Caballeros

PWM - STI

PWMSTI

Portland

Sat 2/7

4:10 pm-2:53 pm

2 stops21h 43m

Santiago de los Caballeros

Wed 2/11

6:00 am-3:14 pm

2 stops34h 14m

$556

PortlandSantiago de los Caballeros

PWM - STI

PWMSTI

Portland

Sat 2/7

4:10 pm-2:53 pm

2 stops21h 43m

Santiago de los Caballeros

Wed 2/11

6:00 am-3:14 pm

2 stops34h 14m

$557

PortlandSantiago de los Caballeros

PWM - STI

PWMSTI

Portland

Sat 2/7

3:05 pm-11:51 pm

1 stop7h 46m

Santiago de los Caballeros

Wed 2/11

4:00 pm-11:21 pm

1 stop8h 21m

$608

PortlandSantiago de los Caballeros

PWM - STI

PWMSTI

Portland

Sat 2/7

6:00 am-2:53 pm

1 stop7h 53m

Santiago de los Caballeros

Wed 2/11

4:00 pm-11:21 pm

1 stop8h 21m

$609

PortlandSantiago de los Caballeros

PWM - STI

PWMSTI

Portland

Wed 3/18

6:00 am-1:53 pm

1 stop7h 53m

Santiago de los Caballeros

Sat 3/28

3:00 pm-10:52 pm

1 stop7h 52m

$637

PortlandSantiago de los Caballeros

PWM - STI

PWMSTI

Portland

Wed 3/18

6:00 am-1:53 pm

1 stop7h 53m

Santiago de los Caballeros

Sat 3/28

3:00 pm-10:22 am

2 stops19h 22m

$641

PortlandSantiago de los Caballeros

PWM - STI

PWMSTI

Portland

Wed 3/18

7:00 am-8:29 pm

3 stops13h 29m

Santiago de los Caballeros

Sat 3/28

7:00 am-10:50 pm

2 stops15h 50m

$2,189

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to Santiago de los Caballeros from

How to get the cheapest flight ticket from Portland, Maine to Santiago de los Caballeros

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What airlines fly to Santiago de los Caballeros?

JetBlue, Arajet and American Airlines are the top three most popular airlines that fly to Santiago de los Caballeros from Portland, Maine according to our data. JetBlue is the first choice among our users, with 87% of people opting to fly with this airline when traveling to Santiago de los Caballeros. Keep in mind that there are 9 different airlines that fly to Santiago de los Caballeros on a routine basis, so you have a few additional options to choose from.

When to book flights from Portland, Maine to Santiago de los Caballeros

Are you open to changing your travel dates? Check out the ideal times to fly from Portland, Maine to Santiago de los Caballeros according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Portland, Maine to Santiago de los Caballeros (PWM to STI) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Portland, Maine to Santiago de los Caballeros

Fastest flight time

7h 53m

Direct flights

None
The fastest flight from Portland, Maine to Santiago de los Caballeros takes 7h 53m
There are no direct flights from Portland, Maine to Santiago de los Caballeros. There are no popular flight routes from Portland, Maine to Santiago de los Caballeros.
Search flight deals

  • How far is Portland to Santiago de los Caballeros by plane?

    The straight-line distance from Portland to Santiago de los Caballeros is 1671.8 mi. By plane, this route typically takes 7h 53m.

  • When did momondo last update prices for flights from Portland Airport to Santiago de los Caballeros Airport?

    Prices for flights from Portland Airport to Santiago de los Caballeros Airport refresh daily.

  • How old do you have to be to fly from Portland Airport to Santiago de los Caballeros Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Portland Airport to Santiago de los Caballeros Airport.

  • What documentation or ID do you need to fly to Santiago de los Caballeros Airport?

    The travel and health documents you'll need for your trip to Santiago de los Caballeros Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Santiago de los Caballeros Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Why use momondo?

Why should I use momondo to find a flight deal from Portland to Santiago de los Caballeros?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Portland to Santiago de los Caballeros. momondo saves you time and could save you money on your trip.

Can I find flights from Portland to Santiago de los Caballeros with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Santiago de los Caballeros from Portland with this policy.

How can momondo help me find flights from Portland to Santiago de los Caballeros?

Once all potential Portland to Santiago de los Caballeros flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Portland to Santiago de los Caballeros right now. Can momondo alert me if prices change?

Price alerts on flights to Santiago de los Caballeros from Portland are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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