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Cheap flights from Portland, Maine to Santiago de los Caballeros from $560

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Portland, Maine to Santiago de los Caballeros departing on 10/25. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Find the cheapest flights from Portland, Maine to Santiago de los Caballeros

Cheap round-trip flights

Enter your travel dates to find the best prices.
JetBlue Logo
6:30 am - 1:54 pm
PWM
-
STI
7h 24m
1 stop
JetBlue Logo
3:29 pm - 11:43 pm
STI
-
PWM
8h 14m
1 stop
$560JetBlue
Sun, Oct 25 - Wed, Oct 28
JetBlue Logo
6:30 am - 1:54 pm
PWM
-
STI
7h 24m
1 stop
JetBlue Logo
3:29 pm - 11:43 pm
STI
-
PWM
8h 14m
1 stop
$562JetBlue
Sun, Oct 25 - Wed, Oct 28
United Airlines Logo
5:50 am - 10:51 pm
PWM
-
STI
17h 01m
1 stop
United Airlines Logo
5:00 am - 9:51 pm
STI
-
PWM
16h 51m
2 stops
$571United Airlines
Sun, Oct 25 - Wed, Oct 28
United Airlines Logo
5:50 am - 1:53 pm
PWM
-
STI
8h 03m
1 stop
United Airlines Logo
3:00 pm - 11:21 pm
STI
-
PWM
8h 21m
1 stop
$586United Airlines
Sun, Oct 25 - Wed, Oct 28
United Airlines Logo
5:50 am - 10:51 pm
PWM
-
STI
17h 01m
1 stop
United Airlines Logo
5:00 am - 9:51 pm
STI
-
PWM
16h 51m
2 stops
$591United Airlines
Sun, Oct 25 - Wed, Oct 28
United Airlines Logo
6:00 am - 10:52 pm
PWM
-
STI
40h 52m
2 stops
United Airlines Logo
6:00 am - 10:04 am
STI
-
PWM
28h 04m
2 stops
$665United Airlines
Sun, Sep 13 - Sun, Sep 20
United Airlines Logo
6:00 am - 10:52 pm
PWM
-
STI
40h 52m
2 stops
United Airlines Logo
6:00 am - 11:32 pm
STI
-
PWM
17h 32m
1 stop
$674United Airlines
Sun, Sep 13 - Sun, Sep 20
United Airlines Logo
6:06 am - 12:57 pm
PWM
-
STI
6h 51m
1 stop
United Airlines Logo
6:00 am - 11:32 pm
STI
-
PWM
17h 32m
1 stop
$758United Airlines
Sun, Sep 13 - Sun, Sep 20
United Airlines Logo
5:30 am - 10:51 pm
PWM
-
STI
17h 21m
2 stops
United Airlines Logo
5:00 am - 9:51 pm
STI
-
PWM
16h 51m
2 stops
$874United Airlines
Sun, Oct 25 - Wed, Oct 28
United Airlines Logo
8:47 am - 10:51 pm
PWM
-
STI
14h 04m
2 stops
United Airlines Logo
5:00 am - 9:51 pm
STI
-
PWM
16h 51m
2 stops
$894United Airlines
Sun, Oct 25 - Wed, Oct 28

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JetBlue flights from Portland, Maine to Santiago de los Caballeros

Our best JetBlue deals on Portland, Maine to Santiago de los Caballeros flight tickets
JetBlue
Oct 25
PWM6:30 amPortland
7h 24m
1 stop
STI1:54 pmSantiago de los Caballeros
Oct 28
STI3:29 pmSantiago de los Caballeros
8h 14m
1 stop
PWM11:43 pmPortland
$560
JetBlue
Oct 25
PWM6:30 amPortland
7h 24m
1 stop
STI1:54 pmSantiago de los Caballeros
Oct 28
STI3:29 pmSantiago de los Caballeros
8h 14m
1 stop
PWM11:43 pmPortland
$562

United Airlines flights from Portland, Maine to Santiago de los Caballeros

Our best United Airlines deals on Portland, Maine to Santiago de los Caballeros flight tickets
United Airlines
Oct 25
PWM5:50 amPortland
17h 01m
1 stop
STI10:51 pmSantiago de los Caballeros
Oct 28
STI5:00 amSantiago de los Caballeros
16h 51m
2 stops
PWM9:51 pmPortland
$571
United Airlines
Oct 25
PWM5:50 amPortland
8h 03m
1 stop
STI1:53 pmSantiago de los Caballeros
Oct 28
STI3:00 pmSantiago de los Caballeros
8h 21m
1 stop
PWM11:21 pmPortland
$586
United Airlines
Oct 25
PWM5:50 amPortland
17h 01m
1 stop
STI10:51 pmSantiago de los Caballeros
Oct 28
STI5:00 amSantiago de los Caballeros
16h 51m
2 stops
PWM9:51 pmPortland
$591

momondo Fare Finder

 
Customize your flight search to find flights from Portland, Maine to Santiago de los Caballeros that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated July 31, 2026.
Use the filters below to find and compare flights from Portland, Maine to Santiago de los Caballeros that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

