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Cheap flights from Portland, Maine to Santiago de los Caballeros from $455

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Portland, Maine to Santiago de los Caballeros departing on 10/15. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Portland, Maine to Santiago de los Caballeros

Cheap round-trip flights

JetBlue Logo
2:17 pm - 2:21 amPWM-STI
12h 04m1 stop
JetBlue Logo
12:48 pm - 11:04 pmSTI-PWM
10h 16m1 stop
$455JetBlue
Find Deal
Wed, Oct 15 - Wed, Oct 22
United Airlines Logo
6:00 am - 12:57 pmPWM-STI
6h 57m1 stop
United Airlines Logo
6:00 am - 9:44 pmSTI-PWM
15h 44m2 stops
$542United Airlines
Find Deal
Wed, Oct 15 - Wed, Oct 22
Delta Logo
6:30 am - 6:46 pmPWM-STI
11h 16m1 stop
Delta Logo
2:33 pm - 11:49 pmSTI-PWM
10h 16m1 stop
$704Delta
Find Deal
Mon, Feb 23 - Sun, Mar 1
Delta Logo
12:50 pm - 11:54 pmPWM-STI
10h 04m2 stops
Delta Logo
2:33 pm - 11:49 pmSTI-PWM
10h 16m1 stop
$709Delta
Find Deal
Mon, Feb 23 - Sun, Mar 1

Delta flights from Portland, Maine to Santiago de los Caballeros

Our best Delta deals on Portland, Maine to Santiago de los Caballeros flight tickets
Delta
Feb 23
PWM6:30 amPortland
11h 16m
1 stop
STI6:46 pmSantiago de los Caballeros
Mar 1
STI2:33 pmSantiago de los Caballeros
10h 16m
1 stop
PWM11:49 pmPortland
$704
Find similar
Delta
Feb 23
PWM12:50 pmPortland
10h 04m
2 stops
STI11:54 pmSantiago de los Caballeros
Mar 1
STI2:33 pmSantiago de los Caballeros
10h 16m
1 stop
PWM11:49 pmPortland
$709
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Portland, Maine to Santiago de los Caballeros that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated September 17, 2025.
Use the filters below to find and compare flights from Portland, Maine to Santiago de los Caballeros that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

PortlandSantiago de los Caballeros

PWM - STI

PWMSTI

Portland

Wed 10/15

2:17 pm-2:21 am

1 stop12h 04m

Santiago de los Caballeros

Wed 10/22

12:48 pm-11:04 pm

1 stop10h 16m

$455

PortlandSantiago de los Caballeros

PWM - STI

PWMSTI

Portland

Wed 10/15

6:00 am-12:57 pm

1 stop6h 57m

Santiago de los Caballeros

Wed 10/22

6:00 am-9:44 pm

2 stops15h 44m

$542

PortlandSantiago de los Caballeros

PWM - STI

PWMSTI

Portland

Mon 2/23

6:30 am-6:46 pm

1 stop11h 16m

Santiago de los Caballeros

Sun 3/1

2:33 pm-11:49 pm

1 stop10h 16m

$704

PortlandSantiago de los Caballeros

PWM - STI

PWMSTI

Portland

Mon 2/23

12:50 pm-11:54 pm

2 stops10h 04m

Santiago de los Caballeros

Sun 3/1

2:33 pm-11:49 pm

1 stop10h 16m

$709

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to Santiago de los Caballeros from

How to get the cheapest flight ticket from Portland, Maine to Santiago de los Caballeros

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Santiago de los Caballeros?

The cheapest day to depart from Portland, Maine to Santiago de los Caballeros is on a Thursday when prices can be found for as low as $475. When flying out on a Friday, the most expensive travel day of the week, you can expect to see flight prices from Portland, Maine to Santiago de los Caballeros for around $645.

When to book flights from Portland, Maine to Santiago de los Caballeros

Are you open to changing your travel dates? Check out the ideal times to fly from Portland, Maine to Santiago de los Caballeros according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Portland, Maine to Santiago de los Caballeros (PWM to STI) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Portland, Maine to Santiago de los Caballeros

Direct flights

None
There are no direct flights from Portland, Maine to Santiago de los Caballeros. There are no popular flight routes from Portland, Maine to Santiago de los Caballeros.
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  • How far is Portland to Santiago de los Caballeros by plane?

    The straight-line distance from Portland to Santiago de los Caballeros is 1671.8 mi. By plane, this route typically takes 6h 57m.

  • When did momondo last update prices for flights from Portland Airport to Santiago de los Caballeros Airport?

    Prices for flights from Portland Airport to Santiago de los Caballeros Airport refresh daily.

  • How old do you have to be to fly from Portland Airport to Santiago de los Caballeros Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Portland Airport to Santiago de los Caballeros Airport.

  • What documentation or ID do you need to fly to Santiago de los Caballeros Airport?

    The travel and health documents you'll need for your trip to Santiago de los Caballeros Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Santiago de los Caballeros Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Why use momondo?

Why should I use momondo to find a flight deal from Portland to Santiago de los Caballeros?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Portland to Santiago de los Caballeros. momondo saves you time and could save you money on your trip.

Can I find flights from Portland to Santiago de los Caballeros with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Santiago de los Caballeros from Portland with this policy.

How can momondo help me find flights from Portland to Santiago de los Caballeros?

Once all potential Portland to Santiago de los Caballeros flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Portland to Santiago de los Caballeros right now. Can momondo alert me if prices change?

Price alerts on flights to Santiago de los Caballeros from Portland are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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