PortlandSantiago de los Caballeros

PWM - STI

PWMSTI

Portland

Sun 10/25

6:30 am-1:54 pm

1 stop7h 24m

Santiago de los Caballeros

Wed 10/28

3:29 pm-11:43 pm

1 stop8h 14m

$560

PortlandSantiago de los Caballeros

PWM - STI

PWMSTI

Portland

Sun 10/25

6:30 am-1:54 pm

1 stop7h 24m

Santiago de los Caballeros

Wed 10/28

3:29 pm-11:43 pm

1 stop8h 14m

$562

PortlandSantiago de los Caballeros

PWM - STI

PWMSTI

Portland

Sun 10/25

5:50 am-10:51 pm

1 stop17h 01m

Santiago de los Caballeros

Wed 10/28

5:00 am-9:51 pm

2 stops16h 51m

$571

PortlandSantiago de los Caballeros

PWM - STI

PWMSTI

Portland

Sun 10/25

5:50 am-1:53 pm

1 stop8h 03m

Santiago de los Caballeros

Wed 10/28

3:00 pm-11:21 pm

1 stop8h 21m

$586

PortlandSantiago de los Caballeros

PWM - STI

PWMSTI

Portland

Sun 10/25

5:50 am-10:51 pm

1 stop17h 01m

Santiago de los Caballeros

Wed 10/28

5:00 am-9:51 pm

2 stops16h 51m

$591

PortlandSantiago de los Caballeros

PWM - STI

PWMSTI

Portland

Sun 9/13

6:00 am-10:52 pm

2 stops40h 52m

Santiago de los Caballeros

Sun 9/20

6:00 am-10:04 am

2 stops28h 04m

$665

PortlandSantiago de los Caballeros

PWM - STI

PWMSTI

Portland

Sun 9/13

6:00 am-10:52 pm

2 stops40h 52m

Santiago de los Caballeros

Sun 9/20

6:00 am-11:32 pm

1 stop17h 32m

$674

PortlandSantiago de los Caballeros

PWM - STI

PWMSTI

Portland

Sun 9/13

6:06 am-12:57 pm

1 stop6h 51m

Santiago de los Caballeros

Sun 9/20

6:00 am-11:32 pm

1 stop17h 32m

$758

PortlandSantiago de los Caballeros

PWM - STI

PWMSTI

Portland

Sun 10/25

5:30 am-10:51 pm

2 stops17h 21m

Santiago de los Caballeros

Wed 10/28

5:00 am-9:51 pm

2 stops16h 51m

$874

PortlandSantiago de los Caballeros

PWM - STI

PWMSTI

Portland

Sun 10/25

8:47 am-10:51 pm

2 stops14h 04m

Santiago de los Caballeros

Wed 10/28

5:00 am-9:51 pm

2 stops16h 51m

$894

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to Santiago de los Caballeros from

How to get the cheapest flight ticket from Portland, Maine to Santiago de los Caballeros

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What airlines fly to Santiago de los Caballeros?

JetBlue, Arajet and American Airlines are the top three most popular airlines that fly to Santiago de los Caballeros from Portland, Maine according to our data. JetBlue is the first choice among our users, with 76% of people opting to fly with this airline when traveling to Santiago de los Caballeros. Keep in mind that there are 9 different airlines that fly to Santiago de los Caballeros on a routine basis, so you have a few additional options to choose from.

When to book flights from Portland, Maine to Santiago de los Caballeros

Are you open to changing your travel dates? Check out the ideal times to fly from Portland, Maine to Santiago de los Caballeros according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Portland, Maine to Santiago de los Caballeros (PWM to STI) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Portland, Maine to Santiago de los Caballeros

Fastest flight time

8h 03m

Direct flights

None
The fastest flight from Portland, Maine to Santiago de los Caballeros takes 8h 03m
There are no direct flights from Portland, Maine to Santiago de los Caballeros. There are no popular flight routes from Portland, Maine to Santiago de los Caballeros.
Search flight deals

Frequently asked questions about flying from Portland, Maine to Santiago de los Caballeros

  • How far is Portland to Santiago de los Caballeros by plane?

    The straight-line distance from Portland to Santiago de los Caballeros is 1671.8 mi. By plane, this route typically takes 8h 03m.

  • When did momondo last update prices for flights from Portland Airport to Santiago de los Caballeros Airport?

    Prices for flights from Portland Airport to Santiago de los Caballeros Airport refresh daily.

  • How old do you have to be to fly from Portland Airport to Santiago de los Caballeros Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Portland Airport to Santiago de los Caballeros Airport.

  • What documentation or ID do you need to fly to Santiago de los Caballeros Airport?

    The travel and health documents you'll need for your trip to Santiago de los Caballeros Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Santiago de los Caballeros Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Why use momondo?

Why should I use momondo to find a flight deal from Portland to Santiago de los Caballeros?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Portland to Santiago de los Caballeros. momondo saves you time and could save you money on your trip.

Can I find flights from Portland to Santiago de los Caballeros with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Santiago de los Caballeros from Portland with this policy.

How can momondo help me find flights from Portland to Santiago de los Caballeros?

Once all potential Portland to Santiago de los Caballeros flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Portland to Santiago de los Caballeros right now. Can momondo alert me if prices change?

Price alerts on flights to Santiago de los Caballeros from Portland are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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